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The map label for this gene is katX

Identifier: 16080914

GI number: 16080914

Start: 3964997

End: 3966640

Strand: Direct

Name: katX

Synonym: BSU38630

Alternate gene names: 16080914

Gene position: 3964997-3966640 (Clockwise)

Preceding gene: 255767817

Following gene: 16080915

Centisome position: 94.06

GC content: 47.57

Gene sequence:

>1644_bases
TTGAAAGATGATCATCAAAACAAGCAGCACCAATCAAATGCCCAAGGGAGCGAGGAAGCGTTTTCTCATAAGACATCCGG
GAAAAACGAGTCAGAGGATACCTTAACGAATAGGCAGGGGCATCCTGTTACTGACAACCAGAATGTGAGAACCGTCGGGA
ATAGAGGGCCTACAACACTTGAGAACTATGATTTTCTCGAAAAGATCAGCCACTTCGACCGGGAACGCATCCCAGAGCGG
GTTGTTCATGCCAGGGGAGCAGGTGCACATGGATATTTTGAAGCGTACGGAAGCTTCGGAGACGAACCGATTTCAACATA
CACAAGGGCCAAGCTCTTTCAGGAAAAAGGCAAGAAAACACCGGCATTTGTCCGTTTTTCAACTGTGAATCATGGAAAAC
ACTCGCCTGAAACATTGAGAGACCCGCGCGGTTTTGCTGTAAAGCTATATACAGAAGACGGAAACTGGGATTTGGTCGGA
AACAACCTGAAAATCTTTTTTATCCGCGACCCGCTGAAATTTCCGGATCTTGTACACGCATTTCAGCCTGATCCAGTGAC
AAACATCCAGGATGGTGAACGTATCTTCGATTTCATTTCTCAATCTCCTGAAGCGACACACATGATCACCTTCTTGTTTT
CGCCTTGGGGCATTCCGGCCAACTACCGGCAAATGCAGGGTTCAGGCGTACATGCCTATAAATGGGTGAATGAGGAGGGC
AAGGCCGTTCTCGTGAAATACCATTTTGAACCGAAGCAGGGCATCCGCAACCTGACACAGAAGGAAGCAGAAGAGATTCA
AGGGAAAAACTTTAACCATGCCACACAGGATCTATATGACGCGATTGAAAATGGCGATTATCCAGAGTGGGAAGTATATG
CTCAAATCATGAGCGATGATGAGCATCCTGAACTGGACTTTGATCCTCTTGATCCAACAAAACTGTGGTATAAAGACGAT
TTCCCATGGAAACCGATCGGCAAATTGGTTCTGAACAAAAATCCGGAAAACTACCATGCGGAAGTGGAGCAAGCTTCATT
TGGAACGGGAGTGCTTGTCGACGGGCTTGATTTTTCAGACGACAAATTGCTCCAGGGGCGTACGTTTGCCTACTCTGATA
CGCAGCGCTACCGTGTAGGCGCAAATTACCTGCAGCTTCCGATCAACTCGCCGAAAAAGCATGTCGCCACCAACCAGGAA
GGCGGGCAAATGCAATATCGGGTCGATAGAGCAGAAGGACAAAACCCGCACGTCAACTACGAGCCATCCATTATGGGCGG
GCTGAAGGAAGCGAAGCAAGACGGAAAAGACCATACGCCGCATGTCGAAGGTGATGTAAAGCGTGAAGCGATTGACAGAA
CAAACAACTTCGGACAGGCTGGAGAAACGTACCGGAGATTTACTGAATTTGAGCGGAACGAATTGATTACGAATTTGGTG
AATACGCTTTCTACGTGCCGAAAAGAAATTCAGGATCAAATGATTGAGAATTTCACAAAAGCTGATCCTGACTACGGAAA
ACGCGTAGCAGAAGGGCTAAAAAAGGTCTCCGAAAACAACAGCAACGGGCCGATCGGCACAACTGAAACGGAACAGGCTG
CAAAGCAGGCTGAACAGGAGAGTCATCCGTCTGATCCGTATTAA

Upstream 100 bases:

>100_bases
GTACATTGTACCATTCCCGAAGCAGATCAAAAAAAACGGCTGTTTTAAAATCTTTCCATTCAGGGAATATTGTTACCGTT
CAAAAAAGGAGGGCCAACCA

Downstream 100 bases:

>100_bases
CAACAGCGAACAGGGCTTTTTTAGAAGCCCTGTTTTTTTATTTTTCTATTGAAACGCTTTCAATAATTGTGTTGTACTTG
GAAGGAAAGGGGTGGAGAGA

Product: major catalase in spores

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MKDDHQNKQHQSNAQGSEEAFSHKTSGKNESEDTLTNRQGHPVTDNQNVRTVGNRGPTTLENYDFLEKISHFDRERIPER
VVHARGAGAHGYFEAYGSFGDEPISTYTRAKLFQEKGKKTPAFVRFSTVNHGKHSPETLRDPRGFAVKLYTEDGNWDLVG
NNLKIFFIRDPLKFPDLVHAFQPDPVTNIQDGERIFDFISQSPEATHMITFLFSPWGIPANYRQMQGSGVHAYKWVNEEG
KAVLVKYHFEPKQGIRNLTQKEAEEIQGKNFNHATQDLYDAIENGDYPEWEVYAQIMSDDEHPELDFDPLDPTKLWYKDD
FPWKPIGKLVLNKNPENYHAEVEQASFGTGVLVDGLDFSDDKLLQGRTFAYSDTQRYRVGANYLQLPINSPKKHVATNQE
GGQMQYRVDRAEGQNPHVNYEPSIMGGLKEAKQDGKDHTPHVEGDVKREAIDRTNNFGQAGETYRRFTEFERNELITNLV
NTLSTCRKEIQDQMIENFTKADPDYGKRVAEGLKKVSENNSNGPIGTTETEQAAKQAEQESHPSDPY

Sequences:

>Translated_547_residues
MKDDHQNKQHQSNAQGSEEAFSHKTSGKNESEDTLTNRQGHPVTDNQNVRTVGNRGPTTLENYDFLEKISHFDRERIPER
VVHARGAGAHGYFEAYGSFGDEPISTYTRAKLFQEKGKKTPAFVRFSTVNHGKHSPETLRDPRGFAVKLYTEDGNWDLVG
NNLKIFFIRDPLKFPDLVHAFQPDPVTNIQDGERIFDFISQSPEATHMITFLFSPWGIPANYRQMQGSGVHAYKWVNEEG
KAVLVKYHFEPKQGIRNLTQKEAEEIQGKNFNHATQDLYDAIENGDYPEWEVYAQIMSDDEHPELDFDPLDPTKLWYKDD
FPWKPIGKLVLNKNPENYHAEVEQASFGTGVLVDGLDFSDDKLLQGRTFAYSDTQRYRVGANYLQLPINSPKKHVATNQE
GGQMQYRVDRAEGQNPHVNYEPSIMGGLKEAKQDGKDHTPHVEGDVKREAIDRTNNFGQAGETYRRFTEFERNELITNLV
NTLSTCRKEIQDQMIENFTKADPDYGKRVAEGLKKVSENNSNGPIGTTETEQAAKQAEQESHPSDPY
>Mature_547_residues
MKDDHQNKQHQSNAQGSEEAFSHKTSGKNESEDTLTNRQGHPVTDNQNVRTVGNRGPTTLENYDFLEKISHFDRERIPER
VVHARGAGAHGYFEAYGSFGDEPISTYTRAKLFQEKGKKTPAFVRFSTVNHGKHSPETLRDPRGFAVKLYTEDGNWDLVG
NNLKIFFIRDPLKFPDLVHAFQPDPVTNIQDGERIFDFISQSPEATHMITFLFSPWGIPANYRQMQGSGVHAYKWVNEEG
KAVLVKYHFEPKQGIRNLTQKEAEEIQGKNFNHATQDLYDAIENGDYPEWEVYAQIMSDDEHPELDFDPLDPTKLWYKDD
FPWKPIGKLVLNKNPENYHAEVEQASFGTGVLVDGLDFSDDKLLQGRTFAYSDTQRYRVGANYLQLPINSPKKHVATNQE
GGQMQYRVDRAEGQNPHVNYEPSIMGGLKEAKQDGKDHTPHVEGDVKREAIDRTNNFGQAGETYRRFTEFERNELITNLV
NTLSTCRKEIQDQMIENFTKADPDYGKRVAEGLKKVSENNSNGPIGTTETEQAAKQAEQESHPSDPY

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family

Homologues:

Organism=Homo sapiens, GI4557014, Length=500, Percent_Identity=43.4, Blast_Score=416, Evalue=1e-116,
Organism=Escherichia coli, GI48994891, Length=528, Percent_Identity=40.530303030303, Blast_Score=362, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71998444, Length=484, Percent_Identity=43.3884297520661, Blast_Score=423, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI25151141, Length=488, Percent_Identity=42.827868852459, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI25147792, Length=482, Percent_Identity=43.1535269709544, Blast_Score=419, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6320462, Length=361, Percent_Identity=44.0443213296399, Blast_Score=326, Evalue=6e-90,
Organism=Saccharomyces cerevisiae, GI6321525, Length=360, Percent_Identity=38.3333333333333, Blast_Score=268, Evalue=2e-72,
Organism=Drosophila melanogaster, GI17981717, Length=502, Percent_Identity=40.4382470119522, Blast_Score=393, Evalue=1e-109,
Organism=Drosophila melanogaster, GI19920968, Length=489, Percent_Identity=39.0593047034765, Blast_Score=379, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CATX_BACSU (P94377)

Other databases:

- EMBL:   D83026
- EMBL:   AL009126
- PIR:   E69647
- RefSeq:   NP_391742.1
- ProteinModelPortal:   P94377
- SMR:   P94377
- PeroxiBase:   4078
- EnsemblBacteria:   EBBACT00000000645
- GeneID:   937399
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38630
- NMPDR:   fig|224308.1.peg.3868
- GenoList:   BSU38630
- GeneTree:   EBGT00050000002743
- HOGENOM:   HBG339355
- OMA:   TFSYSDT
- PhylomeDB:   P94377
- ProtClustDB:   CLSK872985
- BioCyc:   BSUB:BSU38630-MONOMER
- BRENDA:   1.11.1.6
- GO:   GO:0005737
- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- Gene3D:   G3DSA:2.40.180.10
- PANTHER:   PTHR11465
- PRINTS:   PR00067

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; SSF56634 Catalase_N

EC number: =1.11.1.6

Molecular weight: Translated: 62364; Mature: 62364

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00437 CATALASE_1; PS00438 CATALASE_2; PS51402 CATALASE_3

Important sites: ACT_SITE 83-83 ACT_SITE 161-161

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDDHQNKQHQSNAQGSEEAFSHKTSGKNESEDTLTNRQGHPVTDNQNVRTVGNRGPTTL
CCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEEECCCCCCCCC
ENYDFLEKISHFDRERIPERVVHARGAGAHGYFEAYGSFGDEPISTYTRAKLFQEKGKKT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
PAFVRFSTVNHGKHSPETLRDPRGFAVKLYTEDGNWDLVGNNLKIFFIRDPLKFPDLVHA
CEEEEEEECCCCCCCCHHHCCCCCCEEEEEEECCCEEEECCCEEEEEEECCCCCHHHHHH
FQPDPVTNIQDGERIFDFISQSPEATHMITFLFSPWGIPANYRQMQGSGVHAYKWVNEEG
CCCCCCCCCCCHHHHHHHHHCCCCHHEEEEEEECCCCCCCCHHHHCCCCCEEEEEECCCC
KAVLVKYHFEPKQGIRNLTQKEAEEIQGKNFNHATQDLYDAIENGDYPEWEVYAQIMSDD
CEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCC
EHPELDFDPLDPTKLWYKDDFPWKPIGKLVLNKNPENYHAEVEQASFGTGVLVDGLDFSD
CCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCC
DKLLQGRTFAYSDTQRYRVGANYLQLPINSPKKHVATNQEGGQMQYRVDRAEGQNPHVNY
CCHHCCCEEEECCCCCEEECCCEEEECCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCC
EPSIMGGLKEAKQDGKDHTPHVEGDVKREAIDRTNNFGQAGETYRRFTEFERNELITNLV
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
NTLSTCRKEIQDQMIENFTKADPDYGKRVAEGLKKVSENNSNGPIGTTETEQAAKQAEQE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SHPSDPY
CCCCCCC
>Mature Secondary Structure
MKDDHQNKQHQSNAQGSEEAFSHKTSGKNESEDTLTNRQGHPVTDNQNVRTVGNRGPTTL
CCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEEECCCCCCCCC
ENYDFLEKISHFDRERIPERVVHARGAGAHGYFEAYGSFGDEPISTYTRAKLFQEKGKKT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
PAFVRFSTVNHGKHSPETLRDPRGFAVKLYTEDGNWDLVGNNLKIFFIRDPLKFPDLVHA
CEEEEEEECCCCCCCCHHHCCCCCCEEEEEEECCCEEEECCCEEEEEEECCCCCHHHHHH
FQPDPVTNIQDGERIFDFISQSPEATHMITFLFSPWGIPANYRQMQGSGVHAYKWVNEEG
CCCCCCCCCCCHHHHHHHHHCCCCHHEEEEEEECCCCCCCCHHHHCCCCCEEEEEECCCC
KAVLVKYHFEPKQGIRNLTQKEAEEIQGKNFNHATQDLYDAIENGDYPEWEVYAQIMSDD
CEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCC
EHPELDFDPLDPTKLWYKDDFPWKPIGKLVLNKNPENYHAEVEQASFGTGVLVDGLDFSD
CCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCC
DKLLQGRTFAYSDTQRYRVGANYLQLPINSPKKHVATNQEGGQMQYRVDRAEGQNPHVNY
CCHHCCCEEEECCCCCEEECCCEEEECCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCCC
EPSIMGGLKEAKQDGKDHTPHVEGDVKREAIDRTNNFGQAGETYRRFTEFERNELITNLV
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
NTLSTCRKEIQDQMIENFTKADPDYGKRVAEGLKKVSENNSNGPIGTTETEQAAKQAEQE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SHPSDPY
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377