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The map label for this gene is licC

Identifier: 16080909

GI number: 16080909

Start: 3960192

End: 3961550

Strand: Reverse

Name: licC

Synonym: BSU38580

Alternate gene names: 16080909

Gene position: 3961550-3960192 (Counterclockwise)

Preceding gene: 16080910

Following gene: 16080908

Centisome position: 93.97

GC content: 51.66

Gene sequence:

>1359_bases
GTGAATAAAGTCAATCAGATCTTAGAAGAAAAGGTCATGCCTATAGCGGGAAGAATTGCGGGACAGCGTCATTTGCAGGC
GCTGCGTGATGGTATCATCCTCACGATGCCCCTGATTATCATCGGTTCCTTTTTCCTCATCATTGGCAACCTCCCGATCC
CGGGATACGCTGAGTTTATGGCAAAAACGTTTGGCAGCTCCTGGTCTGAAAAACTGGCCTACCCAGTCGACGCGACCTTT
GAAATTATGGGTCTTGTCGCCGCGTTCGGCATTGCCTACCGGCTCGCCGAGAAATACGGTGTTGATGCCTTGTCGGCCGG
AGCCATTTCCCTTGCGGCATTTTTATTAGCAACACCTTATCAAGTGCCGTTTATGCCGGATGGCGCGACGAAAGAAATCA
TGGTTGGCGGCGGGATTCCGCTTTCGCTCATGGGAAGCAAAGGCTTATTTGTCGCCATGATTATCGCAATGGTGTCCACA
GAGATTTACCGCCTTATTATCCAGCGCAATTTAGTCTTCAAAATGCCGGACGGTGTCCCGCCGGCGGTAAGCAAGTCATT
TGTCGCGTTAATCCCCGGCTTTGCCGTCATCTTCCTAATTTGGGCAGCCCGGCTGATTGTTGAAGCGACACCGTTTGAAA
GCCTTCATAATATTGTAAGCGTTTTATTGGGGACTCCGCTTTCCATTCTGGGAGGAAGCCTTGGAGGAAGCCTTGTCGCC
GAAGCCGTCAAAATGCTTTTATGGGCCTGCGGCCTTCACGGTGCAAACATTGTTGGCGGCGTCATGGCACCGATTTGGTA
CGGCGCAATGGATGCCAACCGGATCGCATTCCAAGCCGGTGAGGAGCTTCCTAAGATTTTCACCCAGCAATTTTTCGATA
TCTGGGTCAATATTGGCGGAAGCGGCGCCACATTGGCACTGGTTGTCACGATGTTCCTGCGCGCCCGAAGCAAACAAATG
AAGCAGCTCGGGAAGCTTGCGGTCGGCCCGGCCATCTTCAATATTAACGAACCGATTATATTCGGAATGCCGATCGTCAT
GAACCCAATGCTCTTACTTCCGTTTATCATCACGCCGCTTGTCACAGTGACACTCACGTACATCGGAATGAGCACCGGCC
TTGTCGCCAAACCGGCGGGTATCGCAGTGCCGTGGACCATGCCGCCGATCTTTTCAGGCTACTTGGCGACAGGAGGAAAA
GTCTCAGGCGCGGTCATGCAAGCCATTAATATTGCCGTGTCCTTTGTTGTCTACTATCCATTCTTCAGAATGTGGGATAA
GCAGAAGCTGAAAGAAGAAAACGATCTGGAGCTGGTCCAAACGCCTGCAGCAACAGATGACAAAGAAGCGGCTCTGTAG

Upstream 100 bases:

>100_bases
AGACGTCATTAATACCGTCCATTATGGAACGTGCAATGGGGCGGAAGTGCTGAAATCAGCTGAACAGCTTGGACATGTGT
CATAGAGAGGGGCGGGCTAT

Downstream 100 bases:

>100_bases
AGAAAGGAAGTGAATCGCGTGAATGAGGAAATGGAACAAATCATTTTTCAAATCATCCTTCACGGAGGAAACGGTAGGAG
CTCCGCAATGGAGGCCATTG

Product: phosphotransferase system (PTS) lichenan-specific enzyme IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNKVNQILEEKVMPIAGRIAGQRHLQALRDGIILTMPLIIIGSFFLIIGNLPIPGYAEFMAKTFGSSWSEKLAYPVDATF
EIMGLVAAFGIAYRLAEKYGVDALSAGAISLAAFLLATPYQVPFMPDGATKEIMVGGGIPLSLMGSKGLFVAMIIAMVST
EIYRLIIQRNLVFKMPDGVPPAVSKSFVALIPGFAVIFLIWAARLIVEATPFESLHNIVSVLLGTPLSILGGSLGGSLVA
EAVKMLLWACGLHGANIVGGVMAPIWYGAMDANRIAFQAGEELPKIFTQQFFDIWVNIGGSGATLALVVTMFLRARSKQM
KQLGKLAVGPAIFNINEPIIFGMPIVMNPMLLLPFIITPLVTVTLTYIGMSTGLVAKPAGIAVPWTMPPIFSGYLATGGK
VSGAVMQAINIAVSFVVYYPFFRMWDKQKLKEENDLELVQTPAATDDKEAAL

Sequences:

>Translated_452_residues
MNKVNQILEEKVMPIAGRIAGQRHLQALRDGIILTMPLIIIGSFFLIIGNLPIPGYAEFMAKTFGSSWSEKLAYPVDATF
EIMGLVAAFGIAYRLAEKYGVDALSAGAISLAAFLLATPYQVPFMPDGATKEIMVGGGIPLSLMGSKGLFVAMIIAMVST
EIYRLIIQRNLVFKMPDGVPPAVSKSFVALIPGFAVIFLIWAARLIVEATPFESLHNIVSVLLGTPLSILGGSLGGSLVA
EAVKMLLWACGLHGANIVGGVMAPIWYGAMDANRIAFQAGEELPKIFTQQFFDIWVNIGGSGATLALVVTMFLRARSKQM
KQLGKLAVGPAIFNINEPIIFGMPIVMNPMLLLPFIITPLVTVTLTYIGMSTGLVAKPAGIAVPWTMPPIFSGYLATGGK
VSGAVMQAINIAVSFVVYYPFFRMWDKQKLKEENDLELVQTPAATDDKEAAL
>Mature_452_residues
MNKVNQILEEKVMPIAGRIAGQRHLQALRDGIILTMPLIIIGSFFLIIGNLPIPGYAEFMAKTFGSSWSEKLAYPVDATF
EIMGLVAAFGIAYRLAEKYGVDALSAGAISLAAFLLATPYQVPFMPDGATKEIMVGGGIPLSLMGSKGLFVAMIIAMVST
EIYRLIIQRNLVFKMPDGVPPAVSKSFVALIPGFAVIFLIWAARLIVEATPFESLHNIVSVLLGTPLSILGGSLGGSLVA
EAVKMLLWACGLHGANIVGGVMAPIWYGAMDANRIAFQAGEELPKIFTQQFFDIWVNIGGSGATLALVVTMFLRARSKQM
KQLGKLAVGPAIFNINEPIIFGMPIVMNPMLLLPFIITPLVTVTLTYIGMSTGLVAKPAGIAVPWTMPPIFSGYLATGGK
VSGAVMQAINIAVSFVVYYPFFRMWDKQKLKEENDLELVQTPAATDDKEAAL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain

Homologues:

Organism=Escherichia coli, GI1788032, Length=476, Percent_Identity=32.3529411764706, Blast_Score=215, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTJC_BACSU (P46317)

Other databases:

- EMBL:   Z49992
- EMBL:   D83026
- EMBL:   AL009126
- PIR:   F69651
- RefSeq:   NP_391737.1
- ProteinModelPortal:   P46317
- EnsemblBacteria:   EBBACT00000002175
- GeneID:   937375
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38580
- NMPDR:   fig|224308.1.peg.3863
- GenoList:   BSU38580
- GeneTree:   EBGT00050000001946
- HOGENOM:   HBG532931
- OMA:   IINISAF
- PhylomeDB:   P46317
- ProtClustDB:   CLSK888108
- BioCyc:   BSUB:BSU38580-MONOMER
- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501
- TIGRFAMs:   TIGR00359
- TIGRFAMs:   TIGR00410

Pfam domain/function: PF02378 PTS_EIIC

EC number: NA

Molecular weight: Translated: 48535; Mature: 48535

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x133e8b24)-; HASH(0x1321ab90)-; HASH(0x134236a8)-; HASH(0xc3873b4)-; HASH(0x1314f1fc)-; HASH(0x13206cac)-; HASH(0x13447368)-; HASH(0x13464640)-; HASH(0x133f95d0)-; HASH(0x133be71c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCEEECCCCCCCCCCCH
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCEEECCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377