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The map label for this gene is ywfH

Identifier: 16080820

GI number: 16080820

Start: 3867493

End: 3868272

Strand: Direct

Name: ywfH

Synonym: BSU37680

Alternate gene names: 16080820

Gene position: 3867493-3868272 (Clockwise)

Preceding gene: 161511066

Following gene: 16080843

Centisome position: 91.74

GC content: 45.64

Gene sequence:

>780_bases
TTGTCAAAACGAACCGCATTTGTTATGGGAGCCAGTCAAGGGATCGGGAAAGCAATCGCTCTGAAATTAGCAGACCAGCA
CTTTTCCCTCGTCATTAATTCGCGAAATTTGGATAATATTGAATCTGTCAAAGAAGACATTTTGGCCAAGCATCCTGAGG
CGAGCGTCATTGTCCTTGCGGGCGATATGTCTGACCAGCATACGAGAGCGGGCATTTTTCAGAAAATCGAATCTCAATGC
GGACGGCTTGATGTTCTGATTAATAATATCCCGGGCGGCGCGCCTGACACATTTGATAACTGCAATATAGAGGATATGAC
GGCCACGTTCACTCAAAAGACCGTTGCCTATATTGACGCAATCAAGCGTGCTTCCTCACTGATGAAACAAAACGAGTTTG
GCAGAATCATCAACATTGTCGGAAATCTGTGGAAAGAACCCGGCGCCAACATGTTCACAAACAGTATGATGAATGCCGCT
TTAATTAACGCCAGTAAAAATATTTCCATCCAGCTTGCTCCTCACAACATTACTGTCAACTGTCTGAATCCTGGTTTTAT
CGCTACAGACCGTTATCATCAATTTGTGGAAAATGTGATGAAAAAGAACAGCATATCCAAACAGAAAGCAGAAGAACAGA
TTGCTTCCGGGATTCCGATGAAACGGGTCGGATCAGCCGAAGAAACCGCAGCGCTCGCCGCATTTCTTGCCTCTGAGGAA
GCCTCCTACATCACGGGACAGCAAATTTCCGCTGACGGCGGCAGCATGAAAAGCATATAA

Upstream 100 bases:

>100_bases
TCAATTCTCCTTTATCAGAATTTAAATAAAATTTGCTATTTTCTTCGTTTTTTCTTACGATGTAGATAATAATCCATTTT
TTTCAAAGGGGTGCAGTTAT

Downstream 100 bases:

>100_bases
AAACATCCCGCTTTTTAGCGGGATGTTTCTTGTAATGACCCGAACGGCAGGTTCAGCTTTTGAATCCGCGTGACAAATTC
CCGCAGATCCTCCTGCTTCG

Product: carrier protein reductase of bacilysin synthesis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDMSDQHTRAGIFQKIESQC
GRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAA
LINASKNISIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEE
ASYITGQQISADGGSMKSI

Sequences:

>Translated_259_residues
MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDMSDQHTRAGIFQKIESQC
GRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAA
LINASKNISIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEE
ASYITGQQISADGGSMKSI
>Mature_258_residues
SKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDMSDQHTRAGIFQKIESQCG
RLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAAL
INASKNISIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEEA
SYITGQQISADGGSMKSI

Specific function: Along with the bacABCDE operon is involved in bacilysin biosynthesis

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=26.5060240963855, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI32483357, Length=266, Percent_Identity=27.4436090225564, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI19923817, Length=270, Percent_Identity=27.4074074074074, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI5031737, Length=265, Percent_Identity=27.1698113207547, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI126723750, Length=264, Percent_Identity=25, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI10190704, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI15277342, Length=267, Percent_Identity=25.0936329588015, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=27.0992366412214, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367175, Length=261, Percent_Identity=29.5019157088123, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787335, Length=261, Percent_Identity=32.183908045977, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=27.843137254902, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=25.0965250965251, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=24.609375, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=25, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=27.3076923076923, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790717, Length=264, Percent_Identity=25, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=21.5686274509804, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=23.4848484848485, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI2367365, Length=258, Percent_Identity=25.968992248062, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=28.5171102661597, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=30.188679245283, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=27.7566539923954, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=27.8195488721804, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=29.8507462686567, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=274, Percent_Identity=26.2773722627737, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=26.4925373134328, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=25.7575757575758, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=26.1363636363636, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=28.3582089552239, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=275, Percent_Identity=25.8181818181818, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=28.3018867924528, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=26.0377358490566, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=271, Percent_Identity=28.7822878228782, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=29.4339622641509, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=26.8199233716475, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=262, Percent_Identity=24.4274809160305, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=24.9056603773585, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.9693486590038, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=26.5917602996255, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=26.9961977186312, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=24.6268656716418, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=26.5151515151515, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=26.171875, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=30.1158301158301, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=30.6201550387597, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=27.734375, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571526, Length=261, Percent_Identity=29.1187739463602, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YWFH_BACSU (P39644)

Other databases:

- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S39741
- RefSeq:   NP_391648.1
- ProteinModelPortal:   P39644
- SMR:   P39644
- EnsemblBacteria:   EBBACT00000000948
- GeneID:   937215
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU37680
- NMPDR:   fig|224308.1.peg.3774
- GenoList:   BSU37680
- GeneTree:   EBGT00070000031990
- HOGENOM:   HBG750976
- OMA:   FIATDRY
- ProtClustDB:   CLSK888069
- BioCyc:   BSUB:BSU37680-MONOMER
- GO:   GO:0005488
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081

Pfam domain/function: PF00106 adh_short

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28022; Mature: 27891

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLA
CCCCEEEEEECCCCCCHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEE
GDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDA
CCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITVN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCEEEEEECCEEEEE
CLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEE
EECCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCC
ASYITGQQISADGGSMKSI
CCEECCCEEECCCCCCCCC
>Mature Secondary Structure 
SKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLA
CCCEEEEEECCCCCCHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEE
GDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDA
CCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITVN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCEEEEEECCEEEEE
CLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEE
EECCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCC
ASYITGQQISADGGSMKSI
CCEECCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377