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The map label for this gene is murAA

Identifier: 16080729

GI number: 16080729

Start: 3777949

End: 3779259

Strand: Reverse

Name: murAA

Synonym: BSU36760

Alternate gene names: 16080729

Gene position: 3779259-3777949 (Counterclockwise)

Preceding gene: 16080730

Following gene: 16080728

Centisome position: 89.65

GC content: 45.69

Gene sequence:

>1311_bases
TTGGAAAAAATCATCGTCCGCGGCGGTCAGAAGTTAAACGGCACAGTCAAAGTTGAAGGCGCTAAAAATGCCGTTTTACC
TGTTATCGCTGCATCTTTATTAGCAAGTGAAGAAAAAAGCGTAATTTGTGATGTACCTACGCTCTCCGATGTATATACAA
TTAACGAAGTGTTGCGTCATTTAGGAGCAGATGTGCATTTTGAAAATAATGAAGTGACTGTAAATGCTTCATACGCTTTG
CAAACTGAAGCACCTTTTGAATATGTTCGTAAAATGCGTGCGTCTGTGCTTGTCATGGGGCCGCTTCTTGCGCGTACAGG
TCATGCAAGAGTTGCACTTCCGGGCGGATGCGCAATTGGTTCCAGACCGATTGATCAGCATTTAAAAGGTTTTGAAGCAA
TGGGCGCAGAAATCAAAGTCGGTAATGGCTTCATTGAAGCTGAAGTAAAAGGCCGACTGCAAGGCGCAAAAATTTATCTG
GACTTCCCAAGTGTAGGAGCTACAGAGAACCTGATTATGGCAGCCGCTCTAGCTGAAGGAACAACAACGCTGGAAAACGT
GGCAAAAGAACCCGAAATCGTTGATTTAGCAAACTATATCAACGGCATGGGCGGAAAAATCCGCGGAGCTGGCACCGGCA
CCATCAAAATTGAAGGAGTCGAAAAGCTTCACGGCGTAAAACACCATATTATTCCTGACCGTATTGAAGCGGGCACATTT
ATGGTTGCTGCTGCAATCACTGAAGGAAACGTATTAGTAAAAGGAGCGGTTCCTGAGCACCTCACCTCTTTAATTGCAAA
AATGGAAGAGATGGGTGTAACAATTAAGGATGAAGGTGAAGGTCTGCGTGTCATCGGCCCGAAAGAGCTTAAACCGATTG
ACATCAAAACAATGCCTCACCCGGGCTTCCCGACTGATATGCAGTCACAAATGATGGCGCTTCTGCTTCGTGCAAGCGGC
ACAAGCATGATTACAGAAACCGTTTTTGAAAACCGTTTTATGCATGCGGAAGAATTCCGCCGTATGAATGGTGATATCAA
GATTGAAGGACGTTCTGTCATCATTAACGGTCCTGTACAGCTTCAGGGAGCTGAAGTTGCAGCGACTGATTTGCGTGCAG
GTGCAGCGCTGATTCTTGCGGGGTTAGTGGCTGAAGGTCACACACGTGTTACTGAATTGAAGCACTTAGACCGCGGTTAC
GTTGATTTCCATCAGAAGCTTGCCGCTCTGGGCGCAGACATCGAACGTGTAAATGATGAGTCTGCTTCTGAGCAAGAGAA
TAAAGAAGTCGTTTCTGACTTAAATGCATAA

Upstream 100 bases:

>100_bases
AAGTGCAGGAATGGGCGGAAAACATACCGTTACGGTTGGCACACCAATCGTTACGACTGAATATTAATATAGAGAATTTA
GGGACGCGGAGGGGAATACC

Downstream 100 bases:

>100_bases
ACTTACTTGAAAATCAGTATGTCACTCTGGCATACTGGTTTTTTATTTTTTGTGTATTATCATCATTATGCGCAAAATAG
CAAAAAAGAATACGTAAATG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MEKIIVRGGQKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRHLGADVHFENNEVTVNASYAL
QTEAPFEYVRKMRASVLVMGPLLARTGHARVALPGGCAIGSRPIDQHLKGFEAMGAEIKVGNGFIEAEVKGRLQGAKIYL
DFPSVGATENLIMAAALAEGTTTLENVAKEPEIVDLANYINGMGGKIRGAGTGTIKIEGVEKLHGVKHHIIPDRIEAGTF
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVTIKDEGEGLRVIGPKELKPIDIKTMPHPGFPTDMQSQMMALLLRASG
TSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQLQGAEVAATDLRAGAALILAGLVAEGHTRVTELKHLDRGY
VDFHQKLAALGADIERVNDESASEQENKEVVSDLNA

Sequences:

>Translated_436_residues
MEKIIVRGGQKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRHLGADVHFENNEVTVNASYAL
QTEAPFEYVRKMRASVLVMGPLLARTGHARVALPGGCAIGSRPIDQHLKGFEAMGAEIKVGNGFIEAEVKGRLQGAKIYL
DFPSVGATENLIMAAALAEGTTTLENVAKEPEIVDLANYINGMGGKIRGAGTGTIKIEGVEKLHGVKHHIIPDRIEAGTF
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVTIKDEGEGLRVIGPKELKPIDIKTMPHPGFPTDMQSQMMALLLRASG
TSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQLQGAEVAATDLRAGAALILAGLVAEGHTRVTELKHLDRGY
VDFHQKLAALGADIERVNDESASEQENKEVVSDLNA
>Mature_436_residues
MEKIIVRGGQKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRHLGADVHFENNEVTVNASYAL
QTEAPFEYVRKMRASVLVMGPLLARTGHARVALPGGCAIGSRPIDQHLKGFEAMGAEIKVGNGFIEAEVKGRLQGAKIYL
DFPSVGATENLIMAAALAEGTTTLENVAKEPEIVDLANYINGMGGKIRGAGTGTIKIEGVEKLHGVKHHIIPDRIEAGTF
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVTIKDEGEGLRVIGPKELKPIDIKTMPHPGFPTDMQSQMMALLLRASG
TSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQLQGAEVAATDLRAGAALILAGLVAEGHTRVTELKHLDRGY
VDFHQKLAALGADIERVNDESASEQENKEVVSDLNA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=50.2369668246445, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46701; Mature: 46701

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIIVRGGQKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRH
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH
LGADVHFENNEVTVNASYALQTEAPFEYVRKMRASVLVMGPLLARTGHARVALPGGCAIG
CCCCEEECCCEEEEEEEEEEECCCCHHHHHHHHHHEEEECHHHHCCCCCEEEECCCCCCC
SRPIDQHLKGFEAMGAEIKVGNGFIEAEVKGRLQGAKIYLDFPSVGATENLIMAAALAEG
CCCHHHHHHHHHHCCCEEEECCCEEEEEECCCCCEEEEEEECCCCCCCHHHHEEHHHHCC
TTTLENVAKEPEIVDLANYINGMGGKIRGAGTGTIKIEGVEKLHGVKHHIIPDRIEAGTF
CHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCEEEECCHHHHCCCHHCCCCCCCCCCEE
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVTIKDEGEGLRVIGPKELKPIDIKTMPH
EEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCEEEEECCC
PGFPTDMQSQMMALLLRASGTSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQ
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEEECCEE
LQGAEVAATDLRAGAALILAGLVAEGHTRVTELKHLDRGYVDFHQKLAALGADIERVNDE
ECCCEEEHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCC
SASEQENKEVVSDLNA
CCCHHHHHHHHHHCCC
>Mature Secondary Structure
MEKIIVRGGQKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRH
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH
LGADVHFENNEVTVNASYALQTEAPFEYVRKMRASVLVMGPLLARTGHARVALPGGCAIG
CCCCEEECCCEEEEEEEEEEECCCCHHHHHHHHHHEEEECHHHHCCCCCEEEECCCCCCC
SRPIDQHLKGFEAMGAEIKVGNGFIEAEVKGRLQGAKIYLDFPSVGATENLIMAAALAEG
CCCHHHHHHHHHHCCCEEEECCCEEEEEECCCCCEEEEEEECCCCCCCHHHHEEHHHHCC
TTTLENVAKEPEIVDLANYINGMGGKIRGAGTGTIKIEGVEKLHGVKHHIIPDRIEAGTF
CHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCEEEECCHHHHCCCHHCCCCCCCCCCEE
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVTIKDEGEGLRVIGPKELKPIDIKTMPH
EEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCEEEEECCC
PGFPTDMQSQMMALLLRASGTSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQ
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEEECCEE
LQGAEVAATDLRAGAALILAGLVAEGHTRVTELKHLDRGYVDFHQKLAALGADIERVNDE
ECCCEEEHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCC
SASEQENKEVVSDLNA
CCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA