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The map label for this gene is pncA

Identifier: 16080227

GI number: 16080227

Start: 3260891

End: 3261442

Strand: Reverse

Name: pncA

Synonym: BSU31760

Alternate gene names: 16080227

Gene position: 3261442-3260891 (Counterclockwise)

Preceding gene: 16080228

Following gene: 16080226

Centisome position: 77.37

GC content: 42.93

Gene sequence:

>552_bases
ATGAAAAAAGCACTTATTTGTATTGATTATACGAATGATTTTGTGGCGAGTGACGGAAAATTGACCTGCGGGGAGCCCGG
CAGAATGATTGAAGAGGCGATCGTCAATTTAACTAAAGAATTCATCACAAACGGTGATTACGTCGTATTAGCAGTAGATT
CTCATGATGAAGGGGATCAATATCACCCTGAAACCCGTCTTTTTCCTCCGCATAATATAAAAGGCACGGAAGGAAAAGAT
CTGTACGGAAAGCTTTTGCCTCTATATCAGAAACATGAACATGAACCTAATGTTTACTACATGGAAAAAACGAGATATTC
TGCTTTTGCGGGAACTGATTTAGAGCTCAAACTCAGAGAGCGGCAGATTGGCGAACTGCATCTTGCCGGTGTCTGCACAG
ATATTTGTGTGTTGCATACAGCTGTTGACGCATACAACAAAGGTTTTCGGATTGTTGTGCATAAACAAGCTGTTGCCAGC
TTTAATCAGGAGGGGCACGCATGGGCTCTTTCCCATTTTGCAAACAGCATCGGAGCGCAAGTGGCAGAGTAA

Upstream 100 bases:

>100_bases
GTAAGAGACAAACGGACCGTTTGTCTTTTTGTTCATGGCAATTCACTTACAACTGGAGATAAGATATAATGTTCTCATAC
TGATGGCGGGGAGGCCGGCT

Downstream 100 bases:

>100_bases
GGAAGGGGAAAAACAGTGTTAGAGTACGGATTTAAAGATGACAGCCTGTCATTACATACAGACCTTTATCAGATCAATAT
GGCGGAAACGTACTGGAGAG

Product: nicotinamidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKKALICIDYTNDFVASDGKLTCGEPGRMIEEAIVNLTKEFITNGDYVVLAVDSHDEGDQYHPETRLFPPHNIKGTEGKD
LYGKLLPLYQKHEHEPNVYYMEKTRYSAFAGTDLELKLRERQIGELHLAGVCTDICVLHTAVDAYNKGFRIVVHKQAVAS
FNQEGHAWALSHFANSIGAQVAE

Sequences:

>Translated_183_residues
MKKALICIDYTNDFVASDGKLTCGEPGRMIEEAIVNLTKEFITNGDYVVLAVDSHDEGDQYHPETRLFPPHNIKGTEGKD
LYGKLLPLYQKHEHEPNVYYMEKTRYSAFAGTDLELKLRERQIGELHLAGVCTDICVLHTAVDAYNKGFRIVVHKQAVAS
FNQEGHAWALSHFANSIGAQVAE
>Mature_183_residues
MKKALICIDYTNDFVASDGKLTCGEPGRMIEEAIVNLTKEFITNGDYVVLAVDSHDEGDQYHPETRLFPPHNIKGTEGKD
LYGKLLPLYQKHEHEPNVYYMEKTRYSAFAGTDLELKLRERQIGELHLAGVCTDICVLHTAVDAYNKGFRIVVHKQAVAS
FNQEGHAWALSHFANSIGAQVAE

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PNCA_BACSU (O32091)

Other databases:

- EMBL:   AL009126
- PIR:   C70008
- RefSeq:   NP_391054.1
- ProteinModelPortal:   O32091
- SMR:   O32091
- EnsemblBacteria:   EBBACT00000003796
- GeneID:   938863
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31760
- NMPDR:   fig|224308.1.peg.3179
- GenoList:   BSU31760
- GeneTree:   EBGT00050000000752
- HOGENOM:   HBG752434
- OMA:   LTGVCTD
- ProtClustDB:   CLSK887810
- BioCyc:   BSUB:BSU31760-MONOMER
- InterPro:   IPR000868
- Gene3D:   G3DSA:3.40.50.850

Pfam domain/function: PF00857 Isochorismatase; SSF52499 Iscrsm_hydrolase

EC number: NA

Molecular weight: Translated: 20523; Mature: 20523

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKALICIDYTNDFVASDGKLTCGEPGRMIEEAIVNLTKEFITNGDYVVLAVDSHDEGDQ
CCCEEEEEECCCCEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
YHPETRLFPPHNIKGTEGKDLYGKLLPLYQKHEHEPNVYYMEKTRYSAFAGTDLELKLRE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCEEEEECC
RQIGELHLAGVCTDICVLHTAVDAYNKGFRIVVHKQAVASFNQEGHAWALSHFANSIGAQ
CCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCEEHHHHHHHHHHHC
VAE
CCC
>Mature Secondary Structure
MKKALICIDYTNDFVASDGKLTCGEPGRMIEEAIVNLTKEFITNGDYVVLAVDSHDEGDQ
CCCEEEEEECCCCEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
YHPETRLFPPHNIKGTEGKDLYGKLLPLYQKHEHEPNVYYMEKTRYSAFAGTDLELKLRE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCEEEEECC
RQIGELHLAGVCTDICVLHTAVDAYNKGFRIVVHKQAVASFNQEGHAWALSHFANSIGAQ
CCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCEEHHHHHHHHHHHC
VAE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377