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The map label for this gene is yueK

Identifier: 16080226

GI number: 16080226

Start: 3259403

End: 3260875

Strand: Reverse

Name: yueK

Synonym: BSU31750

Alternate gene names: 16080226

Gene position: 3260875-3259403 (Counterclockwise)

Preceding gene: 16080227

Following gene: 16080225

Centisome position: 77.35

GC content: 45.35

Gene sequence:

>1473_bases
GTGTTAGAGTACGGATTTAAAGATGACAGCCTGTCATTACATACAGACCTTTATCAGATCAATATGGCGGAAACGTACTG
GAGAGACGGCATTCATGAAAAGAAAGCGATTTTTGAGCTGTTTTTCAGAAGGCTTCCGTTTGAAAATGGCTATGCCGTAT
TTGCGGGCTTGGAAAAAGCCATTGAATACTTGGAAAATTTCAAGTTTACGGATAGCGATTTGAGTTATTTACAGGATGAA
CTCGGGTATCATGAAGATTTTATTGAATATTTGCGCGGCTTATCTTTTACAGGTTCACTTTACTCCATGAAAGAAGGAGA
ACTCGTTTTTAACAATGAGCCGATTATGAGGGTGGAGGCACCCCTGGTAGAAGCGCAGCTGATTGAAACAGCTTTGCTCA
ACATTGTGAACTATCAAACATTAATCGCAACAAAGGCTGCCCGGATTAAAGGCGTCATCGGTGATGAAGTTGCGCTTGAA
TTCGGAACAAGACGGGCGCACGAAATGGATGCGGCCATGTGGGGAGCGAGAGCAGCCTTAATCGGCGGCTTTAGCGCGAC
AAGCAATGTAAGAGCCGGAAAGCGCTTTAATATCCCGGTTTCCGGCACACATGCGCATGCGCTTGTGCAGGCTTACCGCG
ATGAATATACAGCTTTCAAAAAATACGCGGAAACACATAAGGATTGCGTCTTCTTAGTTGACACGTATGACACGCTTCGT
TCAGGCATGCCGAACGCGATTAGGGTTGCCAAGGAATTCGGCGACCGCATTAATTTCATTGGCATCCGTCTGGACAGCGG
CGATTTGGCGTACCTGTCAAAAAAAGCCCGGAAAATGCTTGATGAAGCAGGATTTACAGATGCGAAGGTGATTGCTTCAA
GCGATTTGGATGAGCACACCATTATGAATTTAAAGGCTCAGGGAGCGCGCATTGATGTCTGGGGTGTCGGTACGAAGCTG
ATCACTGCCTATGACCAGCCGGCTCTCGGCGCAGTTTATAAACTCGTTGCCATTGAAGAAGACGGGAAAATGGTCGACAC
GATCAAAATTTCGTCCAATCCTGAAAAAGTGACGACACCGGGCAGAAAGAAAGTCTACCGCATTATTAATCAGTCCAACC
ATCATTCTGAAGGCGACTATATTGCGCTTTATGATGAGCAGGTGAATGATCAGAAGCGGCTCAGAATGTTCCACCCGGTT
CATACATTCATCAGCAAATTTGTCACGAATTTTTATGCGAAGGATCTTCATGAACTGATTTTTGAGAAGGGTATTCTTTG
CTACCAAAACCCTGAGATTTCAGACATACAGCAGTATGTGCAGGATAACCTCAGCCTGCTTTGGGAGGAATATAAGAGAA
TCAGCAAGCCGGAGGAATACCCGGTTGATTTAAGCGAGGACTGCTGGAGCAATAAAATGCAGCGGATCCACGAAGTGAAA
AGCAGAATTGAAGAAGAGCTTGAGGAAGAATAA

Upstream 100 bases:

>100_bases
AGCTGTTGCCAGCTTTAATCAGGAGGGGCACGCATGGGCTCTTTCCCATTTTGCAAACAGCATCGGAGCGCAAGTGGCAG
AGTAAGGAAGGGGAAAAACA

Downstream 100 bases:

>100_bases
AGAAAAACTGGCCTTTCATTCGCGAAGGGCCAGTTTTCTTTATGTATATATTATTTTTCATGTTTAGACAATTTTCGTCA
AATTATTTGATATACTTAGG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MLEYGFKDDSLSLHTDLYQINMAETYWRDGIHEKKAIFELFFRRLPFENGYAVFAGLEKAIEYLENFKFTDSDLSYLQDE
LGYHEDFIEYLRGLSFTGSLYSMKEGELVFNNEPIMRVEAPLVEAQLIETALLNIVNYQTLIATKAARIKGVIGDEVALE
FGTRRAHEMDAAMWGARAALIGGFSATSNVRAGKRFNIPVSGTHAHALVQAYRDEYTAFKKYAETHKDCVFLVDTYDTLR
SGMPNAIRVAKEFGDRINFIGIRLDSGDLAYLSKKARKMLDEAGFTDAKVIASSDLDEHTIMNLKAQGARIDVWGVGTKL
ITAYDQPALGAVYKLVAIEEDGKMVDTIKISSNPEKVTTPGRKKVYRIINQSNHHSEGDYIALYDEQVNDQKRLRMFHPV
HTFISKFVTNFYAKDLHELIFEKGILCYQNPEISDIQQYVQDNLSLLWEEYKRISKPEEYPVDLSEDCWSNKMQRIHEVK
SRIEEELEEE

Sequences:

>Translated_490_residues
MLEYGFKDDSLSLHTDLYQINMAETYWRDGIHEKKAIFELFFRRLPFENGYAVFAGLEKAIEYLENFKFTDSDLSYLQDE
LGYHEDFIEYLRGLSFTGSLYSMKEGELVFNNEPIMRVEAPLVEAQLIETALLNIVNYQTLIATKAARIKGVIGDEVALE
FGTRRAHEMDAAMWGARAALIGGFSATSNVRAGKRFNIPVSGTHAHALVQAYRDEYTAFKKYAETHKDCVFLVDTYDTLR
SGMPNAIRVAKEFGDRINFIGIRLDSGDLAYLSKKARKMLDEAGFTDAKVIASSDLDEHTIMNLKAQGARIDVWGVGTKL
ITAYDQPALGAVYKLVAIEEDGKMVDTIKISSNPEKVTTPGRKKVYRIINQSNHHSEGDYIALYDEQVNDQKRLRMFHPV
HTFISKFVTNFYAKDLHELIFEKGILCYQNPEISDIQQYVQDNLSLLWEEYKRISKPEEYPVDLSEDCWSNKMQRIHEVK
SRIEEELEEE
>Mature_490_residues
MLEYGFKDDSLSLHTDLYQINMAETYWRDGIHEKKAIFELFFRRLPFENGYAVFAGLEKAIEYLENFKFTDSDLSYLQDE
LGYHEDFIEYLRGLSFTGSLYSMKEGELVFNNEPIMRVEAPLVEAQLIETALLNIVNYQTLIATKAARIKGVIGDEVALE
FGTRRAHEMDAAMWGARAALIGGFSATSNVRAGKRFNIPVSGTHAHALVQAYRDEYTAFKKYAETHKDCVFLVDTYDTLR
SGMPNAIRVAKEFGDRINFIGIRLDSGDLAYLSKKARKMLDEAGFTDAKVIASSDLDEHTIMNLKAQGARIDVWGVGTKL
ITAYDQPALGAVYKLVAIEEDGKMVDTIKISSNPEKVTTPGRKKVYRIINQSNHHSEGDYIALYDEQVNDQKRLRMFHPV
HTFISKFVTNFYAKDLHELIFEKGILCYQNPEISDIQQYVQDNLSLLWEEYKRISKPEEYPVDLSEDCWSNKMQRIHEVK
SRIEEELEEE

Specific function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN)

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family

Homologues:

Organism=Homo sapiens, GI194394158, Length=514, Percent_Identity=32.8793774319066, Blast_Score=266, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71997952, Length=526, Percent_Identity=35.5513307984791, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI71997947, Length=526, Percent_Identity=35.5513307984791, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI71997955, Length=212, Percent_Identity=42.9245283018868, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24581587, Length=523, Percent_Identity=36.1376673040153, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI161076680, Length=204, Percent_Identity=46.078431372549, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24581595, Length=204, Percent_Identity=46.078431372549, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI28574709, Length=204, Percent_Identity=46.078431372549, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24581593, Length=204, Percent_Identity=46.078431372549, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24581591, Length=204, Percent_Identity=46.078431372549, Blast_Score=173, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PNCB_BACSU (O32090)

Other databases:

- EMBL:   AL009126
- PIR:   D70008
- RefSeq:   NP_391053.1
- HSSP:   Q830Y8
- ProteinModelPortal:   O32090
- SMR:   O32090
- EnsemblBacteria:   EBBACT00000002665
- GeneID:   937186
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31750
- NMPDR:   fig|224308.1.peg.3178
- GenoList:   BSU31750
- GeneTree:   EBGT00050000002270
- HOGENOM:   HBG292386
- OMA:   DSGDLEY
- ProtClustDB:   PRK09243
- BioCyc:   BSUB:BSU31750-MONOMER
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR006405
- InterPro:   IPR002638
- PANTHER:   PTHR11098:SF1
- PIRSF:   PIRSF000484
- TIGRFAMs:   TIGR01513

Pfam domain/function: PF04095 NAPRTase; SSF51690 Q_phspho_trans

EC number: =2.4.2.11

Molecular weight: Translated: 56180; Mature: 56180

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEYGFKDDSLSLHTDLYQINMAETYWRDGIHEKKAIFELFFRRLPFENGYAVFAGLEKA
CCCCCCCCCCCEEEEHEEEECCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IEYLENFKFTDSDLSYLQDELGYHEDFIEYLRGLSFTGSLYSMKEGELVFNNEPIMRVEA
HHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEECCCCCEEECCCCCEEEEC
PLVEAQLIETALLNIVNYQTLIATKAARIKGVIGDEVALEFGTRRAHEMDAAMWGARAAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
IGGFSATSNVRAGKRFNIPVSGTHAHALVQAYRDEYTAFKKYAETHKDCVFLVDTYDTLR
HCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHH
SGMPNAIRVAKEFGDRINFIGIRLDSGDLAYLSKKARKMLDEAGFTDAKVIASSDLDEHT
HCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHH
IMNLKAQGARIDVWGVGTKLITAYDQPALGAVYKLVAIEEDGKMVDTIKISSNPEKVTTP
EEEEECCCCEEEEEECCCEEEEECCCCHHHHHEEEEEEECCCCEEEEEEECCCCCCCCCC
GRKKVYRIINQSNHHSEGDYIALYDEQVNDQKRLRMFHPVHTFISKFVTNFYAKDLHELI
HHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEKGILCYQNPEISDIQQYVQDNLSLLWEEYKRISKPEEYPVDLSEDCWSNKMQRIHEVK
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
SRIEEELEEE
HHHHHHHHCC
>Mature Secondary Structure
MLEYGFKDDSLSLHTDLYQINMAETYWRDGIHEKKAIFELFFRRLPFENGYAVFAGLEKA
CCCCCCCCCCCEEEEHEEEECCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
IEYLENFKFTDSDLSYLQDELGYHEDFIEYLRGLSFTGSLYSMKEGELVFNNEPIMRVEA
HHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEECCCCCEEECCCCCEEEEC
PLVEAQLIETALLNIVNYQTLIATKAARIKGVIGDEVALEFGTRRAHEMDAAMWGARAAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
IGGFSATSNVRAGKRFNIPVSGTHAHALVQAYRDEYTAFKKYAETHKDCVFLVDTYDTLR
HCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHH
SGMPNAIRVAKEFGDRINFIGIRLDSGDLAYLSKKARKMLDEAGFTDAKVIASSDLDEHT
HCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHH
IMNLKAQGARIDVWGVGTKLITAYDQPALGAVYKLVAIEEDGKMVDTIKISSNPEKVTTP
EEEEECCCCEEEEEECCCEEEEECCCCHHHHHEEEEEEECCCCEEEEEEECCCCCCCCCC
GRKKVYRIINQSNHHSEGDYIALYDEQVNDQKRLRMFHPVHTFISKFVTNFYAKDLHELI
HHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEKGILCYQNPEISDIQQYVQDNLSLLWEEYKRISKPEEYPVDLSEDCWSNKMQRIHEVK
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
SRIEEELEEE
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377