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The map label for this gene is aroA

Identifier: 16080027

GI number: 16080027

Start: 3045445

End: 3046521

Strand: Reverse

Name: aroA

Synonym: BSU29750

Alternate gene names: 16080027

Gene position: 3046521-3045445 (Counterclockwise)

Preceding gene: 16080028

Following gene: 16080026

Centisome position: 72.27

GC content: 45.31

Gene sequence:

>1077_bases
ATGAGCAACACAGAGTTAGAGCTTTTAAGGCAGAAAGCAGACGAATTAAACCTACAAATTTTAAAATTAATCAACGAACG
CGGCAATGTTGTAAAAGAGATCGGTAAAGCGAAGGAAGCACAGGGTGTCAACCGATTTGACCCTGTCAGAGAACGCACAA
TGTTAAACAATATCATTGAAAACAATGACGGGCCGTTCGAAAATTCAACCATCCAGCACATTTTTAAAGAGATATTCAAA
GCCGGTTTAGAGCTTCAGGAAGAAGATCACAGCAAAGCGCTGCTTGTCTCCCGCAAGAAAAAACCTGAAGATACAATTGT
TGATATCAAAGGCGAAAAAATCGGAGACGGCCAGCAAAGATTCATTGTCGGCCCATGTGCGGTAGAGAGCTATGAGCAGG
TAGCTGAAGTCGCTGCAGCTGCGAAAAAACAAGGGATTAAAATTTTGCGCGGTGGAGCCTTTAAGCCTCGTACGAGCCCA
TACGATTTCCAAGGGCTTGGTGTTGAAGGCCTTCAAATTTTAAAACGTGTAGCGGATGAATTTGATCTGGCGGTTATCAG
TGAAATCGTAACTCCGGCTCATATCGAAGAAGCGCTGGACTACATTGATGTCATTCAAATCGGAGCGCGCAACATGCAAA
ACTTCGAATTGCTGAAAGCGGCCGGCGCCGTGAAAAAGCCAGTGCTTCTGAAGCGCGGTCTTGCTGCAACGATCTCTGAA
TTCATCAATGCTGCTGAATACATCATGTCACAAGGAAATGACCAAATTATCCTTTGTGAGCGCGGAATCAGAACATATGA
AACAGCAACGAGAAACACGCTGGATATTTCAGCTGTGCCGATTTTGAAACAAGAAACGCATTTGCCAGTCTTTGTTGATG
TTACGCATTCAACAGGCCGCCGTGACCTCTTGCTTCCGACAGCTAAAGCCGCTTTAGCGATCGGTGCTGATGGCGTAATG
GCTGAGGTTCACCCTGATCCGTCAGTCGCACTTTCTGACTCTGCTCAGCAAATGGCGATTCCTGAATTCGAAAAATGGCT
GAATGAACTGAAGCCAATGGTGAAAGTCAACGCTTAA

Upstream 100 bases:

>100_bases
AAATTTTTTGTATTTCAGTATTTCCATTTGGAATTACTTATAGTAAGATGCATGATAACTACAAAATAAAAAATGAATGT
GCAGGGAAAGGATGAAAAAA

Downstream 100 bases:

>100_bases
TTGAACAATCCAAAAGGCCGCGCCTGCGGCCTTTTTTTATGCTTTCTCGTTTATTTAGTTATAAAAACCAAGTATACGTT
TTCATCATCTATAAAAACGT

Product: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase

Products: NA

Alternate protein names: Phospho-2-dehydro-3-deoxyheptonate aldolase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; Chorismate mutase

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSNTELELLRQKADELNLQILKLINERGNVVKEIGKAKEAQGVNRFDPVRERTMLNNIIENNDGPFENSTIQHIFKEIFK
AGLELQEEDHSKALLVSRKKKPEDTIVDIKGEKIGDGQQRFIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSP
YDFQGLGVEGLQILKRVADEFDLAVISEIVTPAHIEEALDYIDVIQIGARNMQNFELLKAAGAVKKPVLLKRGLAATISE
FINAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGRRDLLLPTAKAALAIGADGVM
AEVHPDPSVALSDSAQQMAIPEFEKWLNELKPMVKVNA

Sequences:

>Translated_358_residues
MSNTELELLRQKADELNLQILKLINERGNVVKEIGKAKEAQGVNRFDPVRERTMLNNIIENNDGPFENSTIQHIFKEIFK
AGLELQEEDHSKALLVSRKKKPEDTIVDIKGEKIGDGQQRFIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSP
YDFQGLGVEGLQILKRVADEFDLAVISEIVTPAHIEEALDYIDVIQIGARNMQNFELLKAAGAVKKPVLLKRGLAATISE
FINAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGRRDLLLPTAKAALAIGADGVM
AEVHPDPSVALSDSAQQMAIPEFEKWLNELKPMVKVNA
>Mature_357_residues
SNTELELLRQKADELNLQILKLINERGNVVKEIGKAKEAQGVNRFDPVRERTMLNNIIENNDGPFENSTIQHIFKEIFKA
GLELQEEDHSKALLVSRKKKPEDTIVDIKGEKIGDGQQRFIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSPY
DFQGLGVEGLQILKRVADEFDLAVISEIVTPAHIEEALDYIDVIQIGARNMQNFELLKAAGAVKKPVLLKRGLAATISEF
INAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGRRDLLLPTAKAALAIGADGVMA
EVHPDPSVALSDSAQQMAIPEFEKWLNELKPMVKVNA

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 chorismate mutase domain

Homologues:

Organism=Escherichia coli, GI1787466, Length=209, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROG_BACSU (P39912)

Other databases:

- EMBL:   X65945
- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   S21418
- RefSeq:   NP_390853.1
- ProteinModelPortal:   P39912
- SMR:   P39912
- PhosSite:   P39912
- EnsemblBacteria:   EBBACT00000003496
- GeneID:   937853
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU29750
- NMPDR:   fig|224308.1.peg.2978
- GenoList:   BSU29750
- GeneTree:   EBGT00050000002473
- HOGENOM:   HBG575990
- OMA:   VPILKQE
- PhylomeDB:   P39912
- ProtClustDB:   PRK12595
- BioCyc:   BSUB:BSU29750-MONOMER
- BRENDA:   2.5.1.54
- BRENDA:   5.4.99.5
- InterPro:   IPR013785
- InterPro:   IPR002701
- InterPro:   IPR010954
- InterPro:   IPR020822
- InterPro:   IPR006218
- InterPro:   IPR006268
- Gene3D:   G3DSA:3.20.20.70
- Gene3D:   G3DSA:1.20.59.10
- PANTHER:   PTHR21057:SF1
- SMART:   SM00830
- TIGRFAMs:   TIGR01801
- TIGRFAMs:   TIGR01361

Pfam domain/function: PF01817 CM_2; PF00793 DAHP_synth_1

EC number: =2.5.1.54; =5.4.99.5

Molecular weight: Translated: 39540; Mature: 39409

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS51168 CHORISMATE_MUT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTELELLRQKADELNLQILKLINERGNVVKEIGKAKEAQGVNRFDPVRERTMLNNIIE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
NNDGPFENSTIQHIFKEIFKAGLELQEEDHSKALLVSRKKKPEDTIVDIKGEKIGDGQQR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEHCCCCCCCCCEEEECCCCCCCCCCE
FIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSPYDFQGLGVEGLQILKRVADE
EEECHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FDLAVISEIVTPAHIEEALDYIDVIQIGARNMQNFELLKAAGAVKKPVLLKRGLAATISE
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCCHHHHCCHHHHHHH
FINAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGR
HHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCCCC
RDLLLPTAKAALAIGADGVMAEVHPDPSVALSDSAQQMAIPEFEKWLNELKPMVKVNA
CEEECCHHHHHHEECCCCCEEEECCCCCEEECCCHHHHCCHHHHHHHHHCCHHEEECC
>Mature Secondary Structure 
SNTELELLRQKADELNLQILKLINERGNVVKEIGKAKEAQGVNRFDPVRERTMLNNIIE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
NNDGPFENSTIQHIFKEIFKAGLELQEEDHSKALLVSRKKKPEDTIVDIKGEKIGDGQQR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEHCCCCCCCCCEEEECCCCCCCCCCE
FIVGPCAVESYEQVAEVAAAAKKQGIKILRGGAFKPRTSPYDFQGLGVEGLQILKRVADE
EEECHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FDLAVISEIVTPAHIEEALDYIDVIQIGARNMQNFELLKAAGAVKKPVLLKRGLAATISE
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCCHHHHCCHHHHHHH
FINAAEYIMSQGNDQIILCERGIRTYETATRNTLDISAVPILKQETHLPVFVDVTHSTGR
HHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCCCC
RDLLLPTAKAALAIGADGVMAEVHPDPSVALSDSAQQMAIPEFEKWLNELKPMVKVNA
CEEECCHHHHHHEECCCCCEEEECCCCCEEECCCHHHHCCHHHHHHHHHCCHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7496534; 9387221; 9384377