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The map label for this gene is accA

Identifier: 16079972

GI number: 16079972

Start: 2987731

End: 2988708

Strand: Reverse

Name: accA

Synonym: BSU29200

Alternate gene names: 16079972

Gene position: 2988708-2987731 (Counterclockwise)

Preceding gene: 255767673

Following gene: 16079971

Centisome position: 70.9

GC content: 45.6

Gene sequence:

>978_bases
GTGGCTCCAAGATTAGAATTTGAAAAACCGGTGATTGAACTGCAAACCAAAATCGCCGAACTAAAAAAATTCACCCAAGA
TTCCGATATGGATCTAAGTGCGGAAATCGAACGGCTCGAAGACCGTCTCGCTAAGCTTCAGGATGATATTTACAAAAATT
TGAAGCCGTGGGACCGGGTTCAAATCGCGCGTCTGGCGGACCGTCCGACAACTCTTGATTATATCGAACACCTGTTTACC
GACTTTTTTGAATGTCACGGAGACAGAGCGTACGGGGACGATGAAGCCATTGTCGGCGGGATTGCGAAGTTCCACGGCCT
CCCTGTAACGGTAATCGGGCATCAGCGCGGCAAAGACACGAAGGAAAACCTAGTCCGCAATTTTGGGATGCCGCATCCAG
AAGGCTACAGAAAAGCGCTTCGTCTGATGAAACAGGCTGACAAATTTAACAGACCAATTATCTGTTTTATTGATACGAAG
GGGGCATACCCTGGACGAGCAGCTGAAGAAAGAGGACAAAGTGAAGCTATTGCCAAAAACCTGTTTGAGATGGCCGGCCT
TCGAGTGCCTGTTATCTGCATCGTCATTGGTGAAGGCGGAAGCGGCGGAGCCCTTGGTCTGGGTGTAGGCAATCACTTGC
ATATGCTGGAAAACTCTACTTATTCTGTTATTTCTCCGGAAGGTGCCGCGGCACTTTTATGGAAGGACTCCAGTCTTGCT
AAAAAAGCAGCAGAAACAATGAAAATCACTGCGCCGGATTTAAAAGAATTAGGTATTATAGATCATATGATTAAAGAAGT
AAAAGGCGGAGCGCACCATGATGTGAAGCTGCAGGCAAGCTATATGGACGAAACCCTTAAACAATCGTTAAAAACTTTAC
TGAAGCTGAGCGAAGAAGAATTAGTTCAGCAGCGTTATGAAAAATATAAAGCAATTGGCAAAGTCTCGGTTGAAGATCAA
TATATCGGGGTAAACTAA

Upstream 100 bases:

>100_bases
TATTAAAACATGGACAGCTTGATGCGGTTATTCATCGCGACGATATGAAAAAAACGTTAGAAAATCTGCTGGATATGCAT
CAAACAGGAGGTGACATTGA

Downstream 100 bases:

>100_bases
ATAAACGTGAAGCCTTTGGCTCACGTTTATTTTTTGTGACATTCCTTAAATTTTATTTAAAAACAATTTATTTAATTGTA
TAATAGGTAAGGTTTCATAG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAPRLEFEKPVIELQTKIAELKKFTQDSDMDLSAEIERLEDRLAKLQDDIYKNLKPWDRVQIARLADRPTTLDYIEHLFT
DFFECHGDRAYGDDEAIVGGIAKFHGLPVTVIGHQRGKDTKENLVRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTK
GAYPGRAAEERGQSEAIAKNLFEMAGLRVPVICIVIGEGGSGGALGLGVGNHLHMLENSTYSVISPEGAAALLWKDSSLA
KKAAETMKITAPDLKELGIIDHMIKEVKGGAHHDVKLQASYMDETLKQSLKTLLKLSEEELVQQRYEKYKAIGKVSVEDQ
YIGVN

Sequences:

>Translated_325_residues
MAPRLEFEKPVIELQTKIAELKKFTQDSDMDLSAEIERLEDRLAKLQDDIYKNLKPWDRVQIARLADRPTTLDYIEHLFT
DFFECHGDRAYGDDEAIVGGIAKFHGLPVTVIGHQRGKDTKENLVRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTK
GAYPGRAAEERGQSEAIAKNLFEMAGLRVPVICIVIGEGGSGGALGLGVGNHLHMLENSTYSVISPEGAAALLWKDSSLA
KKAAETMKITAPDLKELGIIDHMIKEVKGGAHHDVKLQASYMDETLKQSLKTLLKLSEEELVQQRYEKYKAIGKVSVEDQ
YIGVN
>Mature_324_residues
APRLEFEKPVIELQTKIAELKKFTQDSDMDLSAEIERLEDRLAKLQDDIYKNLKPWDRVQIARLADRPTTLDYIEHLFTD
FFECHGDRAYGDDEAIVGGIAKFHGLPVTVIGHQRGKDTKENLVRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTKG
AYPGRAAEERGQSEAIAKNLFEMAGLRVPVICIVIGEGGSGGALGLGVGNHLHMLENSTYSVISPEGAAALLWKDSSLAK
KAAETMKITAPDLKELGIIDHMIKEVKGGAHHDVKLQASYMDETLKQSLKTLLKLSEEELVQQRYEKYKAIGKVSVEDQY
IGVN

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=312, Percent_Identity=53.2051282051282, Blast_Score=330, Evalue=6e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_BACSU (O34847)

Other databases:

- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   G69580
- RefSeq:   NP_390798.1
- ProteinModelPortal:   O34847
- SMR:   O34847
- EnsemblBacteria:   EBBACT00000003494
- GeneID:   936367
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU29200
- NMPDR:   fig|224308.1.peg.2923
- GenoList:   BSU29200
- GeneTree:   EBGT00050000002181
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   O34847
- ProtClustDB:   PRK05724
- BioCyc:   BSUB:BSU29200-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36334; Mature: 36203

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPRLEFEKPVIELQTKIAELKKFTQDSDMDLSAEIERLEDRLAKLQDDIYKNLKPWDRV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QIARLADRPTTLDYIEHLFTDFFECHGDRAYGDDEAIVGGIAKFHGLPVTVIGHQRGKDT
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCH
KENLVRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTKGAYPGRAAEERGQSEAIAKN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCHHHHHHHH
LFEMAGLRVPVICIVIGEGGSGGALGLGVGNHLHMLENSTYSVISPEGAAALLWKDSSLA
HHHHHCCCEEEEEEEEECCCCCCEEEECCCCCCHHHCCCCEEEECCCCCEEEEECCHHHH
KKAAETMKITAPDLKELGIIDHMIKEVKGGAHHDVKLQASYMDETLKQSLKTLLKLSEEE
HHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHH
LVQQRYEKYKAIGKVSVEDQYIGVN
HHHHHHHHHHHHCCCEECCCEECCC
>Mature Secondary Structure 
APRLEFEKPVIELQTKIAELKKFTQDSDMDLSAEIERLEDRLAKLQDDIYKNLKPWDRV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QIARLADRPTTLDYIEHLFTDFFECHGDRAYGDDEAIVGGIAKFHGLPVTVIGHQRGKDT
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCH
KENLVRNFGMPHPEGYRKALRLMKQADKFNRPIICFIDTKGAYPGRAAEERGQSEAIAKN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCHHHHHHHH
LFEMAGLRVPVICIVIGEGGSGGALGLGVGNHLHMLENSTYSVISPEGAAALLWKDSSLA
HHHHHCCCEEEEEEEEECCCCCCEEEECCCCCCHHHCCCCEEEECCCCCEEEEECCHHHH
KKAAETMKITAPDLKELGIIDHMIKEVKGGAHHDVKLQASYMDETLKQSLKTLLKLSEEE
HHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHH
LVQQRYEKYKAIGKVSVEDQYIGVN
HHHHHHHHHHHHCCCEECCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377