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The map label for this gene is etfA

Identifier: 16079904

GI number: 16079904

Start: 2915365

End: 2916342

Strand: Reverse

Name: etfA

Synonym: BSU28520

Alternate gene names: 16079904

Gene position: 2916342-2915365 (Counterclockwise)

Preceding gene: 16079905

Following gene: 255767658

Centisome position: 69.18

GC content: 48.36

Gene sequence:

>978_bases
ATGGGAAAAAAAGTGATCGTGCTTGGAGAAATACGCGATGGGGAATTGCGAAATGTCACCTTTGAAGCAATAGCTGCAGG
AAGAACCATTTCAGGAGATGGGGAAGTCATCGGTGTTCTCATCGGTGAAAATGTACAAAGCATTGCACAAGAGCTTATTC
ATTACGGAGCAGATAAAGTTCTTACCGCTGAGGACCCGAAGCTGAAAACATACACGGCAGACGGGTACAGCCAGGTCATG
AGAGGTGTTATCGAGCAAGAAAATCCTGATTCAGTCATCTTCGGGCATACGGCAATGGGCAAGGATCTTTCACCGAAGCT
TGCTGCCCGTCTGCAAACAGGCTTAATTTCTGATGCTATAGATGTAAGCGTTACCGGAGGGAATGTTGTGTTCACACGGC
CGATTTACTCGGGGAAAGCTTTTGAACGCGTCATTTCAACCGATCCGATGATCTTTGCAACAATTCGCCCCAATAACATT
CAAGCTTCAGAAAAAGACACCAGCAGATCGGGGAGCATCGAAAGCATTGATGTTTCTCTTACTGACCTCCGCACTGTTAT
CCAAGAGGTCGTGAAAAAAACGGCGGACGGTGTTGATCTCTCCGAAGCGAAAATTATCGTTGCGGGCGGCCGAGGAGTCA
AAAGCAAGGAAGGATTTCAGCCGCTGCAGGAGCTTGCAGAGGTGCTAGGGGCCGCAGTCGGGGCTTCTCGCGGGGCATGT
GACGCTGATTATTGCGATTATGCTCTCCAAATCGGGCAGACCGGGAAAGTCGTTACTCCGGATTTGTACATTGCATGCGG
CATTTCCGGCGCCATCCAGCATTTGGCCGGCATGTCAAACAGCAAGGTGATCGTCGCCATCAATAAAGACCCCGAAGCCG
ATATCTTTAAAATAGCGGATTACGGCATCGTCGGTGATTTATTTGAAGTTGTCCCGTTATTAACTGAGGAATTCAAACAG
CTGAATATACACTCATAA

Upstream 100 bases:

>100_bases
GTGAGCCTGCTGAACAGGCAAAAGAGCTTGTTTCATTGCTCCGCAGCGAAGCTAAAGTCATTTAAAACTTGGACATTCAA
AGAAACAGGGGGATGTTAGA

Downstream 100 bases:

>100_bases
AGGAAATCCCGGACTTTAAAAGTCCGGGTTTTTTCATATTTATAAATACATACGTACAAATATAAAAACAATAGAAAATG
TCGTTGACATGTACGAACAT

Product: electron transfer flavoprotein alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENVQSIAQELIHYGADKVLTAEDPKLKTYTADGYSQVM
RGVIEQENPDSVIFGHTAMGKDLSPKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNI
QASEKDTSRSGSIESIDVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEGFQPLQELAEVLGAAVGASRGAC
DADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQ
LNIHS

Sequences:

>Translated_325_residues
MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENVQSIAQELIHYGADKVLTAEDPKLKTYTADGYSQVM
RGVIEQENPDSVIFGHTAMGKDLSPKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNI
QASEKDTSRSGSIESIDVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEGFQPLQELAEVLGAAVGASRGAC
DADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQ
LNIHS
>Mature_324_residues
GKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENVQSIAQELIHYGADKVLTAEDPKLKTYTADGYSQVMR
GVIEQENPDSVIFGHTAMGKDLSPKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNIQ
ASEKDTSRSGSIESIDVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEGFQPLQELAEVLGAAVGASRGACD
ADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQL
NIHS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family

Homologues:

Organism=Homo sapiens, GI4503607, Length=319, Percent_Identity=39.4984326018809, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI189181759, Length=280, Percent_Identity=41.7857142857143, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1787990, Length=275, Percent_Identity=33.4545454545455, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1786226, Length=243, Percent_Identity=34.9794238683128, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI87082157, Length=257, Percent_Identity=29.9610894941634, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=315, Percent_Identity=41.2698412698413, Blast_Score=211, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6325261, Length=289, Percent_Identity=36.3321799307958, Blast_Score=175, Evalue=8e-45,
Organism=Drosophila melanogaster, GI17136898, Length=318, Percent_Identity=42.1383647798742, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24652801, Length=318, Percent_Identity=42.1383647798742, Blast_Score=211, Evalue=7e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ETFA_BACSU (P94551)

Other databases:

- EMBL:   Z75208
- EMBL:   AL009126
- PIR:   D69620
- RefSeq:   NP_390730.1
- ProteinModelPortal:   P94551
- SMR:   P94551
- EnsemblBacteria:   EBBACT00000001254
- GeneID:   936520
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU28520
- NMPDR:   fig|224308.1.peg.2855
- GenoList:   BSU28520
- GeneTree:   EBGT00050000001708
- HOGENOM:   HBG615986
- OMA:   TDLRTVI
- PhylomeDB:   P94551
- ProtClustDB:   CLSK2518257
- BioCyc:   BSUB:BSU28520-MONOMER
- GO:   GO:0006810
- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF000089
- SMART:   SM00893

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha

EC number: NA

Molecular weight: Translated: 34542; Mature: 34411

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00696 ETF_ALPHA; PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENVQSIAQELIHYGADKV
CCCEEEEEEECCCCCCCCEEHHHHCCCCEECCCCCEEEEEECCCHHHHHHHHHHCCCCCE
LTAEDPKLKTYTADGYSQVMRGVIEQENPDSVIFGHTAMGKDLSPKLAARLQTGLISDAI
EECCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCE
DVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNIQASEKDTSRSGSIESIDVSL
EEEEECCCEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEH
TDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEGFQPLQELAEVLGAAVGASRGAC
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
DADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEADIFKIAD
CCHHHHHHHEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEC
YGIVGDLFEVVPLLTEEFKQLNIHS
CCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENVQSIAQELIHYGADKV
CCEEEEEEECCCCCCCCEEHHHHCCCCEECCCCCEEEEEECCCHHHHHHHHHHCCCCCE
LTAEDPKLKTYTADGYSQVMRGVIEQENPDSVIFGHTAMGKDLSPKLAARLQTGLISDAI
EECCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCE
DVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNIQASEKDTSRSGSIESIDVSL
EEEEECCCEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEH
TDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEGFQPLQELAEVLGAAVGASRGAC
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
DADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKVIVAINKDPEADIFKIAD
CCHHHHHHHEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEC
YGIVGDLFEVVPLLTEEFKQLNIHS
CCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377