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The map label for this gene is nadA

Identifier: 16079837

GI number: 16079837

Start: 2845955

End: 2847061

Strand: Reverse

Name: nadA

Synonym: BSU27850

Alternate gene names: 16079837

Gene position: 2847061-2845955 (Counterclockwise)

Preceding gene: 16079838

Following gene: 16079836

Centisome position: 67.54

GC content: 44.63

Gene sequence:

>1107_bases
ATGTCAATTCTTGATGTGATCAAACAATCGAATGATATGATGCCCGAAAGTTATAAAGAACTATCGAGAAAGGATATGGA
AACGCGCGTTGCCGCCATTAAGAAAAAGTTCGGCAGCAGGCTCTTTATACCAGGCCATCATTATCAAAAGGATGAAGTGA
TACAATTTGCTGACCAAACAGGCGACTCCCTGCAATTGGCCCAAGTAGCGGAAAAAAACAAAGAAGCGGATTATATCGTA
TTTTGCGGCGTTCACTTTATGGCAGAAACCGCCGATATGCTGACAAGCGAGCAGCAAACGGTCGTCCTGCCAGATATGAG
AGCTGGATGTTCTATGGCTGACATGGCTGACATGCAGCAGACCAATAGGGCATGGAAGAAGCTTCAGCATATATTTGGAG
ATACGATCATACCTTTAACTTATGTGAACTCCACTGCGGAGATCAAGGCATTCGTCGGAAAGCATGGCGGAGCAACTGTA
ACTTCTTCGAATGCGAAAAAAGTGCTTGAATGGGCGTTTACACAGAAAAAAAGAATTTTATTTTTGCCTGATCAGCATTT
AGGGAGAAATACGGCTTATGATCTGGGCATTGCGCTTGAAGATATGGCTGTGTGGGATCCGATGAAAGATGAATTAGTAG
CTGAATCCGGGCATACGAATGTGAAAGTGATTTTGTGGAAAGGGCATTGCTCTGTTCACGAGAAATTCACCACTAAAAAT
ATCCATGATATGAGAGAGCGAGACCCCGACATTCAGATCATTGTGCACCCGGAATGTTCACACGAAGTCGTGACACTAAG
CGATGATAACGGATCAACGAAATATATTATCGACACAATCAACCAGGCTCCGGCGGGAAGCAAGTGGGCAATCGGGACAG
AAATGAATCTTGTTCAGCGGATCATTCACGAGCATCCAGATAAACAAATCGAATCACTCAACCCTGACATGTGCCCTTGC
CTGACAATGAACCGAATTGATTTGCCGCATTTGTTGTGGTCGCTGGAACAAATTGAAAAAGGAGAACCTTCAGGCGTCAT
CAAGGTGCCAAAAGCCATTCAGGAAGATGCACTCCTTGCCCTGAATCGAATGCTTTCGATCACGTAG

Upstream 100 bases:

>100_bases
GTGAATTATATTTCATTAGGATTTCTGACTCATTCCGTCAAAAGTTTAGATATCAGCATGGATGTTACGTTATCAAATGA
ATCTGTGGAGGAATGCTGTT

Downstream 100 bases:

>100_bases
ATCAGAAATATTTTCCCTTCCTTTACTCATAACTTCTTTTGTTCAGGCATATGTTGTGAAGAAACATATTGTAATCACAG
CTGAACTGTTCACGTTTTGC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSILDVIKQSNDMMPESYKELSRKDMETRVAAIKKKFGSRLFIPGHHYQKDEVIQFADQTGDSLQLAQVAEKNKEADYIV
FCGVHFMAETADMLTSEQQTVVLPDMRAGCSMADMADMQQTNRAWKKLQHIFGDTIIPLTYVNSTAEIKAFVGKHGGATV
TSSNAKKVLEWAFTQKKRILFLPDQHLGRNTAYDLGIALEDMAVWDPMKDELVAESGHTNVKVILWKGHCSVHEKFTTKN
IHDMRERDPDIQIIVHPECSHEVVTLSDDNGSTKYIIDTINQAPAGSKWAIGTEMNLVQRIIHEHPDKQIESLNPDMCPC
LTMNRIDLPHLLWSLEQIEKGEPSGVIKVPKAIQEDALLALNRMLSIT

Sequences:

>Translated_368_residues
MSILDVIKQSNDMMPESYKELSRKDMETRVAAIKKKFGSRLFIPGHHYQKDEVIQFADQTGDSLQLAQVAEKNKEADYIV
FCGVHFMAETADMLTSEQQTVVLPDMRAGCSMADMADMQQTNRAWKKLQHIFGDTIIPLTYVNSTAEIKAFVGKHGGATV
TSSNAKKVLEWAFTQKKRILFLPDQHLGRNTAYDLGIALEDMAVWDPMKDELVAESGHTNVKVILWKGHCSVHEKFTTKN
IHDMRERDPDIQIIVHPECSHEVVTLSDDNGSTKYIIDTINQAPAGSKWAIGTEMNLVQRIIHEHPDKQIESLNPDMCPC
LTMNRIDLPHLLWSLEQIEKGEPSGVIKVPKAIQEDALLALNRMLSIT
>Mature_367_residues
SILDVIKQSNDMMPESYKELSRKDMETRVAAIKKKFGSRLFIPGHHYQKDEVIQFADQTGDSLQLAQVAEKNKEADYIVF
CGVHFMAETADMLTSEQQTVVLPDMRAGCSMADMADMQQTNRAWKKLQHIFGDTIIPLTYVNSTAEIKAFVGKHGGATVT
SSNAKKVLEWAFTQKKRILFLPDQHLGRNTAYDLGIALEDMAVWDPMKDELVAESGHTNVKVILWKGHCSVHEKFTTKNI
HDMRERDPDIQIIVHPECSHEVVTLSDDNGSTKYIIDTINQAPAGSKWAIGTEMNLVQRIIHEHPDKQIESLNPDMCPCL
TMNRIDLPHLLWSLEQIEKGEPSGVIKVPKAIQEDALLALNRMLSIT

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=335, Percent_Identity=26.5671641791045, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_BACSU (Q9KWZ1)

Other databases:

- EMBL:   Y15896
- EMBL:   AL009126
- PIR:   E69663
- RefSeq:   NP_390663.1
- ProteinModelPortal:   Q9KWZ1
- SMR:   Q9KWZ1
- EnsemblBacteria:   EBBACT00000000178
- GeneID:   937522
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU27850
- NMPDR:   fig|224308.1.peg.2788
- GenoList:   BSU27850
- GeneTree:   EBGT00050000002444
- HOGENOM:   HBG291157
- OMA:   IALEDMA
- PhylomeDB:   Q9KWZ1
- ProtClustDB:   PRK09375
- BioCyc:   BSUB:BSU27850-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00569
- InterPro:   IPR003473
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 41493; Mature: 41362

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: BINDING 46-46 BINDING 63-63 BINDING 141-141 BINDING 162-162 BINDING 256-256 BINDING 273-273

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILDVIKQSNDMMPESYKELSRKDMETRVAAIKKKFGSRLFIPGHHYQKDEVIQFADQT
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHCC
GDSLQLAQVAEKNKEADYIVFCGVHFMAETADMLTSEQQTVVLPDMRAGCSMADMADMQQ
CCCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHH
TNRAWKKLQHIFGDTIIPLTYVNSTAEIKAFVGKHGGATVTSSNAKKVLEWAFTQKKRIL
HHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCEEE
FLPDQHLGRNTAYDLGIALEDMAVWDPMKDELVAESGHTNVKVILWKGHCSVHEKFTTKN
ECCCHHCCCCCCEECCEEEHHHHHCCCCHHHHHHCCCCCEEEEEEEECCCCHHHHHHHCC
IHDMRERDPDIQIIVHPECSHEVVTLSDDNGSTKYIIDTINQAPAGSKWAIGTEMNLVQR
HHHHHHCCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEECCHHHHHHH
IIHEHPDKQIESLNPDMCPCLTMNRIDLPHLLWSLEQIEKGEPSGVIKVPKAIQEDALLA
HHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHH
LNRMLSIT
HHHHHCCC
>Mature Secondary Structure 
SILDVIKQSNDMMPESYKELSRKDMETRVAAIKKKFGSRLFIPGHHYQKDEVIQFADQT
CHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHCC
GDSLQLAQVAEKNKEADYIVFCGVHFMAETADMLTSEQQTVVLPDMRAGCSMADMADMQQ
CCCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHH
TNRAWKKLQHIFGDTIIPLTYVNSTAEIKAFVGKHGGATVTSSNAKKVLEWAFTQKKRIL
HHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCEEE
FLPDQHLGRNTAYDLGIALEDMAVWDPMKDELVAESGHTNVKVILWKGHCSVHEKFTTKN
ECCCHHCCCCCCEECCEEEHHHHHCCCCHHHHHHCCCCCEEEEEEEECCCCHHHHHHHCC
IHDMRERDPDIQIIVHPECSHEVVTLSDDNGSTKYIIDTINQAPAGSKWAIGTEMNLVQR
HHHHHHCCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEECCHHHHHHH
IIHEHPDKQIESLNPDMCPCLTMNRIDLPHLLWSLEQIEKGEPSGVIKVPKAIQEDALLA
HHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHH
LNRMLSIT
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377