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The map label for this gene is gpr

Identifier: 16079608

GI number: 16079608

Start: 2634505

End: 2635611

Strand: Reverse

Name: gpr

Synonym: BSU25540

Alternate gene names: 16079608

Gene position: 2635611-2634505 (Counterclockwise)

Preceding gene: 16079610

Following gene: 16079607

Centisome position: 62.52

GC content: 46.07

Gene sequence:

>1107_bases
ATGAAAAAGAGTGAGCTGGATGTGAATCAGTATTTGATACGGACCGATTTGGCAGTGGAAACGAAGGAAGCAATGGCCAA
TCAGCAGGCTGTGCCGACAAAAGAAATTAAAGGCTTTATTGAAAAAGAGCGTGATCACGGCGGCATTAAAATCCGCACAG
TTGATGTTACAAAGGAAGGCGCAGAGCTTTCGGGAAAAAAAGAAGGGCGCTATTTAACGCTTGAAGCACAGGGAATCAGG
GAGAATGATTCGGAAATGCAGGAGAAGGTCTCTGCTGTCTTTGCGGAGGAATTCTCAGCTTTTCTTGAAAACCTTAATAT
CTCAAAAGATGCGAGCTGTTTGATCGTTGGGCTCGGCAACTGGAACGTGACACCTGATGCGCTTGGACCGATGGCAGTAG
AAAATCTGTTGGTAACAAGGCACTTGTTTAAGCTTCAGCCGGAAAACGTACAGGAGGGTTACAGGCCTGTCAGTGCTTTT
GCACCGGGTGTAATGGGGATAACAGGAATCGAAACAAGTGACATTATTAAAGGTGTGATTGAGCAATCGAAGCCTGATTT
TGTCATCGCCATTGATGCGTTGGCGGCGCGGGCGGTGGAAAGGGTCAACACAACCATTCAAATATCGGATACAGGCATTC
ACCCGGGGTCTGGAGTGGGGAATAAACGAAAAGATTTAAGCAAAGACACGCTTGGTGTTCCGGTGATTGCTATCGGTGTT
CCGACAGTAGTTGATGCCGTGACAATTGCCAGCGACACGGTGGACTACATATTAAAACATTTTGGCAGAGAAATGAAGGA
TAACAGGCCATCAAGATCGCTTGTTCCGGCAGGCATGACGTTTGGGAAAAAGAAAGTGCTCACTGAAGACGATCTTCCCG
ATCAAAAGCAGCGCCAATCGTTCCTAGGTATTGTCGGAACCCTTCAAGAAGATGAAAAACGGCAGCTCATTCACGAGGTG
CTTTCGCCTTTAGGGCACAACTTAATGGTTACACCGAAGGAAGTCGATTCATTTATCGACGATATGGCAAATGTTTTAGC
GAACGGATTAAACACAGCGCTTCATGAAAAAGTGTCACAAGAAAACAAAGGCTCCTACAATCACTAA

Upstream 100 bases:

>100_bases
ATATAAATGTAAAGTATTTTTCATTGAAGGTTCTCTTTTTAGCATGATTTATTCAGCAAATGGCAACAATATAGGTACTT
AATGTGAAGGAGGCCCCTGT

Downstream 100 bases:

>100_bases
ACAGTTCTACTTCCTCTAGCTTGTTCATAGAGTAATTACTAGACAAGCGCTGGAGGGATTCAATGAGAAATAAACGCAGA
AACAGACAGATTGTTGTTGC

Product: germination protease

Products: NA

Alternate protein names: GPR endopeptidase; Germination proteinase; Spore protease

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKKSELDVNQYLIRTDLAVETKEAMANQQAVPTKEIKGFIEKERDHGGIKIRTVDVTKEGAELSGKKEGRYLTLEAQGIR
ENDSEMQEKVSAVFAEEFSAFLENLNISKDASCLIVGLGNWNVTPDALGPMAVENLLVTRHLFKLQPENVQEGYRPVSAF
APGVMGITGIETSDIIKGVIEQSKPDFVIAIDALAARAVERVNTTIQISDTGIHPGSGVGNKRKDLSKDTLGVPVIAIGV
PTVVDAVTIASDTVDYILKHFGREMKDNRPSRSLVPAGMTFGKKKVLTEDDLPDQKQRQSFLGIVGTLQEDEKRQLIHEV
LSPLGHNLMVTPKEVDSFIDDMANVLANGLNTALHEKVSQENKGSYNH

Sequences:

>Translated_368_residues
MKKSELDVNQYLIRTDLAVETKEAMANQQAVPTKEIKGFIEKERDHGGIKIRTVDVTKEGAELSGKKEGRYLTLEAQGIR
ENDSEMQEKVSAVFAEEFSAFLENLNISKDASCLIVGLGNWNVTPDALGPMAVENLLVTRHLFKLQPENVQEGYRPVSAF
APGVMGITGIETSDIIKGVIEQSKPDFVIAIDALAARAVERVNTTIQISDTGIHPGSGVGNKRKDLSKDTLGVPVIAIGV
PTVVDAVTIASDTVDYILKHFGREMKDNRPSRSLVPAGMTFGKKKVLTEDDLPDQKQRQSFLGIVGTLQEDEKRQLIHEV
LSPLGHNLMVTPKEVDSFIDDMANVLANGLNTALHEKVSQENKGSYNH
>Mature_368_residues
MKKSELDVNQYLIRTDLAVETKEAMANQQAVPTKEIKGFIEKERDHGGIKIRTVDVTKEGAELSGKKEGRYLTLEAQGIR
ENDSEMQEKVSAVFAEEFSAFLENLNISKDASCLIVGLGNWNVTPDALGPMAVENLLVTRHLFKLQPENVQEGYRPVSAF
APGVMGITGIETSDIIKGVIEQSKPDFVIAIDALAARAVERVNTTIQISDTGIHPGSGVGNKRKDLSKDTLGVPVIAIGV
PTVVDAVTIASDTVDYILKHFGREMKDNRPSRSLVPAGMTFGKKKVLTEDDLPDQKQRQSFLGIVGTLQEDEKRQLIHEV
LSPLGHNLMVTPKEVDSFIDDMANVLANGLNTALHEKVSQENKGSYNH

Specific function: Initiates the degradation of small, acid-soluble proteins during spore germination

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A25 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPR_BACSU (P22322)

Other databases:

- EMBL:   M55263
- EMBL:   D84432
- EMBL:   AL009126
- EMBL:   D17650
- PIR:   B39198
- RefSeq:   NP_390432.1
- ProteinModelPortal:   P22322
- SMR:   P22322
- MEROPS:   A25.001
- EnsemblBacteria:   EBBACT00000002436
- GeneID:   937838
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU25540
- NMPDR:   fig|224308.1.peg.2557
- GenoList:   BSU25540
- GeneTree:   EBGT00050000001716
- HOGENOM:   HBG304865
- OMA:   LMVTRHL
- ProtClustDB:   PRK02858
- BioCyc:   BSUB:BSU25540-MONOMER
- BRENDA:   3.4.24.78
- GO:   GO:0006508
- HAMAP:   MF_00626
- InterPro:   IPR005080
- InterPro:   IPR000671
- Gene3D:   G3DSA:3.40.50.1450
- PIRSF:   PIRSF019549
- ProDom:   PD041835
- TIGRFAMs:   TIGR01441

Pfam domain/function: PF03418 Peptidase_A25

EC number: =3.4.24.78

Molecular weight: Translated: 40283; Mature: 40283

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSELDVNQYLIRTDLAVETKEAMANQQAVPTKEIKGFIEKERDHGGIKIRTVDVTKEG
CCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCC
AELSGKKEGRYLTLEAQGIRENDSEMQEKVSAVFAEEFSAFLENLNISKDASCLIVGLGN
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
WNVTPDALGPMAVENLLVTRHLFKLQPENVQEGYRPVSAFAPGVMGITGIETSDIIKGVI
CCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHCCCCCEECCCCHHHHHHHHH
EQSKPDFVIAIDALAARAVERVNTTIQISDTGIHPGSGVGNKRKDLSKDTLGVPVIAIGV
HCCCCCEEEEHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCCEEEECH
PTVVDAVTIASDTVDYILKHFGREMKDNRPSRSLVPAGMTFGKKKVLTEDDLPDQKQRQS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FLGIVGTLQEDEKRQLIHEVLSPLGHNLMVTPKEVDSFIDDMANVLANGLNTALHEKVSQ
HHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENKGSYNH
CCCCCCCC
>Mature Secondary Structure
MKKSELDVNQYLIRTDLAVETKEAMANQQAVPTKEIKGFIEKERDHGGIKIRTVDVTKEG
CCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCC
AELSGKKEGRYLTLEAQGIRENDSEMQEKVSAVFAEEFSAFLENLNISKDASCLIVGLGN
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
WNVTPDALGPMAVENLLVTRHLFKLQPENVQEGYRPVSAFAPGVMGITGIETSDIIKGVI
CCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHCCCCCEECCCCHHHHHHHHH
EQSKPDFVIAIDALAARAVERVNTTIQISDTGIHPGSGVGNKRKDLSKDTLGVPVIAIGV
HCCCCCEEEEHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCCEEEECH
PTVVDAVTIASDTVDYILKHFGREMKDNRPSRSLVPAGMTFGKKKVLTEDDLPDQKQRQS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FLGIVGTLQEDEKRQLIHEVLSPLGHNLMVTPKEVDSFIDDMANVLANGLNTALHEKVSQ
HHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENKGSYNH
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1840582; 8969508; 9384377