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The map label for this gene is ccpN

Identifier: 16079579

GI number: 16079579

Start: 2604959

End: 2605597

Strand: Reverse

Name: ccpN

Synonym: BSU25250

Alternate gene names: 16079579

Gene position: 2605597-2604959 (Counterclockwise)

Preceding gene: 255767576

Following gene: 16079578

Centisome position: 61.81

GC content: 44.44

Gene sequence:

>639_bases
GTGAGTACGATCGAACTAAATAAACGGCAAGAACATATTTTGCAGATTGTAAAAGAAAACGGGCCGATTACAGGGGAGCA
TATTGCAGAAAAGCTGAACCTAACCAGGGCGACATTGCGCCCGGATTTAGCCATACTCACCATGTCAGGATTCCTCGAGG
CGCGCCCGAGAGTCGGTTATTTCTATACGGGAAAAACCGGCACACAGCTTTTGGCGGATAAACTCAAAAAGCTTCAGGTG
AAAGACTTTCAATCTATCCCCGTAGTGATTCACGAAAACGTTTCTGTGTACGATGCGATTTGCACCATGTTTTTAGAAGA
TGTAGGTACTCTGTTTGTGGTGGACCGCGATGCTGTTTTAGTCGGGGTGCTTTCACGAAAAGACTTGCTCAGAGCGAGCA
TTGGCCAGCAGGAGCTTACATCGGTCCCTGTTCACATCATCATGACAAGGATGCCGAACATTACGGTGTGCAGACGCGAG
GATTATGTGATGGACATTGCAAAGCACTTAATAGAAAAACAAATTGATGCACTGCCTGTCATCAAAGACACCGATAAAGG
CTTTGAAGTGATCGGCAGAGTGACAAAAACAAATATGACCAAAATACTTGTCAGTTTATCTGAAAATGAAATCCTATAA

Upstream 100 bases:

>100_bases
ATCGTCTTTTCCCCATTTATAAGTTTTTTGTTTGATTACAAGATATTTACGTTATAATATGGATTGTTATTTCTTTACAT
AGCTATGAAGTGAAAAGGTG

Downstream 100 bases:

>100_bases
GATTGCAAACTAACGGGGGGATAATATGAATAACCGCATCATCTATGTTGTATCGGATTCCGTCGGTGAAACGGCTGAAT
TGGTAGTAAAAGCAGCACTC

Product: negative regulator of gluconeogenesis

Products: NA

Alternate protein names: Catabolite control protein N; Control catabolite protein of gluconeogenesis

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSTIELNKRQEHILQIVKENGPITGEHIAEKLNLTRATLRPDLAILTMSGFLEARPRVGYFYTGKTGTQLLADKLKKLQV
KDFQSIPVVIHENVSVYDAICTMFLEDVGTLFVVDRDAVLVGVLSRKDLLRASIGQQELTSVPVHIIMTRMPNITVCRRE
DYVMDIAKHLIEKQIDALPVIKDTDKGFEVIGRVTKTNMTKILVSLSENEIL

Sequences:

>Translated_212_residues
MSTIELNKRQEHILQIVKENGPITGEHIAEKLNLTRATLRPDLAILTMSGFLEARPRVGYFYTGKTGTQLLADKLKKLQV
KDFQSIPVVIHENVSVYDAICTMFLEDVGTLFVVDRDAVLVGVLSRKDLLRASIGQQELTSVPVHIIMTRMPNITVCRRE
DYVMDIAKHLIEKQIDALPVIKDTDKGFEVIGRVTKTNMTKILVSLSENEIL
>Mature_211_residues
STIELNKRQEHILQIVKENGPITGEHIAEKLNLTRATLRPDLAILTMSGFLEARPRVGYFYTGKTGTQLLADKLKKLQVK
DFQSIPVVIHENVSVYDAICTMFLEDVGTLFVVDRDAVLVGVLSRKDLLRASIGQQELTSVPVHIIMTRMPNITVCRRED
YVMDIAKHLIEKQIDALPVIKDTDKGFEVIGRVTKTNMTKILVSLSENEIL

Specific function: Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCPN_BACSU (O34994)

Other databases:

- EMBL:   AL009126
- PIR:   A69969
- RefSeq:   NP_390403.1
- PDB:   3FV6
- PDB:   3FWR
- PDB:   3FWS
- PDBsum:   3FV6
- PDBsum:   3FWR
- PDBsum:   3FWS
- ProteinModelPortal:   O34994
- EnsemblBacteria:   EBBACT00000002373
- GeneID:   937886
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU25250
- NMPDR:   fig|224308.1.peg.2528
- GenoList:   BSU25250
- GeneTree:   EBGT00050000002018
- HOGENOM:   HBG304856
- OMA:   KENGPIT
- ProtClustDB:   CLSK873004
- BioCyc:   BSUB:BSU25250-MONOMER
- GO:   GO:0005622
- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR013196
- InterPro:   IPR001034
- InterPro:   IPR016842
- InterPro:   IPR011991
- Gene3D:   G3DSA:3.20.20.70
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF026546
- SMART:   SM00116
- SMART:   SM00420

Pfam domain/function: PF00571 CBS; PF08279 HTH_11

EC number: NA

Molecular weight: Translated: 23870; Mature: 23739

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS51371 CBS; PS00894 HTH_DEOR_1; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIELNKRQEHILQIVKENGPITGEHIAEKLNLTRATLRPDLAILTMSGFLEARPRVGY
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCE
FYTGKTGTQLLADKLKKLQVKDFQSIPVVIHENVSVYDAICTMFLEDVGTLFVVDRDAVL
EEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCEEEEEECCEEE
VGVLSRKDLLRASIGQQELTSVPVHIIMTRMPNITVCRREDYVMDIAKHLIEKQIDALPV
EEHHHHHHHHHHHCCHHHHHHCCHHHEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
IKDTDKGFEVIGRVTKTNMTKILVSLSENEIL
CCCCCCHHHHHHHHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure 
STIELNKRQEHILQIVKENGPITGEHIAEKLNLTRATLRPDLAILTMSGFLEARPRVGY
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCE
FYTGKTGTQLLADKLKKLQVKDFQSIPVVIHENVSVYDAICTMFLEDVGTLFVVDRDAVL
EEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCEEEEEECCEEE
VGVLSRKDLLRASIGQQELTSVPVHIIMTRMPNITVCRREDYVMDIAKHLIEKQIDALPV
EEHHHHHHHHHHHCCHHHHHHCCHHHEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
IKDTDKGFEVIGRVTKTNMTKILVSLSENEIL
CCCCCCHHHHHHHHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377