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The map label for this gene is comGB

Identifier: 16079528

GI number: 16079528

Start: 2557983

End: 2558954

Strand: Reverse

Name: comGB

Synonym: BSU24720

Alternate gene names: 16079528

Gene position: 2558954-2557983 (Counterclockwise)

Preceding gene: 16079529

Following gene: 16079527

Centisome position: 60.7

GC content: 41.67

Gene sequence:

>972_bases
ATGACTGCGGGCGGATATACACTTCTGGATGGATTACGCCTGATGGAACTTCAGATGAATAAGAGGCAGGCGGCTGACTT
GACTGATTCGGTCACTTGTTTGAGGGAAGGGGCTCCGTTTTATCAAGTACTAAAGAGTTTGTCATTTCATAAGGAAGCCG
TAGGTATTTGTTATTTTGCTGAAACACATGGTGAACTGCCTGCTTCAATGATCCAGAGCGGAGAGCTGCTGGAACGAAAA
ATTGCACAGGCAGACCAGCTGAAAAGAGTGCTGCGCTATCCGCTTTTCCTCATCTTTACGGTCGCTGTCATGTTTTATAT
GTTACAGTCCATCATCATTCCTCAGTTTTCCGGTATCTATCAATCGATGAATATGGAAACCTCACGTTCAACCGATATGC
TTTTTGCTTTTTTTCAGCATATTGATCTTGTGATCATTTTGCTTGTTCTTTTTACAGCAGGTATCGGGATTTATTATTGG
CTTGTGTTTAAGAAAAAATCACCTGCCCGGCAAATGCTGATTTGTATCAGGATTCCTTTGGTTGGAAAGCTTGTAAAGCT
GTTTAACAGCTACTTTTTTTCTTTGCAGCTAAGCAGCCTTTTAAAATCAGGCCTCTCAATTTATGACAGCCTTAATGCAT
TTAAACATCAAACGTTTCTCCCTTTCTACCGCTGCGAGGCTGAACAATTGATTGAACGGCTAAAAGCCGGTGAGTCAATT
GAATCCGCTATTTGTGGAAGCCTTTTTTATGAAACTGATTTATCAAAAGTCATATCTCACGGCCAGCTGAGCGGCCGATT
GGATCGGGAGCTTTTCACATACAGCCAATTCATATTACAGCGGCTGGAACACAAAGCGCAAAAATGGACAGGCATCCTTC
AGCCAATGATTTATGGATTTGTTGCAGCGATGATCTTACTTGTGTATTTATCTATGCTTGTGCCTATGTATCAGATGATG
AATCAAATGTGA

Upstream 100 bases:

>100_bases
TTAACGACAAACAACTATGACCGGTGGGTTTATCATGAAAAAGATTAGAAAAGTCTGGTTGTTAAAGGATCAAGCCAGGT
TATTAAAGAGGCTCGGTGAA

Downstream 100 bases:

>100_bases
AAGGAAGAGGCTGATGAATGAGAAAGGATTTACACTTGTTGAAATGTTAATCGTGCTCTTTATTATTTCGATTTTGCTTT
TAATTACGATACCGAACGTC

Product: membrane platform component of the DNA transport machinery

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTAGGYTLLDGLRLMELQMNKRQAADLTDSVTCLREGAPFYQVLKSLSFHKEAVGICYFAETHGELPASMIQSGELLERK
IAQADQLKRVLRYPLFLIFTVAVMFYMLQSIIIPQFSGIYQSMNMETSRSTDMLFAFFQHIDLVIILLVLFTAGIGIYYW
LVFKKKSPARQMLICIRIPLVGKLVKLFNSYFFSLQLSSLLKSGLSIYDSLNAFKHQTFLPFYRCEAEQLIERLKAGESI
ESAICGSLFYETDLSKVISHGQLSGRLDRELFTYSQFILQRLEHKAQKWTGILQPMIYGFVAAMILLVYLSMLVPMYQMM
NQM

Sequences:

>Translated_323_residues
MTAGGYTLLDGLRLMELQMNKRQAADLTDSVTCLREGAPFYQVLKSLSFHKEAVGICYFAETHGELPASMIQSGELLERK
IAQADQLKRVLRYPLFLIFTVAVMFYMLQSIIIPQFSGIYQSMNMETSRSTDMLFAFFQHIDLVIILLVLFTAGIGIYYW
LVFKKKSPARQMLICIRIPLVGKLVKLFNSYFFSLQLSSLLKSGLSIYDSLNAFKHQTFLPFYRCEAEQLIERLKAGESI
ESAICGSLFYETDLSKVISHGQLSGRLDRELFTYSQFILQRLEHKAQKWTGILQPMIYGFVAAMILLVYLSMLVPMYQMM
NQM
>Mature_322_residues
TAGGYTLLDGLRLMELQMNKRQAADLTDSVTCLREGAPFYQVLKSLSFHKEAVGICYFAETHGELPASMIQSGELLERKI
AQADQLKRVLRYPLFLIFTVAVMFYMLQSIIIPQFSGIYQSMNMETSRSTDMLFAFFQHIDLVIILLVLFTAGIGIYYWL
VFKKKSPARQMLICIRIPLVGKLVKLFNSYFFSLQLSSLLKSGLSIYDSLNAFKHQTFLPFYRCEAEQLIERLKAGESIE
SAICGSLFYETDLSKVISHGQLSGRLDRELFTYSQFILQRLEHKAQKWTGILQPMIYGFVAAMILLVYLSMLVPMYQMMN
QM

Specific function: Required for transformation and DNA binding

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COMGB_BACSU (P25954)

Other databases:

- EMBL:   M29691
- EMBL:   D84432
- EMBL:   AL009126
- PIR:   C30338
- RefSeq:   NP_390352.1
- ProteinModelPortal:   P25954
- EnsemblBacteria:   EBBACT00000002366
- GeneID:   938527
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU24720
- NMPDR:   fig|224308.1.peg.2476
- GenoList:   BSU24720
- GeneTree:   EBGT00050000002919
- HOGENOM:   HBG339913
- OMA:   IWERIET
- ProtClustDB:   CLSK887565
- BioCyc:   BSUB:BSU24720-MONOMER
- InterPro:   IPR018076
- InterPro:   IPR001992

Pfam domain/function: PF00482 GSPII_F

EC number: NA

Molecular weight: Translated: 37058; Mature: 36926

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1099c564)-; HASH(0x105f36c4)-; HASH(0x107dd0cc)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TAGGYTLLDGLRLMELQMNKRQAADLTDSVTCLREGAPFYQVLKSLSFHKEAVGICYFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEC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HHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590