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The map label for this gene is hepS

Identifier: 16079333

GI number: 16079333

Start: 2383615

End: 2384370

Strand: Reverse

Name: hepS

Synonym: BSU22760

Alternate gene names: 16079333

Gene position: 2384370-2383615 (Counterclockwise)

Preceding gene: 16079334

Following gene: 16079332

Centisome position: 56.56

GC content: 39.02

Gene sequence:

>756_bases
TTGCAAGACATCTACGGAACTTTAGCCAATCTGAACACGAAATTAAAACAAAAGCTGTCTCATCCTTATTTAGCGAAGCA
TATTTCTGCGCCGAAAATTGATGAGGATAAGCTTCTTCTTTTTCATGCTTTATTTGAAGAAGCCGACATAAAAAACAACG
ACAGAGAAAATTATATTGTAACAGCGATGCTTGTACAAAGCGCCCTTGATACCCATGATGAAGTGACGACAGCTAGAGTC
ATAAAACGAGACGAAAACAAAAACCGCCAATTGACTGTTCTCGCGGGCGATTATTTCAGCGGGCTGTACTACTCTTTACT
ATCTGAAATGAAGGATATCTACATGATTCGGACGCTTGCTACAGCCATTAAAGAAATCAACGAACATAAAATTCGTCTGT
ATGACCGTTCTTTCAAGGACGAAAACGATTTTTTCGAAAGTGTCGGCATCGTTGAATCAGCTTTATTCCATCGTGTGGCG
GAACACTTCAACCTCCCGCGCTGGAAAAAGCTGTCGAGTGATTTTTTTGTATTTAAGCGGCTTATGAACGGAAATGATGC
ATTTCTGGATGTGATCGGCAGTTTTATACAGCTGGGAAAAACAAAAGAAGAGATATTAGAAGATTGTTTTAAAAAAGCGA
AAAACAGCATTGAGTCACTTCTGCCTCTAAATTCACCTATTCAGAACATTTTAATAAACCGTCTGAAGACAATCAGCCAA
GATCAAACCTATCATCAGAAAGTGGAAGAAGGGTAA

Upstream 100 bases:

>100_bases
TTTTTTTATGCTATAATGATACCTGCGTAAGCGAATGAAAAGATAAAACTCATACATAGATTAAGAAATAAATGTGAATT
TGGGGACAAGGGTGATATTT

Downstream 100 bases:

>100_bases
ACCATTATGCAGGACTCAAAAGAACAGCGCGTACACGGAGTATTTGAAAAAATATATAAAAATTATGACCAAATGAACTC
TGTCATCAGTTTTCAGCAGC

Product: heptaprenyl diphosphate synthase component I

Products: NA

Alternate protein names: HEPPP synthase subunit 1; Spore germination protein C1

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MQDIYGTLANLNTKLKQKLSHPYLAKHISAPKIDEDKLLLFHALFEEADIKNNDRENYIVTAMLVQSALDTHDEVTTARV
IKRDENKNRQLTVLAGDYFSGLYYSLLSEMKDIYMIRTLATAIKEINEHKIRLYDRSFKDENDFFESVGIVESALFHRVA
EHFNLPRWKKLSSDFFVFKRLMNGNDAFLDVIGSFIQLGKTKEEILEDCFKKAKNSIESLLPLNSPIQNILINRLKTISQ
DQTYHQKVEEG

Sequences:

>Translated_251_residues
MQDIYGTLANLNTKLKQKLSHPYLAKHISAPKIDEDKLLLFHALFEEADIKNNDRENYIVTAMLVQSALDTHDEVTTARV
IKRDENKNRQLTVLAGDYFSGLYYSLLSEMKDIYMIRTLATAIKEINEHKIRLYDRSFKDENDFFESVGIVESALFHRVA
EHFNLPRWKKLSSDFFVFKRLMNGNDAFLDVIGSFIQLGKTKEEILEDCFKKAKNSIESLLPLNSPIQNILINRLKTISQ
DQTYHQKVEEG
>Mature_251_residues
MQDIYGTLANLNTKLKQKLSHPYLAKHISAPKIDEDKLLLFHALFEEADIKNNDRENYIVTAMLVQSALDTHDEVTTARV
IKRDENKNRQLTVLAGDYFSGLYYSLLSEMKDIYMIRTLATAIKEINEHKIRLYDRSFKDENDFFESVGIVESALFHRVA
EHFNLPRWKKLSSDFFVFKRLMNGNDAFLDVIGSFIQLGKTKEEILEDCFKKAKNSIESLLPLNSPIQNILINRLKTISQ
DQTYHQKVEEG

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HEPS1_BACSU (P31112)

Other databases:

- EMBL:   M80245
- EMBL:   AL009126
- PIR:   C69630
- RefSeq:   NP_390157.1
- ProteinModelPortal:   P31112
- EnsemblBacteria:   EBBACT00000003469
- GeneID:   938998
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU22760
- NMPDR:   fig|224308.1.peg.2280
- GenoList:   BSU22760
- GeneTree:   EBGT00050000001174
- HOGENOM:   HBG338135
- OMA:   FYSALYY
- ProtClustDB:   CLSK887500
- BioCyc:   BSUB:BSU22760-MONOMER
- BioCyc:   MetaCyc:MONOMER-13769
- BRENDA:   2.5.1.30
- InterPro:   IPR009920

Pfam domain/function: PF07307 HEPPP_synt_1

EC number: =2.5.1.30

Molecular weight: Translated: 29123; Mature: 29123

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDIYGTLANLNTKLKQKLSHPYLAKHISAPKIDEDKLLLFHALFEEADIKNNDRENYIV
CCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
TAMLVQSALDTHDEVTTARVIKRDENKNRQLTVLAGDYFSGLYYSLLSEMKDIYMIRTLA
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
TAIKEINEHKIRLYDRSFKDENDFFESVGIVESALFHRVAEHFNLPRWKKLSSDFFVFKR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LMNGNDAFLDVIGSFIQLGKTKEEILEDCFKKAKNSIESLLPLNSPIQNILINRLKTISQ
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
DQTYHQKVEEG
CHHHHHHHCCC
>Mature Secondary Structure
MQDIYGTLANLNTKLKQKLSHPYLAKHISAPKIDEDKLLLFHALFEEADIKNNDRENYIV
CCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
TAMLVQSALDTHDEVTTARVIKRDENKNRQLTVLAGDYFSGLYYSLLSEMKDIYMIRTLA
HHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
TAIKEINEHKIRLYDRSFKDENDFFESVGIVESALFHRVAEHFNLPRWKKLSSDFFVFKR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LMNGNDAFLDVIGSFIQLGKTKEEILEDCFKKAKNSIESLLPLNSPIQNILINRLKTISQ
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
DQTYHQKVEEG
CHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033