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The map label for this gene is ubiE

Identifier: 16079332

GI number: 16079332

Start: 2382907

End: 2383608

Strand: Reverse

Name: ubiE

Synonym: BSU22750

Alternate gene names: 16079332

Gene position: 2383608-2382907 (Counterclockwise)

Preceding gene: 16079333

Following gene: 16079331

Centisome position: 56.54

GC content: 45.44

Gene sequence:

>702_bases
ATGCAGGACTCAAAAGAACAGCGCGTACACGGAGTATTTGAAAAAATATATAAAAATTATGACCAAATGAACTCTGTCAT
CAGTTTTCAGCAGCATAAAAAATGGCGCGACAAAACGATGCGCATCATGAATGTAAAGGAAGGCGCAAAAGCACTTGATG
TCTGCTGCGGAACGGCTGACTGGACGATCGCTCTTGCAAAAGCGGCAGGCAAAAGCGGCGAGATCAAGGGCTTGGATTTC
AGTGAAAATATGCTGAGTGTCGGCGAGCAGAAAGTAAAAGACGGCGGATTCAGCCAAATTGAACTGCTGCACGGAAATGC
GATGGAGCTTCCTTTTGATGATGATACATTTGATTATGTCACCATTGGCTTCGGACTCCGCAATGTCCCTGATTACTTGA
CTGTACTGAAAGAGATGAGACGTGTAGTGAAGCCGGGCGGGCAGGTGGTATGTCTGGAAACGTCCCAGCCGGAAATGTTC
GGATTCAGACAGGCTTACTTTATGTACTTTAAGTATATTATGCCGTTTTTCGGGAAACTGTTTGCGAAGAGCTATAAAGA
ATATTCTTGGCTTCAAGAATCAGCCAGAGATTTCCCTGGAATGAAGGAACTGGCAGGCCTGTTTGAAGAGGCGGGCCTGA
AAAATGTTAAATATCATTCGTTTACTGGCGGAGTCGCTGCCACGCATATCGGATGGAAATGA

Upstream 100 bases:

>100_bases
GCCTCTAAATTCACCTATTCAGAACATTTTAATAAACCGTCTGAAGACAATCAGCCAAGATCAAACCTATCATCAGAAAG
TGGAAGAAGGGTAAACCATT

Downstream 100 bases:

>100_bases
AAACACAGATGTTTGGGTGAATGATATGAAATTTAAAATGGCCTACTCTTTTTTAAATGACGATATTGATGTAATCGAAA
GAGAACTTGAACAAACCGTA

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MQDSKEQRVHGVFEKIYKNYDQMNSVISFQQHKKWRDKTMRIMNVKEGAKALDVCCGTADWTIALAKAAGKSGEIKGLDF
SENMLSVGEQKVKDGGFSQIELLHGNAMELPFDDDTFDYVTIGFGLRNVPDYLTVLKEMRRVVKPGGQVVCLETSQPEMF
GFRQAYFMYFKYIMPFFGKLFAKSYKEYSWLQESARDFPGMKELAGLFEEAGLKNVKYHSFTGGVAATHIGWK

Sequences:

>Translated_233_residues
MQDSKEQRVHGVFEKIYKNYDQMNSVISFQQHKKWRDKTMRIMNVKEGAKALDVCCGTADWTIALAKAAGKSGEIKGLDF
SENMLSVGEQKVKDGGFSQIELLHGNAMELPFDDDTFDYVTIGFGLRNVPDYLTVLKEMRRVVKPGGQVVCLETSQPEMF
GFRQAYFMYFKYIMPFFGKLFAKSYKEYSWLQESARDFPGMKELAGLFEEAGLKNVKYHSFTGGVAATHIGWK
>Mature_233_residues
MQDSKEQRVHGVFEKIYKNYDQMNSVISFQQHKKWRDKTMRIMNVKEGAKALDVCCGTADWTIALAKAAGKSGEIKGLDF
SENMLSVGEQKVKDGGFSQIELLHGNAMELPFDDDTFDYVTIGFGLRNVPDYLTVLKEMRRVVKPGGQVVCLETSQPEMF
GFRQAYFMYFKYIMPFFGKLFAKSYKEYSWLQESARDFPGMKELAGLFEEAGLKNVKYHSFTGGVAATHIGWK

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI116063536, Length=266, Percent_Identity=33.4586466165414, Blast_Score=146, Evalue=2e-35,
Organism=Escherichia coli, GI48994983, Length=234, Percent_Identity=37.6068376068376, Blast_Score=171, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17557039, Length=232, Percent_Identity=34.9137931034483, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6323526, Length=249, Percent_Identity=30.5220883534137, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24641702, Length=246, Percent_Identity=32.520325203252, Blast_Score=140, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014122
- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 26577; Mature: 26577

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS01183 UBIE_1 ; PS01184 UBIE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDSKEQRVHGVFEKIYKNYDQMNSVISFQQHKKWRDKTMRIMNVKEGAKALDVCCGTAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
WTIALAKAAGKSGEIKGLDFSENMLSVGEQKVKDGGFSQIELLHGNAMELPFDDDTFDYV
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCCCCCEE
TIGFGLRNVPDYLTVLKEMRRVVKPGGQVVCLETSQPEMFGFRQAYFMYFKYIMPFFGKL
EECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
FAKSYKEYSWLQESARDFPGMKELAGLFEEAGLKNVKYHSFTGGVAATHIGWK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHCCCCC
>Mature Secondary Structure
MQDSKEQRVHGVFEKIYKNYDQMNSVISFQQHKKWRDKTMRIMNVKEGAKALDVCCGTAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
WTIALAKAAGKSGEIKGLDFSENMLSVGEQKVKDGGFSQIELLHGNAMELPFDDDTFDYV
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCCCCCEE
TIGFGLRNVPDYLTVLKEMRRVVKPGGQVVCLETSQPEMFGFRQAYFMYFKYIMPFFGKL
EECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
FAKSYKEYSWLQESARDFPGMKELAGLFEEAGLKNVKYHSFTGGVAATHIGWK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA