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The map label for this gene is tyrA

Identifier: 16079318

GI number: 16079318

Start: 2369251

End: 2370366

Strand: Reverse

Name: tyrA

Synonym: BSU22610

Alternate gene names: 16079318

Gene position: 2370366-2369251 (Counterclockwise)

Preceding gene: 255767486

Following gene: 16079317

Centisome position: 56.23

GC content: 44.35

Gene sequence:

>1116_bases
ATGAATCAAATGAAAGATACAATATTGCTCGCCGGTCTCGGATTGATAGGCGGTTCGATTGCCCTAGCCATCAAAAAAAA
TCATCCCGGCAAACGGATTATCGGAATCGACATCTCTGATGAACAGGCGGTAGCGGCATTAAAATTAGGCGTGATAGACG
ATCGTGCTGATTCGTTTATTAGCGGTGTGAAAGAGGCAGCTACAGTAATCATTGCGACACCTGTTGAACAAACACTGGTT
ATGCTTGAAGAGCTGGCTCATTCAGGAATTGAACATGAGCTTTTGATTACGGATGTAGGAAGCACAAAGCAAAAAGTGGT
TGATTACGCTGATCAAGTGCTGCCTAGCCGCTATCAATTTGTCGGAGGGCATCCGATGGCGGGTTCACATAAATCAGGAG
TGGCCGCTGCGAAGGAGTTCCTGTTTGAAAATGCATTTTATATTTTAACGCCAGGCCAGAAAACGGACAAACAAGCTGTG
GAACAGTTAAAAAACCTGCTGAAGGGGACGAATGCCCATTTTGTGGAAATGTCGCCAGAGGAGCATGATGGCGTTACAAG
CGTAATCAGTCATTTTCCGCATATTGTAGCAGCTAGCCTTGTTCACCAAACCCATCATTCGGAAAACCTGTATCCGCTTG
TTAAGCGTTTTGCTGCCGGCGGGTTCAGAGATATTACAAGGATTGCATCAAGCAGCCCGGCAATGTGGCGGGATATTTTA
TTACATAATAAAGATAAAATCTTAGACCGTTTTGATGAGTGGATTCGTGAAATTGACAAGATCCGTACATATGTAGAACA
AGAAGATGCGGAAAATCTATTTCGTTATTTTAAAACAGCCAAGGATTATCGCGACGGGCTGCCGCTTCGGCAGAAGGGAG
CGATACCTGCATTTTATGATTTATATGTGGATGTACCCGATCATCCGGGTGTAATATCCGAGATAACAGCGATCTTAGCT
GCGGAGCGCATCAGTATCACGAATATCCGCATTATCGAAACACGAGAGGATATTAACGGGATTTTAAGGATCAGTTTTCA
GTCTGATGACGACCGCAAAAGGGCAGAACAATGCATTGAAGCCCGGGCGGAATATGAAACTTTTTATGCTGATTGA

Upstream 100 bases:

>100_bases
AACAAAAGAGCAAAATGAAGAAATACTTGCCATTTTAGCTGAAATTTTATAAGAGGTGATCAAATATCACCTCTTTAGTC
TATAAACCAGGTGATGACGT

Downstream 100 bases:

>100_bases
GGTGGAAAAAATGAAACGAGATAAGGTGCAGACCTTACATGGAGAAATACATATTCCCGGTGATAAATCCATTTCTCACC
GCTCTGTTATGTTTGGCGCG

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MNQMKDTILLAGLGLIGGSIALAIKKNHPGKRIIGIDISDEQAVAALKLGVIDDRADSFISGVKEAATVIIATPVEQTLV
MLEELAHSGIEHELLITDVGSTKQKVVDYADQVLPSRYQFVGGHPMAGSHKSGVAAAKEFLFENAFYILTPGQKTDKQAV
EQLKNLLKGTNAHFVEMSPEEHDGVTSVISHFPHIVAASLVHQTHHSENLYPLVKRFAAGGFRDITRIASSSPAMWRDIL
LHNKDKILDRFDEWIREIDKIRTYVEQEDAENLFRYFKTAKDYRDGLPLRQKGAIPAFYDLYVDVPDHPGVISEITAILA
AERISITNIRIIETREDINGILRISFQSDDDRKRAEQCIEARAEYETFYAD

Sequences:

>Translated_371_residues
MNQMKDTILLAGLGLIGGSIALAIKKNHPGKRIIGIDISDEQAVAALKLGVIDDRADSFISGVKEAATVIIATPVEQTLV
MLEELAHSGIEHELLITDVGSTKQKVVDYADQVLPSRYQFVGGHPMAGSHKSGVAAAKEFLFENAFYILTPGQKTDKQAV
EQLKNLLKGTNAHFVEMSPEEHDGVTSVISHFPHIVAASLVHQTHHSENLYPLVKRFAAGGFRDITRIASSSPAMWRDIL
LHNKDKILDRFDEWIREIDKIRTYVEQEDAENLFRYFKTAKDYRDGLPLRQKGAIPAFYDLYVDVPDHPGVISEITAILA
AERISITNIRIIETREDINGILRISFQSDDDRKRAEQCIEARAEYETFYAD
>Mature_371_residues
MNQMKDTILLAGLGLIGGSIALAIKKNHPGKRIIGIDISDEQAVAALKLGVIDDRADSFISGVKEAATVIIATPVEQTLV
MLEELAHSGIEHELLITDVGSTKQKVVDYADQVLPSRYQFVGGHPMAGSHKSGVAAAKEFLFENAFYILTPGQKTDKQAV
EQLKNLLKGTNAHFVEMSPEEHDGVTSVISHFPHIVAASLVHQTHHSENLYPLVKRFAAGGFRDITRIASSSPAMWRDIL
LHNKDKILDRFDEWIREIDKIRTYVEQEDAENLFRYFKTAKDYRDGLPLRQKGAIPAFYDLYVDVPDHPGVISEITAILA
AERISITNIRIIETREDINGILRISFQSDDDRKRAEQCIEARAEYETFYAD

Specific function: Unknown

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TYRA_BACSU (P20692)

Other databases:

- EMBL:   M80245
- EMBL:   AL009126
- RefSeq:   NP_390142.1
- ProteinModelPortal:   P20692
- SMR:   P20692
- EnsemblBacteria:   EBBACT00000001911
- GeneID:   939013
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU22610
- NMPDR:   fig|224308.1.peg.2265
- GenoList:   BSU22610
- GeneTree:   EBGT00050000001617
- HOGENOM:   HBG544990
- OMA:   QRAIRWG
- ProtClustDB:   PRK06545
- BioCyc:   BSUB:BSU22610-MONOMER
- BRENDA:   1.3.1.12
- InterPro:   IPR008927
- InterPro:   IPR002912
- InterPro:   IPR016040
- InterPro:   IPR003099
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21363

Pfam domain/function: PF01842 ACT; PF02153 PDH; SSF48179 6DGDH_C_like

EC number: =1.3.1.12

Molecular weight: Translated: 41435; Mature: 41435

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS51176 PDH_ADH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQMKDTILLAGLGLIGGSIALAIKKNHPGKRIIGIDISDEQAVAALKLGVIDDRADSFI
CCCHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHCCCCCHHHHHH
SGVKEAATVIIATPVEQTLVMLEELAHSGIEHELLITDVGSTKQKVVDYADQVLPSRYQF
HHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHC
VGGHPMAGSHKSGVAAAKEFLFENAFYILTPGQKTDKQAVEQLKNLLKGTNAHFVEMSPE
CCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCC
EHDGVTSVISHFPHIVAASLVHQTHHSENLYPLVKRFAAGGFRDITRIASSSPAMWRDIL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHH
LHNKDKILDRFDEWIREIDKIRTYVEQEDAENLFRYFKTAKDYRDGLPLRQKGAIPAFYD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
LYVDVPDHPGVISEITAILAAERISITNIRIIETREDINGILRISFQSDDDRKRAEQCIE
EEEECCCCCCHHHHHHHHHHHHHEEEEEEEEEEEHHCCCEEEEEEECCCCHHHHHHHHHH
ARAEYETFYAD
HHHHHHHHCCC
>Mature Secondary Structure
MNQMKDTILLAGLGLIGGSIALAIKKNHPGKRIIGIDISDEQAVAALKLGVIDDRADSFI
CCCHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHCCCCCHHHHHH
SGVKEAATVIIATPVEQTLVMLEELAHSGIEHELLITDVGSTKQKVVDYADQVLPSRYQF
HHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHC
VGGHPMAGSHKSGVAAAKEFLFENAFYILTPGQKTDKQAVEQLKNLLKGTNAHFVEMSPE
CCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCC
EHDGVTSVISHFPHIVAASLVHQTHHSENLYPLVKRFAAGGFRDITRIASSSPAMWRDIL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHH
LHNKDKILDRFDEWIREIDKIRTYVEQEDAENLFRYFKTAKDYRDGLPLRQKGAIPAFYD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
LYVDVPDHPGVISEITAILAAERISITNIRIIETREDINGILRISFQSDDDRKRAEQCIE
EEEECCCCCCHHHHHHHHHHHHHEEEEEEEEEEEHHCCCEEEEEEECCCCHHHHHHHHHH
ARAEYETFYAD
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3106153; 9384377