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The map label for this gene is yprA

Identifier: 16079280

GI number: 16079280

Start: 2334581

End: 2336830

Strand: Reverse

Name: yprA

Synonym: BSU22220

Alternate gene names: 16079280

Gene position: 2336830-2334581 (Counterclockwise)

Preceding gene: 16079281

Following gene: 16079279

Centisome position: 55.43

GC content: 43.82

Gene sequence:

>2250_bases
ATGAAAAAGAAATCACTGACTGAACTCATTTCTGATTTAAAAGGAAATGAAAACGTTGTGAATTGGCATGAAATTGAGCC
TCGGGAAGCAAAAACAAGGCCTATGCCCGAAAGTATAGACGAGAGAATCAAAGCGGCCCTTTCGAAAAGGGGCATTGATG
AACTATATACTCACCAATATTCCGCTTTTCAATATGTGCAAAAAGGAGAGAGCATCGTTACCGTAACGCCAACAGCATCA
GGAAAAACGTTATGCTACAACCTCCCAGTCCTGCAGTCCATCGCCCAAGATGAAACAAACCGGGCGTTATATTTATTTCC
GACTAAAGCGCTGGCACAAGACCAAAAGAGCGAGCTAAATGAAATTATTGATGAAATGGGCATTGATATTAAAAGCTTTA
CATATGACGGGGATACGTCTCCGGCAATCAGACAAAAGGTGAGAAAAGCAGGTCATATTGTCATTACAAACCCCGATATG
CTGCATTCTGCCATTCTACCGCATCATACGAAATGGGTCAGTTTGTTTGAAAACCTTAAGTATATCGTCATCGATGAGCT
TCATACGTATCGAGGTGTGTTCGGCAGCCATGTGGCAAATGTGATCCGGCGGCTGAAGCGGATCTGCCGGTTTTATGGAA
GTGATCCAGTTTTTATTTGTACTTCCGCAACGATTGCCAACCCAAAGGAATTGGGAGAGCAGCTGACAGGCAAACCGATG
CGGCTGGTCGATGACAACGGCGCACCGAGCGGACGCAAGCATTTTGTGTTTTACAATCCGCCAATTGTGAACAAACCGCT
GAATATTAGAAGGAGCGCAACCGCAGAAGTGAATGAACTGGCGAAAGAGTTCCTTAAAAACAAAGTGCAGACCATTGTTT
TTGCCAGAAGCAGAGTTCGGGTGGAAATTATTTTAAGCCATATTCAGGAGCTTGTGAAAAAAGAGATTGGAACAAAATCA
ATCAGAGGCTATCGGGGAGGCTATCTGCCGAAAGAGCGAAGAGAAATCGAAAGAGGACTGAGAGAAGGCGACATTTTAGG
AGTGGTCAGTACGAATGCCTTAGAGCTTGGTGTTGATATCGGCCAGCTGCAAGTGTGTGTAATGACGGGGTATCCCGGAA
GTGTTGCAAGTGCTTGGCAGCAGGCGGGACGAGCCGGCAGAAGACACGGTGAATCTTTGATTATCATGGTAGCCAATTCA
ACACCGATTGACCAATATATTGTGCGGCATCCTGAATATTTCTTTAATCGTTCGCCGGAATCTGCAAGAATCAATCCGGA
GAATTTGATTATTTTAGTAGACCACTTAAAGTGTGCGGCTTATGAGCTTCCTTTTAGAGCTGATGAAGAATTTGGAGCCA
TGGAAGTCAGTGATATTCTTGAGTATCTTCAGGAAGAGGCTGTTCTTCACCGCAACGGCGAACGGTACCATTGGGCAAGT
GAGTCGTTCCCTGCGTCAAACATCAGTTTGCGTTCCGCCTCCCAGGAAAATGTCGTTATAGTTGATCAGTCGGATATTGC
AAATGTAAGGATTATCGGTGAAATGGACCGTTTTAGTGCGATGACGCTTTTGCATGATGAAGCGATTTATTTGCATGAAG
GCGTTCAGTATCAAGTTGAGAAGCTCGATTGGGACCATAAAAAGGCGTATGTCAGAAAAGTCGATGTCGAATATTATACG
GATGCAAACCTGGCAGTTCAGCTGAAGGTATTAGAAATCGATAAAACGAAAGAAAAAAGCCGTACGTCATTGCACTACGG
AGACGTCACTGTCAATGCCCTGCCGACCATTTTTAAAAAAATAAAAATGACCACTTTTGAAAATATTGGGTCTGGACCTA
TTCATTTGCCGGAAGAAGAACTGCATACAAGTGCAGCTTGGCTCGAAATCAAAACAGCGGATGAAGACATCGGGGAAAAG
ACACTGGAACAGCTGCTTCTTGGCATCTCGAATGTGCTGCAGCATATTGTCCCTGTGTATATCATGTGTGATCGAAATGA
TGTTCATGTTGTTTCTCAAATTAAAGCAGCCCATACCGGATTGCCAACCATATTTTTATATGATCATTATCCGGGCGGTA
TCGGTTTGGCGGAGGAAGTCTTTAAACGTTTTTCAGACATTAATGAAGCGGCGAAACAACTGATTACACATTGTCCTTGT
CATGACGGCTGTCCGTCTTGTATAGGTACGGAAATAGAAGGGATAAAAGCAAAGGAAAGAATTTTGCAGCTGTTGGATCA
AATGTCGTAA

Upstream 100 bases:

>100_bases
AGGGCGTATGCCTTGCTTTTTTTATTCAACTGTATAAAATTTGCACCTAGCCATGCAAACAAATATTCGGTAAACTGTAC
TTGACAAAGAGGTGTAAAGA

Downstream 100 bases:

>100_bases
GGAGGGAGGCCGGATATGTCATTAAAAGGGAAACTCCAACGGATGAAAAAGCACATGGCGCTCGACGAAGGAGAACAAAA
AATAGAAGCAGGCAAACAAG

Product: ATP-dependent helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MKKKSLTELISDLKGNENVVNWHEIEPREAKTRPMPESIDERIKAALSKRGIDELYTHQYSAFQYVQKGESIVTVTPTAS
GKTLCYNLPVLQSIAQDETNRALYLFPTKALAQDQKSELNEIIDEMGIDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDM
LHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLKRICRFYGSDPVFICTSATIANPKELGEQLTGKPM
RLVDDNGAPSGRKHFVFYNPPIVNKPLNIRRSATAEVNELAKEFLKNKVQTIVFARSRVRVEIILSHIQELVKKEIGTKS
IRGYRGGYLPKERREIERGLREGDILGVVSTNALELGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRRHGESLIIMVANS
TPIDQYIVRHPEYFFNRSPESARINPENLIILVDHLKCAAYELPFRADEEFGAMEVSDILEYLQEEAVLHRNGERYHWAS
ESFPASNISLRSASQENVVIVDQSDIANVRIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKAYVRKVDVEYYT
DANLAVQLKVLEIDKTKEKSRTSLHYGDVTVNALPTIFKKIKMTTFENIGSGPIHLPEEELHTSAAWLEIKTADEDIGEK
TLEQLLLGISNVLQHIVPVYIMCDRNDVHVVSQIKAAHTGLPTIFLYDHYPGGIGLAEEVFKRFSDINEAAKQLITHCPC
HDGCPSCIGTEIEGIKAKERILQLLDQMS

Sequences:

>Translated_749_residues
MKKKSLTELISDLKGNENVVNWHEIEPREAKTRPMPESIDERIKAALSKRGIDELYTHQYSAFQYVQKGESIVTVTPTAS
GKTLCYNLPVLQSIAQDETNRALYLFPTKALAQDQKSELNEIIDEMGIDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDM
LHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLKRICRFYGSDPVFICTSATIANPKELGEQLTGKPM
RLVDDNGAPSGRKHFVFYNPPIVNKPLNIRRSATAEVNELAKEFLKNKVQTIVFARSRVRVEIILSHIQELVKKEIGTKS
IRGYRGGYLPKERREIERGLREGDILGVVSTNALELGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRRHGESLIIMVANS
TPIDQYIVRHPEYFFNRSPESARINPENLIILVDHLKCAAYELPFRADEEFGAMEVSDILEYLQEEAVLHRNGERYHWAS
ESFPASNISLRSASQENVVIVDQSDIANVRIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKAYVRKVDVEYYT
DANLAVQLKVLEIDKTKEKSRTSLHYGDVTVNALPTIFKKIKMTTFENIGSGPIHLPEEELHTSAAWLEIKTADEDIGEK
TLEQLLLGISNVLQHIVPVYIMCDRNDVHVVSQIKAAHTGLPTIFLYDHYPGGIGLAEEVFKRFSDINEAAKQLITHCPC
HDGCPSCIGTEIEGIKAKERILQLLDQMS
>Mature_749_residues
MKKKSLTELISDLKGNENVVNWHEIEPREAKTRPMPESIDERIKAALSKRGIDELYTHQYSAFQYVQKGESIVTVTPTAS
GKTLCYNLPVLQSIAQDETNRALYLFPTKALAQDQKSELNEIIDEMGIDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDM
LHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLKRICRFYGSDPVFICTSATIANPKELGEQLTGKPM
RLVDDNGAPSGRKHFVFYNPPIVNKPLNIRRSATAEVNELAKEFLKNKVQTIVFARSRVRVEIILSHIQELVKKEIGTKS
IRGYRGGYLPKERREIERGLREGDILGVVSTNALELGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRRHGESLIIMVANS
TPIDQYIVRHPEYFFNRSPESARINPENLIILVDHLKCAAYELPFRADEEFGAMEVSDILEYLQEEAVLHRNGERYHWAS
ESFPASNISLRSASQENVVIVDQSDIANVRIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKAYVRKVDVEYYT
DANLAVQLKVLEIDKTKEKSRTSLHYGDVTVNALPTIFKKIKMTTFENIGSGPIHLPEEELHTSAAWLEIKTADEDIGEK
TLEQLLLGISNVLQHIVPVYIMCDRNDVHVVSQIKAAHTGLPTIFLYDHYPGGIGLAEEVFKRFSDINEAAKQLITHCPC
HDGCPSCIGTEIEGIKAKERILQLLDQMS

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain

Homologues:

Organism=Homo sapiens, GI188035877, Length=380, Percent_Identity=24.7368421052632, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320497, Length=709, Percent_Identity=32.2990126939351, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI9755332, Length=431, Percent_Identity=23.2018561484919, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YPRA_BACSU (P50830)

Other databases:

- EMBL:   L47838
- EMBL:   AL009126
- PIR:   B69941
- RefSeq:   NP_390104.1
- ProteinModelPortal:   P50830
- SMR:   P50830
- EnsemblBacteria:   EBBACT00000000215
- GeneID:   939052
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU22220
- NMPDR:   fig|224308.1.peg.2227
- GenoList:   BSU22220
- GeneTree:   EBGT00050000000884
- HOGENOM:   HBG402483
- OMA:   ALWEPPL
- PhylomeDB:   P50830
- ProtClustDB:   CLSK2484255
- BioCyc:   BSUB:BSU22220-MONOMER
- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- SMART:   SM00487
- SMART:   SM00490

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C

EC number: 3.6.1.- [C]

Molecular weight: Translated: 84591; Mature: 84591

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS51192 HELICASE_ATP_BIND_1; PS51194 HELICASE_CTER; PS00200 RIESKE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKSLTELISDLKGNENVVNWHEIEPREAKTRPMPESIDERIKAALSKRGIDELYTHQY
CCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
SAFQYVQKGESIVTVTPTASGKTLCYNLPVLQSIAQDETNRALYLFPTKALAQDQKSELN
HHHHHHHCCCEEEEEECCCCCCEEEEECHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHH
EIIDEMGIDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDMLHSAILPHHTKWVSLFENLK
HHHHHHCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCHHHHHHHCCCHHHHHHHHHCCC
YIVIDELHTYRGVFGSHVANVIRRLKRICRFYGSDPVFICTSATIANPKELGEQLTGKPM
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCE
RLVDDNGAPSGRKHFVFYNPPIVNKPLNIRRSATAEVNELAKEFLKNKVQTIVFARSRVR
EEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEIILSHIQELVKKEIGTKSIRGYRGGYLPKERREIERGLREGDILGVVSTNALELGVDI
HHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCEEECCCC
GQLQVCVMTGYPGSVASAWQQAGRAGRRHGESLIIMVANSTPIDQYIVRHPEYFFNRSPE
CCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCHHHHCCCCC
SARINPENLIILVDHLKCAAYELPFRADEEFGAMEVSDILEYLQEEAVLHRNGERYHWAS
CCEECCCCEEEEEECCCCHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECC
ESFPASNISLRSASQENVVIVDQSDIANVRIIGEMDRFSAMTLLHDEAIYLHEGVQYQVE
CCCCCCCCEEECCCCCCEEEEECCCCCCEEEEECHHHHHHHHHHCCCEEEEECCCCHHHH
KLDWDHKKAYVRKVDVEYYTDANLAVQLKVLEIDKTKEKSRTSLHYGDVTVNALPTIFKK
HCCCCHHHHHHEEECEEEEECCCEEEEEEEEEECCCHHHHCCEEEECCEEHHHHHHHHHH
IKMTTFENIGSGPIHLPEEELHTSAAWLEIKTADEDIGEKTLEQLLLGISNVLQHIVPVY
HHHHHHHCCCCCCCCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEE
IMCDRNDVHVVSQIKAAHTGLPTIFLYDHYPGGIGLAEEVFKRFSDINEAAKQLITHCPC
EEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
HDGCPSCIGTEIEGIKAKERILQLLDQMS
CCCCCHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKKSLTELISDLKGNENVVNWHEIEPREAKTRPMPESIDERIKAALSKRGIDELYTHQY
CCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
SAFQYVQKGESIVTVTPTASGKTLCYNLPVLQSIAQDETNRALYLFPTKALAQDQKSELN
HHHHHHHCCCEEEEEECCCCCCEEEEECHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHH
EIIDEMGIDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDMLHSAILPHHTKWVSLFENLK
HHHHHHCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCHHHHHHHCCCHHHHHHHHHCCC
YIVIDELHTYRGVFGSHVANVIRRLKRICRFYGSDPVFICTSATIANPKELGEQLTGKPM
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCE
RLVDDNGAPSGRKHFVFYNPPIVNKPLNIRRSATAEVNELAKEFLKNKVQTIVFARSRVR
EEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEIILSHIQELVKKEIGTKSIRGYRGGYLPKERREIERGLREGDILGVVSTNALELGVDI
HHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCEEECCCC
GQLQVCVMTGYPGSVASAWQQAGRAGRRHGESLIIMVANSTPIDQYIVRHPEYFFNRSPE
CCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCHHHHCCCCC
SARINPENLIILVDHLKCAAYELPFRADEEFGAMEVSDILEYLQEEAVLHRNGERYHWAS
CCEECCCCEEEEEECCCCHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECC
ESFPASNISLRSASQENVVIVDQSDIANVRIIGEMDRFSAMTLLHDEAIYLHEGVQYQVE
CCCCCCCCEEECCCCCCEEEEECCCCCCEEEEECHHHHHHHHHHCCCEEEEECCCCHHHH
KLDWDHKKAYVRKVDVEYYTDANLAVQLKVLEIDKTKEKSRTSLHYGDVTVNALPTIFKK
HCCCCHHHHHHEEECEEEEECCCEEEEEEEEEECCCHHHHCCEEEECCEEHHHHHHHHHH
IKMTTFENIGSGPIHLPEEELHTSAAWLEIKTADEDIGEKTLEQLLLGISNVLQHIVPVY
HHHHHHHCCCCCCCCCCHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCEE
IMCDRNDVHVVSQIKAAHTGLPTIFLYDHYPGGIGLAEEVFKRFSDINEAAKQLITHCPC
EEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
HDGCPSCIGTEIEGIKAKERILQLLDQMS
CCCCCHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377