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The map label for this gene is ctpA

Identifier: 16079017

GI number: 16079017

Start: 2131902

End: 2133302

Strand: Reverse

Name: ctpA

Synonym: BSU19590

Alternate gene names: 16079017

Gene position: 2133302-2131902 (Counterclockwise)

Preceding gene: 16079020

Following gene: 16079015

Centisome position: 50.6

GC content: 41.68

Gene sequence:

>1401_bases
TTGAAACGGCAATTAAAACTGTTTTTTATTGTGCTGATCACTGCAGTTGTCGCTTCGGCGCTTACTTTATTTATTACGGG
CAATTCCAGTATCCTGGGCCAAAAATCAGCAAGCACAGGAGACAGCAAGTTCGACAAATTAAATAAAGCGTATGAGCAAA
TCAAAAGTGATTATTACCAAAAAACAGATGATGACAAATTAGTAGACGGAGCAATTAAAGGAATGATTCAATCACTGGAT
GATCCGTATTCTACATATATGGATCAAGAGCAAGCGAAATCATTCGACGAGACGATTTCAGCATCTTTTGAAGGAATCGG
AGCCCAAGTAGAGGAGAAAGACGGAGAAATCCTTATTGTATCCCCAATTAAAGGTTCACCTGCTGAAAAAGCCGGTATCA
AACCGAGGGACCAAATCATTAAGGTAAATGGAAAAAGCGTAAAAGGCATGAATGTAAATGAAGCCGTCGCTTTAATCCGA
GGCAAAAAGGGCACAAAGGTGAAGCTTGAACTGAACAGAGCGGGAGTGGGGAATATCGATCTTTCCATTAAGCGCGATAC
CATTCCTGTAGAGACTGTCTATTCAGAGATGAAAGACAACAACATCGGAGAAATTCAAATCACTTCTTTCTCTGAAACAA
CAGCTAAAGAGCTGACAGATGCGATTGACAGTTTAGAGAAAAAAGGCGCCAAAGGCTATATTTTAGACTTGAGAGGCAAC
CCGGGCGGCTTAATGGAACAGGCGATTACGATGAGCAACCTGTTCATTGATAAAGGGAAAAACATCATGCAGGTTGAATA
CAAAAACGGTTCAAAAGAAGTCATGAAGGCCGAAAAAGAACGGAAAGTGACCAAGCCGACCGTCGTTTTAGTAAATGACG
GTACAGCAAGCGCAGCCGAAATTATGGCCGCTGCCCTTCATGAATCGTCAAACGTACCGTTAATCGGCGAGACGACATTC
GGCAAAGGTACAGTACAAACGGCAAAAGAATATGATGATGGCTCTACCGTCAAACTGACAGTTGCCAAATGGCTGACTGC
TGATGGCGAATGGATTCACAAAAAAGGCATCAAGCCTCAAGTGAAAGCAGAGCTGCCTGATTACGCGAAGCTGCCGTATT
TGGACGCAGATAAAACGTACAAATCAGGTGATACAGGCACAAACGTCAAAGTGGCTCAGAAAATGCTCAAAGCACTTGGT
TACAAGGTAAAGGTTAACAGTATGTATGACCAGGATTTTGTATCTGTCGTCAAACAGTTCCAGAAAAAAGAGAAGCTGAA
TGAAACAGGCATACTGACTGGCGATACAACAACGAAATTAATGATAGAACTTCAAAAGAAGCTGTCTGATAATGATACGC
AAATGGAAAAGGCAATTGAAACACTGAAAAAAGAAATGTAA

Upstream 100 bases:

>100_bases
GAAAAGCAAAAGAAGGGCGTTTCTCTTTCATTTCTGCTCCGAGTTGACGAATAAGAATTCGTCCATGATAATAATGTAAG
AAGAAAAAGGTGGTGTTTAA

Downstream 100 bases:

>100_bases
AAAAAACCATACGCGGCTGCCGCGTATGGTTTTTTTATGCGCCCTTTTGATTTGGATTAGCGTCTTGTTTTTTGCCAAAT
AAACCTTCAATGACAGGATT

Product: carboxy-terminal processing protease

Products: NA

Alternate protein names: C-terminal processing protease

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKRQLKLFFIVLITAVVASALTLFITGNSSILGQKSASTGDSKFDKLNKAYEQIKSDYYQKTDDDKLVDGAIKGMIQSLD
DPYSTYMDQEQAKSFDETISASFEGIGAQVEEKDGEILIVSPIKGSPAEKAGIKPRDQIIKVNGKSVKGMNVNEAVALIR
GKKGTKVKLELNRAGVGNIDLSIKRDTIPVETVYSEMKDNNIGEIQITSFSETTAKELTDAIDSLEKKGAKGYILDLRGN
PGGLMEQAITMSNLFIDKGKNIMQVEYKNGSKEVMKAEKERKVTKPTVVLVNDGTASAAEIMAAALHESSNVPLIGETTF
GKGTVQTAKEYDDGSTVKLTVAKWLTADGEWIHKKGIKPQVKAELPDYAKLPYLDADKTYKSGDTGTNVKVAQKMLKALG
YKVKVNSMYDQDFVSVVKQFQKKEKLNETGILTGDTTTKLMIELQKKLSDNDTQMEKAIETLKKEM

Sequences:

>Translated_466_residues
MKRQLKLFFIVLITAVVASALTLFITGNSSILGQKSASTGDSKFDKLNKAYEQIKSDYYQKTDDDKLVDGAIKGMIQSLD
DPYSTYMDQEQAKSFDETISASFEGIGAQVEEKDGEILIVSPIKGSPAEKAGIKPRDQIIKVNGKSVKGMNVNEAVALIR
GKKGTKVKLELNRAGVGNIDLSIKRDTIPVETVYSEMKDNNIGEIQITSFSETTAKELTDAIDSLEKKGAKGYILDLRGN
PGGLMEQAITMSNLFIDKGKNIMQVEYKNGSKEVMKAEKERKVTKPTVVLVNDGTASAAEIMAAALHESSNVPLIGETTF
GKGTVQTAKEYDDGSTVKLTVAKWLTADGEWIHKKGIKPQVKAELPDYAKLPYLDADKTYKSGDTGTNVKVAQKMLKALG
YKVKVNSMYDQDFVSVVKQFQKKEKLNETGILTGDTTTKLMIELQKKLSDNDTQMEKAIETLKKEM
>Mature_466_residues
MKRQLKLFFIVLITAVVASALTLFITGNSSILGQKSASTGDSKFDKLNKAYEQIKSDYYQKTDDDKLVDGAIKGMIQSLD
DPYSTYMDQEQAKSFDETISASFEGIGAQVEEKDGEILIVSPIKGSPAEKAGIKPRDQIIKVNGKSVKGMNVNEAVALIR
GKKGTKVKLELNRAGVGNIDLSIKRDTIPVETVYSEMKDNNIGEIQITSFSETTAKELTDAIDSLEKKGAKGYILDLRGN
PGGLMEQAITMSNLFIDKGKNIMQVEYKNGSKEVMKAEKERKVTKPTVVLVNDGTASAAEIMAAALHESSNVPLIGETTF
GKGTVQTAKEYDDGSTVKLTVAKWLTADGEWIHKKGIKPQVKAELPDYAKLPYLDADKTYKSGDTGTNVKVAQKMLKALG
YKVKVNSMYDQDFVSVVKQFQKKEKLNETGILTGDTTTKLMIELQKKLSDNDTQMEKAIETLKKEM

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Associated With The Periplasmic Protein Side Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1788134, Length=307, Percent_Identity=32.5732899022801, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTPA_BACSU (O34666)

Other databases:

- EMBL:   X98341
- EMBL:   AF015775
- EMBL:   AF006665
- EMBL:   AL009126
- PIR:   B69610
- RefSeq:   NP_389840.1
- HSSP:   P97879
- ProteinModelPortal:   O34666
- MEROPS:   S41.007
- EnsemblBacteria:   EBBACT00000002807
- GeneID:   940115
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU19590
- NMPDR:   fig|224308.1.peg.1963
- GenoList:   BSU19590
- GeneTree:   EBGT00050000001244
- HOGENOM:   HBG750030
- OMA:   RDINKHG
- ProtClustDB:   CLSK887429
- BioCyc:   BSUB:BSU19590-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477
- Gene3D:   G3DSA:1.10.101.10
- SMART:   SM00228
- SMART:   SM00245
- TIGRFAMs:   TIGR00225

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1; SSF50156 PDZ; SSF47090 PGBD_like

EC number: =3.4.21.102

Molecular weight: Translated: 51149; Mature: 51149

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50106 PDZ

Important sites: ACT_SITE 297-297 ACT_SITE 308-308 ACT_SITE 322-322

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQLKLFFIVLITAVVASALTLFITGNSSILGQKSASTGDSKFDKLNKAYEQIKSDYYQ
CCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
KTDDDKLVDGAIKGMIQSLDDPYSTYMDQEQAKSFDETISASFEGIGAQVEEKDGEILIV
CCCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEE
SPIKGSPAEKAGIKPRDQIIKVNGKSVKGMNVNEAVALIRGKKGTKVKLELNRAGVGNID
ECCCCCCCHHCCCCCCCCEEEECCCEECCCCHHHHHHEEECCCCCEEEEEECCCCCCCEE
LSIKRDTIPVETVYSEMKDNNIGEIQITSFSETTAKELTDAIDSLEKKGAKGYILDLRGN
EEEECCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
PGGLMEQAITMSNLFIDKGKNIMQVEYKNGSKEVMKAEKERKVTKPTVVLVNDGTASAAE
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHH
IMAAALHESSNVPLIGETTFGKGTVQTAKEYDDGSTVKLTVAKWLTADGEWIHKKGIKPQ
HHHHHHHCCCCCCEEECCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCHHHCCCCCC
VKAELPDYAKLPYLDADKTYKSGDTGTNVKVAQKMLKALGYKVKVNSMYDQDFVSVVKQF
HHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
QKKEKLNETGILTGDTTTKLMIELQKKLSDNDTQMEKAIETLKKEM
HHHHHCCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRQLKLFFIVLITAVVASALTLFITGNSSILGQKSASTGDSKFDKLNKAYEQIKSDYYQ
CCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
KTDDDKLVDGAIKGMIQSLDDPYSTYMDQEQAKSFDETISASFEGIGAQVEEKDGEILIV
CCCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEE
SPIKGSPAEKAGIKPRDQIIKVNGKSVKGMNVNEAVALIRGKKGTKVKLELNRAGVGNID
ECCCCCCCHHCCCCCCCCEEEECCCEECCCCHHHHHHEEECCCCCEEEEEECCCCCCCEE
LSIKRDTIPVETVYSEMKDNNIGEIQITSFSETTAKELTDAIDSLEKKGAKGYILDLRGN
EEEECCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
PGGLMEQAITMSNLFIDKGKNIMQVEYKNGSKEVMKAEKERKVTKPTVVLVNDGTASAAE
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHH
IMAAALHESSNVPLIGETTFGKGTVQTAKEYDDGSTVKLTVAKWLTADGEWIHKKGIKPQ
HHHHHHHCCCCCCEEECCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCHHHCCCCCC
VKAELPDYAKLPYLDADKTYKSGDTGTNVKVAQKMLKALGYKVKVNSMYDQDFVSVVKQF
HHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
QKKEKLNETGILTGDTTTKLMIELQKKLSDNDTQMEKAIETLKKEM
HHHHHCCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8996100; 9734814; 9384377