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The map label for this gene is yocS

Identifier: 16078995

GI number: 16078995

Start: 2106490

End: 2107455

Strand: Direct

Name: yocS

Synonym: BSU19350

Alternate gene names: 16078995

Gene position: 2106490-2107455 (Clockwise)

Preceding gene: 16078993

Following gene: 16079004

Centisome position: 49.97

GC content: 43.58

Gene sequence:

>966_bases
ATGGACATCATTAGAAAAATAAGCCATTTTGCAGGACAAACCTTTGGCATATGGGTCATTGTTTTTGCAGTGCTGGGATT
TTCTTTCCCATCTTTATTTACGTGGATCAGTTCTTATATTACGATTTTTCTCGGCATTATCATGTTTGGGATGGGCCTTA
CACTGCAAGCCGATGATTTCAAAGAGCTGGTCAGAAAGCCTTGGCAAGTTATTATTGGAGTAATAGCTCAGTATACGATC
ATGCCGCTCGTTGCTTTCGGCCTCGCATTTGGGCTTCATCTTCCAGCTGAAATCGCAGTTGGTGTTATTCTTGTCGGCTG
CTGTCCCGGGGGAACTGCATCTAATGTTATGACATTCTTAGCAAAAGGAAATACTGCCCTTTCTGTTGCGGTTACGACAA
TTTCTACCTTATTGGCACCTGTTGTAACACCGTTGTTGATTATGCTGTTTGCCAAAGAATGGCTTCCTGTCTCGCCGGGG
TCTTTGTTTATCTCAATCTTACAGGCGGTTTTATTTCCGATCATTGCAGGTCTGATTGTCAAAATGTTTTTCAGAAAACA
AGTGGCAAAAGCCGTACATGCCCTTCCGCTTGTTTCTGTCATTGGCATCGTTGCGATTGTCTCAGCTGTCGTCAGCGGCA
ATCGGGAAAATCTGCTTCAATCGGGGTTGCTCATTTTTTCAGTTGTTATCCTGCATAACGGTATCGGTTATTTACTGGGG
TTTCTTTGTGCAAAGCTTTTAAAAATGGATTACCCGTCTCAAAAAGCGATTGCAATCGAAGTCGGCATGCAAAACTCCGG
GCTTGGGGCTGCACTTGCCACGGCTCATTTCTCACCGCTATCTGCCGTACCAAGCGCAATATTCAGTGTGTGGCATAACC
TTTCAGGTTCTATGCTTGCAACATATTGGTCAAAAAAAGTGAAAAAGAAGCAAGCTGGATCCAAAAGCAGCAATCTATCA
CTTTAA

Upstream 100 bases:

>100_bases
AATATTGAATTATTCAGAAAATTATTTATAATAAGAGAATGTTATGAAATTTGTAAGAATTTCTGCTGAAGTTCTTGATA
AGTGTGTTAGGAGTGTTTTT

Downstream 100 bases:

>100_bases
ATATGCATCAAAAAGGGTACATCACTTTATCGTGATGTACCCTTTTTTATTATCCTTCTAATAAAAGCTGTTCAGGATCT
TCCAGTAAATTTTTGATTGT

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDIIRKISHFAGQTFGIWVIVFAVLGFSFPSLFTWISSYITIFLGIIMFGMGLTLQADDFKELVRKPWQVIIGVIAQYTI
MPLVAFGLAFGLHLPAEIAVGVILVGCCPGGTASNVMTFLAKGNTALSVAVTTISTLLAPVVTPLLIMLFAKEWLPVSPG
SLFISILQAVLFPIIAGLIVKMFFRKQVAKAVHALPLVSVIGIVAIVSAVVSGNRENLLQSGLLIFSVVILHNGIGYLLG
FLCAKLLKMDYPSQKAIAIEVGMQNSGLGAALATAHFSPLSAVPSAIFSVWHNLSGSMLATYWSKKVKKKQAGSKSSNLS
L

Sequences:

>Translated_321_residues
MDIIRKISHFAGQTFGIWVIVFAVLGFSFPSLFTWISSYITIFLGIIMFGMGLTLQADDFKELVRKPWQVIIGVIAQYTI
MPLVAFGLAFGLHLPAEIAVGVILVGCCPGGTASNVMTFLAKGNTALSVAVTTISTLLAPVVTPLLIMLFAKEWLPVSPG
SLFISILQAVLFPIIAGLIVKMFFRKQVAKAVHALPLVSVIGIVAIVSAVVSGNRENLLQSGLLIFSVVILHNGIGYLLG
FLCAKLLKMDYPSQKAIAIEVGMQNSGLGAALATAHFSPLSAVPSAIFSVWHNLSGSMLATYWSKKVKKKQAGSKSSNLS
L
>Mature_321_residues
MDIIRKISHFAGQTFGIWVIVFAVLGFSFPSLFTWISSYITIFLGIIMFGMGLTLQADDFKELVRKPWQVIIGVIAQYTI
MPLVAFGLAFGLHLPAEIAVGVILVGCCPGGTASNVMTFLAKGNTALSVAVTTISTLLAPVVTPLLIMLFAKEWLPVSPG
SLFISILQAVLFPIIAGLIVKMFFRKQVAKAVHALPLVSVIGIVAIVSAVVSGNRENLLQSGLLIFSVVILHNGIGYLLG
FLCAKLLKMDYPSQKAIAIEVGMQNSGLGAALATAHFSPLSAVPSAIFSVWHNLSGSMLATYWSKKVKKKQAGSKSSNLS
L

Specific function: Unknown

COG id: COG0385

COG function: function code R; Predicted Na+-dependent transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:bile acid symporter family

Homologues:

Organism=Homo sapiens, GI4506973, Length=254, Percent_Identity=34.251968503937, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI37537552, Length=292, Percent_Identity=26.027397260274, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4506971, Length=284, Percent_Identity=28.5211267605634, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI24308414, Length=244, Percent_Identity=29.9180327868852, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI58219066, Length=276, Percent_Identity=28.6231884057971, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI215422370, Length=233, Percent_Identity=27.4678111587983, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI9790143, Length=233, Percent_Identity=27.4678111587983, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI215422368, Length=233, Percent_Identity=28.3261802575107, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533076, Length=132, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859699, Length=248, Percent_Identity=30.241935483871, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YOCS_BACSU (O34524)

Other databases:

- EMBL:   AF027868
- EMBL:   AL009126
- PIR:   E69902
- RefSeq:   NP_389817.1
- ProteinModelPortal:   O34524
- EnsemblBacteria:   EBBACT00000003697
- GeneID:   939452
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU19350
- NMPDR:   fig|224308.1.peg.1940
- GenoList:   BSU19350
- GeneTree:   EBGT00070000032090
- HOGENOM:   HBG747007
- OMA:   SALFSVW
- ProtClustDB:   CLSK887424
- BioCyc:   BSUB:BSU19350-MONOMER
- InterPro:   IPR004710
- InterPro:   IPR002657
- PANTHER:   PTHR10361
- TIGRFAMs:   TIGR00841

Pfam domain/function: PF01758 SBF

EC number: NA

Molecular weight: Translated: 34252; Mature: 34252

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe75f58c)-; HASH(0xffca31c)-; HASH(0x102f7988)-; HASH(0xf3cf690)-; HASH(0xb7d801c)-; HASH(0xf1fff54)-; HASH(0xfff3204)-; HASH(0xf7a5e50)-; HASH(0x10091678)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIRKISHFAGQTFGIWVIVFAVLGFSFPSLFTWISSYITIFLGIIMFGMGLTLQADDF
CCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KELVRKPWQVIIGVIAQYTIMPLVAFGLAFGLHLPAEIAVGVILVGCCPGGTASNVMTFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCHHHHHHHH
AKGNTALSVAVTTISTLLAPVVTPLLIMLFAKEWLPVSPGSLFISILQAVLFPIIAGLIV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
KMFFRKQVAKAVHALPLVSVIGIVAIVSAVVSGNRENLLQSGLLIFSVVILHNGIGYLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
FLCAKLLKMDYPSQKAIAIEVGMQNSGLGAALATAHFSPLSAVPSAIFSVWHNLSGSMLA
HHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHH
TYWSKKVKKKQAGSKSSNLSL
HHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure
MDIIRKISHFAGQTFGIWVIVFAVLGFSFPSLFTWISSYITIFLGIIMFGMGLTLQADDF
CCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KELVRKPWQVIIGVIAQYTIMPLVAFGLAFGLHLPAEIAVGVILVGCCPGGTASNVMTFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCHHHHHHHH
AKGNTALSVAVTTISTLLAPVVTPLLIMLFAKEWLPVSPGSLFISILQAVLFPIIAGLIV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
KMFFRKQVAKAVHALPLVSVIGIVAIVSAVVSGNRENLLQSGLLIFSVVILHNGIGYLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
FLCAKLLKMDYPSQKAIAIEVGMQNSGLGAALATAHFSPLSAVPSAIFSVWHNLSGSMLA
HHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHH
TYWSKKVKKKQAGSKSSNLSL
HHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377