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The map label for this gene is yoaU

Identifier: 16078936

GI number: 16078936

Start: 2044956

End: 2045828

Strand: Reverse

Name: yoaU

Synonym: BSU18760

Alternate gene names: 16078936

Gene position: 2045828-2044956 (Counterclockwise)

Preceding gene: 16078938

Following gene: 16078932

Centisome position: 48.53

GC content: 41.24

Gene sequence:

>873_bases
ATGGTTATGAACATGAACCATCTTCACATATTTGTAAAAGTTGGGGAGAAATTAAATATTACAGAAGCGGCAAAAGAATT
GTTCATCTCTCAGCCGGCGGTAAGTAAAGCGATAAAAAACCTGGAGAGCTCACTGCAGCTCAAATTATTGATCAGGGATA
AACATCATGGTTTAATGCTGACTGACATCGGAAAAGAAATATTGCTGCTGGCGAGGCAAATGAAGGGAATTGAAAGCAAA
ATATATCAAGTAGCCAACCGGGAAAACAAGCTGTTAAACGGGAAGGTGAAAATTGGTTCATTTCCTGCAGTTTCAACAAA
TATCATGCCACAGGCGATTGCGGCATTCAGATCAAACTACCCGCTGATCCGCATAGAATTGATCGAAGGAACCTCTGACC
AAATAAAAGGATGGGTTGAAGATCGGACGGTTGATATCGGGATCGCAGCATCTCCATTTGAACCGTTTGAAAATCAGCTA
TTGTGTAACGACTATATGGTGGCCGTCATCCCGCCGCAGCGTGACGAATTAAAACTTGAAAAGCATGTCGACCTTGAAAC
ATATCAAGATGACCTCATTTTTTGTAAAGGCGGTCATGAAATCGCGATGTCAAACGCATTTTCGCAATACAACATCGAAT
TAAAGGAAAACTTAACTGTGCAAAATGCCGAAACCTTGATTAATATGGTCAAAAATAACTTGGGTATCGGCATCATTTCA
AACTTTACACTTTCATCCGTCCCGCATCAATTGATTAAAAAGGACATCTTTCCTAGGGTCACACGCGATATTGGCGTCAT
CGCACATTCATTTGAAGAGATAACGCCGGCGGCGCATGAGTTTGTCAAAGTGTTGAAAGCAGTTGTAATCTGA

Upstream 100 bases:

>100_bases
AATGAAGCCGCCTTTCTTGTTAAAATATCGTGCTGGTTTCTATCATATGTTACATTTATGTATAACTGAAATACATTTTT
ATTATTGGGGGTATAACCAA

Downstream 100 bases:

>100_bases
ATCAGTTATCGTGTTGCGATGAAATTTGAAGAAGATGAATACTCACCGGCAGAGTTACATAAAAGAAAAAAGCAACCATT
TGAACGTTGCTTTTCACTCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MVMNMNHLHIFVKVGEKLNITEAAKELFISQPAVSKAIKNLESSLQLKLLIRDKHHGLMLTDIGKEILLLARQMKGIESK
IYQVANRENKLLNGKVKIGSFPAVSTNIMPQAIAAFRSNYPLIRIELIEGTSDQIKGWVEDRTVDIGIAASPFEPFENQL
LCNDYMVAVIPPQRDELKLEKHVDLETYQDDLIFCKGGHEIAMSNAFSQYNIELKENLTVQNAETLINMVKNNLGIGIIS
NFTLSSVPHQLIKKDIFPRVTRDIGVIAHSFEEITPAAHEFVKVLKAVVI

Sequences:

>Translated_290_residues
MVMNMNHLHIFVKVGEKLNITEAAKELFISQPAVSKAIKNLESSLQLKLLIRDKHHGLMLTDIGKEILLLARQMKGIESK
IYQVANRENKLLNGKVKIGSFPAVSTNIMPQAIAAFRSNYPLIRIELIEGTSDQIKGWVEDRTVDIGIAASPFEPFENQL
LCNDYMVAVIPPQRDELKLEKHVDLETYQDDLIFCKGGHEIAMSNAFSQYNIELKENLTVQNAETLINMVKNNLGIGIIS
NFTLSSVPHQLIKKDIFPRVTRDIGVIAHSFEEITPAAHEFVKVLKAVVI
>Mature_290_residues
MVMNMNHLHIFVKVGEKLNITEAAKELFISQPAVSKAIKNLESSLQLKLLIRDKHHGLMLTDIGKEILLLARQMKGIESK
IYQVANRENKLLNGKVKIGSFPAVSTNIMPQAIAAFRSNYPLIRIELIEGTSDQIKGWVEDRTVDIGIAASPFEPFENQL
LCNDYMVAVIPPQRDELKLEKHVDLETYQDDLIFCKGGHEIAMSNAFSQYNIELKENLTVQNAETLINMVKNNLGIGIIS
NFTLSSVPHQLIKKDIFPRVTRDIGVIAHSFEEITPAAHEFVKVLKAVVI

Specific function: This Protein Is A Positive Regulator Of Gene Expression For The Cysteine Regulon, A System Of 10 Or More Loci Involved In The Biosynthesis Of L-Cysteine From Inorganic Sulfate. The Inducer For Cysb Is N-Acetylserine. Cysb Inhibits Its Own Transcription.

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787530, Length=279, Percent_Identity=24.3727598566308, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788296, Length=253, Percent_Identity=28.0632411067194, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788887, Length=295, Percent_Identity=24.406779661017, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788748, Length=304, Percent_Identity=24.3421052631579, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789204, Length=253, Percent_Identity=23.7154150197628, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=299, Percent_Identity=23.4113712374582, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787879, Length=260, Percent_Identity=27.6923076923077, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=273, Percent_Identity=21.978021978022, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI157672245, Length=196, Percent_Identity=28.0612244897959, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789173, Length=171, Percent_Identity=28.0701754385965, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788481, Length=300, Percent_Identity=26.3333333333333, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788297, Length=132, Percent_Identity=37.8787878787879, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081904, Length=147, Percent_Identity=27.2108843537415, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YOAU_BACSU (O34701)

Other databases:

- EMBL:   AF027868
- EMBL:   AL009126
- PIR:   F69897
- RefSeq:   NP_389757.1
- ProteinModelPortal:   O34701
- SMR:   O34701
- EnsemblBacteria:   EBBACT00000000455
- GeneID:   940127
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU18760
- NMPDR:   fig|224308.1.peg.1879
- GenoList:   BSU18760
- GeneTree:   EBGT00070000031793
- HOGENOM:   HBG685425
- OMA:   IRTENDM
- ProtClustDB:   CLSK2752417
- BioCyc:   BSUB:BSU18760-MONOMER
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 32581; Mature: 32581

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMNMNHLHIFVKVGEKLNITEAAKELFISQPAVSKAIKNLESSLQLKLLIRDKHHGLML
CEECCCEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCEEEEEEEEECCCCEEE
TDIGKEILLLARQMKGIESKIYQVANRENKLLNGKVKIGSFPAVSTNIMPQAIAAFRSNY
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECEEEECCCCCCCCCHHHHHHHHHHCCC
PLIRIELIEGTSDQIKGWVEDRTVDIGIAASPFEPFENQLLCNDYMVAVIPPQRDELKLE
CEEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCEEEEEECCCCCCCHHH
KHVDLETYQDDLIFCKGGHEIAMSNAFSQYNIELKENLTVQNAETLINMVKNNLGIGIIS
HCCCCEECCCCEEEECCCCEEEECCCCHHEEEEEECCCEECHHHHHHHHHHHCCCEEEEC
NFTLSSVPHQLIKKDIFPRVTRDIGVIAHSFEEITPAAHEFVKVLKAVVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVMNMNHLHIFVKVGEKLNITEAAKELFISQPAVSKAIKNLESSLQLKLLIRDKHHGLML
CEECCCEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCEEEEEEEEECCCCEEE
TDIGKEILLLARQMKGIESKIYQVANRENKLLNGKVKIGSFPAVSTNIMPQAIAAFRSNY
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECEEEECCCCCCCCCHHHHHHHHHHCCC
PLIRIELIEGTSDQIKGWVEDRTVDIGIAASPFEPFENQLLCNDYMVAVIPPQRDELKLE
CEEEEEEECCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCEEEEEECCCCCCCHHH
KHVDLETYQDDLIFCKGGHEIAMSNAFSQYNIELKENLTVQNAETLINMVKNNLGIGIIS
HCCCCEECCCCEEEECCCCEEEECCCCHHEEEEEECCCEECHHHHHHHHHHHCCCEEEEC
NFTLSSVPHQLIKKDIFPRVTRDIGVIAHSFEEITPAAHEFVKVLKAVVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377