Click here to switch to the map view.

The map label for this gene is yngB

Identifier: 16078879

GI number: 16078879

Start: 1946702

End: 1947595

Strand: Direct

Name: yngB

Synonym: BSU18180

Alternate gene names: 16078879

Gene position: 1946702-1947595 (Clockwise)

Preceding gene: 16078878

Following gene: 16078880

Centisome position: 46.18

GC content: 46.09

Gene sequence:

>894_bases
ATGAGAAAAAAAGTGAGAAAAGCGGTTATACCCGCAGCGGGTTTAGGAACGAGATTTCTGCCGGCGACAAAGGCGCAGCC
TAAAGAAATGCTTCCAATCGTCGACAAACCAGCAATCCAATATATTGTAGAAGAGGCCGCAGAGTCAGGAATTGAAGATA
TACTGATTATTACAGGGAGAAACAAACGCTCGATTGAAGATCATTTTGATCGGTCGGCGGAATTGGAATTCAATCTCCGG
GAAAAAGGCAAGACGGAGACACTTAAGGAAATGCAGCAGATTGCCGATTTGGCCAACATTCATTACATCCGCCAGAAAGA
ACCGCTCGGATTAGGCCATGCGGTGCTGTGTGCGGAGCATTTTATCGGAGATGAGCCTTTTGCTGTTCTCTTAGGTGATG
ATATTATGGTGTCTGAAACACCGGCTCTTCGGCAATTAATGGATGTATATGACGTTTATGGCACAGAGGTTGTCGGTGTA
CAGTCAGTTCTCCCTGAGGATGTCAGCAAATATGGTATTATAAATACATCAGGGTCTCAAGGGCATGTATATGAAGTGAA
CGATTTAGTGGAAAAGCCTTCTCCTGAAGAAGCACCTTCGGAAATCGCAGTAATGGGACGTTATGTGCTGAATTCTTCGA
TCTTCTCCGTTTTGAAGACAATTGGCAGAGGCGCGGGCAACGAAATTCAGCTGACAGATGCGCTTCGTGAGGTTTGCCGT
AAGGAGCCGATCCATGCCCGGCTGCTGGAAGGAAATCGATATGACATTGGCGATAAGCTGGGCTGTTTTAAAGCGAGCAC
CGAAATCGGCTTAATGCGTCCCGAAATGAGATCTCAGCTTTTGGCCTATTTAGAAGATGTGATCAAACGGGAAACGAAAG
AAATGCTGCGGTAA

Upstream 100 bases:

>100_bases
CGCCGCCACTATCGGCGGAATGATGATGAATTTTATCGGAAACCGAATCTGGGTATTTGGAGATTCGCTGAAAAACATAC
AGGATCAGGAGTGAAGATGA

Downstream 100 bases:

>100_bases
AAAAATTGTAACCATCTTGCTCGTCAATCAGTCATATAATAGTGAAAAAGATTAGGACAGGTTGTGAAGAATGTGGGCAG
TTTGATAAGCGAAATTTTAA

Product: UTP-sugar-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEEAAESGIEDILIITGRNKRSIEDHFDRSAELEFNLR
EKGKTETLKEMQQIADLANIHYIRQKEPLGLGHAVLCAEHFIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGV
QSVLPEDVSKYGIINTSGSQGHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIGRGAGNEIQLTDALREVCR
KEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRPEMRSQLLAYLEDVIKRETKEMLR

Sequences:

>Translated_297_residues
MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEEAAESGIEDILIITGRNKRSIEDHFDRSAELEFNLR
EKGKTETLKEMQQIADLANIHYIRQKEPLGLGHAVLCAEHFIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGV
QSVLPEDVSKYGIINTSGSQGHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIGRGAGNEIQLTDALREVCR
KEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRPEMRSQLLAYLEDVIKRETKEMLR
>Mature_297_residues
MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEEAAESGIEDILIITGRNKRSIEDHFDRSAELEFNLR
EKGKTETLKEMQQIADLANIHYIRQKEPLGLGHAVLCAEHFIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGV
QSVLPEDVSKYGIINTSGSQGHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIGRGAGNEIQLTDALREVCR
KEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRPEMRSQLLAYLEDVIKRETKEMLR

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family

Homologues:

Organism=Escherichia coli, GI1787488, Length=295, Percent_Identity=43.3898305084746, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1788355, Length=276, Percent_Identity=43.1159420289855, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1788351, Length=235, Percent_Identity=31.4893617021277, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790224, Length=234, Percent_Identity=28.6324786324786, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI133931050, Length=258, Percent_Identity=27.1317829457364, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): YNGB_BACSU (O31822)

Other databases:

- EMBL:   AL009126
- PIR:   G69892
- RefSeq:   NP_389700.1
- ProteinModelPortal:   O31822
- SMR:   O31822
- EnsemblBacteria:   EBBACT00000003654
- GeneID:   936791
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU18180
- NMPDR:   fig|224308.1.peg.1821
- GenoList:   BSU18180
- GeneTree:   EBGT00050000000561
- HOGENOM:   HBG688195
- OMA:   MAEDEFL
- PhylomeDB:   O31822
- ProtClustDB:   CLSK887363
- BioCyc:   BSUB:BSU18180-MONOMER
- InterPro:   IPR005771
- InterPro:   IPR005835
- TIGRFAMs:   TIGR01099

Pfam domain/function: PF00483 NTP_transferase

EC number: =2.7.7.9

Molecular weight: Translated: 33148; Mature: 33148

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEEAAESGIEDILIITGR
CCHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECC
NKRSIEDHFDRSAELEFNLREKGKTETLKEMQQIADLANIHYIRQKEPLGLGHAVLCAEH
CCCCHHHHCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
FIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGVQSVLPEDVSKYGIINTSGSQ
HCCCCCEEEEECCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEECCCCC
GHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIGRGAGNEIQLTDALREVCR
CCEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
KEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRPEMRSQLLAYLEDVIKRETKEMLR
CCCCEEEEECCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEEAAESGIEDILIITGR
CCHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECC
NKRSIEDHFDRSAELEFNLREKGKTETLKEMQQIADLANIHYIRQKEPLGLGHAVLCAEH
CCCCHHHHCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
FIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGVQSVLPEDVSKYGIINTSGSQ
HCCCCCEEEEECCCEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEECCCCC
GHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIGRGAGNEIQLTDALREVCR
CCEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
KEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRPEMRSQLLAYLEDVIKRETKEMLR
CCCCEEEEECCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377