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The map label for this gene is ccdA

Identifier: 16078856

GI number: 16078856

Start: 1923234

End: 1923941

Strand: Direct

Name: ccdA

Synonym: BSU17930

Alternate gene names: 16078856

Gene position: 1923234-1923941 (Clockwise)

Preceding gene: 16078854

Following gene: 16078857

Centisome position: 45.62

GC content: 41.95

Gene sequence:

>708_bases
ATGGGAGACGTGAATTATTTTTTGACATTCGGAGCGGGGTTTTTATCCTTTATTTCGCCTTGCTGCCTGCCGCTTTACCC
AGCTTTTTTGTCATATATTACAGGGGTCAGCATGGACGATGTAAAAACTGAAAAGCTGCTGCTGCAGAAAAGAAGCTTGT
TTCATACTTTGTGTTTTTTGCTTGGCTTTTCAGTCATTTTTATTGCTTTAGGCTATGGAACATCTTTTATTGGCAGCCTG
TTTAGGGATTATCACGATGCGATTCGGCAAATTGGCGCGTTGCTTATTATTTTGTTCGGTTTCATTACACTCGGTGTGTT
CCGGCCTGAGGCTATGATGAAAGAGCGGAGAATCCATTTTAAGCATAAACCAAGCGGGTTTTTAGGGTCGGTCTTAATCG
GAATGGCATTTGCAGCTGGATGGACACCATGTACCGGTCCGATATTAGCTGCTGTTATCACACTTGCAGGCACCAATCCG
GGCTCAGCGGTGCCATACATGATGTTATATGTACTCGGTTTTGCGGTACCGTTTCTTTTATTGTCTTTTTTTATCACAAA
GCTGAAGTGGATAAGGAAGAACCAGCTTTTCATTATGAAAGCTGGTGGCGTTTTGATGATTGTGATTGGTGTGCTGTTAT
TCTTTAATTGGATGAGCCTGATCATTATTTTGCTGTCAGATCTTTTTGGAGGCTTTACTGGTTTTTGA

Upstream 100 bases:

>100_bases
GTTTTTTCTGAAAATAGAAATCCTTCAAGTGAAAGTGTTAAAAAAATGAAATGATTTTGTCATAACTTGAAGGAATGTCA
AATCATGAAGGGATGATGAC

Downstream 100 bases:

>100_bases
CGGTAAATTACTTTCGTACTACTACTAATCCTTTTGTTTTTGGTACAATAAGACTATTATCTGTGGAAATCGATTGTTGG
AGGGGAATATGACAAGAGTT

Product: cytochrome c-type biogenesis protein CcdA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MGDVNYFLTFGAGFLSFISPCCLPLYPAFLSYITGVSMDDVKTEKLLLQKRSLFHTLCFLLGFSVIFIALGYGTSFIGSL
FRDYHDAIRQIGALLIILFGFITLGVFRPEAMMKERRIHFKHKPSGFLGSVLIGMAFAAGWTPCTGPILAAVITLAGTNP
GSAVPYMMLYVLGFAVPFLLLSFFITKLKWIRKNQLFIMKAGGVLMIVIGVLLFFNWMSLIIILLSDLFGGFTGF

Sequences:

>Translated_235_residues
MGDVNYFLTFGAGFLSFISPCCLPLYPAFLSYITGVSMDDVKTEKLLLQKRSLFHTLCFLLGFSVIFIALGYGTSFIGSL
FRDYHDAIRQIGALLIILFGFITLGVFRPEAMMKERRIHFKHKPSGFLGSVLIGMAFAAGWTPCTGPILAAVITLAGTNP
GSAVPYMMLYVLGFAVPFLLLSFFITKLKWIRKNQLFIMKAGGVLMIVIGVLLFFNWMSLIIILLSDLFGGFTGF
>Mature_234_residues
GDVNYFLTFGAGFLSFISPCCLPLYPAFLSYITGVSMDDVKTEKLLLQKRSLFHTLCFLLGFSVIFIALGYGTSFIGSLF
RDYHDAIRQIGALLIILFGFITLGVFRPEAMMKERRIHFKHKPSGFLGSVLIGMAFAAGWTPCTGPILAAVITLAGTNPG
SAVPYMMLYVLGFAVPFLLLSFFITKLKWIRKNQLFIMKAGGVLMIVIGVLLFFNWMSLIIILLSDLFGGFTGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCDA_BACSU (P45706)

Other databases:

- EMBL:   Z73234
- EMBL:   X87845
- EMBL:   AL009126
- PIR:   D69597
- RefSeq:   NP_389676.1
- ProteinModelPortal:   P45706
- EnsemblBacteria:   EBBACT00000001694
- GeneID:   937140
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU17930
- NMPDR:   fig|224308.1.peg.1797
- GenoList:   BSU17930
- GeneTree:   EBGT00050000001122
- HOGENOM:   HBG733703
- OMA:   ITGVSMD
- ProtClustDB:   CLSK2752411
- BioCyc:   BSUB:BSU17930-MONOMER
- InterPro:   IPR003834

Pfam domain/function: PF02683 DsbD

EC number: NA

Molecular weight: Translated: 26008; Mature: 25877

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf3eebb8)-; HASH(0xe4aa17c)-; HASH(0xf3db598)-; HASH(0xce71b04)-; HASH(0xf77e6a0)-; HASH(0xf3b0210)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDVNYFLTFGAGFLSFISPCCLPLYPAFLSYITGVSMDDVKTEKLLLQKRSLFHTLCFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSVIFIALGYGTSFIGSLFRDYHDAIRQIGALLIILFGFITLGVFRPEAMMKERRIHF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
KHKPSGFLGSVLIGMAFAAGWTPCTGPILAAVITLAGTNPGSAVPYMMLYVLGFAVPFLL
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LSFFITKLKWIRKNQLFIMKAGGVLMIVIGVLLFFNWMSLIIILLSDLFGGFTGF
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
GDVNYFLTFGAGFLSFISPCCLPLYPAFLSYITGVSMDDVKTEKLLLQKRSLFHTLCFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSVIFIALGYGTSFIGSLFRDYHDAIRQIGALLIILFGFITLGVFRPEAMMKERRIHF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
KHKPSGFLGSVLIGMAFAAGWTPCTGPILAAVITLAGTNPGSAVPYMMLYVLGFAVPFLL
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LSFFITKLKWIRKNQLFIMKAGGVLMIVIGVLLFFNWMSLIIILLSDLFGGFTGF
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773