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The map label for this gene is yndN

Identifier: 16078847

GI number: 16078847

Start: 1916663

End: 1917097

Strand: Direct

Name: yndN

Synonym: BSU17840

Alternate gene names: 16078847

Gene position: 1916663-1917097 (Clockwise)

Preceding gene: 16078845

Following gene: 16078849

Centisome position: 45.47

GC content: 37.01

Gene sequence:

>435_bases
GTGGAGATAAAAGGAATCAATCACTTGCTATTTTCAGTTTCGCATTTGGATACATCGATTGATTTTTATCAAAAAGTGTT
TGGTGCAAAGCTTTTGGTAAAGGGAAGAACAACTGCATATTTTGATATGAACGGCATCTGGCTAGCGCTTAATGAAGAAC
CAGACATCCCGAGAAATGACATTAAGCTTTCTTATACCCATATTGCTTTTACAATTGAAGATCATGAATTTGAGGAGATG
TCAGCTAAATTAAAAAGACTTCATGTCAATATTCTGCCTGGCAGAGAACGAGATGAACGCGATCGAAAATCAATTTATTT
TACCGACCCTGACGGCCACAAATTTGAATTTCATACCGGAACCCTTCAAGACAGGCTTCGATATTACAAACAAGAAAAAA
CGCATATGCACTTTTATGATGAAACGGCCTTTTGA

Upstream 100 bases:

>100_bases
TCCGTTTTTGTTTACACTGGTATTTTTTTCAGCTGTATGAAACTTTCTTATGAAAAAAGTCGTATATGTGGATGATCAGC
TTTCAAGGGGGGAATGATTT

Downstream 100 bases:

>100_bases
TAGCACAACCATATTTCATATAAGGTTAAATTTAAAGAAGGGTGTTGGTGGAGACTTTATGTTTGGGGAAGGTTTCTACC
CGACTTGTTCAACGATGCCA

Product: fosfomycin resistance protein FosB

Products: NA

Alternate protein names: Fosfomycin resistance protein

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MEIKGINHLLFSVSHLDTSIDFYQKVFGAKLLVKGRTTAYFDMNGIWLALNEEPDIPRNDIKLSYTHIAFTIEDHEFEEM
SAKLKRLHVNILPGRERDERDRKSIYFTDPDGHKFEFHTGTLQDRLRYYKQEKTHMHFYDETAF

Sequences:

>Translated_144_residues
MEIKGINHLLFSVSHLDTSIDFYQKVFGAKLLVKGRTTAYFDMNGIWLALNEEPDIPRNDIKLSYTHIAFTIEDHEFEEM
SAKLKRLHVNILPGRERDERDRKSIYFTDPDGHKFEFHTGTLQDRLRYYKQEKTHMHFYDETAF
>Mature_144_residues
MEIKGINHLLFSVSHLDTSIDFYQKVFGAKLLVKGRTTAYFDMNGIWLALNEEPDIPRNDIKLSYTHIAFTIEDHEFEEM
SAKLKRLHVNILPGRERDERDRKSIYFTDPDGHKFEFHTGTLQDRLRYYKQEKTHMHFYDETAF

Specific function: Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fosfomycin resistance protein family. FosB subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FOSB_BACSU (O31817)

Other databases:

- EMBL:   AL009126
- PIR:   E69890
- RefSeq:   NP_389667.1
- ProteinModelPortal:   O31817
- SMR:   O31817
- EnsemblBacteria:   EBBACT00000003446
- GeneID:   938817
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU17840
- NMPDR:   fig|224308.1.peg.1788
- GenoList:   BSU17840
- GeneTree:   EBGT00050000001020
- HOGENOM:   HBG704761
- OMA:   QDRLNYY
- ProtClustDB:   PRK04101
- BioCyc:   BSUB:BSU17840-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01512
- InterPro:   IPR004360
- InterPro:   IPR022858

Pfam domain/function: PF00903 Glyoxalase

EC number: NA

Molecular weight: Translated: 17173; Mature: 17173

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKGINHLLFSVSHLDTSIDFYQKVFGAKLLVKGRTTAYFDMNGIWLALNEEPDIPRND
CCCCCHHHHEEEHHHCCCHHHHHHHHHCCEEEEECCCEEEEECCCEEEEECCCCCCCCCC
IKLSYTHIAFTIEDHEFEEMSAKLKRLHVNILPGRERDERDRKSIYFTDPDGHKFEFHTG
EEEEEEEEEEEECCCCHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEECCCCCEEEEECC
TLQDRLRYYKQEKTHMHFYDETAF
CHHHHHHHHHCCCCEEEEEECCCC
>Mature Secondary Structure
MEIKGINHLLFSVSHLDTSIDFYQKVFGAKLLVKGRTTAYFDMNGIWLALNEEPDIPRND
CCCCCHHHHEEEHHHCCCHHHHHHHHHCCEEEEECCCEEEEECCCEEEEECCCCCCCCCC
IKLSYTHIAFTIEDHEFEEMSAKLKRLHVNILPGRERDERDRKSIYFTDPDGHKFEFHTG
EEEEEEEEEEEECCCCHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEECCCCCEEEEECC
TLQDRLRYYKQEKTHMHFYDETAF
CHHHHHHHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11244082