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The map label for this gene is polC

Identifier: 16078721

GI number: 16078721

Start: 1727133

End: 1731446

Strand: Direct

Name: polC

Synonym: BSU16580

Alternate gene names: 16078721

Gene position: 1727133-1731446 (Clockwise)

Preceding gene: 16078720

Following gene: 16078722

Centisome position: 40.97

GC content: 42.72

Gene sequence:

>4314_bases
ATGGAACAGTTATCAGTAAACAGAAGGCAGTTTCAAATTCTTCTGCAGCAGATTAATATGACAGATGATACCTTCATGAC
ATACTTTGAACATGGCGAGATTAAAAAGCTGACAATTCACAAAGCTTCTAAGTCTTGGCATTTTCATTTTCAATTTAAAT
CTTTGCTGCCTTTTCAAATATATGACACATTAACAACGAGGCTGACGCAATCGTTTGCCCACATAGCAAAAGTGACATCT
TCAATTGAAGTTCAGGATGCCGAGGTCAGTGAAAGTATCGTTCAAGACTACTGGTCACGCTGCATTGAAGAACTGCAGGG
CATTTCGCCGCCGATTATCAGTCTTTTAAACCAGCAAAAACCGAAGCTGAAGGGCAATAAACTGATTGTCAAAACCAAAA
CAGATACAGAAGCGGCTGCGCTAAAGAACAAATACAGTTCCATGATTCAAGCAGAATACCGTCAATTTGGCTTTCCGGAT
CTTCAGCTTGATGCTGAAATATTTGTATCCGAGCAAGAAGTTCAAAAGTTTCGGGAGCAAAAGCTTGCGGAAGACCAAGA
GCGGGCTATGCAGGCCTTGATTGAAATGGAGAAGAAAGATAAAGAAAGTGATGAAGACCAAGCACCATCTGGTCCTCTTG
TTATCGGTTATCAAATTAAAGATAACGAGGAAATCCGAACACTTGACAGCATCATGGACGAAGAACGGAGAATTACGGTC
CAAGGTTATGTGTTTGATGTGGAGACGCGCGAGCTGAAGAGCGGGCGCACGCTGTGTATCTTCAAAATTACAGACTATAC
AAATAGTATTTTGATCAAAATGTTTGCACGTGAAAAAGAAGATGCGGCGCTGATGAAGTCTCTGAAAAAAGGAATGTGGG
TAAAAGCACGCGGAAGCATTCAAAATGATACATTTGTCAGAGACCTTGTCATGATCGCAAATGACGTAAACGAAATAAAA
GCAAAAACCCGTGAAGATTCAGCACCTGAAGGAGAAAAAAGAGTGGAATTGCATCTTCATTCCCCAATGAGCCAAATGGA
TGCTGTTACGGGTATCGGAAAGCTTGTCGAACAGGCGAAAAAATGGGGGCATGAGGCCATCGCTTTGACCGACCATGCTG
TCGTTCAATCCTTCCCTGATGCGTATTCTGCGGCCAAAAAGCATGGAATTAAAATGATTTACGGGATGGAAGCGAATCTC
GTGGATGATGGCGTGCCAATTGCTTATAATGCCGCACATCGTCTGCTCGAAGAAGAAACATATGTTGTTTTTGACGTTGA
GACGACAGGATTGTCTGCTGTATACGATACCATTATTGAGCTGGCTGCAGTAAAAGTAAAAGGCGGAGAAATTATTGATA
AATTTGAGGCGTTTGCGAACCCGCATCGTCCGCTTTCCGCCACAATCATAGAGCTGACAGGGATCACAGATGATATGCTA
CAAGACGCTCCGGATGTCGTAGATGTAATAAGAGATTTCAGAGAATGGATTGGCGATGATATTCTTGTCGCTCATAATGC
AAGCTTTGATATGGGATTCTTAAATGTAGCCTATAAAAAACTTCTTGAAGTCGAAAAAGCTAAAAACCCAGTCATTGATA
CGCTTGAACTTGGACGTTTTCTCTATCCGGAATTTAAGAACCACCGGTTGAACACACTTTGTAAAAAGTTTGATATCGAG
CTCACACAGCATCACCGTGCGATCTATGATACTGAGGCAACCGCTTATTTGCTTCTGAAAATGCTGAAAGACGCAGCTGA
AAAAGGTATTCAGTACCATGATGAGTTGAATGAAAATATGGGTCAGTCCAATGCTTATCAAAGATCAAGACCGTATCATG
CAACATTACTTGCCGTGAACAGCACGGGACTTAAAAATTTATTTAAGCTTGTGTCACTTTCTCATATTCATTATTTTTAC
AGAGTGCCGCGTATTCCGAGATCTCAGCTTGAGAAATACAGGGAAGGGCTTCTGATCGGTTCTGCTTGTGACAGGGGAGA
GGTTTTTGAGGGAATGATGCAAAAATCGCCTGAAGAGGTGGAAGATATCGCGTCATTCTATGATTACCTTGAGGTTCAGC
CGCCTGAAGTGTATCGTCACTTGCTGGAGCTTGAACTGGTCCGTGATGAAAAAGCGCTGAAAGAAATTATTGCGAATATC
ACGAAGCTGGGGGAAAAGCTTAATAAACCGGTTGTTGCTACGGGAAATGTTCATTACTTGAATGATGAGGATAAAATCTA
CAGAAAGATTTTAATATCCTCACAAGGCGGGGCAAATCCGCTGAATAGGCATGAACTGCCGAAAGTGCATTTCAGAACGA
CAGACGAAATGCTTGAAGCTTTTTCTTTCTTAGGTGAAGAAAAAGCGAAGGAGATCGTAGTCACCAATACCCAAAAGGTT
GCTTCTTTAGTTGATGACATCAAGCCGATTAAAGATGATTTATATACGCCGAAAATCGAAGGCGCTGATGAAGAGATCAG
AGAAATGAGCTATCAGCGTGCAAGAAGCATTTACGGGGAAGAGCTGCCTGAAATTGTCGAAGCGCGGATTGAAAAAGAGT
TAAAGAGTATTATTGGCCACGGATTTGCTGTTATTTACTTGATCTCTCACAAACTTGTAAAACGTTCACTAGATGACGGG
TATCTCGTTGGTTCCCGTGGTTCCGTAGGATCTTCATTAGTTGCGACACTTACTGAGATTACTGAGGTAAACCCGCTGCC
GCCGCACTATGTTTGTCCTGAGTGCCAGCATTCTGAGTTCTTTAATGACGGTTCTGTCGGTTCTGGTTTTGACCTGCCTG
ACAAGACATGCCCTCATTGCGGAACGCCTTTGAAAAAAGACGGCCATGATATTCCATTTGAAACGTTCTTAGGATTTAAA
GGGGACAAAGTACCTGATATCGATTTGAACTTCTCAGGGGAATATCAGCCGCAAGCACACAATTACACAAAAGTATTGTT
CGGAGAAGACAATGTATATCGTGCGGGAACAATAGGCACGGTGGCAGAAAAAACAGCCTACGGTTATGTAAAAGGCTATG
CCGGAGACAACAATCTTCATATGCGCGGTGCCGAAATAGATCGGCTCGTACAGGGATGCACAGGTGTAAAACGTACAACT
GGACAGCACCCTGGCGGTATTATCGTAGTTCCGGATTATATGGATATTTATGATTTTTCACCGATCCAGTTCCCGGCAGA
TGCCACAGGTTCAGAGTGGAAAACGACTCATTTTGATTTCCACTCCATCCATGACAACCTGTTAAAACTTGATATTCTCG
GACACGATGACCCGACTGTTATTCGGATGCTTCAAGACTTAAGCGGAATAGATCCGAAAACAATTCCGACGGATGATCCT
GAAGTGATGAAGATCTTCCAGGGAACCGAATCACTCGGTGTGACTGAAGAACAGATTGGCTGTAAAACGGGCACTCTTGG
AATTCCTGAATTCGGAACCCGATTTGTCCGGCAGATGCTTGAAGATACAAAGCCGACCACTTTTTCTGAGCTCGTTCAGA
TTTCAGGCTTGTCTCACGGAACTGATGTATGGCTTGGCAATGCACAGGAGCTCATCCACAATAATATTTGTGAGCTGAGT
GAGGTTATCGGCTGCCGTGATGACATTATGGTTTATTTAATCTATCAAGGCCTTGAGCCGTCCCTTGCCTTTAAAATCAT
GGAATTCGTGCGTAAAGGAAAAGGATTAACGCCTGAATGGGAAGAAGAAATGAAAAATAACAATGTCCCAGACTGGTATA
TTGATTCCTGTAAAAAGATTAAATACATGTTCCCGAAAGCCCACGCCGCGGCATATGTCTTAATGGCAGTCCGCATTGCT
TACTTTAAAGTGCATCATGCTCTTTTGTATTATGCGGCTTATTTTACCGTTCGTGCAGATGACTTTGATATTGATACAAT
GATCAAGGGCTCTACAGCAATCAGAGCGGTAATGGAGGATATAAACGCTAAAGGACTTGATGCTTCACCGAAGGAAAAGA
ACCTTCTGACTGTTTTAGAATTAGCGCTTGAGATGTGTGAGAGAGGCTATTCATTCCAAAAAGTCGATTTATATCGCTCC
AGCGCCACAGAGTTTATTATTGACGGCAACAGTCTTATTCCGCCGTTTAACTCTATTCCAGGGTTAGGGACGAACGCTGC
TTTGAACATTGTAAAAGCTCGCGAAGAAGGCGAATTCCTCTCAAAAGAAGATTTGCAAAAGAGAGGGAAAGTATCAAAAA
CGATTTTAGAGTACTTAGATCGCCATGGCTGTCTGGAGTCACTGCCTGATCAAAACCAATTGTCACTGTTCTAA

Upstream 100 bases:

>100_bases
ACGATTTATCAAAAAACATGTTAAAATAGAAATAATAGAAGGTACCTCATTGCCTGAGGTACCTTCACTTATGATGTTTT
TAGGGAGGGATACTGTCTTA

Downstream 100 bases:

>100_bases
TATGGAAAGCAGAATTTCTCAGAAATTCTGCTTCTATGCATACATAAGCGCAAAAAGTGCCATCGTAATATTAGAGTTTC
TGTCACTTGCTTAGGTATGA

Product: DNA polymerase III PolC

Products: NA

Alternate protein names: PolIII

Number of amino acids: Translated: 1437; Mature: 1437

Protein sequence:

>1437_residues
MEQLSVNRRQFQILLQQINMTDDTFMTYFEHGEIKKLTIHKASKSWHFHFQFKSLLPFQIYDTLTTRLTQSFAHIAKVTS
SIEVQDAEVSESIVQDYWSRCIEELQGISPPIISLLNQQKPKLKGNKLIVKTKTDTEAAALKNKYSSMIQAEYRQFGFPD
LQLDAEIFVSEQEVQKFREQKLAEDQERAMQALIEMEKKDKESDEDQAPSGPLVIGYQIKDNEEIRTLDSIMDEERRITV
QGYVFDVETRELKSGRTLCIFKITDYTNSILIKMFAREKEDAALMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEIK
AKTREDSAPEGEKRVELHLHSPMSQMDAVTGIGKLVEQAKKWGHEAIALTDHAVVQSFPDAYSAAKKHGIKMIYGMEANL
VDDGVPIAYNAAHRLLEEETYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIDKFEAFANPHRPLSATIIELTGITDDML
QDAPDVVDVIRDFREWIGDDILVAHNASFDMGFLNVAYKKLLEVEKAKNPVIDTLELGRFLYPEFKNHRLNTLCKKFDIE
LTQHHRAIYDTEATAYLLLKMLKDAAEKGIQYHDELNENMGQSNAYQRSRPYHATLLAVNSTGLKNLFKLVSLSHIHYFY
RVPRIPRSQLEKYREGLLIGSACDRGEVFEGMMQKSPEEVEDIASFYDYLEVQPPEVYRHLLELELVRDEKALKEIIANI
TKLGEKLNKPVVATGNVHYLNDEDKIYRKILISSQGGANPLNRHELPKVHFRTTDEMLEAFSFLGEEKAKEIVVTNTQKV
ASLVDDIKPIKDDLYTPKIEGADEEIREMSYQRARSIYGEELPEIVEARIEKELKSIIGHGFAVIYLISHKLVKRSLDDG
YLVGSRGSVGSSLVATLTEITEVNPLPPHYVCPECQHSEFFNDGSVGSGFDLPDKTCPHCGTPLKKDGHDIPFETFLGFK
GDKVPDIDLNFSGEYQPQAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYAGDNNLHMRGAEIDRLVQGCTGVKRTT
GQHPGGIIVVPDYMDIYDFSPIQFPADATGSEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDP
EVMKIFQGTESLGVTEEQIGCKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICELS
EVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKYMFPKAHAAAYVLMAVRIA
YFKVHHALLYYAAYFTVRADDFDIDTMIKGSTAIRAVMEDINAKGLDASPKEKNLLTVLELALEMCERGYSFQKVDLYRS
SATEFIIDGNSLIPPFNSIPGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTILEYLDRHGCLESLPDQNQLSLF

Sequences:

>Translated_1437_residues
MEQLSVNRRQFQILLQQINMTDDTFMTYFEHGEIKKLTIHKASKSWHFHFQFKSLLPFQIYDTLTTRLTQSFAHIAKVTS
SIEVQDAEVSESIVQDYWSRCIEELQGISPPIISLLNQQKPKLKGNKLIVKTKTDTEAAALKNKYSSMIQAEYRQFGFPD
LQLDAEIFVSEQEVQKFREQKLAEDQERAMQALIEMEKKDKESDEDQAPSGPLVIGYQIKDNEEIRTLDSIMDEERRITV
QGYVFDVETRELKSGRTLCIFKITDYTNSILIKMFAREKEDAALMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEIK
AKTREDSAPEGEKRVELHLHSPMSQMDAVTGIGKLVEQAKKWGHEAIALTDHAVVQSFPDAYSAAKKHGIKMIYGMEANL
VDDGVPIAYNAAHRLLEEETYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIDKFEAFANPHRPLSATIIELTGITDDML
QDAPDVVDVIRDFREWIGDDILVAHNASFDMGFLNVAYKKLLEVEKAKNPVIDTLELGRFLYPEFKNHRLNTLCKKFDIE
LTQHHRAIYDTEATAYLLLKMLKDAAEKGIQYHDELNENMGQSNAYQRSRPYHATLLAVNSTGLKNLFKLVSLSHIHYFY
RVPRIPRSQLEKYREGLLIGSACDRGEVFEGMMQKSPEEVEDIASFYDYLEVQPPEVYRHLLELELVRDEKALKEIIANI
TKLGEKLNKPVVATGNVHYLNDEDKIYRKILISSQGGANPLNRHELPKVHFRTTDEMLEAFSFLGEEKAKEIVVTNTQKV
ASLVDDIKPIKDDLYTPKIEGADEEIREMSYQRARSIYGEELPEIVEARIEKELKSIIGHGFAVIYLISHKLVKRSLDDG
YLVGSRGSVGSSLVATLTEITEVNPLPPHYVCPECQHSEFFNDGSVGSGFDLPDKTCPHCGTPLKKDGHDIPFETFLGFK
GDKVPDIDLNFSGEYQPQAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYAGDNNLHMRGAEIDRLVQGCTGVKRTT
GQHPGGIIVVPDYMDIYDFSPIQFPADATGSEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDP
EVMKIFQGTESLGVTEEQIGCKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICELS
EVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKYMFPKAHAAAYVLMAVRIA
YFKVHHALLYYAAYFTVRADDFDIDTMIKGSTAIRAVMEDINAKGLDASPKEKNLLTVLELALEMCERGYSFQKVDLYRS
SATEFIIDGNSLIPPFNSIPGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTILEYLDRHGCLESLPDQNQLSLF
>Mature_1437_residues
MEQLSVNRRQFQILLQQINMTDDTFMTYFEHGEIKKLTIHKASKSWHFHFQFKSLLPFQIYDTLTTRLTQSFAHIAKVTS
SIEVQDAEVSESIVQDYWSRCIEELQGISPPIISLLNQQKPKLKGNKLIVKTKTDTEAAALKNKYSSMIQAEYRQFGFPD
LQLDAEIFVSEQEVQKFREQKLAEDQERAMQALIEMEKKDKESDEDQAPSGPLVIGYQIKDNEEIRTLDSIMDEERRITV
QGYVFDVETRELKSGRTLCIFKITDYTNSILIKMFAREKEDAALMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEIK
AKTREDSAPEGEKRVELHLHSPMSQMDAVTGIGKLVEQAKKWGHEAIALTDHAVVQSFPDAYSAAKKHGIKMIYGMEANL
VDDGVPIAYNAAHRLLEEETYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIDKFEAFANPHRPLSATIIELTGITDDML
QDAPDVVDVIRDFREWIGDDILVAHNASFDMGFLNVAYKKLLEVEKAKNPVIDTLELGRFLYPEFKNHRLNTLCKKFDIE
LTQHHRAIYDTEATAYLLLKMLKDAAEKGIQYHDELNENMGQSNAYQRSRPYHATLLAVNSTGLKNLFKLVSLSHIHYFY
RVPRIPRSQLEKYREGLLIGSACDRGEVFEGMMQKSPEEVEDIASFYDYLEVQPPEVYRHLLELELVRDEKALKEIIANI
TKLGEKLNKPVVATGNVHYLNDEDKIYRKILISSQGGANPLNRHELPKVHFRTTDEMLEAFSFLGEEKAKEIVVTNTQKV
ASLVDDIKPIKDDLYTPKIEGADEEIREMSYQRARSIYGEELPEIVEARIEKELKSIIGHGFAVIYLISHKLVKRSLDDG
YLVGSRGSVGSSLVATLTEITEVNPLPPHYVCPECQHSEFFNDGSVGSGFDLPDKTCPHCGTPLKKDGHDIPFETFLGFK
GDKVPDIDLNFSGEYQPQAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYAGDNNLHMRGAEIDRLVQGCTGVKRTT
GQHPGGIIVVPDYMDIYDFSPIQFPADATGSEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDP
EVMKIFQGTESLGVTEEQIGCKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICELS
EVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKYMFPKAHAAAYVLMAVRIA
YFKVHHALLYYAAYFTVRADDFDIDTMIKGSTAIRAVMEDINAKGLDASPKEKNLLTVLELALEMCERGYSFQKVDLYRS
SATEFIIDGNSLIPPFNSIPGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTILEYLDRHGCLESLPDQNQLSLF

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Escherichia coli, GI1786381, Length=917, Percent_Identity=22.4645583424209, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1788149, Length=176, Percent_Identity=30.6818181818182, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786409, Length=194, Percent_Identity=27.8350515463918, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO3_BACSU (P13267)

Other databases:

- EMBL:   X52116
- EMBL:   M22996
- EMBL:   AL009126
- EMBL:   S55653
- EMBL:   M33543
- EMBL:   Z18631
- PIR:   F69680
- RefSeq:   NP_389540.1
- ProteinModelPortal:   P13267
- EnsemblBacteria:   EBBACT00000002117
- GeneID:   939620
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU16580
- NMPDR:   fig|224308.1.peg.1661
- GenoList:   BSU16580
- GeneTree:   EBGT00070000031732
- HOGENOM:   HBG617116
- OMA:   WKTTHFD
- PhylomeDB:   P13267
- ProtClustDB:   PRK00448
- BioCyc:   BSUB:BSU16580-MONOMER
- BRENDA:   2.7.7.7
- GO:   GO:0005737
- HAMAP:   MF_00356
- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337
- SMART:   SM00479
- SMART:   SM00481
- TIGRFAMs:   TIGR00573
- TIGRFAMs:   TIGR01405

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB; SSF53098 RNaseH_fold

EC number: =2.7.7.7

Molecular weight: Translated: 162665; Mature: 162665

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLSVNRRQFQILLQQINMTDDTFMTYFEHGEIKKLTIHKASKSWHFHFQFKSLLPFQI
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEECCCCEEEEEEECCCCCHHH
YDTLTTRLTQSFAHIAKVTSSIEVQDAEVSESIVQDYWSRCIEELQGISPPIISLLNQQK
HHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
PKLKGNKLIVKTKTDTEAAALKNKYSSMIQAEYRQFGFPDLQLDAEIFVSEQEVQKFREQ
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHEECHHHHHHHHHH
KLAEDQERAMQALIEMEKKDKESDEDQAPSGPLVIGYQIKDNEEIRTLDSIMDEERRITV
HHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEE
QGYVFDVETRELKSGRTLCIFKITDYTNSILIKMFAREKEDAALMKSLKKGMWVKARGSI
EEEEEECCHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCC
QNDTFVRDLVMIANDVNEIKAKTREDSAPEGEKRVELHLHSPMSQMDAVTGIGKLVEQAK
CCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KWGHEAIALTDHAVVQSFPDAYSAAKKHGIKMIYGMEANLVDDGVPIAYNAAHRLLEEET
HCCCCEEEEHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEHHHHHHHHCCCC
YVVFDVETTGLSAVYDTIIELAAVKVKGGEIIDKFEAFANPHRPLSATIIELTGITDDML
EEEEEECCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHCCCCCCCEEEEEEEECCCHHHH
QDAPDVVDVIRDFREWIGDDILVAHNASFDMGFLNVAYKKLLEVEKAKNPVIDTLELGRF
HCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LYPEFKNHRLNTLCKKFDIELTQHHRAIYDTEATAYLLLKMLKDAAEKGIQYHDELNENM
HCCHHCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GQSNAYQRSRPYHATLLAVNSTGLKNLFKLVSLSHIHYFYRVPRIPRSQLEKYREGLLIG
CCCCCHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEE
SACDRGEVFEGMMQKSPEEVEDIASFYDYLEVQPPEVYRHLLELELVRDEKALKEIIANI
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TKLGEKLNKPVVATGNVHYLNDEDKIYRKILISSQGGANPLNRHELPKVHFRTTDEMLEA
HHHHHHHCCCEEEECCEEEECCHHHHHHHHHEECCCCCCCCCCCCCCCEEECCHHHHHHH
FSFLGEEKAKEIVVTNTQKVASLVDDIKPIKDDLYTPKIEGADEEIREMSYQRARSIYGE
HHHHCHHHCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
ELPEIVEARIEKELKSIIGHGFAVIYLISHKLVKRSLDDGYLVGSRGSVGSSLVATLTEI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHH
TEVNPLPPHYVCPECQHSEFFNDGSVGSGFDLPDKTCPHCGTPLKKDGHDIPFETFLGFK
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCC
GDKVPDIDLNFSGEYQPQAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYAGDNNLH
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHCCEEEEECCCCCEE
MRGAEIDRLVQGCTGVKRTTGQHPGGIIVVPDYMDIYDFSPIQFPADATGSEWKTTHFDF
ECCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCCH
HSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFQGTESLGVTEEQIG
HHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHCCCCHHHHC
CKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICELS
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHH
EVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKI
HHHCCCHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHH
KYMFPKAHAAAYVLMAVRIAYFKVHHALLYYAAYFTVRADDFDIDTMIKGSTAIRAVMED
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCHHHHHHHHHH
INAKGLDASPKEKNLLTVLELALEMCERGYSFQKVDLYRSSATEFIIDGNSLIPPFNSIP
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCEEEECCCCCCCCCCCCC
GLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTILEYLDRHGCLESLPDQNQLSLF
CCCCCHHHHEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MEQLSVNRRQFQILLQQINMTDDTFMTYFEHGEIKKLTIHKASKSWHFHFQFKSLLPFQI
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEECCCCEEEEEEECCCCCHHH
YDTLTTRLTQSFAHIAKVTSSIEVQDAEVSESIVQDYWSRCIEELQGISPPIISLLNQQK
HHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCC
PKLKGNKLIVKTKTDTEAAALKNKYSSMIQAEYRQFGFPDLQLDAEIFVSEQEVQKFREQ
CCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHEECHHHHHHHHHH
KLAEDQERAMQALIEMEKKDKESDEDQAPSGPLVIGYQIKDNEEIRTLDSIMDEERRITV
HHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEE
QGYVFDVETRELKSGRTLCIFKITDYTNSILIKMFAREKEDAALMKSLKKGMWVKARGSI
EEEEEECCHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCC
QNDTFVRDLVMIANDVNEIKAKTREDSAPEGEKRVELHLHSPMSQMDAVTGIGKLVEQAK
CCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KWGHEAIALTDHAVVQSFPDAYSAAKKHGIKMIYGMEANLVDDGVPIAYNAAHRLLEEET
HCCCCEEEEHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEHHHHHHHHCCCC
YVVFDVETTGLSAVYDTIIELAAVKVKGGEIIDKFEAFANPHRPLSATIIELTGITDDML
EEEEEECCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHCCCCCCCEEEEEEEECCCHHHH
QDAPDVVDVIRDFREWIGDDILVAHNASFDMGFLNVAYKKLLEVEKAKNPVIDTLELGRF
HCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LYPEFKNHRLNTLCKKFDIELTQHHRAIYDTEATAYLLLKMLKDAAEKGIQYHDELNENM
HCCHHCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GQSNAYQRSRPYHATLLAVNSTGLKNLFKLVSLSHIHYFYRVPRIPRSQLEKYREGLLIG
CCCCCHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEE
SACDRGEVFEGMMQKSPEEVEDIASFYDYLEVQPPEVYRHLLELELVRDEKALKEIIANI
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TKLGEKLNKPVVATGNVHYLNDEDKIYRKILISSQGGANPLNRHELPKVHFRTTDEMLEA
HHHHHHHCCCEEEECCEEEECCHHHHHHHHHEECCCCCCCCCCCCCCCEEECCHHHHHHH
FSFLGEEKAKEIVVTNTQKVASLVDDIKPIKDDLYTPKIEGADEEIREMSYQRARSIYGE
HHHHCHHHCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
ELPEIVEARIEKELKSIIGHGFAVIYLISHKLVKRSLDDGYLVGSRGSVGSSLVATLTEI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHH
TEVNPLPPHYVCPECQHSEFFNDGSVGSGFDLPDKTCPHCGTPLKKDGHDIPFETFLGFK
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCC
GDKVPDIDLNFSGEYQPQAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYAGDNNLH
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHCCEEEEECCCCCEE
MRGAEIDRLVQGCTGVKRTTGQHPGGIIVVPDYMDIYDFSPIQFPADATGSEWKTTHFDF
ECCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCCH
HSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFQGTESLGVTEEQIG
HHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHCCCCHHHHC
CKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICELS
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHH
EVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKI
HHHCCCHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHH
KYMFPKAHAAAYVLMAVRIAYFKVHHALLYYAAYFTVRADDFDIDTMIKGSTAIRAVMED
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHCCCHHHHHHHHHH
INAKGLDASPKEKNLLTVLELALEMCERGYSFQKVDLYRSSATEFIIDGNSLIPPFNSIP
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCEEEECCCCCCCCCCCCC
GLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTILEYLDRHGCLESLPDQNQLSLF
CCCCCHHHHEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1901559; 2499883; 1840638; 9384377; 7679775; 2515995; 8491709; 1312503