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The map label for this gene is sucC

Identifier: 16078672

GI number: 16078672

Start: 1680431

End: 1681588

Strand: Direct

Name: sucC

Synonym: BSU16090

Alternate gene names: 16078672

Gene position: 1680431-1681588 (Clockwise)

Preceding gene: 16078671

Following gene: 16078673

Centisome position: 39.86

GC content: 42.83

Gene sequence:

>1158_bases
ATGAATATCCATGAGTACCAGGGAAAAGAAGTCCTCAGAAAATATGGGGTATCTGTTCCTGAAGGTAAAGTGGCTTTTAC
AGCAGAAGAAGCAGTTGAGAGTGCAAAGAGCTTATCCAGCTCGGTTTATGTCGTAAAGGCTCAAATTCATGCTGGCGGTC
GAGGCAAAGCTGGTGGGGTAAAAATAGCAAAATCATTAGACGAAGTAAAAGCGTATGCCGAAGAACTATTAGGGAAGACC
CTAGTTACACATCAGACGGGTCCGGACGGCCAAGTAATAAAACGCTTACTTATTGAAGAAGGCTGCGATATTAAAAAAGA
ATATTACATCGGTCTAGTGCTTGACCGCGCCACTTCAAGAATCGTTTTAATGGCTTCTGAAGAAGGCGGAACGGAAATTG
AAGAGGTTGCGGAGAAAACACCAGAAAAAATCAAAAAAGCTGTCATTGATCCAGCTGTTGGCCTTCAAGGCTATCAAGCC
AGAGAAATTGCATTCGCTATTAATATTCCAAAAGAGCTCGTGGGAAAAGCTGCTAAATTTATGCTTGGACTATATAAAGC
GTTTGTTGAGAAAGACTGCTCAATCGCCGAAATCAATCCGCTTGTTGTGACTGGCGACGGAAATGTGATGGCGCTTGATG
CAAAATTGAATTTTGACAGCAATGCGTTGTACCGACAAAAGGACATTATGGAATACAGAGATTTGGATGAAGAAGATCCG
AAAGAAATTGAAGCGTCCAAATATGATCTAAGCTACATTTCCCTTGATGGAAATATCGGCTGTATGGTAAACGGCGCGGG
ACTTGCAATGTCTACGATGGATATTATCAAGCATTATGGAGGAGAACCGGCCAACTTCCTTGATGTGGGCGGCGGTGCAA
CCGCGGAAAAAGTCACGGAAGCATTTAAAATCATTCTTTCTGATCAAAACGTTAAAGGGATTTTTGTCAACATTTTCGGC
GGCATTATGAAATGTGATGTCATCGCAGAAGGGGTTGTTGAAGCGACTAGACAAGTTGGTTTGACATTGCCGCTTGTCGT
CCGTCTTGAAGGCACAAACGTGGATCTAGGGAAGAAAATCCTTAGTGAATCAGGATTAAACATTACATCTGCGGAATCAA
TGGCTGACGGCGCGCAGAAAATCGTATCCTTAGTTTAA

Upstream 100 bases:

>100_bases
AAAAGATTTTGCATCGAACTGTAGACAATTCTTCCAGTATTATTATAGAATGAAAGCGCAGTCTATTTTAGTTTTGTTAC
ATAAGTTAGGAGGATGGGAA

Downstream 100 bases:

>100_bases
GAAAGAATGAAAGGCAGGGGACCAAATAATGAGTGTTTTCATTAATAAAGATACAAGAGTTATTGTGCAAGGGATTACAG
GTTCTACCGCTTTATTTCAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNIHEYQGKEVLRKYGVSVPEGKVAFTAEEAVESAKSLSSSVYVVKAQIHAGGRGKAGGVKIAKSLDEVKAYAEELLGKT
LVTHQTGPDGQVIKRLLIEEGCDIKKEYYIGLVLDRATSRIVLMASEEGGTEIEEVAEKTPEKIKKAVIDPAVGLQGYQA
REIAFAINIPKELVGKAAKFMLGLYKAFVEKDCSIAEINPLVVTGDGNVMALDAKLNFDSNALYRQKDIMEYRDLDEEDP
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTEAFKIILSDQNVKGIFVNIFG
GIMKCDVIAEGVVEATRQVGLTLPLVVRLEGTNVDLGKKILSESGLNITSAESMADGAQKIVSLV

Sequences:

>Translated_385_residues
MNIHEYQGKEVLRKYGVSVPEGKVAFTAEEAVESAKSLSSSVYVVKAQIHAGGRGKAGGVKIAKSLDEVKAYAEELLGKT
LVTHQTGPDGQVIKRLLIEEGCDIKKEYYIGLVLDRATSRIVLMASEEGGTEIEEVAEKTPEKIKKAVIDPAVGLQGYQA
REIAFAINIPKELVGKAAKFMLGLYKAFVEKDCSIAEINPLVVTGDGNVMALDAKLNFDSNALYRQKDIMEYRDLDEEDP
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTEAFKIILSDQNVKGIFVNIFG
GIMKCDVIAEGVVEATRQVGLTLPLVVRLEGTNVDLGKKILSESGLNITSAESMADGAQKIVSLV
>Mature_385_residues
MNIHEYQGKEVLRKYGVSVPEGKVAFTAEEAVESAKSLSSSVYVVKAQIHAGGRGKAGGVKIAKSLDEVKAYAEELLGKT
LVTHQTGPDGQVIKRLLIEEGCDIKKEYYIGLVLDRATSRIVLMASEEGGTEIEEVAEKTPEKIKKAVIDPAVGLQGYQA
REIAFAINIPKELVGKAAKFMLGLYKAFVEKDCSIAEINPLVVTGDGNVMALDAKLNFDSNALYRQKDIMEYRDLDEEDP
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTEAFKIILSDQNVKGIFVNIFG
GIMKCDVIAEGVVEATRQVGLTLPLVVRLEGTNVDLGKKILSESGLNITSAESMADGAQKIVSLV

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=48.0818414322251, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.4751958224543, Blast_Score=328, Evalue=5e-90,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=45.9610027855153, Blast_Score=307, Evalue=1e-83,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=54.2857142857143, Blast_Score=436, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17539378, Length=392, Percent_Identity=48.7244897959184, Blast_Score=366, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=45.6410256410256, Blast_Score=335, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=45.8227848101266, Blast_Score=361, Evalue=1e-101,
Organism=Drosophila melanogaster, GI21356231, Length=391, Percent_Identity=46.0358056265985, Blast_Score=341, Evalue=5e-94,
Organism=Drosophila melanogaster, GI161078106, Length=391, Percent_Identity=45.2685421994885, Blast_Score=333, Evalue=1e-91,
Organism=Drosophila melanogaster, GI24645208, Length=391, Percent_Identity=45.2685421994885, Blast_Score=333, Evalue=1e-91,
Organism=Drosophila melanogaster, GI281361397, Length=392, Percent_Identity=45.4081632653061, Blast_Score=332, Evalue=3e-91,
Organism=Drosophila melanogaster, GI281361395, Length=392, Percent_Identity=45.4081632653061, Blast_Score=332, Evalue=3e-91,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41372; Mature: 41372

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKEVLRKYGVSVPEGKVAFTAEEAVESAKSLSSSVYVVKAQIHAGGRGKAGGV
CCCCHHCCHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCH
KIAKSLDEVKAYAEELLGKTLVTHQTGPDGQVIKRLLIEEGCDIKKEYYIGLVLDRATSR
HHHHHHHHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCE
IVLMASEEGGTEIEEVAEKTPEKIKKAVIDPAVGLQGYQAREIAFAINIPKELVGKAAKF
EEEEECCCCCCHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHH
MLGLYKAFVEKDCSIAEINPLVVTGDGNVMALDAKLNFDSNALYRQKDIMEYRDLDEEDP
HHHHHHHHHHCCCCEEECCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCC
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTE
HHHCCCEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDQNVKGIFVNIFGGIMKCDVIAEGVVEATRQVGLTLPLVVRLEGTNVDLGKKI
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHH
LSESGLNITSAESMADGAQKIVSLV
HHHCCCCEECHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQGKEVLRKYGVSVPEGKVAFTAEEAVESAKSLSSSVYVVKAQIHAGGRGKAGGV
CCCCHHCCHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCH
KIAKSLDEVKAYAEELLGKTLVTHQTGPDGQVIKRLLIEEGCDIKKEYYIGLVLDRATSR
HHHHHHHHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCE
IVLMASEEGGTEIEEVAEKTPEKIKKAVIDPAVGLQGYQAREIAFAINIPKELVGKAAKF
EEEEECCCCCCHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHH
MLGLYKAFVEKDCSIAEINPLVVTGDGNVMALDAKLNFDSNALYRQKDIMEYRDLDEEDP
HHHHHHHHHHCCCCEEECCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCC
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTE
HHHCCCEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDQNVKGIFVNIFGGIMKCDVIAEGVVEATRQVGLTLPLVVRLEGTNVDLGKKI
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHH
LSESGLNITSAESMADGAQKIVSLV
HHHCCCCEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA