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The map label for this gene is pbpH

Identifier: 16078462

GI number: 16078462

Start: 1467805

End: 1469862

Strand: Direct

Name: pbpH

Synonym: BSU13980

Alternate gene names: 16078462

Gene position: 1467805-1469862 (Clockwise)

Preceding gene: 16078460

Following gene: 16078463

Centisome position: 34.82

GC content: 40.23

Gene sequence:

>2058_bases
ATGAACCTTTTTTTCCTAGCTGTCTTTGTTCTATTCACTGCATTAATTTTTAAGCTCGGGGTTGTTCAAATTGTTGAAGG
CGAACAGCATGAAGAAGACGCTGAGAAATCAAATGCAAAAACAGCTTACTATCCTGCGCCTCGCGGGAAGATGTACGACA
GAAACCAGAAAGTTGCTGTCGACAACCAGAGCGTTCCAGAAATTGTGTATGTATCAACATCTAGCACAAAAACAGAAGAT
AAAATCAAAACAGCGAAGCGGCTTGCTTCTTTCATTCATATTGATACCGAATTTTTGAAGGAAAGGGATCTTCGTGATTA
CTGGATCGCAGCTCATCCGAAAAAAGCCGCCGCTCTGCTTAAGGAATCAGAAAGCAATCTGAAAGGAGACCAGGCTTACA
AGCTTCAAATAGAGCGTGTTCCGGATCAAGAATTAAAGGCTATTCAGCAAGATGACGAAGAAATGGAAACTGCTGCGATA
TATACAAGGTTTTCAAGCGGAAATGCTTACGAACCTCAAATCGTAAAGGCAATGAATCCAAATAAGAGCAATAGCAATGG
AAAAAACGGAGCGCTGCTTGATGAGAAGAAAAACTCCTCGCAAAGACCAAAAAATGACTTAACATATGATGAAATTTCCA
TTGTTTCTGAGCATTTAGAAGAACTTCCGGGAATCGATATCGTAAACGATTGGACACGAAAATATCCTTATGACAAAACC
CTTTATTCTGTTTTCGGGGGCGTCACGACACCTGATCAGGGCCTGCTGAGCGACCGGAAAGATTTCTACTTAACAAGAGG
CTATGCGAATAATGACAGGGTGGGAAAAAGTTATTTAGAGTATCAATATGAAGAATATTTAAATTCGCATAAAGAAAAAG
TGGAATACGTAGAAGATAATAAAGGAAATGTCGTCAGCCAAAAAACCATTGATAAGGGCAGCAGGGGATACGATCTTCAG
CTTTCTTTTGACATGGAGCTTCAGGCAAAGGTAGAAAAGATCATTGAAGAAGAAGTAAGAAACAGCCGTGCACGCGGAAA
TTACATGCTTGACAGAGCCTTTGCCGTAATGATGGACCCGAATAACGGCGATATTTTATCAATGGCAGGGAAAAAGATAG
ATTTAAAAACCAACAAAATTGAAGATTATGCGATAGGGGCATTTACCACCCAATATGAAATGGGATCAGCAGTAAAGGGG
GCCACCGTGCTAGCCGGCTATCAGGACGGGATCCCGCATTATAAATATTATATCGATGCTCCAATGCTTTTAGGAACGAA
TCTTATAAAAAAATCTTATACTAATATGGGAACCATCAATGAATTAACCGCATTGCAAAAAAGTTCAAACGTATATATGT
TCAATGTTGCCATGCATATTGCAGGCGTAACATACAAGCCGCATGGATCTCTCCCGGCTGATCAGAACGATCTACTGAAA
ATGAGAAACTATTACAGCCAGTTTGGTCTGGGAGTAAAGACAGGTATTGATCTCCCGCAGGAATCAGCCGGAATGCAAAC
CACACCTAAAACTGTAGGAGGATTAATTTTAGACTTAGCAATTGGCCAATACGATACATACACACCGCTTCAAATGGCTC
AATACATCTCAGTAATCGCCAATGGTGGCTATCGTGTTCAGCCTAGAATCGTCACAAGTATTCATAAGCCAGGAAAAAAA
GACCAGCTGGGTAAGGCGATTGAACATAGGAAACCTAAAGTACTCAATAAGATTAATAATTCAGAGAGCGATTTGAAACA
AGTACAAACAGGCATGAAATTAGTCACTTCTTCAGGGACAGCAAAAAATACGTTTACAGAAGATGTATCAGGGAAAACGG
GAACAGCGGAAACATTTTACTACGGCACGAATCGCAACTGGTGGGGGAAAAAAACATACAATCTGACTTTTGTCGGCTAT
TACCCGTCGAAAAAACCAAAAGTGGCCTTTAGTGTTGTTGTTCCATCAGTAGATGATGATGATAAGATCAATAAAATTAT
TGCCAAAAGAGCTATCCACGCCTACGCAGAGCTCGAAAAAAAACACAGTAAAAAATAA

Upstream 100 bases:

>100_bases
GTATATGTAAATATATTGAATGATTTGAGAGGGGTAACCAGAAGTGACTGAAATAGGACGTGAACCAAAGAAAAAGAGCA
AAGGAAACAGAGCAATCAGA

Downstream 100 bases:

>100_bases
AAAACAGGGTGCACAACTAAAAGATTGTGTGCCCTTTCTTTTATTCAAAAATTGACGTTCACCATAAGAATAGAAGGAGA
ATACTCATTTTCTAGCGAAT

Product: penicillin-binding enzyme for formation of rod-shaped peptidoglycan cell wall

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MNLFFLAVFVLFTALIFKLGVVQIVEGEQHEEDAEKSNAKTAYYPAPRGKMYDRNQKVAVDNQSVPEIVYVSTSSTKTED
KIKTAKRLASFIHIDTEFLKERDLRDYWIAAHPKKAAALLKESESNLKGDQAYKLQIERVPDQELKAIQQDDEEMETAAI
YTRFSSGNAYEPQIVKAMNPNKSNSNGKNGALLDEKKNSSQRPKNDLTYDEISIVSEHLEELPGIDIVNDWTRKYPYDKT
LYSVFGGVTTPDQGLLSDRKDFYLTRGYANNDRVGKSYLEYQYEEYLNSHKEKVEYVEDNKGNVVSQKTIDKGSRGYDLQ
LSFDMELQAKVEKIIEEEVRNSRARGNYMLDRAFAVMMDPNNGDILSMAGKKIDLKTNKIEDYAIGAFTTQYEMGSAVKG
ATVLAGYQDGIPHYKYYIDAPMLLGTNLIKKSYTNMGTINELTALQKSSNVYMFNVAMHIAGVTYKPHGSLPADQNDLLK
MRNYYSQFGLGVKTGIDLPQESAGMQTTPKTVGGLILDLAIGQYDTYTPLQMAQYISVIANGGYRVQPRIVTSIHKPGKK
DQLGKAIEHRKPKVLNKINNSESDLKQVQTGMKLVTSSGTAKNTFTEDVSGKTGTAETFYYGTNRNWWGKKTYNLTFVGY
YPSKKPKVAFSVVVPSVDDDDKINKIIAKRAIHAYAELEKKHSKK

Sequences:

>Translated_685_residues
MNLFFLAVFVLFTALIFKLGVVQIVEGEQHEEDAEKSNAKTAYYPAPRGKMYDRNQKVAVDNQSVPEIVYVSTSSTKTED
KIKTAKRLASFIHIDTEFLKERDLRDYWIAAHPKKAAALLKESESNLKGDQAYKLQIERVPDQELKAIQQDDEEMETAAI
YTRFSSGNAYEPQIVKAMNPNKSNSNGKNGALLDEKKNSSQRPKNDLTYDEISIVSEHLEELPGIDIVNDWTRKYPYDKT
LYSVFGGVTTPDQGLLSDRKDFYLTRGYANNDRVGKSYLEYQYEEYLNSHKEKVEYVEDNKGNVVSQKTIDKGSRGYDLQ
LSFDMELQAKVEKIIEEEVRNSRARGNYMLDRAFAVMMDPNNGDILSMAGKKIDLKTNKIEDYAIGAFTTQYEMGSAVKG
ATVLAGYQDGIPHYKYYIDAPMLLGTNLIKKSYTNMGTINELTALQKSSNVYMFNVAMHIAGVTYKPHGSLPADQNDLLK
MRNYYSQFGLGVKTGIDLPQESAGMQTTPKTVGGLILDLAIGQYDTYTPLQMAQYISVIANGGYRVQPRIVTSIHKPGKK
DQLGKAIEHRKPKVLNKINNSESDLKQVQTGMKLVTSSGTAKNTFTEDVSGKTGTAETFYYGTNRNWWGKKTYNLTFVGY
YPSKKPKVAFSVVVPSVDDDDKINKIIAKRAIHAYAELEKKHSKK
>Mature_685_residues
MNLFFLAVFVLFTALIFKLGVVQIVEGEQHEEDAEKSNAKTAYYPAPRGKMYDRNQKVAVDNQSVPEIVYVSTSSTKTED
KIKTAKRLASFIHIDTEFLKERDLRDYWIAAHPKKAAALLKESESNLKGDQAYKLQIERVPDQELKAIQQDDEEMETAAI
YTRFSSGNAYEPQIVKAMNPNKSNSNGKNGALLDEKKNSSQRPKNDLTYDEISIVSEHLEELPGIDIVNDWTRKYPYDKT
LYSVFGGVTTPDQGLLSDRKDFYLTRGYANNDRVGKSYLEYQYEEYLNSHKEKVEYVEDNKGNVVSQKTIDKGSRGYDLQ
LSFDMELQAKVEKIIEEEVRNSRARGNYMLDRAFAVMMDPNNGDILSMAGKKIDLKTNKIEDYAIGAFTTQYEMGSAVKG
ATVLAGYQDGIPHYKYYIDAPMLLGTNLIKKSYTNMGTINELTALQKSSNVYMFNVAMHIAGVTYKPHGSLPADQNDLLK
MRNYYSQFGLGVKTGIDLPQESAGMQTTPKTVGGLILDLAIGQYDTYTPLQMAQYISVIANGGYRVQPRIVTSIHKPGKK
DQLGKAIEHRKPKVLNKINNSESDLKQVQTGMKLVTSSGTAKNTFTEDVSGKTGTAETFYYGTNRNWWGKKTYNLTFVGY
YPSKKPKVAFSVVVPSVDDDDKINKIIAKRAIHAYAELEKKHSKK

Specific function: Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of the cell during vegetative growth and spore outgrowth

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PBPH_BACSU (Q796K8)

Other databases:

- EMBL:   AJ222587
- EMBL:   AL009126
- PIR:   G69864
- RefSeq:   NP_389281.1
- ProteinModelPortal:   Q796K8
- SMR:   Q796K8
- EnsemblBacteria:   EBBACT00000001913
- GeneID:   936204
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13980
- NMPDR:   fig|224308.1.peg.1400
- GenoList:   BSU13980
- GeneTree:   EBGT00070000031810
- HOGENOM:   HBG314156
- ProtClustDB:   CLSK2460911
- BioCyc:   BSUB:BSU13980-MONOMER
- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase; SSF56519 PBP_dimer; SSF56601 PBP_transp_fold

EC number: NA

Molecular weight: Translated: 77167; Mature: 77167

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: ACT_SITE 232-232

Signals:

None

Transmembrane regions:

HASH(0xec76b9c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFFLAVFVLFTALIFKLGVVQIVEGEQHEEDAEKSNAKTAYYPAPRGKMYDRNQKVAV
CCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCEEEECCCCCCCCCCCCEEEE
DNQSVPEIVYVSTSSTKTEDKIKTAKRLASFIHIDTEFLKERDLRDYWIAAHPKKAAALL
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCHHEEECCCHHHHHHH
KESESNLKGDQAYKLQIERVPDQELKAIQQDDEEMETAAIYTRFSSGNAYEPQIVKAMNP
HHHHCCCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHEEEEECCCCCCCCCEEEECCC
NKSNSNGKNGALLDEKKNSSQRPKNDLTYDEISIVSEHLEELPGIDIVNDWTRKYPYDKT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECHHHHCCCCCHH
LYSVFGGVTTPDQGLLSDRKDFYLTRGYANNDRVGKSYLEYQYEEYLNSHKEKVEYVEDN
HHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
KGNVVSQKTIDKGSRGYDLQLSFDMELQAKVEKIIEEEVRNSRARGNYMLDRAFAVMMDP
CCCEEEHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECC
NNGDILSMAGKKIDLKTNKIEDYAIGAFTTQYEMGSAVKGATVLAGYQDGIPHYKYYIDA
CCCCEEEECCCEEEEECCCCCCEEEEEEEEHHHCCCCCCCCEEEECHHCCCCCEEEEECC
PMLLGTNLIKKSYTNMGTINELTALQKSSNVYMFNVAMHIAGVTYKPHGSLPADQNDLLK
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEEEEHCCEEECCCCCCCCCHHHHHH
MRNYYSQFGLGVKTGIDLPQESAGMQTTPKTVGGLILDLAIGQYDTYTPLQMAQYISVIA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEHHHCCCCCCCHHHHHHHHHHHH
NGGYRVQPRIVTSIHKPGKKDQLGKAIEHRKPKVLNKINNSESDLKQVQTGMKLVTSSGT
CCCEEECCHHHHHHCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHEEECCCC
AKNTFTEDVSGKTGTAETFYYGTNRNWWGKKTYNLTFVGYYPSKKPKVAFSVVVPSVDDD
CCCCCHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCC
DKINKIIAKRAIHAYAELEKKHSKK
HHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MNLFFLAVFVLFTALIFKLGVVQIVEGEQHEEDAEKSNAKTAYYPAPRGKMYDRNQKVAV
CCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCEEEECCCCCCCCCCCCEEEE
DNQSVPEIVYVSTSSTKTEDKIKTAKRLASFIHIDTEFLKERDLRDYWIAAHPKKAAALL
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCHHEEECCCHHHHHHH
KESESNLKGDQAYKLQIERVPDQELKAIQQDDEEMETAAIYTRFSSGNAYEPQIVKAMNP
HHHHCCCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHHEEEEECCCCCCCCCEEEECCC
NKSNSNGKNGALLDEKKNSSQRPKNDLTYDEISIVSEHLEELPGIDIVNDWTRKYPYDKT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECHHHHCCCCCHH
LYSVFGGVTTPDQGLLSDRKDFYLTRGYANNDRVGKSYLEYQYEEYLNSHKEKVEYVEDN
HHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
KGNVVSQKTIDKGSRGYDLQLSFDMELQAKVEKIIEEEVRNSRARGNYMLDRAFAVMMDP
CCCEEEHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECC
NNGDILSMAGKKIDLKTNKIEDYAIGAFTTQYEMGSAVKGATVLAGYQDGIPHYKYYIDA
CCCCEEEECCCEEEEECCCCCCEEEEEEEEHHHCCCCCCCCEEEECHHCCCCCEEEEECC
PMLLGTNLIKKSYTNMGTINELTALQKSSNVYMFNVAMHIAGVTYKPHGSLPADQNDLLK
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEEEEHCCEEECCCCCCCCCHHHHHH
MRNYYSQFGLGVKTGIDLPQESAGMQTTPKTVGGLILDLAIGQYDTYTPLQMAQYISVIA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEHHHCCCCCCCHHHHHHHHHHHH
NGGYRVQPRIVTSIHKPGKKDQLGKAIEHRKPKVLNKINNSESDLKQVQTGMKLVTSSGT
CCCEEECCHHHHHHCCCCCHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHEEECCCC
AKNTFTEDVSGKTGTAETFYYGTNRNWWGKKTYNLTFVGYYPSKKPKVAFSVVVPSVDDD
CCCCCHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCC
DKINKIIAKRAIHAYAELEKKHSKK
HHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377