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The map label for this gene is mtnX

Identifier: 16078424

GI number: 16078424

Start: 1428275

End: 1428982

Strand: Direct

Name: mtnX

Synonym: BSU13600

Alternate gene names: 16078424

Gene position: 1428275-1428982 (Clockwise)

Preceding gene: 16078423

Following gene: 16078425

Centisome position: 33.88

GC content: 42.09

Gene sequence:

>708_bases
ATGACGACTCGAAAACCTTTTATTATTTGTGATTTTGACGGAACAATCACGATGAACGACAACATTATAAATATCATGAA
AACATTTGCTCCCCCAGAGTGGATGGCATTAAAAGACGGCGTACTTTCCAAAACGCTGTCAATCAAGGAAGGTGTCGGGC
GGATGTTCGGCCTTCTGCCCAGCAGTTTAAAAGAAGAGATTACAAGTTTTGTATTGGAAGATGCAAAAATCAGGGAAGGC
TTTCGGGAATTTGTAGCATTTATCAATGAGCACGAGATTCCGTTTTATGTCATAAGCGGTGGAATGGACTTTTTTGTATA
TCCTTTGCTTGAAGGCATTGTGGAGAAAGACCGCATTTATTGCAACCATGCTTCATTTGACAATGACTATATCCATATTG
ACTGGCCTCATTCCTGCAAGGGCACATGCAGCAATCAATGCGGGTGCTGTAAGCCGTCGGTCATCCATGAACTTTCTGAA
CCGAACCAATATATCATCATGATCGGTGATTCGGTTACAGATGTGGAGGCAGCAAAGCTGTCTGACCTATGCTTTGCAAG
GGATTATTTATTAAACGAATGCCGGGAGCAAAACCTCAATCATCTTCCGTATCAAGATTTTTATGAGATCAGAAAGGAAA
TTGAGAATGTAAAGGAGGTACAGGAATGGCTGCAAAACAAGAACGCTGGCGAGAGCTCGCTGAAGTAA

Upstream 100 bases:

>100_bases
TTATTGATGCGGTCCTAGAGGCCCAGCCGATTGATGAAAAAGCCGAACAATGCAAGGATCTTAAGCTTGCGCTAGATAAA
TGGGGAAAGGCTGAAGCCGT

Downstream 100 bases:

>100_bases
AACGGGAATTGGCAGAGAGAGATTGGTTTCCGGCGACTAGCGGCAATCTGTCAATTAAGGTTACAGATGAGCCTTTAACA
TTTCTCGTCACTGCAAGCGG

Product: 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase

Products: NA

Alternate protein names: HK-MTPenyl-1-P phosphatase

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTTRKPFIICDFDGTITMNDNIINIMKTFAPPEWMALKDGVLSKTLSIKEGVGRMFGLLPSSLKEEITSFVLEDAKIREG
FREFVAFINEHEIPFYVISGGMDFFVYPLLEGIVEKDRIYCNHASFDNDYIHIDWPHSCKGTCSNQCGCCKPSVIHELSE
PNQYIIMIGDSVTDVEAAKLSDLCFARDYLLNECREQNLNHLPYQDFYEIRKEIENVKEVQEWLQNKNAGESSLK

Sequences:

>Translated_235_residues
MTTRKPFIICDFDGTITMNDNIINIMKTFAPPEWMALKDGVLSKTLSIKEGVGRMFGLLPSSLKEEITSFVLEDAKIREG
FREFVAFINEHEIPFYVISGGMDFFVYPLLEGIVEKDRIYCNHASFDNDYIHIDWPHSCKGTCSNQCGCCKPSVIHELSE
PNQYIIMIGDSVTDVEAAKLSDLCFARDYLLNECREQNLNHLPYQDFYEIRKEIENVKEVQEWLQNKNAGESSLK
>Mature_234_residues
TTRKPFIICDFDGTITMNDNIINIMKTFAPPEWMALKDGVLSKTLSIKEGVGRMFGLLPSSLKEEITSFVLEDAKIREGF
REFVAFINEHEIPFYVISGGMDFFVYPLLEGIVEKDRIYCNHASFDNDYIHIDWPHSCKGTCSNQCGCCKPSVIHELSEP
NQYIIMIGDSVTDVEAAKLSDLCFARDYLLNECREQNLNHLPYQDFYEIRKEIENVKEVQEWLQNKNAGESSLK

Specific function: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)

COG id: COG4359

COG function: function code E; Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MtnX family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324318, Length=245, Percent_Identity=27.3469387755102, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNX_BACSU (O31667)

Other databases:

- EMBL:   AL009126
- PIR:   H69863
- RefSeq:   NP_389243.1
- PDB:   2FEA
- PDBsum:   2FEA
- ProteinModelPortal:   O31667
- SMR:   O31667
- EnsemblBacteria:   EBBACT00000004101
- GeneID:   939331
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13600
- NMPDR:   fig|224308.1.peg.1362
- GenoList:   BSU13600
- GeneTree:   EBGT00050000002067
- HOGENOM:   HBG313684
- OMA:   IAYTPFE
- PhylomeDB:   O31667
- ProtClustDB:   PRK09552
- BioCyc:   BSUB:BSU13600-MONOMER
- HAMAP:   MF_01680
- InterPro:   IPR023214
- InterPro:   IPR017718
- InterPro:   IPR006383
- InterPro:   IPR006384
- Gene3D:   G3DSA:3.40.50.1000
- TIGRFAMs:   TIGR01489
- TIGRFAMs:   TIGR01488
- TIGRFAMs:   TIGR03333

Pfam domain/function: SSF56784 SSF56784

EC number: NA

Molecular weight: Translated: 27002; Mature: 26871

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRKPFIICDFDGTITMNDNIINIMKTFAPPEWMALKDGVLSKTLSIKEGVGRMFGLLP
CCCCCCEEEEECCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCH
SSLKEEITSFVLEDAKIREGFREFVAFINEHEIPFYVISGGMDFFVYPLLEGIVEKDRIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHEE
CNHASFDNDYIHIDWPHSCKGTCSNQCGCCKPSVIHELSEPNQYIIMIGDSVTDVEAAKL
ECCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHH
SDLCFARDYLLNECREQNLNHLPYQDFYEIRKEIENVKEVQEWLQNKNAGESSLK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTRKPFIICDFDGTITMNDNIINIMKTFAPPEWMALKDGVLSKTLSIKEGVGRMFGLLP
CCCCCEEEEECCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCH
SSLKEEITSFVLEDAKIREGFREFVAFINEHEIPFYVISGGMDFFVYPLLEGIVEKDRIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHEE
CNHASFDNDYIHIDWPHSCKGTCSNQCGCCKPSVIHELSEPNQYIIMIGDSVTDVEAAKL
ECCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHH
SDLCFARDYLLNECREQNLNHLPYQDFYEIRKEIENVKEVQEWLQNKNAGESSLK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921; 14551435