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The map label for this gene is ykoH

Identifier: 16078391

GI number: 16078391

Start: 1392643

End: 1394007

Strand: Direct

Name: ykoH

Synonym: BSU13260

Alternate gene names: 16078391

Gene position: 1392643-1394007 (Clockwise)

Preceding gene: 16078390

Following gene: 16078392

Centisome position: 33.04

GC content: 46.23

Gene sequence:

>1365_bases
ATGAAGCTGAAGACCAAGATTCATCTATACACTTCGATATCACTGTTGATTTTATTAATTTTGGTTCATACCGCAGTATA
TCTCATTTTTTCGTCTGCGCTGACATCAAAGGATGCGGCCCGGCTTGCTGATGAGACGGATAACATTGCCGAAGCGCTGC
GTGCCGCTGAAACAGAAGGAGTGGCTTTGCAGGATATGCTGCAGGCCTATCTTCCGGCAAATGGCATGGTGCGTGTAGTG
AATGGTGATCAAAAAGCCGTTATGACGATCACAAAAGAAAAAGCCTATAAAGATTTTCCTCTCTCTTTTCATAGCGGCGA
AACGGCAGATGTGAGGAAACCTGACGGCAAGCTGTTTGCCGAGGCTGCTGTTCCGGTGATTTGGACCGATGGACAAGTCG
TGTCTCTTCAGCTGGTTGAAAGACTGGAGAACACAGAAGAGAGTCTGTTTCTGCTGAAAATCATCTTAATCGCTGCAAGT
GCTGCTGTCTGCATTGCTTCTTTTTTTGCAGGCAGCTTGCTAGCCCGCCGAATCATCAATCCGATCAGACGATTAATGAT
CACAATGAAAGACATACAGCGAGACAAAGAATTTAAAACGATTTCTTTAGAAGGACAGTCCAACGATGAATTGTATCAAA
TGGGGCTGACATTTAATGAAATGGCAATGATGCTGAAGGAGCACTATGATAAACAGCAGCAATTTGTTCAAGATGCTTCA
CACGAATTGAAAACCCCGCTCACTATTATAGAAAGCTACAGCAGCCTGATGAAGCGGTGGGGTGCAAAAAAGCCGGAGGT
GCTTGAGGAGTCGATAGAAGCCATTCACTCAGAAGCGGTGCATATGAAAAAACTGACCAATCAGCTTTTGGCGCTGGCCA
AAAGCCATCAAGGACTCGAGGTTGATCTGAAAACAATCGATCTGATTAAAGCGGCGCGCGCGGTTATGCAAACGCTCCAG
TCCGTTTATCAGCGTGACATATTGCTTGAAACAGATAAAGAGAGCCTGCTTGTAAAGGCAGATGAAGAACGCATCAAGCA
GCTGTTGACCATTTTGCTTGATAATGCAATAAAGTATAGTGAAAAGCCTATTGAGATGTCAGCCGGAACGAGGAATGGAC
GGCCATTTCTATCAGTGAGGGATGAAGGCATCGGAATACCTGAGGAGCATATCCCGCATTTGTTCGAACGGTTCTACCGG
GCAGATGAGGCACGAAACAGAAAAACAGGCGGAACAGGTTTAGGCCTTTCCATTGCCAAGCAAATCGCTGATGAGCATGG
CATTGAGCTGTCTGTCAAAAGCAAGCCGGGACAAGGAACAGCTGTCACCATGCAATTCAGCGAACAGAATGGGGGAGGCC
GATGA

Upstream 100 bases:

>100_bases
CGTCTACATAAGATACATCAGAAAAAAACTGGACTATCCTTACGAAAAACAGCTGATCCATACGATTCGCGGGGTCGGCT
ATGCCATTAAGGGGTAAACG

Downstream 100 bases:

>100_bases
CTAAAACAATAAAAACAGTATCTTTTGCTGCAGCAGCCATTTTAGTTGTCATCATCTGTACGTTTCTCATCATTCGGCAA
ACCCATGAGAACGTATTGTC

Product: two-component sensor histidine kinase YkoG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKLKTKIHLYTSISLLILLILVHTAVYLIFSSALTSKDAARLADETDNIAEALRAAETEGVALQDMLQAYLPANGMVRVV
NGDQKAVMTITKEKAYKDFPLSFHSGETADVRKPDGKLFAEAAVPVIWTDGQVVSLQLVERLENTEESLFLLKIILIAAS
AAVCIASFFAGSLLARRIINPIRRLMITMKDIQRDKEFKTISLEGQSNDELYQMGLTFNEMAMMLKEHYDKQQQFVQDAS
HELKTPLTIIESYSSLMKRWGAKKPEVLEESIEAIHSEAVHMKKLTNQLLALAKSHQGLEVDLKTIDLIKAARAVMQTLQ
SVYQRDILLETDKESLLVKADEERIKQLLTILLDNAIKYSEKPIEMSAGTRNGRPFLSVRDEGIGIPEEHIPHLFERFYR
ADEARNRKTGGTGLGLSIAKQIADEHGIELSVKSKPGQGTAVTMQFSEQNGGGR

Sequences:

>Translated_454_residues
MKLKTKIHLYTSISLLILLILVHTAVYLIFSSALTSKDAARLADETDNIAEALRAAETEGVALQDMLQAYLPANGMVRVV
NGDQKAVMTITKEKAYKDFPLSFHSGETADVRKPDGKLFAEAAVPVIWTDGQVVSLQLVERLENTEESLFLLKIILIAAS
AAVCIASFFAGSLLARRIINPIRRLMITMKDIQRDKEFKTISLEGQSNDELYQMGLTFNEMAMMLKEHYDKQQQFVQDAS
HELKTPLTIIESYSSLMKRWGAKKPEVLEESIEAIHSEAVHMKKLTNQLLALAKSHQGLEVDLKTIDLIKAARAVMQTLQ
SVYQRDILLETDKESLLVKADEERIKQLLTILLDNAIKYSEKPIEMSAGTRNGRPFLSVRDEGIGIPEEHIPHLFERFYR
ADEARNRKTGGTGLGLSIAKQIADEHGIELSVKSKPGQGTAVTMQFSEQNGGGR
>Mature_454_residues
MKLKTKIHLYTSISLLILLILVHTAVYLIFSSALTSKDAARLADETDNIAEALRAAETEGVALQDMLQAYLPANGMVRVV
NGDQKAVMTITKEKAYKDFPLSFHSGETADVRKPDGKLFAEAAVPVIWTDGQVVSLQLVERLENTEESLFLLKIILIAAS
AAVCIASFFAGSLLARRIINPIRRLMITMKDIQRDKEFKTISLEGQSNDELYQMGLTFNEMAMMLKEHYDKQQQFVQDAS
HELKTPLTIIESYSSLMKRWGAKKPEVLEESIEAIHSEAVHMKKLTNQLLALAKSHQGLEVDLKTIDLIKAARAVMQTLQ
SVYQRDILLETDKESLLVKADEERIKQLLTILLDNAIKYSEKPIEMSAGTRNGRPFLSVRDEGIGIPEEHIPHLFERFYR
ADEARNRKTGGTGLGLSIAKQIADEHGIELSVKSKPGQGTAVTMQFSEQNGGGR

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=28.3636363636364, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=32.15859030837, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=27.4678111587983, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786783, Length=294, Percent_Identity=27.5510204081633, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789808, Length=222, Percent_Identity=30.6306306306306, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=29.2792792792793, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789149, Length=329, Percent_Identity=25.531914893617, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=240, Percent_Identity=28.3333333333333, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=26.1224489795918, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=338, Percent_Identity=23.3727810650888, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI48994928, Length=220, Percent_Identity=25.4545454545455, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789403, Length=458, Percent_Identity=25.3275109170306, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=24.3589743589744, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=27.3127753303965, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788279, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788549, Length=208, Percent_Identity=25, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790551, Length=281, Percent_Identity=25.9786476868327, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=26.5486725663717, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787374, Length=282, Percent_Identity=23.4042553191489, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKOH_BACSU (O34638)

Other databases:

- EMBL:   AJ002571
- EMBL:   AL009126
- PIR:   D69859
- RefSeq:   NP_389209.1
- ProteinModelPortal:   O34638
- SMR:   O34638
- EnsemblBacteria:   EBBACT00000001018
- GeneID:   936458
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13260
- NMPDR:   fig|224308.1.peg.1328
- GenoList:   BSU13260
- GeneTree:   EBGT00070000031734
- HOGENOM:   HBG694527
- OMA:   TMENEAV
- ProtClustDB:   CLSK2752381
- BioCyc:   BSUB:BSU13260-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00304
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 50651; Mature: 50651

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50885 HAMP; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe73bb98)-; HASH(0xe99c094)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKTKIHLYTSISLLILLILVHTAVYLIFSSALTSKDAARLADETDNIAEALRAAETEG
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
VALQDMLQAYLPANGMVRVVNGDQKAVMTITKEKAYKDFPLSFHSGETADVRKPDGKLFA
CHHHHHHHHHCCCCCEEEEEECCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCEEH
EAAVPVIWTDGQVVSLQLVERLENTEESLFLLKIILIAASAAVCIASFFAGSLLARRIIN
HCCCCEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIRRLMITMKDIQRDKEFKTISLEGQSNDELYQMGLTFNEMAMMLKEHYDKQQQFVQDAS
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
HELKTPLTIIESYSSLMKRWGAKKPEVLEESIEAIHSEAVHMKKLTNQLLALAKSHQGLE
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VDLKTIDLIKAARAVMQTLQSVYQRDILLETDKESLLVKADEERIKQLLTILLDNAIKYS
EEHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHCC
EKPIEMSAGTRNGRPFLSVRDEGIGIPEEHIPHLFERFYRADEARNRKTGGTGLGLSIAK
CCCCEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
QIADEHGIELSVKSKPGQGTAVTMQFSEQNGGGR
HHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCH
>Mature Secondary Structure
MKLKTKIHLYTSISLLILLILVHTAVYLIFSSALTSKDAARLADETDNIAEALRAAETEG
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
VALQDMLQAYLPANGMVRVVNGDQKAVMTITKEKAYKDFPLSFHSGETADVRKPDGKLFA
CHHHHHHHHHCCCCCEEEEEECCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCEEH
EAAVPVIWTDGQVVSLQLVERLENTEESLFLLKIILIAASAAVCIASFFAGSLLARRIIN
HCCCCEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIRRLMITMKDIQRDKEFKTISLEGQSNDELYQMGLTFNEMAMMLKEHYDKQQQFVQDAS
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
HELKTPLTIIESYSSLMKRWGAKKPEVLEESIEAIHSEAVHMKKLTNQLLALAKSHQGLE
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VDLKTIDLIKAARAVMQTLQSVYQRDILLETDKESLLVKADEERIKQLLTILLDNAIKYS
EEHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHCC
EKPIEMSAGTRNGRPFLSVRDEGIGIPEEHIPHLFERFYRADEARNRKTGGTGLGLSIAK
CCCCEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
QIADEHGIELSVKSKPGQGTAVTMQFSEQNGGGR
HHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377