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The map label for this gene is appC

Identifier: 16078205

GI number: 16078205

Start: 1216210

End: 1217121

Strand: Direct

Name: appC

Synonym: BSU11400

Alternate gene names: 16078205

Gene position: 1216210-1217121 (Clockwise)

Preceding gene: 255767258

Following gene: 16078206

Centisome position: 28.85

GC content: 43.2

Gene sequence:

>912_bases
ATGTCAGAGCTGCAAACAACTCCCTCGCCGGAGATCAGGCTGAAAGAAAATATTTCGAAAAAGCCAGAAACAATGACAAA
GATTTTCTGGGAAAAATTCTCGAAAAACAAACTGGCCATTTTAGGTGCCGTTATTCTTTTTATCATTATTATGTCTGCTG
TTTTCGCCCCTTTAATTGCACCTTATCCCCAAGAGCAGCAAAGCCTGCTTGATAAATATAAGGCGCCGGGCCTTGAACAT
CTGATGGGAACGGATAAATTTGGACGTGATATTTTCAGCCGGATCCTATATGGAGCGCGTGTCTCTTTATTGGTTGGATT
TGCGTCCGTAGTCGGTTCGATTTTGATCGGAACGGTTTTAGGAGCATTAGCCGGATATTTCAGAGGAATAGTGGATGCTG
TCATTATGCGTGTAGTTGACATTGTGTTATCCATTCCTGATATTTTCTTGTTGATCACGCTGGTCACCATCTTCAAGCCG
GGTGTGGACAAATTGATTTTAATTTTCTGTCTCACAGGATGGACCACAACAGCACGATTAGTAAGGGGAGAATTCTTGTC
GCTCCGTTCAAGGGAATATGTTCTTGCTGCTAAAACAATTGGAACAAAAACGCACAAAATTATTTTTTCTCATATCCTGC
CCAATGCGTTAGGGCCGATTATCGTGTCAGCTACGCTGAAAGTTGGGTCTGTTATTCTAGCTGAATCGGCGCTAAGCTAC
TTGGGCTTTGGAATCCAGCCGCCAATCGCTAGCTGGGGGAACATGCTTCAAGACGCACAGAATTTCACAGTAATGATTCA
AGCATGGTGGTACCCGTTATTTCCCGGGCTATTTATTTTAATGACCGTTTTATGCTTCAACTTTGTCGGTGATGGCCTGC
GGGATGCGCTTGACCCGAAAAATATTAAATAA

Upstream 100 bases:

>100_bases
GTGATCTCGGCGGTTCTTGTCGTTGTCGGAAACCTCATTGCAGACATCCTTTACGCGATTGTTGATCCGCGGATCGAATA
TTAAAAGGAGGGAAACAGAG

Downstream 100 bases:

>100_bases
AAATGAATATCATATCTGTTATAAAATATCACCAAATCAGAAAAAAGCAGGTCTCCTTTAGTCAGAAAATATACAAAGAG
ATCTGCTTTTTATGATTCTT

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSELQTTPSPEIRLKENISKKPETMTKIFWEKFSKNKLAILGAVILFIIIMSAVFAPLIAPYPQEQQSLLDKYKAPGLEH
LMGTDKFGRDIFSRILYGARVSLLVGFASVVGSILIGTVLGALAGYFRGIVDAVIMRVVDIVLSIPDIFLLITLVTIFKP
GVDKLILIFCLTGWTTTARLVRGEFLSLRSREYVLAAKTIGTKTHKIIFSHILPNALGPIIVSATLKVGSVILAESALSY
LGFGIQPPIASWGNMLQDAQNFTVMIQAWWYPLFPGLFILMTVLCFNFVGDGLRDALDPKNIK

Sequences:

>Translated_303_residues
MSELQTTPSPEIRLKENISKKPETMTKIFWEKFSKNKLAILGAVILFIIIMSAVFAPLIAPYPQEQQSLLDKYKAPGLEH
LMGTDKFGRDIFSRILYGARVSLLVGFASVVGSILIGTVLGALAGYFRGIVDAVIMRVVDIVLSIPDIFLLITLVTIFKP
GVDKLILIFCLTGWTTTARLVRGEFLSLRSREYVLAAKTIGTKTHKIIFSHILPNALGPIIVSATLKVGSVILAESALSY
LGFGIQPPIASWGNMLQDAQNFTVMIQAWWYPLFPGLFILMTVLCFNFVGDGLRDALDPKNIK
>Mature_302_residues
SELQTTPSPEIRLKENISKKPETMTKIFWEKFSKNKLAILGAVILFIIIMSAVFAPLIAPYPQEQQSLLDKYKAPGLEHL
MGTDKFGRDIFSRILYGARVSLLVGFASVVGSILIGTVLGALAGYFRGIVDAVIMRVVDIVLSIPDIFLLITLVTIFKPG
VDKLILIFCLTGWTTTARLVRGEFLSLRSREYVLAAKTIGTKTHKIIFSHILPNALGPIIVSATLKVGSVILAESALSYL
GFGIQPPIASWGNMLQDAQNFTVMIQAWWYPLFPGLFILMTVLCFNFVGDGLRDALDPKNIK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787054, Length=273, Percent_Identity=40.6593406593407, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI1787760, Length=291, Percent_Identity=37.8006872852234, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1789964, Length=287, Percent_Identity=45.993031358885, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1787498, Length=292, Percent_Identity=40.0684931506849, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=36.2139917695473, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1788505, Length=227, Percent_Identity=34.8017621145374, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787549, Length=288, Percent_Identity=29.8611111111111, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APPC_BACSU (P42063)

Other databases:

- EMBL:   U20909
- EMBL:   AL009126
- PIR:   I40547
- RefSeq:   NP_389022.1
- ProteinModelPortal:   P42063
- EnsemblBacteria:   EBBACT00000001862
- GeneID:   936394
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU11400
- NMPDR:   fig|224308.1.peg.1141
- GenoList:   BSU11400
- GeneTree:   EBGT00050000000641
- HOGENOM:   HBG729429
- OMA:   KFGRDIF
- PhylomeDB:   P42063
- ProtClustDB:   CLSK887059
- BioCyc:   BSUB:BSU11400-MONOMER
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 33420; Mature: 33289

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb50d524)-; HASH(0xe49dd1c)-; HASH(0xe4cb2dc)-; HASH(0xe1a1de4)-; HASH(0xde91140)-; HASH(0xd9da67c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELQTTPSPEIRLKENISKKPETMTKIFWEKFSKNKLAILGAVILFIIIMSAVFAPLIA
CCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
PYPQEQQSLLDKYKAPGLEHLMGTDKFGRDIFSRILYGARVSLLVGFASVVGSILIGTVL
CCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALAGYFRGIVDAVIMRVVDIVLSIPDIFLLITLVTIFKPGVDKLILIFCLTGWTTTARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHH
VRGEFLSLRSREYVLAAKTIGTKTHKIIFSHILPNALGPIIVSATLKVGSVILAESALSY
HHHHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFGIQPPIASWGNMLQDAQNFTVMIQAWWYPLFPGLFILMTVLCFNFVGDGLRDALDPK
HCCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCC
NIK
CCH
>Mature Secondary Structure 
SELQTTPSPEIRLKENISKKPETMTKIFWEKFSKNKLAILGAVILFIIIMSAVFAPLIA
CCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
PYPQEQQSLLDKYKAPGLEHLMGTDKFGRDIFSRILYGARVSLLVGFASVVGSILIGTVL
CCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GALAGYFRGIVDAVIMRVVDIVLSIPDIFLLITLVTIFKPGVDKLILIFCLTGWTTTARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHH
VRGEFLSLRSREYVLAAKTIGTKTHKIIFSHILPNALGPIIVSATLKVGSVILAESALSY
HHHHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFGIQPPIASWGNMLQDAQNFTVMIQAWWYPLFPGLFILMTVLCFNFVGDGLRDALDPK
HCCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCC
NIK
CCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377