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The map label for this gene is khtT

Identifier: 16078050

GI number: 16078050

Start: 1060427

End: 1060924

Strand: Reverse

Name: khtT

Synonym: BSU09860

Alternate gene names: 16078050

Gene position: 1060924-1060427 (Counterclockwise)

Preceding gene: 16078051

Following gene: 255767226

Centisome position: 25.17

GC content: 43.37

Gene sequence:

>498_bases
TTGAATATTAAAGAAAACGATCTGCCGGGCATCGGCAAAAAGTTTGAAATCGAAACAAGAAGCCACGAAAAAATGACGAT
TATCATTCATGATGACGGAAGAAGGGAAATTTACCGGTTTAATGACCGGGACCCGGATGAGCTTCTTTCAAATATTTCAT
TGGATGATTCTGAAGCAAGGCAAATTGCAGCTATTCTCGGGGGCATGGTCTATAAACCGCAAGCTCTGGAGTCCATCGAA
ATGGCCTTCAGCGATCTTATTATTGAATGGTTTAAGGTCGAAAAAGGCGCCAAATCGATCGGACGCACACTCGGTGAGCT
TGATGTTCGCCAGAATTACGATGTCACTGTTATTGCGATTATCAAACACAACCAGGAAAAGCTCCTAAATCCCGGAGCGG
ATTCGATTATTGAAGAAAATGACACCCTTGTCCTCTCAGGTGAGAGAAAGCATCTGAAGAAACTGATTCACGATTTTCTT
TCTGGAGAGGGCGTGTGA

Upstream 100 bases:

>100_bases
CCCTGTCAAATACCAGTCTAATTACCTCCGAATATAATTTGCTCAAGTTTTATTTGTAACTCACCCCATACTGCCAACAC
TACATTCGGAGGGATTTTCA

Downstream 100 bases:

>100_bases
GCCCCGATGGACCATCTTGTATTTGAAGTCGGAACTGCACTTGTGCTTGTGGCAATCGCCAGTGTGATCGCCAATAAAAT
TAAATTTTCGATTATTCCGT

Product: K+/H+ antiporter for K+ efflux

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNIKENDLPGIGKKFEIETRSHEKMTIIIHDDGRREIYRFNDRDPDELLSNISLDDSEARQIAAILGGMVYKPQALESIE
MAFSDLIIEWFKVEKGAKSIGRTLGELDVRQNYDVTVIAIIKHNQEKLLNPGADSIIEENDTLVLSGERKHLKKLIHDFL
SGEGV

Sequences:

>Translated_165_residues
MNIKENDLPGIGKKFEIETRSHEKMTIIIHDDGRREIYRFNDRDPDELLSNISLDDSEARQIAAILGGMVYKPQALESIE
MAFSDLIIEWFKVEKGAKSIGRTLGELDVRQNYDVTVIAIIKHNQEKLLNPGADSIIEENDTLVLSGERKHLKKLIHDFL
SGEGV
>Mature_165_residues
MNIKENDLPGIGKKFEIETRSHEKMTIIIHDDGRREIYRFNDRDPDELLSNISLDDSEARQIAAILGGMVYKPQALESIE
MAFSDLIIEWFKVEKGAKSIGRTLGELDVRQNYDVTVIAIIKHNQEKLLNPGADSIIEENDTLVLSGERKHLKKLIHDFL
SGEGV

Specific function: Modulates the activity of the potassium/proton antiporter yhaU. The transporter is composed of the integral membrane protein yhaU and the regulatory protein khtT

COG id: COG0490

COG function: function code P; Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KHTT_BACSU (O07535)

Other databases:

- EMBL:   Y14080
- EMBL:   AL009126
- PIR:   F69819
- RefSeq:   NP_388867.1
- ProteinModelPortal:   O07535
- SMR:   O07535
- EnsemblBacteria:   EBBACT00000000972
- GeneID:   936284
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09860
- NMPDR:   fig|224308.1.peg.986
- GenoList:   BSU09860
- GeneTree:   EBGT00050000002675
- HOGENOM:   HBG322825
- OMA:   PGIGKKF
- ProtClustDB:   CLSK886983
- BioCyc:   BSUB:BSU09860-MONOMER
- InterPro:   IPR006037

Pfam domain/function: PF02080 TrkA_C

EC number: NA

Molecular weight: Translated: 18730; Mature: 18730

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS51202 RCK_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKENDLPGIGKKFEIETRSHEKMTIIIHDDGRREIYRFNDRDPDELLSNISLDDSEAR
CCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEECCCCCHHHHHHCCCCCCHHHH
QIAAILGGMVYKPQALESIEMAFSDLIIEWFKVEKGAKSIGRTLGELDVRQNYDVTVIAI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IKHNQEKLLNPGADSIIEENDTLVLSGERKHLKKLIHDFLSGEGV
EECCHHHHCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNIKENDLPGIGKKFEIETRSHEKMTIIIHDDGRREIYRFNDRDPDELLSNISLDDSEAR
CCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEECCCCCHHHHHHCCCCCCHHHH
QIAAILGGMVYKPQALESIEMAFSDLIIEWFKVEKGAKSIGRTLGELDVRQNYDVTVIAI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
IKHNQEKLLNPGADSIIEENDTLVLSGERKHLKKLIHDFLSGEGV
EECCHHHHCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377