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The map label for this gene is yhdP

Identifier: 16078020

GI number: 16078020

Start: 1032063

End: 1033397

Strand: Reverse

Name: yhdP

Synonym: BSU09550

Alternate gene names: 16078020

Gene position: 1033397-1032063 (Counterclockwise)

Preceding gene: 16078021

Following gene: 16078017

Centisome position: 24.51

GC content: 42.92

Gene sequence:

>1335_bases
TTGGACATAGTGAATTTGATTTTAGTTGCTGTTTTAATCGCCCTGACGGCATTTTTCGTGGCATCTGAGTTTGCCATTAT
CAGAATCAGAGGCTCACGGATCGATCAGCTGATCGCGGAAGGAAATAAAGCAGCAATAGCCGTAAAAAAAGTGACCACGC
ATCTTGATGAATATTTATCTGCGTGTCAGCTCGGAATTACATTGACTTCCATCGGATTAGGGGTTTTAGGTGAATCAACG
ATCGAAAGGCTGCTTCACCCGCTTTTCGTCCAAATGAACGTTCCAGGTTCCCTTTCACATGTCATATCGTTTATTTTTGC
GTATGCCATTATCACGTTCTTACACGTTGTTGTCGGAGAACTTGCACCTAAAACAGTCGCTATCCAAAAGGCGGAAGCAG
TGTCTATGCTGTTTGCGAAACCGCTGATTTGGTTTTACCGCATCGCGTTCCCATTCATTTGGCTTTTGAACAATTCCGCA
CGGTTATTGACCAAAGCATTTGGCCTGGAGACCGTTTCAGAAAACGAACTGGCTCACTCAGAAGAAGAGCTGCGAATCAT
TTTGTCTGAAAGCTATAAAAGCGGTGAAATCAACCAATCAGAGTTTAAATATGTGAATAAAATCTTTGAATTTGACGACA
GGCTCGCGAAAGAAATTATGATTCCGCGGACCGAAATTGTCAGCCTTCCGCATGATATCAAGATTTCTGAAATGATGGAC
ATCATTCAGATTGAAAAATATACCCGCTACCCTGTGGAAGAGGGCGATAAAGATAACATTATCGGGGTTATTAACATTAA
AGAAGTGCTGACCGCCTGCATCAGCGGTGAGGTATCTGTTGATTCCACCATTTCTCAATTCGTCAACCCTATCATTCATG
TCATTGAATCTGCGCCGATCCAAGACCTGCTTGTCAAAATGCAAAAAGAGAGGGTCCACATGGCCATTTTGTCTGATGAA
TACGGCGGTACTGCCGGGCTTGTGACGGTTGAGGACATCATTGAGGAAATTGTCGGTGAAATCCGCGACGAATTTGATAT
TGATGAAATTAGCGAAATCCGCAAAATCGGCGAAGGCCATTATATTCTTGACGGAAAAGTGTTAATTGACCAAGTAAACG
ACCTGCTAGGCATCCATTTAGAGAACGAAGAAGTCGATACAATCGGCGGCTGGTTCCTTACTCAAAAATACGATGTTGAA
AAAGATGATTCCATCATCGAAGAGGGCTGCGAATTCATCATTAATGAAATTGACGGCCACCACGTCGCATATATTGAAGT
GAAAAAGCTTCAAGAAGAAGAACTTCTGGAGACAGCTAACCAGCAGGAAGCATAA

Upstream 100 bases:

>100_bases
GCTCGCCGTGTTCCAATCATTTATGCTGCTGTTAAGTTAAAACCATTTTATCTAACAGGAGGTGTTACCTTCATTCTCAT
TGCTAGAGTGAAGGTTCTAA

Downstream 100 bases:

>100_bases
TAAGAAAAGCACCTTGTATAGGGTGCTTTTCTTATTTTCACAGTTTCAGGACAATCTCTCAGAACGCCTTATAGCTGATC
AAGTTTATTCTCTAGTTCTT

Product: transporter or sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRIDQLIAEGNKAAIAVKKVTTHLDEYLSACQLGITLTSIGLGVLGEST
IERLLHPLFVQMNVPGSLSHVISFIFAYAIITFLHVVVGELAPKTVAIQKAEAVSMLFAKPLIWFYRIAFPFIWLLNNSA
RLLTKAFGLETVSENELAHSEEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSTISQFVNPIIHVIESAPIQDLLVKMQKERVHMAILSDE
YGGTAGLVTVEDIIEEIVGEIRDEFDIDEISEIRKIGEGHYILDGKVLIDQVNDLLGIHLENEEVDTIGGWFLTQKYDVE
KDDSIIEEGCEFIINEIDGHHVAYIEVKKLQEEELLETANQQEA

Sequences:

>Translated_444_residues
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRIDQLIAEGNKAAIAVKKVTTHLDEYLSACQLGITLTSIGLGVLGEST
IERLLHPLFVQMNVPGSLSHVISFIFAYAIITFLHVVVGELAPKTVAIQKAEAVSMLFAKPLIWFYRIAFPFIWLLNNSA
RLLTKAFGLETVSENELAHSEEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSTISQFVNPIIHVIESAPIQDLLVKMQKERVHMAILSDE
YGGTAGLVTVEDIIEEIVGEIRDEFDIDEISEIRKIGEGHYILDGKVLIDQVNDLLGIHLENEEVDTIGGWFLTQKYDVE
KDDSIIEEGCEFIINEIDGHHVAYIEVKKLQEEELLETANQQEA
>Mature_444_residues
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRIDQLIAEGNKAAIAVKKVTTHLDEYLSACQLGITLTSIGLGVLGEST
IERLLHPLFVQMNVPGSLSHVISFIFAYAIITFLHVVVGELAPKTVAIQKAEAVSMLFAKPLIWFYRIAFPFIWLLNNSA
RLLTKAFGLETVSENELAHSEEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSTISQFVNPIIHVIESAPIQDLLVKMQKERVHMAILSDE
YGGTAGLVTVEDIIEEIVGEIRDEFDIDEISEIRKIGEGHYILDGKVLIDQVNDLLGIHLENEEVDTIGGWFLTQKYDVE
KDDSIIEEGCEFIINEIDGHHVAYIEVKKLQEEELLETANQQEA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=402, Percent_Identity=49.2537313432836, Blast_Score=407, Evalue=1e-113,
Organism=Escherichia coli, GI1790664, Length=433, Percent_Identity=21.7090069284065, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI145693175, Length=377, Percent_Identity=25.7294429708223, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1786879, Length=279, Percent_Identity=29.3906810035842, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082033, Length=246, Percent_Identity=22.7642276422764, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788119, Length=240, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17539402, Length=264, Percent_Identity=25.7575757575758, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHDP_BACSU (O07585)

Other databases:

- EMBL:   Y14082
- EMBL:   AL009126
- PIR:   F69826
- RefSeq:   NP_388836.1
- ProteinModelPortal:   O07585
- EnsemblBacteria:   EBBACT00000002473
- GeneID:   939280
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09550
- NMPDR:   fig|224308.1.peg.955
- GenoList:   BSU09550
- GeneTree:   EBGT00070000031941
- HOGENOM:   HBG673071
- OMA:   PLFLKLH
- ProtClustDB:   CLSK886965
- BioCyc:   BSUB:BSU09550-MONOMER
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21

EC number: NA

Molecular weight: Translated: 49856; Mature: 49856

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdfa1c8c)-; HASH(0xca14e18)-; HASH(0xdfc0738)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRIDQLIAEGNKAAIAVKKVTTHLDEYLS
CCHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
ACQLGITLTSIGLGVLGESTIERLLHPLFVQMNVPGSLSHVISFIFAYAIITFLHVVVGE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAPKTVAIQKAEAVSMLFAKPLIWFYRIAFPFIWLLNNSARLLTKAFGLETVSENELAHS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHCC
EEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
HHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHH
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSTISQFVNPIIHVIESAPI
HHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCH
QDLLVKMQKERVHMAILSDEYGGTAGLVTVEDIIEEIVGEIRDEFDIDEISEIRKIGEGH
HHHHHHHHHHHHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
YILDGKVLIDQVNDLLGIHLENEEVDTIGGWFLTQKYDVEKDDSIIEEGCEFIINEIDGH
EEEECHHHHHHHHHHHEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
HVAYIEVKKLQEEELLETANQQEA
EEEEEEHHHCCHHHHHHHCCCCCH
>Mature Secondary Structure
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRIDQLIAEGNKAAIAVKKVTTHLDEYLS
CCHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
ACQLGITLTSIGLGVLGESTIERLLHPLFVQMNVPGSLSHVISFIFAYAIITFLHVVVGE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAPKTVAIQKAEAVSMLFAKPLIWFYRIAFPFIWLLNNSARLLTKAFGLETVSENELAHS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHCC
EEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
HHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHH
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSTISQFVNPIIHVIESAPI
HHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCH
QDLLVKMQKERVHMAILSDEYGGTAGLVTVEDIIEEIVGEIRDEFDIDEISEIRKIGEGH
HHHHHHHHHHHHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
YILDGKVLIDQVNDLLGIHLENEEVDTIGGWFLTQKYDVEKDDSIIEEGCEFIINEIDGH
EEEECHHHHHHHHHHHEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
HVAYIEVKKLQEEELLETANQQEA
EEEEEEHHHCCHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377