BacMap

Definition	Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome.
Accession	NC_000964
Length	4,215,606

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The map label for this gene is yhdF

Identifier: 16078010

GI number: 16078010

Start: 1022231

End: 1023100

Strand: Direct

Name: yhdF

Synonym: BSU09450

Alternate gene names: 16078010

Gene position: 1022231-1023100 (Clockwise)

Preceding gene: 255767224

Following gene: 16078011

Centisome position: 24.25

GC content: 49.08

Gene sequence:

>870_bases
GTGAACCCAATGGACAGACAAACAGAAGGACAAGAACCGCAGCATCAGGACAGACAGCCGGGCATTGAGTCAAAAATGAA
TCCGCTGCCGCTGTCAGAGGACGAGGATTATCGAGGAAGCGGAAAACTGAAAGGAAAAGTTGCGATCATTACTGGAGGCG
ACAGCGGAATAGGGAGAGCAGCAGCTATTGCCTTTGCTAAAGAGGGGGCTGATATCTCCATTCTATACTTAGACGAGCAT
TCGGACGCAGAGGAAACACGCAAACGGATCGAAAAGGAGAATGTCCGCTGCCTGCTTATCCCGGGAGATGTTGGGGACGA
GAACCATTGTGAACAAGCTGTGCAGCAAACAGTGGACCATTTTGGTAAACTCGATATCTTAGTGAACAACGCCGCTGAAC
AGCATCCCCAGGACAGCATTCTCAATATTTCAACAGAACAGCTGGAAAAAACCTTTCGCACAAATATTTTTTCCATGTTT
CATATGACGAAGAAAGCTTTGCCTCACCTGCAAGAGGGGTGTGCCATTATTAATACGACATCGATTACCGCTTATGAAGG
GGATACGGCGTTAATTGATTATTCCAGCACAAAGGGTGCGATTGTTTCCTTTACGCGTTCCATGGCGAAGTCGCTTGCAG
ATAAAGGCATCAGAGTGAATGCGGTGGCGCCCGGTCCGATTTGGACACCGCTTATTCCGGCGACATTCCCTGAGGAAAAA
GTGAAACAGCACGGCTTGGATACCCCAATGGGAAGACCGGGACAGCCGGTTGAGCATGCAGGCGCCTATGTTCTGCTGGC
GTCTGACGAATCTTCCTATATGACAGGGCAGACCATTCATGTGAATGGCGGCCGTTTTATTTCAACGTAA

Upstream 100 bases:

>100_bases
GCCATTCCCGAGGAAGTTCTTTCATAACATATTTTGGCGTTTATTCATTTCTGTCGTGTGGTAACGTTCAGTATCAACCA
CATGTCTAGGAGTGATGAAT

Downstream 100 bases:

>100_bases
TCAACGAAAAACCAGCTCAAGAGCTGGTTTTTTGTGTGGTGAAAAATTTCAAAATAAAAAATTTGTCGATTTTTCTAACA
ATTTTGTTTTCATTTTTGCA

Product: NAD(P)-dependent dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNPMDRQTEGQEPQHQDRQPGIESKMNPLPLSEDEDYRGSGKLKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEH
SDAEETRKRIEKENVRCLLIPGDVGDENHCEQAVQQTVDHFGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMF
HMTKKALPHLQEGCAIINTTSITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIRVNAVAPGPIWTPLIPATFPEEK
VKQHGLDTPMGRPGQPVEHAGAYVLLASDESSYMTGQTIHVNGGRFIST

Sequences:

>Translated_289_residues
MNPMDRQTEGQEPQHQDRQPGIESKMNPLPLSEDEDYRGSGKLKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEH
SDAEETRKRIEKENVRCLLIPGDVGDENHCEQAVQQTVDHFGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMF
HMTKKALPHLQEGCAIINTTSITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIRVNAVAPGPIWTPLIPATFPEEK
VKQHGLDTPMGRPGQPVEHAGAYVLLASDESSYMTGQTIHVNGGRFIST
>Mature_289_residues
MNPMDRQTEGQEPQHQDRQPGIESKMNPLPLSEDEDYRGSGKLKGKVAIITGGDSGIGRAAAIAFAKEGADISILYLDEH
SDAEETRKRIEKENVRCLLIPGDVGDENHCEQAVQQTVDHFGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMF
HMTKKALPHLQEGCAIINTTSITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIRVNAVAPGPIWTPLIPATFPEEK
VKQHGLDTPMGRPGQPVEHAGAYVLLASDESSYMTGQTIHVNGGRFIST

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=33.0396475770925, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=31.9502074688797, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=29.5454545454545, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=29.7959183673469, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4758504, Length=257, Percent_Identity=30.7392996108949, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI31542939, Length=210, Percent_Identity=32.3809523809524, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=31.0483870967742, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI19923817, Length=270, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=32.6315789473684, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=28.968253968254, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI83715985, Length=257, Percent_Identity=28.4046692607004, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI210032110, Length=185, Percent_Identity=31.3513513513514, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=30.1204819277108, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=32.3863636363636, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=24.5967741935484, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7706318, Length=223, Percent_Identity=26.9058295964126, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI142976729, Length=219, Percent_Identity=26.9406392694064, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789378, Length=288, Percent_Identity=45.4861111111111, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=32.2448979591837, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=34.6303501945525, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=33.739837398374, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=33.8709677419355, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=31.5789473684211, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=31.6, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=29.7619047619048, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=29.5081967213115, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=28.8537549407115, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787526, Length=260, Percent_Identity=25.7692307692308, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=36.9230769230769, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=32.6530612244898, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=34.5381526104418, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=35.361216730038, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=35.4961832061069, Blast_Score=124, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=33.7349397590361, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=34.0909090909091, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=35.7414448669202, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=34.4827586206897, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=35.1351351351351, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=38.1679389312977, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=36.5019011406844, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=34.3511450381679, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=35.9073359073359, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=270, Percent_Identity=34.0740740740741, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=35.1145038167939, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=36.1538461538462, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=32.824427480916, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=32.156862745098, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=32.3076923076923, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=33.4586466165414, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=33.203125, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=31.7647058823529, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=30.4182509505703, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=34.2205323193916, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=30.2681992337165, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=29.0196078431373, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=30.6122448979592, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=215, Percent_Identity=29.3023255813954, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=214, Percent_Identity=28.9719626168224, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=208, Percent_Identity=30.2884615384615, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=28.4552845528455, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=26.1904761904762, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=261, Percent_Identity=29.8850574712644, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=205, Percent_Identity=30.2439024390244, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=190, Percent_Identity=24.7368421052632, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=219, Percent_Identity=29.6803652968037, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=27.3092369477912, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322861, Length=233, Percent_Identity=28.3261802575107, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=190, Percent_Identity=26.8421052631579, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=33.739837398374, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=34.8837209302326, Blast_Score=130, Evalue=8e-31,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=33.596837944664, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=34.7826086956522, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=31.7269076305221, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32.8, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.8039215686275, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=35.7692307692308, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=30.8300395256917, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281364892, Length=166, Percent_Identity=30.1204819277108, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24665243, Length=208, Percent_Identity=25.9615384615385, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331218, Length=208, Percent_Identity=25.9615384615385, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580925, Length=217, Percent_Identity=26.2672811059908, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665247, Length=209, Percent_Identity=25.8373205741627, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076933, Length=207, Percent_Identity=25.6038647342995, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584748, Length=207, Percent_Identity=25.6038647342995, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221331216, Length=209, Percent_Identity=25.8373205741627, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHDF_BACSU (O07575)

Other databases:

- EMBL:   Y14082
- EMBL:   AL009126
- PIR:   D69825
- RefSeq:   NP_388826.1
- ProteinModelPortal:   O07575
- SMR:   O07575
- EnsemblBacteria:   EBBACT00000000495
- GeneID:   939749
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09450
- NMPDR:   fig|224308.1.peg.945
- GenoList:   BSU09450
- GeneTree:   EBGT00070000031724
- HOGENOM:   HBG750976
- OMA:   VNGGRFI
- PhylomeDB:   O07575
- ProtClustDB:   CLSK886959
- BioCyc:   BSUB:BSU09450-MONOMER
- GO:   GO:0005488
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081
- PRINTS:   PR00080

Pfam domain/function: PF00106 adh_short

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31510; Mature: 31510

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 194-194 BINDING 181-181

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPMDRQTEGQEPQHQDRQPGIESKMNPLPLSEDEDYRGSGKLKGKVAIITGGDSGIGRA
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHH
AAIAFAKEGADISILYLDEHSDAEETRKRIEKENVRCLLIPGDVGDENHCEQAVQQTVDH
HHEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
FGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMFHMTKKALPHLQEGCAIINTT
HCCEEEEECCCHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
SITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIRVNAVAPGPIWTPLIPATFPEEK
EEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHH
VKQHGLDTPMGRPGQPVEHAGAYVLLASDESSYMTGQTIHVNGGRFIST
HHHCCCCCCCCCCCCCHHHCCEEEEEECCCCCEECCCEEEECCCEEECC
>Mature Secondary Structure
MNPMDRQTEGQEPQHQDRQPGIESKMNPLPLSEDEDYRGSGKLKGKVAIITGGDSGIGRA
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHH
AAIAFAKEGADISILYLDEHSDAEETRKRIEKENVRCLLIPGDVGDENHCEQAVQQTVDH
HHEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
FGKLDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMFHMTKKALPHLQEGCAIINTT
HCCEEEEECCCHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
SITAYEGDTALIDYSSTKGAIVSFTRSMAKSLADKGIRVNAVAPGPIWTPLIPATFPEEK
EEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHH
VKQHGLDTPMGRPGQPVEHAGAYVLLASDESSYMTGQTIHVNGGRFIST
HHHCCCCCCCCCCCCCHHHCCEEEEEECCCCCEECCCEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377