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The map label for this gene is prkA

Identifier: 16077962

GI number: 16077962

Start: 973156

End: 975051

Strand: Direct

Name: prkA

Synonym: BSU08970

Alternate gene names: 16077962

Gene position: 973156-975051 (Clockwise)

Preceding gene: 255767209

Following gene: 16077963

Centisome position: 23.08

GC content: 43.99

Gene sequence:

>1896_bases
ATGGATATATTAAAGAAAATTGAAAAGTACAGAGAGGAAGAGCAGCGGCTGAAATGGGAAGGAACTTTCGCCGATTATTT
GGAGATTATTAAAGAAAATCCGATGGTCGCGCAATCTGCTCATTCTCGAGTTTTTAATATGATAAAAGACAGCGGGATAG
AGGAGATTGACGGACGCAAGAAGTACAGTTTTTTTGACCGCGAGCTGTTCGGGCTTGAAGAATCTCTGGAGCGTCTTGTG
GAAGAGTATTTTCATCCGGCTGCCAAACGTCTAGATGTCAGAAAGCGGATTCTATTGCTGATGGGGCCTGTGAGCGGCGG
TAAATCCACGCTGGTCACAATGCTTAAAAAAGGTCTCGAAGCGTACACGCTGACAGATAATGGCGCTGTATATGCGATTA
AAGGCTGCCCGATGCACGAGGACCCTCTACATTTAATCCCCCATCATTTACGCGATGACTTTTACAGAGAATACGGCATT
AGAATAGAAGGAAGTCTTTCTCCTTTAAATGTCATGAGGCTGGAGGAAGAGTACGGAGGAAGAATTGAGGATGTGAAGGT
GGAGCGCATCTTCTTTTCAGAAGATAAGCGTACGGGAATTGGAACATTCAGTCCCTCTGATCCGAAATCTCAGGATATTG
CCGATTTGACGGGGAGTATTGATTTCTCAACAATCGCCGAGTACGGTTCAGAATCAGATCCGCGCGCTTATCGATTTGAC
GGAGAGCTGAATAAAGCGAACCGCGGGATGATGGAGTTTCAGGAGATGCTGAAATGTGATGAGAAATTTCTCTGGCATTT
GCTTTCCTTGACACAGGAAGGGAATTTTAAAGCTGGGCGGTTTGCGTTAATTTCTGCTGATGAGCTGATCGTGGCTCACA
CGAATGAAACGGAGTATCGCTCATTTATTTCTAATAAGAAGAATGAAGCCCTGCACTCAAGAATCATCGTGATGCCGGTT
CCTTATAATTTAAAAGTGTCTGAGGAAGAGAGAATTTATGAAAAAATGATTGCAGAAAGCGATGTGGCGGATGTTCATAT
TGCCCCGCATACGTTGAAGGTCGCCGCGATGTTCTCAATCCTTACCCGGTTAAAAGAGCCGAAGCGGTCGGATATTGATC
TGGTCAAGAAAATGAGACTGTATGATGGGGAAAGTGTGGAAGGATATAACTCTGTCGACGTTGAGGATATGAAAAAAGAA
TATAATGATGAAGGCATGAGCGGAATTGATCCGCGGTACGTGATCAACCGGATTTCTTCAACGATTATCAGAAAAAATAT
GGAATCGATTAATTCTCTCGATGTCCTTCGCTCCTTAAAAGAAGGTCTTGATCAGCACCCATCAATTTCAAGCGAGGACA
GGGAGCGGTATTTGAATTTTATCTCTGCCGCCCGCAAGGAATATGACGATATTGCGAAAAAGGAAGTTCAAAAAGCGTTT
GTTTATTCATATGAAGAATCAGCAAAAACACTTATGGACAATTACCTCGATAACGTAGAGGCCTATTGCAATAAAAACAA
GCTTCGTGATCCTTTGACAGGAGAGGAAATGAACCCTGACGAAAAGCTGATGAGATCCATCGAAGAGCAGATCGGCATTT
CGGAAAACGCCAAAAAAGCGTTCCGCGAAGAAATTTTAATCCGCATCTCGGCCTATGCGAGAAAAGGCAAGCGGTTTGAT
TACAATTCCCATGAAAGACTGCGTGAAGCTATTCAGAAAAAGCTGTTTGCTGATCTGAAGGATGTCGTTAAAATTACGAC
CTCAACAAAAACGCCGGATGAGCAGCAGCTGAAAAAGGTAAATGAAGTCGTGGCCCGTTTAATTGATGAGCACGGCTACA
ACTCGACGAGCGCCAATGAGCTGCTGAAATATGTCGGCAGCCTGCTGAACCGATAA

Upstream 100 bases:

>100_bases
TATTTTTAAGAAACCAAAGCATGTATCACGAGATGGCGGCATAGATTGTATCAAAGTACCTTATTTGCATAGTGTATCAA
ACATGATAGAGGAGGTCCTT

Downstream 100 bases:

>100_bases
GCAACGTGACCCGTCCGAATAGGGCGGGTTATTTTGTCCCATTTTCTAAATAGTTTGTCAATTAAACGTGCATATGTGCA
TATGATGAATATAAATCTTT

Product: serine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MDILKKIEKYREEEQRLKWEGTFADYLEIIKENPMVAQSAHSRVFNMIKDSGIEEIDGRKKYSFFDRELFGLEESLERLV
EEYFHPAAKRLDVRKRILLLMGPVSGGKSTLVTMLKKGLEAYTLTDNGAVYAIKGCPMHEDPLHLIPHHLRDDFYREYGI
RIEGSLSPLNVMRLEEEYGGRIEDVKVERIFFSEDKRTGIGTFSPSDPKSQDIADLTGSIDFSTIAEYGSESDPRAYRFD
GELNKANRGMMEFQEMLKCDEKFLWHLLSLTQEGNFKAGRFALISADELIVAHTNETEYRSFISNKKNEALHSRIIVMPV
PYNLKVSEEERIYEKMIAESDVADVHIAPHTLKVAAMFSILTRLKEPKRSDIDLVKKMRLYDGESVEGYNSVDVEDMKKE
YNDEGMSGIDPRYVINRISSTIIRKNMESINSLDVLRSLKEGLDQHPSISSEDRERYLNFISAARKEYDDIAKKEVQKAF
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKAFREEILIRISAYARKGKRFD
YNSHERLREAIQKKLFADLKDVVKITTSTKTPDEQQLKKVNEVVARLIDEHGYNSTSANELLKYVGSLLNR

Sequences:

>Translated_631_residues
MDILKKIEKYREEEQRLKWEGTFADYLEIIKENPMVAQSAHSRVFNMIKDSGIEEIDGRKKYSFFDRELFGLEESLERLV
EEYFHPAAKRLDVRKRILLLMGPVSGGKSTLVTMLKKGLEAYTLTDNGAVYAIKGCPMHEDPLHLIPHHLRDDFYREYGI
RIEGSLSPLNVMRLEEEYGGRIEDVKVERIFFSEDKRTGIGTFSPSDPKSQDIADLTGSIDFSTIAEYGSESDPRAYRFD
GELNKANRGMMEFQEMLKCDEKFLWHLLSLTQEGNFKAGRFALISADELIVAHTNETEYRSFISNKKNEALHSRIIVMPV
PYNLKVSEEERIYEKMIAESDVADVHIAPHTLKVAAMFSILTRLKEPKRSDIDLVKKMRLYDGESVEGYNSVDVEDMKKE
YNDEGMSGIDPRYVINRISSTIIRKNMESINSLDVLRSLKEGLDQHPSISSEDRERYLNFISAARKEYDDIAKKEVQKAF
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKAFREEILIRISAYARKGKRFD
YNSHERLREAIQKKLFADLKDVVKITTSTKTPDEQQLKKVNEVVARLIDEHGYNSTSANELLKYVGSLLNR
>Mature_631_residues
MDILKKIEKYREEEQRLKWEGTFADYLEIIKENPMVAQSAHSRVFNMIKDSGIEEIDGRKKYSFFDRELFGLEESLERLV
EEYFHPAAKRLDVRKRILLLMGPVSGGKSTLVTMLKKGLEAYTLTDNGAVYAIKGCPMHEDPLHLIPHHLRDDFYREYGI
RIEGSLSPLNVMRLEEEYGGRIEDVKVERIFFSEDKRTGIGTFSPSDPKSQDIADLTGSIDFSTIAEYGSESDPRAYRFD
GELNKANRGMMEFQEMLKCDEKFLWHLLSLTQEGNFKAGRFALISADELIVAHTNETEYRSFISNKKNEALHSRIIVMPV
PYNLKVSEEERIYEKMIAESDVADVHIAPHTLKVAAMFSILTRLKEPKRSDIDLVKKMRLYDGESVEGYNSVDVEDMKKE
YNDEGMSGIDPRYVINRISSTIIRKNMESINSLDVLRSLKEGLDQHPSISSEDRERYLNFISAARKEYDDIAKKEVQKAF
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKAFREEILIRISAYARKGKRFD
YNSHERLREAIQKKLFADLKDVVKITTSTKTPDEQQLKKVNEVVARLIDEHGYNSTSANELLKYVGSLLNR

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family

Homologues:

Organism=Escherichia coli, GI1788083, Length=591, Percent_Identity=33.8409475465313, Blast_Score=281, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRKA_BACSU (P39134)

Other databases:

- EMBL:   X79388
- EMBL:   AL009126
- PIR:   JC4602
- RefSeq:   NP_388778.1
- ProteinModelPortal:   P39134
- SMR:   P39134
- EnsemblBacteria:   EBBACT00000001253
- GeneID:   939250
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU08970
- NMPDR:   fig|224308.1.peg.897
- GenoList:   BSU08970
- GeneTree:   EBGT00050000001259
- HOGENOM:   HBG309032
- OMA:   PRYAEFI
- PhylomeDB:   P39134
- ProtClustDB:   CLSK872910
- BioCyc:   BSUB:BSU08970-MONOMER
- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230
- PIRSF:   PIRSF000549
- SMART:   SM00763

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA

EC number: NA

Molecular weight: Translated: 72889; Mature: 72889

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILKKIEKYREEEQRLKWEGTFADYLEIIKENPMVAQSAHSRVFNMIKDSGIEEIDGRK
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCCC
KYSFFDRELFGLEESLERLVEEYFHPAAKRLDVRKRILLLMGPVSGGKSTLVTMLKKGLE
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCC
AYTLTDNGAVYAIKGCPMHEDPLHLIPHHLRDDFYREYGIRIEGSLSPLNVMRLEEEYGG
EEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCHHHHEEHHHHCC
RIEDVKVERIFFSEDKRTGIGTFSPSDPKSQDIADLTGSIDFSTIAEYGSESDPRAYRFD
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCEEEEC
GELNKANRGMMEFQEMLKCDEKFLWHLLSLTQEGNFKAGRFALISADELIVAHTNETEYR
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCHHHH
SFISNKKNEALHSRIIVMPVPYNLKVSEEERIYEKMIAESDVADVHIAPHTLKVAAMFSI
HHHHCCHHHHHHCEEEEEECCCCCEECHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
LTRLKEPKRSDIDLVKKMRLYDGESVEGYNSVDVEDMKKEYNDEGMSGIDPRYVINRISS
HHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHH
TIIRKNMESINSLDVLRSLKEGLDQHPSISSEDRERYLNFISAARKEYDDIAKKEVQKAF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKA
HHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
FREEILIRISAYARKGKRFDYNSHERLREAIQKKLFADLKDVVKITTSTKTPDEQQLKKV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
NEVVARLIDEHGYNSTSANELLKYVGSLLNR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDILKKIEKYREEEQRLKWEGTFADYLEIIKENPMVAQSAHSRVFNMIKDSGIEEIDGRK
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCCC
KYSFFDRELFGLEESLERLVEEYFHPAAKRLDVRKRILLLMGPVSGGKSTLVTMLKKGLE
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCC
AYTLTDNGAVYAIKGCPMHEDPLHLIPHHLRDDFYREYGIRIEGSLSPLNVMRLEEEYGG
EEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCHHHHEEHHHHCC
RIEDVKVERIFFSEDKRTGIGTFSPSDPKSQDIADLTGSIDFSTIAEYGSESDPRAYRFD
CCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCEEEEC
GELNKANRGMMEFQEMLKCDEKFLWHLLSLTQEGNFKAGRFALISADELIVAHTNETEYR
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCHHHH
SFISNKKNEALHSRIIVMPVPYNLKVSEEERIYEKMIAESDVADVHIAPHTLKVAAMFSI
HHHHCCHHHHHHCEEEEEECCCCCEECHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
LTRLKEPKRSDIDLVKKMRLYDGESVEGYNSVDVEDMKKEYNDEGMSGIDPRYVINRISS
HHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHH
TIIRKNMESINSLDVLRSLKEGLDQHPSISSEDRERYLNFISAARKEYDDIAKKEVQKAF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKA
HHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
FREEILIRISAYARKGKRFDYNSHERLREAIQKKLFADLKDVVKITTSTKTPDEQQLKKV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
NEVVARLIDEHGYNSTSANELLKYVGSLLNR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377