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The map label for this gene is acoR

Identifier: 16077877

GI number: 16077877

Start: 883758

End: 885575

Strand: Direct

Name: acoR

Synonym: BSU08100

Alternate gene names: 16077877

Gene position: 883758-885575 (Clockwise)

Preceding gene: 16077876

Following gene: 16077878

Centisome position: 20.96

GC content: 49.78

Gene sequence:

>1818_bases
ATGAATTCGGTCCCAAACGATTTGCAAACCTGGAAACGTTTTGTGAAAGACGGTGTGCTTGACGAAGCCCGATTAAGAAA
ACGGATTGCAGAGTCATGGCATCGCTGCAAAAAAGCTGAGGTCAATCCTTATTTAGAAAAAGGCCCGAAGGTTTTACAGC
AAACGGAGCTGGATCAGCAGTCAAAAAAACATTCATTCTTCTTGACGACCGCAAAGCCTTACCTCGAAAAACTGCTGCCT
GCCATAAAAGAAATGGAAATGATGGCGCTGTTAATTGATTCAGACGGTGTTGTTCTGGCATTGGACGGCCATCCGCGCGC
GCTCTATGAAGCCAAACGCATCAATTTCGTCGAAGGGGCATGCTGGACAGAAACGGCTGTCGGAACAAATGCGATTGGCA
CGGCGCTCCACATCAGCGAGCCGGTTGCAATACAAGGATCAGAGCATTACTCTATCGCTTCCCATCTTTGGAACTGTTCA
GCTGCTCCGATTCACCATGAGGATGGCAGCCTTGCGGGTGTAATTGACATATCATGCCCGGCGGCAGGCGCGCATCCTCA
TATGCTTGGTATTGCCACGGCGATTGCCTATGCCGCTGAACGGGAACTCGCAGCTAAAAGCCGTGAGAAAGAGCTGGAGC
TGATCAGCCGTTTTGGGGAGAGAGCTGCATCCAGTGTGCCGATGGTGCTCTGTAATACCAAGCAGCACATCATCAGTGCG
AGCATGCCGATTCGAACCTCAATGCCGGATTGGCAGGGCCGGCACCTGTACGAGTTGAAGGAACGGGGCTATTCAATCGA
AAATGCTGTCACCATAGGAGATGGCGGCACTTGTTTTTATCTTTCGGAACAAAAGAAAAAGAAGGCGTTTCGATTCAATG
GAGTGATCGGGCAAAGCGGCCGATCGCAAGCGATGCTGATGCACCTTGAACGAGCAGCTGCGACGGATGCATCGGTCTGT
TTGTCGGGTGAAACGGGTACGGGGAAGGAGGTCGCGGCTCGCGCGCTTCATGAGAACAGTGAGAGACGGCACGGTCCGTT
TGTTGCTGTCAATTGCGGAGCGATTCCGTCTGATTTGATTGAAAGCGAACTGTTCGGATATGCAGAGGGCGCTTTTACGG
GAGCGAAACGAAATGGCTATAAAGGCGCCTTTCAAAAAGCGAATCAAGGCACATTATTTTTAGATGAAATCGGAGAAATT
TCCCACTCGATGCAGGTTGCACTTTTACGGGTGCTTCAGGAACGCAAGATAACGCCAATCGGCGGGACGAAAGAAATTCC
GGTTGATATCAGAGTTATTGCCGCCACACATTGTGATTTACGCGAGCTTGCCGAAAACGGAAAAATCAGAGAGGACTTGT
TTTACCGTCTTCATGTCTATCCAATTGAACTCCCTCCATTACGCGATCGCACCGAGGATATCCCGGATCTCTTTGAGTAC
TACAAACAGAAGAATCATTGGCCAGGCGATCTTCCTTCTGATTTTTGTAATGTGCTGAAGCAATGGAAGTGGCCGGGGAA
TATCCGCGAGCTGTTTAATGTGTTTGAACGTCTTTCTATCAGATTTCCGGACGGCCGGCTGAGAGATGAATCGCTTCCCG
CTTTACTGGAAGCCGCTGGATTGCCGGCCAGCTCTGCAGAAAAAAAGCCGGCTGCTGCCGGCGTGCTTACTTTTCGTGAG
CAAATCCAAAAGGATATGATGATCAAAGCGCTTGAATCTGCAAAAGGAAACGTCTCTCAAGCCGCAAAAATCAGCGGGAT
CCCCCGAAGCACTTTCTACAAACGCCTGAAAAAATTCAACTTGTCCGCTGAATCATAA

Upstream 100 bases:

>100_bases
GCGCATGGATATAAGGCGCCTGCTTTTTTATTGTTGAAAGCGCTTTATTTTTCCCCTACAATAGATGAAAACGGCGTGTA
AGGGAGGAGCGATCAAGGAA

Downstream 100 bases:

>100_bases
AGCATACTTCCTTCAGGAAATGGAAACGTTATGTATTGAAGGAGGGTGTTACGATGAATATTCAAAGGGCGAAAGAAATT
GTAGAATCTCCCGACATGAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MNSVPNDLQTWKRFVKDGVLDEARLRKRIAESWHRCKKAEVNPYLEKGPKVLQQTELDQQSKKHSFFLTTAKPYLEKLLP
AIKEMEMMALLIDSDGVVLALDGHPRALYEAKRINFVEGACWTETAVGTNAIGTALHISEPVAIQGSEHYSIASHLWNCS
AAPIHHEDGSLAGVIDISCPAAGAHPHMLGIATAIAYAAERELAAKSREKELELISRFGERAASSVPMVLCNTKQHIISA
SMPIRTSMPDWQGRHLYELKERGYSIENAVTIGDGGTCFYLSEQKKKKAFRFNGVIGQSGRSQAMLMHLERAAATDASVC
LSGETGTGKEVAARALHENSERRHGPFVAVNCGAIPSDLIESELFGYAEGAFTGAKRNGYKGAFQKANQGTLFLDEIGEI
SHSMQVALLRVLQERKITPIGGTKEIPVDIRVIAATHCDLRELAENGKIREDLFYRLHVYPIELPPLRDRTEDIPDLFEY
YKQKNHWPGDLPSDFCNVLKQWKWPGNIRELFNVFERLSIRFPDGRLRDESLPALLEAAGLPASSAEKKPAAAGVLTFRE
QIQKDMMIKALESAKGNVSQAAKISGIPRSTFYKRLKKFNLSAES

Sequences:

>Translated_605_residues
MNSVPNDLQTWKRFVKDGVLDEARLRKRIAESWHRCKKAEVNPYLEKGPKVLQQTELDQQSKKHSFFLTTAKPYLEKLLP
AIKEMEMMALLIDSDGVVLALDGHPRALYEAKRINFVEGACWTETAVGTNAIGTALHISEPVAIQGSEHYSIASHLWNCS
AAPIHHEDGSLAGVIDISCPAAGAHPHMLGIATAIAYAAERELAAKSREKELELISRFGERAASSVPMVLCNTKQHIISA
SMPIRTSMPDWQGRHLYELKERGYSIENAVTIGDGGTCFYLSEQKKKKAFRFNGVIGQSGRSQAMLMHLERAAATDASVC
LSGETGTGKEVAARALHENSERRHGPFVAVNCGAIPSDLIESELFGYAEGAFTGAKRNGYKGAFQKANQGTLFLDEIGEI
SHSMQVALLRVLQERKITPIGGTKEIPVDIRVIAATHCDLRELAENGKIREDLFYRLHVYPIELPPLRDRTEDIPDLFEY
YKQKNHWPGDLPSDFCNVLKQWKWPGNIRELFNVFERLSIRFPDGRLRDESLPALLEAAGLPASSAEKKPAAAGVLTFRE
QIQKDMMIKALESAKGNVSQAAKISGIPRSTFYKRLKKFNLSAES
>Mature_605_residues
MNSVPNDLQTWKRFVKDGVLDEARLRKRIAESWHRCKKAEVNPYLEKGPKVLQQTELDQQSKKHSFFLTTAKPYLEKLLP
AIKEMEMMALLIDSDGVVLALDGHPRALYEAKRINFVEGACWTETAVGTNAIGTALHISEPVAIQGSEHYSIASHLWNCS
AAPIHHEDGSLAGVIDISCPAAGAHPHMLGIATAIAYAAERELAAKSREKELELISRFGERAASSVPMVLCNTKQHIISA
SMPIRTSMPDWQGRHLYELKERGYSIENAVTIGDGGTCFYLSEQKKKKAFRFNGVIGQSGRSQAMLMHLERAAATDASVC
LSGETGTGKEVAARALHENSERRHGPFVAVNCGAIPSDLIESELFGYAEGAFTGAKRNGYKGAFQKANQGTLFLDEIGEI
SHSMQVALLRVLQERKITPIGGTKEIPVDIRVIAATHCDLRELAENGKIREDLFYRLHVYPIELPPLRDRTEDIPDLFEY
YKQKNHWPGDLPSDFCNVLKQWKWPGNIRELFNVFERLSIRFPDGRLRDESLPALLEAAGLPASSAEKKPAAAGVLTFRE
QIQKDMMIKALESAKGNVSQAAKISGIPRSTFYKRLKKFNLSAES

Specific function: Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain

Homologues:

Organism=Escherichia coli, GI1789233, Length=306, Percent_Identity=45.4248366013072, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI87082117, Length=329, Percent_Identity=42.5531914893617, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1788550, Length=388, Percent_Identity=37.1134020618557, Blast_Score=242, Evalue=6e-65,
Organism=Escherichia coli, GI1788905, Length=362, Percent_Identity=39.2265193370166, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1786524, Length=327, Percent_Identity=41.5902140672783, Blast_Score=233, Evalue=4e-62,
Organism=Escherichia coli, GI1790437, Length=312, Percent_Identity=40.0641025641026, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789087, Length=329, Percent_Identity=37.9939209726444, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1790299, Length=365, Percent_Identity=34.2465753424658, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI87082152, Length=327, Percent_Identity=37.3088685015291, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI87081858, Length=639, Percent_Identity=25.6651017214397, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI87081872, Length=325, Percent_Identity=34.1538461538462, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1787583, Length=246, Percent_Identity=38.2113821138211, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1789828, Length=328, Percent_Identity=32.3170731707317, Blast_Score=148, Evalue=8e-37,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): ACOR_BACSU (O31551)

Other databases:

- EMBL:   D78509
- EMBL:   AL009126
- EMBL:   AF006075
- PIR:   H69581
- RefSeq:   NP_388691.1
- HSSP:   P25852
- ProteinModelPortal:   O31551
- SMR:   O31551
- EnsemblBacteria:   EBBACT00000001940
- GeneID:   936148
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU08100
- NMPDR:   fig|224308.1.peg.810
- GenoList:   BSU08100
- GeneTree:   EBGT00070000031868
- HOGENOM:   HBG740884
- PhylomeDB:   O31551
- ProtClustDB:   CLSK873142
- BioCyc:   BSUB:BSU08100-MONOMER
- GO:   GO:0005622
- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- PRINTS:   PR01590
- SMART:   SM00382

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 67161; Mature: 67161

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00675 SIGMA54_INTERACT_1; PS00676 SIGMA54_INTERACT_2; PS00688 SIGMA54_INTERACT_3; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVPNDLQTWKRFVKDGVLDEARLRKRIAESWHRCKKAEVNPYLEKGPKVLQQTELDQQ
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHH
SKKHSFFLTTAKPYLEKLLPAIKEMEMMALLIDSDGVVLALDGHPRALYEAKRINFVEGA
HCCCEEEEEEHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCHHHHHHHHCCEECCC
CWTETAVGTNAIGTALHISEPVAIQGSEHYSIASHLWNCSAAPIHHEDGSLAGVIDISCP
CCCCCCCCCCCCCCEEECCCCEEECCCCCHHHHHHHCCCCCCCEECCCCCEEEEEEEECC
AAGAHPHMLGIATAIAYAAERELAAKSREKELELISRFGERAASSVPMVLCNTKQHIISA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCC
SMPIRTSMPDWQGRHLYELKERGYSIENAVTIGDGGTCFYLSEQKKKKAFRFNGVIGQSG
CCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCEEEEECCHHHHHHHHCCCEECCCC
RSQAMLMHLERAAATDASVCLSGETGTGKEVAARALHENSERRHGPFVAVNCGAIPSDLI
CCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHH
ESELFGYAEGAFTGAKRNGYKGAFQKANQGTLFLDEIGEISHSMQVALLRVLQERKITPI
HHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCC
GGTKEIPVDIRVIAATHCDLRELAENGKIREDLFYRLHVYPIELPPLRDRTEDIPDLFEY
CCCCCCCEEEEEEEECCCCHHHHHHCCCHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHH
YKQKNHWPGDLPSDFCNVLKQWKWPGNIRELFNVFERLSIRFPDGRLRDESLPALLEAAG
HHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHCC
LPASSAEKKPAAAGVLTFREQIQKDMMIKALESAKGNVSQAAKISGIPRSTFYKRLKKFN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCC
LSAES
CCCCC
>Mature Secondary Structure
MNSVPNDLQTWKRFVKDGVLDEARLRKRIAESWHRCKKAEVNPYLEKGPKVLQQTELDQQ
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHH
SKKHSFFLTTAKPYLEKLLPAIKEMEMMALLIDSDGVVLALDGHPRALYEAKRINFVEGA
HCCCEEEEEEHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCHHHHHHHHCCEECCC
CWTETAVGTNAIGTALHISEPVAIQGSEHYSIASHLWNCSAAPIHHEDGSLAGVIDISCP
CCCCCCCCCCCCCCEEECCCCEEECCCCCHHHHHHHCCCCCCCEECCCCCEEEEEEEECC
AAGAHPHMLGIATAIAYAAERELAAKSREKELELISRFGERAASSVPMVLCNTKQHIISA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCC
SMPIRTSMPDWQGRHLYELKERGYSIENAVTIGDGGTCFYLSEQKKKKAFRFNGVIGQSG
CCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCEEEEECCHHHHHHHHCCCEECCCC
RSQAMLMHLERAAATDASVCLSGETGTGKEVAARALHENSERRHGPFVAVNCGAIPSDLI
CCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHH
ESELFGYAEGAFTGAKRNGYKGAFQKANQGTLFLDEIGEISHSMQVALLRVLQERKITPI
HHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCC
GGTKEIPVDIRVIAATHCDLRELAENGKIREDLFYRLHVYPIELPPLRDRTEDIPDLFEY
CCCCCCCEEEEEEEECCCCHHHHHHCCCHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHH
YKQKNHWPGDLPSDFCNVLKQWKWPGNIRELFNVFERLSIRFPDGRLRDESLPALLEAAG
HHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHCC
LPASSAEKKPAAAGVLTFREQIQKDMMIKALESAKGNVSQAAKISGIPRSTFYKRLKKFN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCC
LSAES
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 10368162