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The map label for this gene is degS [H]

Identifier: 159901407

GI number: 159901407

Start: 6233203

End: 6234756

Strand: Reverse

Name: degS [H]

Synonym: Haur_4896

Alternate gene names: 159901407

Gene position: 6234756-6233203 (Counterclockwise)

Preceding gene: 159901408

Following gene: 159901406

Centisome position: 98.24

GC content: 50.84

Gene sequence:

>1554_bases
ATGATGCACCCAGAGCCAATCACAATTGATCAACAAACCCCTCAAGATCGCGTTCACAACCAAAGTTTATTGTGGTCGGG
CGTTATTGCCGCCTTGGTAGCCTGTGGTGTGCCACCAATTATTGGATTGAGTGATGGCAGTCTGCGTGGCGTGAATTTGG
TTATTTATTTAGGCGCAGCCATTGGTTATATTGGCTTGAAAAGTGTTTTTTGGTTTGAAACACCACTTTGTAACCGTTTT
CGCCGCAATCCACAACTGTTAATTAGTGTGGTTTTTGGGCTGGCGGCCTTGATGCAACTGCTTAGCCGCGATTTTACGAC
CCAACCAATTGCCTTTATGGTTCCAATGGTCTTTATCGCCGGAACCTATCCCTTACCCAAAACCCTGATTATTGCTGGCT
TAATTGCAATCTTGATGAGTGGCAGTTTTATTGCCGCAGGCTTGCCACTAACCAGCGCTGGTTTATCAGCCTTATCGAGC
CAGATTGTATTGCTCCTGTTTGTTACGCTCTTCGGTTATGTCACCAACCAATCGGTGCTCACCCGCCAAAAAGTCGAGCA
ACTCGCCCAAGAATTGGCGCAAGAACGCGATTATTTACAACAGCTCAGTGCGATCACCGCCGCATTATCCAGCGAAGTTC
AATTAGCTCGCGTTTTAGCCCAAGTAGCTGAGGCAGGCCGCAGTTTGGCCAATGCCCAAGCAGTTACGGTAGCCCTGCTC
GAAGATCCAGAATGGCGGATCGTTGCCAGCGTTGGTAGTCCTGATACAAATTTACCAAGCCTTGAGATTATGCTCCACGC
CAAAGGTGAAACAATTGGCCGTTTAAATTATTGGAGTATCCAGCCAACCAATGCAGCCTTGCGCCAGGCCTTACAACCAT
TTGCCGATGCCGCAGCAATGGCAATTTACAATGCCCAACTCTACGAACAAGCGCGTTTCTCGGCAACCTTGGCTGAACGC
AACCGCCTCGCCCGCGATTTTCACGATACCTTGGCCCAGCAACTAACCGGCTTGCGCTTACAAATTGAGGCTGGCATGCG
CAACCTCCATCAGCCTGAAAAAGCCCAACTACGCTTGCAAAAAGCTTATGATTTGGCCTTGGCAGCCTTGCACGATTTAC
GGCGCAGCGTCTGGAATTTATCAGCGCCAGCGATTGATGGGCGGGTGCTCAGCGATGTTTTGGCCGAATTGGTTGATACG
TTCCATCAGCGCACCAATATTCAAAGCCAATATAGCCACGATGGTCAAGAGCTTACACTGCCCAGCGATGTGGCGATTCA
GGTATTGCGCGTGGTCAACGAGGCCTTGAGCAATGTTGAAAAGCATGCCCAAGCCAAGCATGTGGCGATTCGCTCAACCG
TCGCCGCCGGCCAGCTGCAAATCACGGTCAGCGATGATGGCCAAGGTTTTGAACTAGCCGCTGTGCAACAAACCGCCAGC
GGTGGCTTTGGCCTGACCAGCATGCGCGAACGAACTCAACTCATCCAAGGCTCGCTCTCGATTCAAAGCCAGCCAAGCGC
TGGTACGTTGCTGACGCTGTGTTTGCCGTTGTAA

Upstream 100 bases:

>100_bases
CAACTAGGCTCAATAATTATCAAATAACGATTGGCTTTTAGCTGGGCGCTAGAAGCCAACGATGCTATAGTATGAGCAGA
TTTAGGTGAGTAGCTGGTTT

Downstream 100 bases:

>100_bases
ACGCTTGGGGGTCGGGGATTGGTTGTCGGGGGCTGGGGTTAGTTTTAATCACGAAGAACACGAAGATGCACGAAGGATCG
GAACCACGAAGCACGCGAAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MMHPEPITIDQQTPQDRVHNQSLLWSGVIAALVACGVPPIIGLSDGSLRGVNLVIYLGAAIGYIGLKSVFWFETPLCNRF
RRNPQLLISVVFGLAALMQLLSRDFTTQPIAFMVPMVFIAGTYPLPKTLIIAGLIAILMSGSFIAAGLPLTSAGLSALSS
QIVLLLFVTLFGYVTNQSVLTRQKVEQLAQELAQERDYLQQLSAITAALSSEVQLARVLAQVAEAGRSLANAQAVTVALL
EDPEWRIVASVGSPDTNLPSLEIMLHAKGETIGRLNYWSIQPTNAALRQALQPFADAAAMAIYNAQLYEQARFSATLAER
NRLARDFHDTLAQQLTGLRLQIEAGMRNLHQPEKAQLRLQKAYDLALAALHDLRRSVWNLSAPAIDGRVLSDVLAELVDT
FHQRTNIQSQYSHDGQELTLPSDVAIQVLRVVNEALSNVEKHAQAKHVAIRSTVAAGQLQITVSDDGQGFELAAVQQTAS
GGFGLTSMRERTQLIQGSLSIQSQPSAGTLLTLCLPL

Sequences:

>Translated_517_residues
MMHPEPITIDQQTPQDRVHNQSLLWSGVIAALVACGVPPIIGLSDGSLRGVNLVIYLGAAIGYIGLKSVFWFETPLCNRF
RRNPQLLISVVFGLAALMQLLSRDFTTQPIAFMVPMVFIAGTYPLPKTLIIAGLIAILMSGSFIAAGLPLTSAGLSALSS
QIVLLLFVTLFGYVTNQSVLTRQKVEQLAQELAQERDYLQQLSAITAALSSEVQLARVLAQVAEAGRSLANAQAVTVALL
EDPEWRIVASVGSPDTNLPSLEIMLHAKGETIGRLNYWSIQPTNAALRQALQPFADAAAMAIYNAQLYEQARFSATLAER
NRLARDFHDTLAQQLTGLRLQIEAGMRNLHQPEKAQLRLQKAYDLALAALHDLRRSVWNLSAPAIDGRVLSDVLAELVDT
FHQRTNIQSQYSHDGQELTLPSDVAIQVLRVVNEALSNVEKHAQAKHVAIRSTVAAGQLQITVSDDGQGFELAAVQQTAS
GGFGLTSMRERTQLIQGSLSIQSQPSAGTLLTLCLPL
>Mature_517_residues
MMHPEPITIDQQTPQDRVHNQSLLWSGVIAALVACGVPPIIGLSDGSLRGVNLVIYLGAAIGYIGLKSVFWFETPLCNRF
RRNPQLLISVVFGLAALMQLLSRDFTTQPIAFMVPMVFIAGTYPLPKTLIIAGLIAILMSGSFIAAGLPLTSAGLSALSS
QIVLLLFVTLFGYVTNQSVLTRQKVEQLAQELAQERDYLQQLSAITAALSSEVQLARVLAQVAEAGRSLANAQAVTVALL
EDPEWRIVASVGSPDTNLPSLEIMLHAKGETIGRLNYWSIQPTNAALRQALQPFADAAAMAIYNAQLYEQARFSATLAER
NRLARDFHDTLAQQLTGLRLQIEAGMRNLHQPEKAQLRLQKAYDLALAALHDLRRSVWNLSAPAIDGRVLSDVLAELVDT
FHQRTNIQSQYSHDGQELTLPSDVAIQVLRVVNEALSNVEKHAQAKHVAIRSTVAAGQLQITVSDDGQGFELAAVQQTAS
GGFGLTSMRERTQLIQGSLSIQSQPSAGTLLTLCLPL

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=338, Percent_Identity=26.0355029585799, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787474, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56061; Mature: 56061

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHPEPITIDQQTPQDRVHNQSLLWSGVIAALVACGVPPIIGLSDGSLRGVNLVIYLGAA
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEHEEEHHHH
IGYIGLKSVFWFETPLCNRFRRNPQLLISVVFGLAALMQLLSRDFTTQPIAFMVPMVFIA
HHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GTYPLPKTLIIAGLIAILMSGSFIAAGLPLTSAGLSALSSQIVLLLFVTLFGYVTNQSVL
CCCCCHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
TRQKVEQLAQELAQERDYLQQLSAITAALSSEVQLARVLAQVAEAGRSLANAQAVTVALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
EDPEWRIVASVGSPDTNLPSLEIMLHAKGETIGRLNYWSIQPTNAALRQALQPFADAAAM
ECCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
AIYNAQLYEQARFSATLAERNRLARDFHDTLAQQLTGLRLQIEAGMRNLHQPEKAQLRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCHHHHHHHH
KAYDLALAALHDLRRSVWNLSAPAIDGRVLSDVLAELVDTFHQRTNIQSQYSHDGQELTL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEECC
PSDVAIQVLRVVNEALSNVEKHAQAKHVAIRSTVAAGQLQITVSDDGQGFELAAVQQTAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHCC
GGFGLTSMRERTQLIQGSLSIQSQPSAGTLLTLCLPL
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MMHPEPITIDQQTPQDRVHNQSLLWSGVIAALVACGVPPIIGLSDGSLRGVNLVIYLGAA
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEHEEEHHHH
IGYIGLKSVFWFETPLCNRFRRNPQLLISVVFGLAALMQLLSRDFTTQPIAFMVPMVFIA
HHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GTYPLPKTLIIAGLIAILMSGSFIAAGLPLTSAGLSALSSQIVLLLFVTLFGYVTNQSVL
CCCCCHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
TRQKVEQLAQELAQERDYLQQLSAITAALSSEVQLARVLAQVAEAGRSLANAQAVTVALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
EDPEWRIVASVGSPDTNLPSLEIMLHAKGETIGRLNYWSIQPTNAALRQALQPFADAAAM
ECCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
AIYNAQLYEQARFSATLAERNRLARDFHDTLAQQLTGLRLQIEAGMRNLHQPEKAQLRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCHHHHHHHH
KAYDLALAALHDLRRSVWNLSAPAIDGRVLSDVLAELVDTFHQRTNIQSQYSHDGQELTL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEECC
PSDVAIQVLRVVNEALSNVEKHAQAKHVAIRSTVAAGQLQITVSDDGQGFELAAVQQTAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHCC
GGFGLTSMRERTQLIQGSLSIQSQPSAGTLLTLCLPL
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]