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The map label for this gene is kptA

Identifier: 159901400

GI number: 159901400

Start: 6225384

End: 6225932

Strand: Direct

Name: kptA

Synonym: Haur_4889

Alternate gene names: 159901400

Gene position: 6225384-6225932 (Clockwise)

Preceding gene: 159901394

Following gene: 159901401

Centisome position: 98.09

GC content: 51.73

Gene sequence:

>549_bases
ATGGATGAACGTCGATTAATTCGGGTTAGCAAATATCTGAGCAAACATCTACGCCATCAACCAGAGCGCTTGGGATTAAC
GCTTGAACCAGGTGGGTGGGTTGGGGTTGAGCAACTTTTAGCGGCCTGTGCGGCCAATAATGTTGCGATTAGCCTAGCCG
AGTTGCACGAAGTTGTTGAACAGAACAATAAACAACGCTTTGGCTTCGACCCAACTGGCCAAAAAATTCGTGCCCATCAA
GGCCATAGCGTGACGGTCGATTTAGGCCTCGTGGCCCAGCAACCGCCAATAATCCTGTATCACGGAACCGCCAAGCACAA
TCTAGCGATAATTCTGCGTGATGGGCTGCGGCCTATGCAACGCCAGCATGTCCACCTCTCGCGTGATCGGGCGACAGCGC
TGCAAGTCGGCGCACGTCACGGTCAAGCAGTGATTTTAATCGTCCAAGCTGACGAACTATTTCAAGCAGGGCAAGCCTTT
TTTTGCAGCGACAACGGCGTTTGGCTAACTACTGCAATTGATCCTGCCTATCTGGCGCTTGAACGCTAA

Upstream 100 bases:

>100_bases
CCAGAGACTGATGTCAAATCACTTAAGTTATGGTCAAATAAAGCTAGCAACGGAATGCAAGCAGCGCTTAATCTCAAGGC
CCAAAGGAGCCAACCACGCC

Downstream 100 bases:

>100_bases
ATAGGTTGGGTCATTCGGAGTCGGCAGATCGGGCTATGCTATAATACGCCCATCGCGCTTTGGCCACCCATGATCCAAGA
ACATCCACGGATTTTCCGCG

Product: RNA 2'-phosphotransferase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MDERRLIRVSKYLSKHLRHQPERLGLTLEPGGWVGVEQLLAACAANNVAISLAELHEVVEQNNKQRFGFDPTGQKIRAHQ
GHSVTVDLGLVAQQPPIILYHGTAKHNLAIILRDGLRPMQRQHVHLSRDRATALQVGARHGQAVILIVQADELFQAGQAF
FCSDNGVWLTTAIDPAYLALER

Sequences:

>Translated_182_residues
MDERRLIRVSKYLSKHLRHQPERLGLTLEPGGWVGVEQLLAACAANNVAISLAELHEVVEQNNKQRFGFDPTGQKIRAHQ
GHSVTVDLGLVAQQPPIILYHGTAKHNLAIILRDGLRPMQRQHVHLSRDRATALQVGARHGQAVILIVQADELFQAGQAF
FCSDNGVWLTTAIDPAYLALER
>Mature_182_residues
MDERRLIRVSKYLSKHLRHQPERLGLTLEPGGWVGVEQLLAACAANNVAISLAELHEVVEQNNKQRFGFDPTGQKIRAHQ
GHSVTVDLGLVAQQPPIILYHGTAKHNLAIILRDGLRPMQRQHVHLSRDRATALQVGARHGQAVILIVQADELFQAGQAF
FCSDNGVWLTTAIDPAYLALER

Specific function: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP- ribosy

COG id: COG1859

COG function: function code J; RNA:NAD 2'-phosphotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kptA/TPT1 family

Homologues:

Organism=Homo sapiens, GI238550149, Length=190, Percent_Identity=32.1052631578947, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI238550169, Length=189, Percent_Identity=34.9206349206349, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI238550157, Length=188, Percent_Identity=33.5106382978723, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI238550153, Length=188, Percent_Identity=33.5106382978723, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI87082424, Length=178, Percent_Identity=41.5730337078652, Blast_Score=141, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324470, Length=186, Percent_Identity=31.7204301075269, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KPTA_HERA2 (A9B356)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001547647.1
- ProteinModelPortal:   A9B356
- SMR:   A9B356
- GeneID:   5736724
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_4889
- HOGENOM:   HBG332834
- OMA:   CEIAVFI
- ProtClustDB:   PRK00819
- BioCyc:   HAUR316274:HAUR_4889-MONOMER
- HAMAP:   MF_00299
- InterPro:   IPR022928
- InterPro:   IPR002745

Pfam domain/function: PF01885 PTS_2-RNA

EC number: 2.7.-.- [C]

Molecular weight: Translated: 20226; Mature: 20226

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERRLIRVSKYLSKHLRHQPERLGLTLEPGGWVGVEQLLAACAANNVAISLAELHEVVE
CCCHHHHHHHHHHHHHHCCCHHHCCEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHH
QNNKQRFGFDPTGQKIRAHQGHSVTVDLGLVAQQPPIILYHGTAKHNLAIILRDGLRPMQ
CCCCEECCCCCCCCCEEECCCCEEEEEEEEEECCCCEEEEECCCCCCEEEEEECCCCHHH
RQHVHLSRDRATALQVGARHGQAVILIVQADELFQAGQAFFCSDNGVWLTTAIDPAYLAL
HHCEECCCCHHHHHHHCCCCCCEEEEEEECHHHHHCCCEEEECCCCEEEEEECCCEEEEE
ER
CC
>Mature Secondary Structure
MDERRLIRVSKYLSKHLRHQPERLGLTLEPGGWVGVEQLLAACAANNVAISLAELHEVVE
CCCHHHHHHHHHHHHHHCCCHHHCCEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHH
QNNKQRFGFDPTGQKIRAHQGHSVTVDLGLVAQQPPIILYHGTAKHNLAIILRDGLRPMQ
CCCCEECCCCCCCCCEEECCCCEEEEEEEEEECCCCEEEEECCCCCCEEEEEECCCCHHH
RQHVHLSRDRATALQVGARHGQAVILIVQADELFQAGQAFFCSDNGVWLTTAIDPAYLAL
HHCEECCCCHHHHHHHCCCCCCEEEEEEECHHHHHCCCEEEECCCCEEEEEECCCEEEEE
ER
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA