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The map label for this gene is mtaD1 [H]

Identifier: 159901377

GI number: 159901377

Start: 6199364

End: 6201346

Strand: Reverse

Name: mtaD1 [H]

Synonym: Haur_4866

Alternate gene names: 159901377

Gene position: 6201346-6199364 (Counterclockwise)

Preceding gene: 159901378

Following gene: 159901374

Centisome position: 97.71

GC content: 52.75

Gene sequence:

>1983_bases
ATGGCTTTACAACAAATTGATACCCTGCTGCTTAATGGCATCGTCGTCACAATGGACGCAGCAGGCACGATCATTCGTGA
TGGTGGGGTGGCAATTCAGGCTGGTGCAATCGTCGAGGTCGGGCCAAGCAGCCAGTTGCGCGAACGCTATACCGCCAGCC
AAACGATCGACTGTAACAATCATGCCATTGTGCCTGGCTTAATCAACGGCCATGCTCACGTTCCAATGAGTTTGTTGCGC
GGCATCGTCGCCGATCAGCAGCTGGATGTGTGGCTCTATGGCTATATGTTTCCGGTCGAGAGTCGCTTTGTTAACCCCGA
ATTTGTCTACCATGGCACGCGCCTCTCGTGTGCCGAAATGATCAAGGGCGGCATTACCAGCTTCGTCGATATGTATTATT
TCGAGGAAGAAGTAGCCCGCGCCGCTGATCAAGCTGGGATGCGGGCGATCTGTGGCCAAACCGTGATGAAATGGCCAACC
CCCGATGCTGCCTCTTACGACGAAGGTCTAGAGCGCACTCGCCGCTTTTTCGAGCAATGGAAAGATCATGGTCGGGTGAT
TCCGGCGATTGCGCCGCACGCACCCTACACCTGTAACAGCACCATCTATCGCGCTGCCGCCGAATTGGCTCGCGAATTCG
ATGTGCCGCTAGTAACTCACCTCAGCGAAACCGCCCGCGAAGTCGAAGAAGCCCGCCAGTTGGTCGATAAATCGCCAATC
GCCTATGTCGCTGATTTGGATGCCTTCACCGATAAAGGGATTGCGGCCCACTGTGTACACATCGACAAACGTGATATGCA
ATTACTCAAAAAGCATAACGCAGGAGCCGTGCCCTGCCCAACCAGCAACCTCAAACTGGCGAGCGGCGTGGCCAAATATG
GCGAAATGCTGCAAGCTGGTGTGAATGTAGGGCTTGGCACTGATGGCCCCGCCTCCAACGACGACCAGGATTTGTGGTTG
GAAGTGCACTTAGCAGCCATCTTGCCCAAGGGTGTCACGGGCGATCCCACCGTAGTCAACGCCAAGCAGGCTTTTGCTAT
GGCTACGAGCATGGGTGCTAAAGCTGTGCACCTTGATCATTTGGTTGGCAGCGTCGAAGCGGGCAAACGCGCCGATATCA
CAATTGTTGATTTGGGTGGATTGCACGTCGTGCCAGCTCCAGCCTATAACTACAGCAACGATTCAATCTACAATCACTTG
GTCTACTCAGCCCGTTCGGGCGATGTACGCCATGTGTTGATCGATGGTGCTTGGGTACTGCAAGATCGCCAATTGTTGAC
GCTTGATGAAACCGAAGTTCGGAGCAATGCCCTGCGGATCGCCGAAACGATCAATCAATTCCTCAGCCAACGTGAAGTCA
ATTTGTTGGATAAAATTCTGGCGATCGGTGGAGTTAAACAAGCCGAAATCTTCGAAGTTCAAGTCAAGGCGCGTTTGGAA
GATGCTAGCAGCGTTGAAGCTTTCCTCGAATCAGAGGCGGTCGAAATTACCAAGGCGAGCGAACGCAAGCAATACGACAC
CTACTTCAGCTTCGATGATCCTAGTCGTGGGCGGATTCGTTACCGTGAAGATCATCGGGTTGATGGCTCGCGGCTTGAGC
CAAAATACAATTTGACTTTGACCATGCCCAATGAGCGTGAAGATTTGCCCTCGGCAGTCTTGCTTTCACGGGCACGCTAC
ACCGCCCCAGCCGATCGTTCGTTACGCTTCTATCGTGAATATTTCTCGCCCGATCATGTGATCGAAGTTGAGAAATATCG
CCGCCGCTGGCGGATTATGTATGGCGAGGTTGATTTTGCGATCAATATCGACATGATCACCAGTGGCCCCGCCAAAGGCA
CCTATTTAGAAATCAAGAGCCGTACTTGGTCGGCCCGTGATGCTGAAGGCAAAACCCAAATTATCAGCGAATTGTTGCAG
ATGGCCGGAGTCAAGCCCGACCACATTATCAAGCAAGAATACGTTGAACTAGCCCAAGCTTAA

Upstream 100 bases:

>100_bases
GGTACAATCACCTGAATACCTCCCGCCAGACGGGACCCAAATATGCCATCTAAGGCACAAGCGATGATGCTTGTGCTTTT
GTGCAACATAAGGAGGCCAA

Downstream 100 bases:

>100_bases
ACTCAAAATCCCGCAGCCATGGAGTTCATGGCTGCGGGATTGGTTCGGTTGGCAAGGCAATGATTACTTGATCGTGATGC
TCGAGGCTGATCCTGAGAGA

Product: amidohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase 1 [H]

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MALQQIDTLLLNGIVVTMDAAGTIIRDGGVAIQAGAIVEVGPSSQLRERYTASQTIDCNNHAIVPGLINGHAHVPMSLLR
GIVADQQLDVWLYGYMFPVESRFVNPEFVYHGTRLSCAEMIKGGITSFVDMYYFEEEVARAADQAGMRAICGQTVMKWPT
PDAASYDEGLERTRRFFEQWKDHGRVIPAIAPHAPYTCNSTIYRAAAELAREFDVPLVTHLSETAREVEEARQLVDKSPI
AYVADLDAFTDKGIAAHCVHIDKRDMQLLKKHNAGAVPCPTSNLKLASGVAKYGEMLQAGVNVGLGTDGPASNDDQDLWL
EVHLAAILPKGVTGDPTVVNAKQAFAMATSMGAKAVHLDHLVGSVEAGKRADITIVDLGGLHVVPAPAYNYSNDSIYNHL
VYSARSGDVRHVLIDGAWVLQDRQLLTLDETEVRSNALRIAETINQFLSQREVNLLDKILAIGGVKQAEIFEVQVKARLE
DASSVEAFLESEAVEITKASERKQYDTYFSFDDPSRGRIRYREDHRVDGSRLEPKYNLTLTMPNEREDLPSAVLLSRARY
TAPADRSLRFYREYFSPDHVIEVEKYRRRWRIMYGEVDFAINIDMITSGPAKGTYLEIKSRTWSARDAEGKTQIISELLQ
MAGVKPDHIIKQEYVELAQA

Sequences:

>Translated_660_residues
MALQQIDTLLLNGIVVTMDAAGTIIRDGGVAIQAGAIVEVGPSSQLRERYTASQTIDCNNHAIVPGLINGHAHVPMSLLR
GIVADQQLDVWLYGYMFPVESRFVNPEFVYHGTRLSCAEMIKGGITSFVDMYYFEEEVARAADQAGMRAICGQTVMKWPT
PDAASYDEGLERTRRFFEQWKDHGRVIPAIAPHAPYTCNSTIYRAAAELAREFDVPLVTHLSETAREVEEARQLVDKSPI
AYVADLDAFTDKGIAAHCVHIDKRDMQLLKKHNAGAVPCPTSNLKLASGVAKYGEMLQAGVNVGLGTDGPASNDDQDLWL
EVHLAAILPKGVTGDPTVVNAKQAFAMATSMGAKAVHLDHLVGSVEAGKRADITIVDLGGLHVVPAPAYNYSNDSIYNHL
VYSARSGDVRHVLIDGAWVLQDRQLLTLDETEVRSNALRIAETINQFLSQREVNLLDKILAIGGVKQAEIFEVQVKARLE
DASSVEAFLESEAVEITKASERKQYDTYFSFDDPSRGRIRYREDHRVDGSRLEPKYNLTLTMPNEREDLPSAVLLSRARY
TAPADRSLRFYREYFSPDHVIEVEKYRRRWRIMYGEVDFAINIDMITSGPAKGTYLEIKSRTWSARDAEGKTQIISELLQ
MAGVKPDHIIKQEYVELAQA
>Mature_659_residues
ALQQIDTLLLNGIVVTMDAAGTIIRDGGVAIQAGAIVEVGPSSQLRERYTASQTIDCNNHAIVPGLINGHAHVPMSLLRG
IVADQQLDVWLYGYMFPVESRFVNPEFVYHGTRLSCAEMIKGGITSFVDMYYFEEEVARAADQAGMRAICGQTVMKWPTP
DAASYDEGLERTRRFFEQWKDHGRVIPAIAPHAPYTCNSTIYRAAAELAREFDVPLVTHLSETAREVEEARQLVDKSPIA
YVADLDAFTDKGIAAHCVHIDKRDMQLLKKHNAGAVPCPTSNLKLASGVAKYGEMLQAGVNVGLGTDGPASNDDQDLWLE
VHLAAILPKGVTGDPTVVNAKQAFAMATSMGAKAVHLDHLVGSVEAGKRADITIVDLGGLHVVPAPAYNYSNDSIYNHLV
YSARSGDVRHVLIDGAWVLQDRQLLTLDETEVRSNALRIAETINQFLSQREVNLLDKILAIGGVKQAEIFEVQVKARLED
ASSVEAFLESEAVEITKASERKQYDTYFSFDDPSRGRIRYREDHRVDGSRLEPKYNLTLTMPNEREDLPSAVLLSRARYT
APADRSLRFYREYFSPDHVIEVEKYRRRWRIMYGEVDFAINIDMITSGPAKGTYLEIKSRTWSARDAEGKTQIISELLQM
AGVKPDHIIKQEYVELAQA

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=330, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI1789249, Length=417, Percent_Identity=26.6187050359712, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87082177, Length=439, Percent_Identity=25.2847380410023, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17540282, Length=399, Percent_Identity=23.8095238095238, Blast_Score=86, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6319963, Length=345, Percent_Identity=23.4782608695652, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24643849, Length=390, Percent_Identity=28.7179487179487, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 73313; Mature: 73182

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQQIDTLLLNGIVVTMDAAGTIIRDGGVAIQAGAIVEVGPSSQLRERYTASQTIDCNN
CCHHHHHHHHHCCEEEEEECCCEEEECCCEEEEECEEEEECCCHHHHHHHCCCCEECCCC
HAIVPGLINGHAHVPMSLLRGIVADQQLDVWLYGYMFPVESRFVNPEFVYHGTRLSCAEM
CEEECEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCCCCEEEECCCCCHHHH
IKGGITSFVDMYYFEEEVARAADQAGMRAICGQTVMKWPTPDAASYDEGLERTRRFFEQW
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHH
KDHGRVIPAIAPHAPYTCNSTIYRAAAELAREFDVPLVTHLSETAREVEEARQLVDKSPI
HHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AYVADLDAFTDKGIAAHCVHIDKRDMQLLKKHNAGAVPCPTSNLKLASGVAKYGEMLQAG
EEEEECHHHCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
VNVGLGTDGPASNDDQDLWLEVHLAAILPKGVTGDPTVVNAKQAFAMATSMGAKAVHLDH
CCCCCCCCCCCCCCCCCEEEEEEEEHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEHHH
LVGSVEAGKRADITIVDLGGLHVVPAPAYNYSNDSIYNHLVYSARSGDVRHVLIDGAWVL
HHHHCCCCCCCCEEEEEECCEEEECCCCCCCCCCHHHHHHEEECCCCCEEEEEEECEEEE
QDRQLLTLDETEVRSNALRIAETINQFLSQREVNLLDKILAIGGVKQAEIFEVQVKARLE
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHC
DASSVEAFLESEAVEITKASERKQYDTYFSFDDPSRGRIRYREDHRVDGSRLEPKYNLTL
CHHHHHHHHHHHHHEEHHHHCCCCCCCEECCCCCCCCCEEECCCCCCCCCCCCCEEEEEE
TMPNEREDLPSAVLLSRARYTAPADRSLRFYREYFSPDHVIEVEKYRRRWRIMYGEVDFA
ECCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHEEEEEEEEEEE
INIDMITSGPAKGTYLEIKSRTWSARDAEGKTQIISELLQMAGVKPDHIIKQEYVELAQA
EEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALQQIDTLLLNGIVVTMDAAGTIIRDGGVAIQAGAIVEVGPSSQLRERYTASQTIDCNN
CHHHHHHHHHCCEEEEEECCCEEEECCCEEEEECEEEEECCCHHHHHHHCCCCEECCCC
HAIVPGLINGHAHVPMSLLRGIVADQQLDVWLYGYMFPVESRFVNPEFVYHGTRLSCAEM
CEEECEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCCCCEEEECCCCCHHHH
IKGGITSFVDMYYFEEEVARAADQAGMRAICGQTVMKWPTPDAASYDEGLERTRRFFEQW
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHH
KDHGRVIPAIAPHAPYTCNSTIYRAAAELAREFDVPLVTHLSETAREVEEARQLVDKSPI
HHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AYVADLDAFTDKGIAAHCVHIDKRDMQLLKKHNAGAVPCPTSNLKLASGVAKYGEMLQAG
EEEEECHHHCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
VNVGLGTDGPASNDDQDLWLEVHLAAILPKGVTGDPTVVNAKQAFAMATSMGAKAVHLDH
CCCCCCCCCCCCCCCCCEEEEEEEEHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEHHH
LVGSVEAGKRADITIVDLGGLHVVPAPAYNYSNDSIYNHLVYSARSGDVRHVLIDGAWVL
HHHHCCCCCCCCEEEEEECCEEEECCCCCCCCCCHHHHHHEEECCCCCEEEEEEECEEEE
QDRQLLTLDETEVRSNALRIAETINQFLSQREVNLLDKILAIGGVKQAEIFEVQVKARLE
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHC
DASSVEAFLESEAVEITKASERKQYDTYFSFDDPSRGRIRYREDHRVDGSRLEPKYNLTL
CHHHHHHHHHHHHHEEHHHHCCCCCCCEECCCCCCCCCEEECCCCCCCCCCCCCEEEEEE
TMPNEREDLPSAVLLSRARYTAPADRSLRFYREYFSPDHVIEVEKYRRRWRIMYGEVDFA
ECCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHEEEEEEEEEEE
INIDMITSGPAKGTYLEIKSRTWSARDAEGKTQIISELLQMAGVKPDHIIKQEYVELAQA
EEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA