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The map label for this gene is rsbRA [H]

Identifier: 159901283

GI number: 159901283

Start: 6086405

End: 6087100

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_4771

Alternate gene names: 159901283

Gene position: 6086405-6087100 (Clockwise)

Preceding gene: 159901282

Following gene: 159901284

Centisome position: 95.9

GC content: 49.86

Gene sequence:

>696_bases
ATGGATCAACCAGAGCGCCCAGAGCAACCAACGCCTCCAGCATCGACCAACCAATCACGACTTTCACGTGAAGATCGGGC
GCTAATTCGCACGATTGGCAGTACGTTGCGCAAAGTTATTCAAGGCGAGGCTGCTGAACATCTTGTGCTTGATCGTCGCG
ATGAACTCGGAATTTTGGCCAATATGGTCAATCGAGTCAGCAAAGAGCTTGCGCTCTCCCGCGAACAGGATCAAAAACAC
CTGGCGGAGCTTGAAGCTCGGCTAGCCGAGTTGAAGGCAGCCCGCGAAACCGAAGAACGACTGCTGTATACGATCGATGA
AATTTCAACCCCGATTCTTAATATTTTTACCAACGTGGTGTTGATGCCATTGATCGGTGCAATCGATAGCAATCGCGCTC
AACGCATGATTGCGCTCTTGTTGGAGCATGTCGTGCGCACGCGAGCGAGTGTCGTGATTTTGGATATTACGGCGGTTTCA
TTAATTGATACCCAAGTGGCCAATGTGCTGATTCGGGCAGCGCAATCGTGTAATTTGCTTGGTGCTGGCGTTATTTTATG
TGGCATGACCCCTGATGTTGCCCAAGTTGTCGTAAGCCTTGGAATTGATCTTTCGATTTTTCAAACCACCAGCGATTTAC
AAGAAGCGCTCTCGACAGCCCTGCGTACCCTCAAGTACCGTATTCAGCCTATGTAA

Upstream 100 bases:

>100_bases
TGGAGTGCTTCGATGCCCGCGATGTTCAAATGAACCATTCTAAGTGTATCCGCAATGGCGATGCCTTCTGCGAGTTACAT
GTTTCTTGGAAATAAATCCT

Downstream 100 bases:

>100_bases
AGCATAGACTATTGGCCTATTGAGCCTAGTACTGACATCTAATACAGTATATGCAGTCAGGACAGATGCAAAAGCTGACT
CGCAGATTCACACTTGACAC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MDQPERPEQPTPPASTNQSRLSREDRALIRTIGSTLRKVIQGEAAEHLVLDRRDELGILANMVNRVSKELALSREQDQKH
LAELEARLAELKAARETEERLLYTIDEISTPILNIFTNVVLMPLIGAIDSNRAQRMIALLLEHVVRTRASVVILDITAVS
LIDTQVANVLIRAAQSCNLLGAGVILCGMTPDVAQVVVSLGIDLSIFQTTSDLQEALSTALRTLKYRIQPM

Sequences:

>Translated_231_residues
MDQPERPEQPTPPASTNQSRLSREDRALIRTIGSTLRKVIQGEAAEHLVLDRRDELGILANMVNRVSKELALSREQDQKH
LAELEARLAELKAARETEERLLYTIDEISTPILNIFTNVVLMPLIGAIDSNRAQRMIALLLEHVVRTRASVVILDITAVS
LIDTQVANVLIRAAQSCNLLGAGVILCGMTPDVAQVVVSLGIDLSIFQTTSDLQEALSTALRTLKYRIQPM
>Mature_231_residues
MDQPERPEQPTPPASTNQSRLSREDRALIRTIGSTLRKVIQGEAAEHLVLDRRDELGILANMVNRVSKELALSREQDQKH
LAELEARLAELKAARETEERLLYTIDEISTPILNIFTNVVLMPLIGAIDSNRAQRMIALLLEHVVRTRASVVILDITAVS
LIDTQVANVLIRAAQSCNLLGAGVILCGMTPDVAQVVVSLGIDLSIFQTTSDLQEALSTALRTLKYRIQPM

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 25521; Mature: 25521

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQPERPEQPTPPASTNQSRLSREDRALIRTIGSTLRKVIQGEAAEHLVLDRRDELGILA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
NMVNRVSKELALSREQDQKHLAELEARLAELKAARETEERLLYTIDEISTPILNIFTNVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMPLIGAIDSNRAQRMIALLLEHVVRTRASVVILDITAVSLIDTQVANVLIRAAQSCNLL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHH
GAGVILCGMTPDVAQVVVSLGIDLSIFQTTSDLQEALSTALRTLKYRIQPM
HHHHHEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDQPERPEQPTPPASTNQSRLSREDRALIRTIGSTLRKVIQGEAAEHLVLDRRDELGILA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
NMVNRVSKELALSREQDQKHLAELEARLAELKAARETEERLLYTIDEISTPILNIFTNVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMPLIGAIDSNRAQRMIALLLEHVVRTRASVVILDITAVSLIDTQVANVLIRAAQSCNLL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHH
GAGVILCGMTPDVAQVVVSLGIDLSIFQTTSDLQEALSTALRTLKYRIQPM
HHHHHEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]