Click here to switch to the map view.

The map label for this gene is pgi [H]

Identifier: 159901187

GI number: 159901187

Start: 5971799

End: 5973193

Strand: Direct

Name: pgi [H]

Synonym: Haur_4675

Alternate gene names: 159901187

Gene position: 5971799-5973193 (Clockwise)

Preceding gene: 159901186

Following gene: 159901189

Centisome position: 94.09

GC content: 51.61

Gene sequence:

>1395_bases
ATGAGTACTCAAGCTATTCGCTTTGATTACAACAATGTGATGGCCGATGTGATTGGTGAACATGGATTGACTGAGGCTGA
AATTGAGGCAGCATTGCCCCATGCCGCCGCCGCGATTGAAGCTGTCTATGCTCAACGCGCCGATCTCGGCTGGATGGATT
TGCCCTATCAAGATACCAGTGAAATTATTGCTCAAGCCCAAGCTGTGCGTGCTCGCGCCGACACGTTGGTGGTTTTAGGC
ATTGGTGGCTCAGCGCTTGGCCCAATCGCAACCCAAACGGCTCTCCAGCACCCATTTTATAATAATTTGCCGCGTGAATT
GCGCCGTGGCCCCACGTTGTTTGTACCCGATAATGTTGACCCTGAATTAAACGCTGGCTTGCTCGATGTGCTTGATCTTG
AGCGCACCGTGTTCAATGTGATCACCAAATCGGGCACGACTGCCGAAACCATGGCATCCTTCATTTACTTCCGCGAAGCC
TTGGCCAAACGCCTTGGTAAGGATAAATTAGTTGATCACTTGGTGTTGACGACAGACCCTAAGAAGGGAGCCTTGCGCCA
AATTGCTGATCGCGAGGGCTACCCAACCTTGCCCTTACCAGCCAGCGTTGGTGGCCGCTTCTCGGAACTTTGCGCAGTTG
GCTTGTTCCCAGCGGCTGTTACTGGCATCGATATTGATGAATTGTTGGCGGGGGCAGCCTATGCTGACAAACGTAGCCAA
GAGCGCGACCCGCGCAAAAATCCCGCCGCAATGTGTGCATTAATCCAATTCTTGCTCGATAAGAAGGGTAAGAATATGGT
TGTGATGATGCCCTATGCTCAGCGTTTACGCGATGTGGCTGATTGGTTCCGCCAATTGTGGGCTGAAAGTTTGGGCAAGC
GGGTTGATCGGGCTGGCAATGTGGTCAATGTTGGCCCTACACCAATCAAATCGTTGGGCGCGACCGACCAACATTCGCAA
GTGCAACTCTATGCTGAAGGCCCATTCGATAAATTGATGCACTTCTTGTTTGTTGAGCAGTTCCAAGTGGAAGCACCGTT
GAGCAATGCCTACCCCGATATCAACGAGCTTTCGTATCTTGATGGCAAGAGCTTTAGCCAATTGCTCAAAGCCGAGGGCG
AAGCAACCCAGTTGGCGATTGCCGAAGCTGGTCGCCCCAGCATTGCCCATTATTTCCCAGCAGTCAATGCCTTTACGCTT
GGGCAATTCTACTACATGCTCGAAATGCAAACCGCCTTTGCTGGCGAGTTGTACAACATCAATGCTTTTGATCAGCCTGG
AGTTGAGGCTGGTAAAATCGCTACCTACGCCTTGATGGGTCGCGAAGGCTACGATGCTCGCCGCCACGAAATTGAACAAG
CTCGTGGCCGCAGCCGTAGCGAATTTATCATCTAA

Upstream 100 bases:

>100_bases
TGGTACGATGGGCAAAGTTGGCCGCTGGGCAACGAAGCCTTGCAACTGCACCGCCGCAGCCTACGACAAAGACCCAATTT
CGCAAACAATAAGGAGTGTC

Downstream 100 bases:

>100_bases
ACCCAATTGATCAGACCTGCCATGCTCAAACCATGGCAGGTTTTTTACTCCTTACGCCCGATGCTTGAATCCTACAACTT
TGAAAGAATCGAGGCCAAAC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSTQAIRFDYNNVMADVIGEHGLTEAEIEAALPHAAAAIEAVYAQRADLGWMDLPYQDTSEIIAQAQAVRARADTLVVLG
IGGSALGPIATQTALQHPFYNNLPRELRRGPTLFVPDNVDPELNAGLLDVLDLERTVFNVITKSGTTAETMASFIYFREA
LAKRLGKDKLVDHLVLTTDPKKGALRQIADREGYPTLPLPASVGGRFSELCAVGLFPAAVTGIDIDELLAGAAYADKRSQ
ERDPRKNPAAMCALIQFLLDKKGKNMVVMMPYAQRLRDVADWFRQLWAESLGKRVDRAGNVVNVGPTPIKSLGATDQHSQ
VQLYAEGPFDKLMHFLFVEQFQVEAPLSNAYPDINELSYLDGKSFSQLLKAEGEATQLAIAEAGRPSIAHYFPAVNAFTL
GQFYYMLEMQTAFAGELYNINAFDQPGVEAGKIATYALMGREGYDARRHEIEQARGRSRSEFII

Sequences:

>Translated_464_residues
MSTQAIRFDYNNVMADVIGEHGLTEAEIEAALPHAAAAIEAVYAQRADLGWMDLPYQDTSEIIAQAQAVRARADTLVVLG
IGGSALGPIATQTALQHPFYNNLPRELRRGPTLFVPDNVDPELNAGLLDVLDLERTVFNVITKSGTTAETMASFIYFREA
LAKRLGKDKLVDHLVLTTDPKKGALRQIADREGYPTLPLPASVGGRFSELCAVGLFPAAVTGIDIDELLAGAAYADKRSQ
ERDPRKNPAAMCALIQFLLDKKGKNMVVMMPYAQRLRDVADWFRQLWAESLGKRVDRAGNVVNVGPTPIKSLGATDQHSQ
VQLYAEGPFDKLMHFLFVEQFQVEAPLSNAYPDINELSYLDGKSFSQLLKAEGEATQLAIAEAGRPSIAHYFPAVNAFTL
GQFYYMLEMQTAFAGELYNINAFDQPGVEAGKIATYALMGREGYDARRHEIEQARGRSRSEFII
>Mature_463_residues
STQAIRFDYNNVMADVIGEHGLTEAEIEAALPHAAAAIEAVYAQRADLGWMDLPYQDTSEIIAQAQAVRARADTLVVLGI
GGSALGPIATQTALQHPFYNNLPRELRRGPTLFVPDNVDPELNAGLLDVLDLERTVFNVITKSGTTAETMASFIYFREAL
AKRLGKDKLVDHLVLTTDPKKGALRQIADREGYPTLPLPASVGGRFSELCAVGLFPAAVTGIDIDELLAGAAYADKRSQE
RDPRKNPAAMCALIQFLLDKKGKNMVVMMPYAQRLRDVADWFRQLWAESLGKRVDRAGNVVNVGPTPIKSLGATDQHSQV
QLYAEGPFDKLMHFLFVEQFQVEAPLSNAYPDINELSYLDGKSFSQLLKAEGEATQLAIAEAGRPSIAHYFPAVNAFTLG
QFYYMLEMQTAFAGELYNINAFDQPGVEAGKIATYALMGREGYDARRHEIEQARGRSRSEFII

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=384, Percent_Identity=28.6458333333333, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI296080693, Length=350, Percent_Identity=28.2857142857143, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI1790457, Length=396, Percent_Identity=30.5555555555556, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71996703, Length=386, Percent_Identity=28.2383419689119, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71996708, Length=386, Percent_Identity=28.2383419689119, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319673, Length=388, Percent_Identity=28.6082474226804, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24651916, Length=381, Percent_Identity=27.0341207349081, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24651914, Length=381, Percent_Identity=27.0341207349081, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17737445, Length=381, Percent_Identity=27.0341207349081, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 51020; Mature: 50888

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQAIRFDYNNVMADVIGEHGLTEAEIEAALPHAAAAIEAVYAQRADLGWMDLPYQDTS
CCCCEEEECHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EIIAQAQAVRARADTLVVLGIGGSALGPIATQTALQHPFYNNLPRELRRGPTLFVPDNVD
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCEEEECCCCC
PELNAGLLDVLDLERTVFNVITKSGTTAETMASFIYFREALAKRLGKDKLVDHLVLTTDP
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCC
KKGALRQIADREGYPTLPLPASVGGRFSELCAVGLFPAAVTGIDIDELLAGAAYADKRSQ
CHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ERDPRKNPAAMCALIQFLLDKKGKNMVVMMPYAQRLRDVADWFRQLWAESLGKRVDRAGN
CCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVNVGPTPIKSLGATDQHSQVQLYAEGPFDKLMHFLFVEQFQVEAPLSNAYPDINELSYL
EEECCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
DGKSFSQLLKAEGEATQLAIAEAGRPSIAHYFPAVNAFTLGQFYYMLEMQTAFAGELYNI
CCHHHHHHHHCCCCHHEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEC
NAFDQPGVEAGKIATYALMGREGYDARRHEIEQARGRSRSEFII
CCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
STQAIRFDYNNVMADVIGEHGLTEAEIEAALPHAAAAIEAVYAQRADLGWMDLPYQDTS
CCCEEEECHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EIIAQAQAVRARADTLVVLGIGGSALGPIATQTALQHPFYNNLPRELRRGPTLFVPDNVD
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCEEEECCCCC
PELNAGLLDVLDLERTVFNVITKSGTTAETMASFIYFREALAKRLGKDKLVDHLVLTTDP
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCC
KKGALRQIADREGYPTLPLPASVGGRFSELCAVGLFPAAVTGIDIDELLAGAAYADKRSQ
CHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ERDPRKNPAAMCALIQFLLDKKGKNMVVMMPYAQRLRDVADWFRQLWAESLGKRVDRAGN
CCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVNVGPTPIKSLGATDQHSQVQLYAEGPFDKLMHFLFVEQFQVEAPLSNAYPDINELSYL
EEECCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
DGKSFSQLLKAEGEATQLAIAEAGRPSIAHYFPAVNAFTLGQFYYMLEMQTAFAGELYNI
CCHHHHHHHHCCCCHHEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEC
NAFDQPGVEAGKIATYALMGREGYDARRHEIEQARGRSRSEFII
CCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA