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The map label for this gene is hutH [H]

Identifier: 159901141

GI number: 159901141

Start: 5914984

End: 5916570

Strand: Direct

Name: hutH [H]

Synonym: Haur_4629

Alternate gene names: 159901141

Gene position: 5914984-5916570 (Clockwise)

Preceding gene: 159901140

Following gene: 159901144

Centisome position: 93.2

GC content: 53.25

Gene sequence:

>1587_bases
GTGGAATGTTTAGTGCTCAATGGCGAGCAGTTAACAGTTGATGGTTTGGTGGCTGCCGCTCGTAATCCGGCAATTAAGGT
CGAATTAGCGCCCGAAGCAATTGAACGAATGCACTATTCTCGCGCTGCCGTCGAGCGATTTGTGGCCGAAGGTCGCGTGG
TCTATGGCATTACCACGGGCTTTGGTCATTTTCAAAATCGTACAATCGATCGCGACCATGTGCGCGAGTTGCAACGCAAT
ATTATTATGAGCCACGCCACTGGCACAGGCACGCCGCTGCGCCGCGACCAAGTACGCGCCATGTTGATCGTGCGAGTCAA
TACCTTGGCTAAAGGCTTTTCAGGGATTCGCCCGCTGGTTGCACAAGCCTTGCTTGATCTGCTCAACGCCGATATTTTGC
CAATTATTCCTTGTCAAGGCTCGCTTGGAGCTAGCGGCGATTTGGCTCCCCTCGCCCATGCCTGTTTGATTTTGCTGGGC
TTGGGCGAGGCGGTTGCTCCAGGTCAATCGCCAGTCCATGGCCAACGCATGAGTGGAGCCGAAGTTTTAGCCCACTTGCA
GCAAGAACCTTTGGTTTTAGAGGCTAAAGAAGGCTTAGCATTAACTAATGGCACGGCATTATTGAGTGGCTTAGCCGCCT
TGGCAATCTACGATGCCGAGCAACTTTGCCGCAGTGCCGAGACTATCGCCGCCTTGTCGATGGAAGCTTTGGCGGCTTTG
CCAGCAGCCTTCGATCAGCGGTTGCATGCAATTCGTCCGCATCCACGTCAGCTTGATAGTGCGCGGAGCATTCGTCAATT
GTTGCAAGGCAGTAGCTTTGTTTACCCCAGCCAAGCCGCTGATCCGACTATTTATGGGCCGCATAAAGTCCAAGATGCCT
ACTCGTTGCGCTGTGTGCCTCAAGTCCATGGGGCAATTCGCGATGCAGCCTGTTATGGGCGTTGGGCTACCGAGATTGAA
CTCAACAGCGCTACCGATAACCCCTTGATTGTTCCTGTTGATCCTGCGCAACCCCATGGCGAATATGAGGCGATTTCGGG
CGGTAACTTTCATGGTGAGCCTCTCGCATTAGCCATGGATTTTCTGAAAGTGGCGTTGAGCGAATTGGGCAACATCAGCG
AGCGCCGCACTGCTCGCTTGGTTGATGCAGGTTTGAATGGCAATTTACTCGCCCCGTTTTTAACCGAGCAAGGCGGCCTG
CACTCAGGCATGATGTTGATTCAATATACGGCTGTGGCTTTGGCGAGCGAAAATAAAGTGCTGGTACACCCCGCTGCTGC
TGATACGATTCCTACCTCGGGTAATCAAGAAGATCATGTCAGTATGGGGCCGACTGCTGCCCGTCAGGCTGCCGAGATGC
TCGATAATGTGGTGGGTATTTTGGCCTGTGAAGCCTTATGCGCGGCCCAAGCGATCGATTTACGTTGGCGCAAACACGAG
CATTTACAGCTGGGCCAAGGAACTGCGCCCGCCCATCAAGTAATTCGCCAGGTTGTGCCATTTCTAGCTGAAGATACCGT
GATGTACCCGCATATCGAAGGCCTGAAACAGGTGATTCAGGCTGGTAAATTGGCCTTAGCCGAATGA

Upstream 100 bases:

>100_bases
TCGTCCTAGCTCAACCATAATTAAACCCATCGCAAGCCCACCATTTGCTGACGGCTGGTATACTAGCGCCGAAAGCGAAT
TAAGCTAGCGAGGTAGCATT

Downstream 100 bases:

>100_bases
TTTGATAGGTAAGTTTAACCACGAAGGACACGAAGAGCACGAAGTGAGTAGGCTCTAGACTTTTGGCTATCGAAATTATT
AAGCTATTACCTCATGTCTC

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MECLVLNGEQLTVDGLVAAARNPAIKVELAPEAIERMHYSRAAVERFVAEGRVVYGITTGFGHFQNRTIDRDHVRELQRN
IIMSHATGTGTPLRRDQVRAMLIVRVNTLAKGFSGIRPLVAQALLDLLNADILPIIPCQGSLGASGDLAPLAHACLILLG
LGEAVAPGQSPVHGQRMSGAEVLAHLQQEPLVLEAKEGLALTNGTALLSGLAALAIYDAEQLCRSAETIAALSMEALAAL
PAAFDQRLHAIRPHPRQLDSARSIRQLLQGSSFVYPSQAADPTIYGPHKVQDAYSLRCVPQVHGAIRDAACYGRWATEIE
LNSATDNPLIVPVDPAQPHGEYEAISGGNFHGEPLALAMDFLKVALSELGNISERRTARLVDAGLNGNLLAPFLTEQGGL
HSGMMLIQYTAVALASENKVLVHPAAADTIPTSGNQEDHVSMGPTAARQAAEMLDNVVGILACEALCAAQAIDLRWRKHE
HLQLGQGTAPAHQVIRQVVPFLAEDTVMYPHIEGLKQVIQAGKLALAE

Sequences:

>Translated_528_residues
MECLVLNGEQLTVDGLVAAARNPAIKVELAPEAIERMHYSRAAVERFVAEGRVVYGITTGFGHFQNRTIDRDHVRELQRN
IIMSHATGTGTPLRRDQVRAMLIVRVNTLAKGFSGIRPLVAQALLDLLNADILPIIPCQGSLGASGDLAPLAHACLILLG
LGEAVAPGQSPVHGQRMSGAEVLAHLQQEPLVLEAKEGLALTNGTALLSGLAALAIYDAEQLCRSAETIAALSMEALAAL
PAAFDQRLHAIRPHPRQLDSARSIRQLLQGSSFVYPSQAADPTIYGPHKVQDAYSLRCVPQVHGAIRDAACYGRWATEIE
LNSATDNPLIVPVDPAQPHGEYEAISGGNFHGEPLALAMDFLKVALSELGNISERRTARLVDAGLNGNLLAPFLTEQGGL
HSGMMLIQYTAVALASENKVLVHPAAADTIPTSGNQEDHVSMGPTAARQAAEMLDNVVGILACEALCAAQAIDLRWRKHE
HLQLGQGTAPAHQVIRQVVPFLAEDTVMYPHIEGLKQVIQAGKLALAE
>Mature_528_residues
MECLVLNGEQLTVDGLVAAARNPAIKVELAPEAIERMHYSRAAVERFVAEGRVVYGITTGFGHFQNRTIDRDHVRELQRN
IIMSHATGTGTPLRRDQVRAMLIVRVNTLAKGFSGIRPLVAQALLDLLNADILPIIPCQGSLGASGDLAPLAHACLILLG
LGEAVAPGQSPVHGQRMSGAEVLAHLQQEPLVLEAKEGLALTNGTALLSGLAALAIYDAEQLCRSAETIAALSMEALAAL
PAAFDQRLHAIRPHPRQLDSARSIRQLLQGSSFVYPSQAADPTIYGPHKVQDAYSLRCVPQVHGAIRDAACYGRWATEIE
LNSATDNPLIVPVDPAQPHGEYEAISGGNFHGEPLALAMDFLKVALSELGNISERRTARLVDAGLNGNLLAPFLTEQGGL
HSGMMLIQYTAVALASENKVLVHPAAADTIPTSGNQEDHVSMGPTAARQAAEMLDNVVGILACEALCAAQAIDLRWRKHE
HLQLGQGTAPAHQVIRQVVPFLAEDTVMYPHIEGLKQVIQAGKLALAE

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=522, Percent_Identity=40.0383141762452, Blast_Score=360, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17567831, Length=524, Percent_Identity=43.3206106870229, Blast_Score=356, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 56397; Mature: 56397

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECLVLNGEQLTVDGLVAAARNPAIKVELAPEAIERMHYSRAAVERFVAEGRVVYGITTG
CEEEEECCCEEEHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
FGHFQNRTIDRDHVRELQRNIIMSHATGTGTPLRRDQVRAMLIVRVNTLAKGFSGIRPLV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEHEEEHHHHHHHHCCHHHHH
AQALLDLLNADILPIIPCQGSLGASGDLAPLAHACLILLGLGEAVAPGQSPVHGQRMSGA
HHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
EVLAHLQQEPLVLEAKEGLALTNGTALLSGLAALAIYDAEQLCRSAETIAALSMEALAAL
HHHHHHHCCCEEEEECCCEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
PAAFDQRLHAIRPHPRQLDSARSIRQLLQGSSFVYPSQAADPTIYGPHKVQDAYSLRCVP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCHHHEEEHH
QVHGAIRDAACYGRWATEIELNSATDNPLIVPVDPAQPHGEYEAISGGNFHGEPLALAMD
HHHHHHHHHHHHCCEEEEEEEECCCCCCEEEECCCCCCCCCEEECCCCCCCCCHHHHHHH
FLKVALSELGNISERRTARLVDAGLNGNLLAPFLTEQGGLHSGMMLIQYTAVALASENKV
HHHHHHHHHCCCHHHHHHHHHCCCCCCCEECHHHHCCCCCCCCHHHHHHHHHHEECCCEE
LVHPAAADTIPTSGNQEDHVSMGPTAARQAAEMLDNVVGILACEALCAAQAIDLRWRKHE
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HLQLGQGTAPAHQVIRQVVPFLAEDTVMYPHIEGLKQVIQAGKLALAE
CCCCCCCCCHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MECLVLNGEQLTVDGLVAAARNPAIKVELAPEAIERMHYSRAAVERFVAEGRVVYGITTG
CEEEEECCCEEEHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
FGHFQNRTIDRDHVRELQRNIIMSHATGTGTPLRRDQVRAMLIVRVNTLAKGFSGIRPLV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEHEEEHHHHHHHHCCHHHHH
AQALLDLLNADILPIIPCQGSLGASGDLAPLAHACLILLGLGEAVAPGQSPVHGQRMSGA
HHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
EVLAHLQQEPLVLEAKEGLALTNGTALLSGLAALAIYDAEQLCRSAETIAALSMEALAAL
HHHHHHHCCCEEEEECCCEEEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
PAAFDQRLHAIRPHPRQLDSARSIRQLLQGSSFVYPSQAADPTIYGPHKVQDAYSLRCVP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHCCHHHEEEHH
QVHGAIRDAACYGRWATEIELNSATDNPLIVPVDPAQPHGEYEAISGGNFHGEPLALAMD
HHHHHHHHHHHHCCEEEEEEEECCCCCCEEEECCCCCCCCCEEECCCCCCCCCHHHHHHH
FLKVALSELGNISERRTARLVDAGLNGNLLAPFLTEQGGLHSGMMLIQYTAVALASENKV
HHHHHHHHHCCCHHHHHHHHHCCCCCCCEECHHHHCCCCCCCCHHHHHHHHHHEECCCEE
LVHPAAADTIPTSGNQEDHVSMGPTAARQAAEMLDNVVGILACEALCAAQAIDLRWRKHE
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HLQLGQGTAPAHQVIRQVVPFLAEDTVMYPHIEGLKQVIQAGKLALAE
CCCCCCCCCHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA