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The map label for this gene is speA2 [H]

Identifier: 159901027

GI number: 159901027

Start: 5780692

End: 5782422

Strand: Reverse

Name: speA2 [H]

Synonym: Haur_4514

Alternate gene names: 159901027

Gene position: 5782422-5780692 (Counterclockwise)

Preceding gene: 159901028

Following gene: 159901026

Centisome position: 91.11

GC content: 53.09

Gene sequence:

>1731_bases
ATGTCGCCCGACACTTGGTTTTTTTATGCCCAAAAAATGGACAAAGCACTTTGGGAGTCTCCGTCAATAAACACACGCAC
GAACACCGCTAATTTTGATTGCACTTTGTTCTCTCAGCCCCATGTTGTGGCTGAGCACTATCGTCGTGGACATCACGGCT
TGGAGGGACATGTCCAGTTGATCGAGCAAACCTATGCTGGCTACCTGAATGATTCGTTTGGCTTTTCGGGTGCTGGGGCT
TTGACCGATTTTCTAACGCGCCGCAATGAGCGCTTGCTCTTAGGCGATACGGTCGATCTGGGTGCATTGGTTGAGCAATT
TGGTGCACCCCTTGAGGTTTCGTTCTGCCCGCAAATTACCACGCAGGTGCAGAATATGCTTGATTATGCGATGGCTGCAC
AGGCGGCATCAAGCTATACTGGCTCGTTCTTGTATGCTTATGCTACCAAGGCCAATTTTTCGGAGGAAGTGGTGCGCACA
GCCTTGAATGCTGGTGCTCATTACGAAACCTCAGCGGCAGCCGATGTGGTGATCGCTCACCATCTCTGGCGGCAAGGGGT
GCTTTCCGAAGATCGCTATATCTTCTGTAATGGCTCGAAAGAGCCGATGTATCTCGACGGGATCTTGGCTTTGCGCCAGG
CTGGCTACGAGCGAGTTGTGGCTGTGCTTGATGATCTCGATGAACTTGATTATATCTTGGCCCATTGTCGTGTACCGATG
TTGTTCGGTGTTCGTGAACGCCACGCCCCTGATGTCGTGGATCGTAACCATGCTGGAGCCGAGCGCTTTGGCTTAACTCC
CGCTGAAATGCAACTTGTCGCCCAGCGCTTGGCTGGCACGCAGCATCAATTGGTGGTGTATCACGCCATGGTTGGCTCGC
AAATTGAAGATGCAGCTGCATGGGAAGCTCGTTTGGCTCGTTCAGCCAATGCCTATGCCGCTTTGGCCAGCACTACTCCA
AGCCTAACGATGTTTAATTTTGGCGGGGGCATGCCCACCTCAGGCTACGATTTGGCCTTCCAATTTGATTATGTGGGCTT
TTTGACCAACTTGATGGCCAATACCCAAGCAATTTGTGCTGAGCATGGCGTGGCAGCACCCATGATCATCGCCGAATGTG
GCCGCTACACTGTTGCCAACCATAATCTCTATTTGATTGAAGTTGGCCGCGTGAAGGAAGCTGGCGCAATTGAGCCGTGG
TATTTGTTGAATGGCTCGTTGATGGTTTCAGCTCCCGATACCTTGATTGTTGACCAAGAATTCGTGGTTGTGCCCTTAGA
TGGTTGGGATACAGCGGTGCAAGCAGTGCGCTTGGGTGGCCGCCGCACCTGCGATTCCGACGATCTGTATCCACGTTCGC
ATCGCCCAGCCTTGATGTTGCCCGAATTCCAAGCTGGCATGGTCTTGGCGGTTTGTGGTGTTGGCGCATATCAGGCCATG
ATCGGCGGTAAGGGTGGTGCTCACCACTGCTTGAACCCCGAAATGCGCCGAATTATCATCGAGCAAGATGGCGATCAATT
GGTAATGCGCGAAATTGCCCCGCAAAACTTGATGGCACAAATGAGTGCCTTGGGTTATAGCATTGCCACGATTGAGCAGC
CAGTGCGCAAACCAATGCCAGTACGTACTGCCGTAGTCCGCGAGCAATTGCCAGTACGGCCATTGCGCACCGCCCGTCGT
CGCCAAGCTCCCTCAGCCTTGCGCACCAGCCGTTTCGCGGCAAGTGCCTAA

Upstream 100 bases:

>100_bases
GTGAGCTTTGCAATCATGCTAGCAGACTAGCAATGGTTCTCTGTCTATCTCCTCACCTGCCGCGATTGGGCAGGTTTTTT
ATGCCCAGTGCTTAGGCCAA

Downstream 100 bases:

>100_bases
CGCGGGTCAAAGAGCATAGAGCAACGAACATAGGAGCAAAGCGATTGGCTATCGGAAACACGATTAGGAGAATCCTAAAA
TATTCCGATAGCCAATCGCC

Product: Orn/DAP/Arg decarboxylase 2

Products: NA

Alternate protein names: ADC 2 [H]

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MSPDTWFFYAQKMDKALWESPSINTRTNTANFDCTLFSQPHVVAEHYRRGHHGLEGHVQLIEQTYAGYLNDSFGFSGAGA
LTDFLTRRNERLLLGDTVDLGALVEQFGAPLEVSFCPQITTQVQNMLDYAMAAQAASSYTGSFLYAYATKANFSEEVVRT
ALNAGAHYETSAAADVVIAHHLWRQGVLSEDRYIFCNGSKEPMYLDGILALRQAGYERVVAVLDDLDELDYILAHCRVPM
LFGVRERHAPDVVDRNHAGAERFGLTPAEMQLVAQRLAGTQHQLVVYHAMVGSQIEDAAAWEARLARSANAYAALASTTP
SLTMFNFGGGMPTSGYDLAFQFDYVGFLTNLMANTQAICAEHGVAAPMIIAECGRYTVANHNLYLIEVGRVKEAGAIEPW
YLLNGSLMVSAPDTLIVDQEFVVVPLDGWDTAVQAVRLGGRRTCDSDDLYPRSHRPALMLPEFQAGMVLAVCGVGAYQAM
IGGKGGAHHCLNPEMRRIIIEQDGDQLVMREIAPQNLMAQMSALGYSIATIEQPVRKPMPVRTAVVREQLPVRPLRTARR
RQAPSALRTSRFAASA

Sequences:

>Translated_576_residues
MSPDTWFFYAQKMDKALWESPSINTRTNTANFDCTLFSQPHVVAEHYRRGHHGLEGHVQLIEQTYAGYLNDSFGFSGAGA
LTDFLTRRNERLLLGDTVDLGALVEQFGAPLEVSFCPQITTQVQNMLDYAMAAQAASSYTGSFLYAYATKANFSEEVVRT
ALNAGAHYETSAAADVVIAHHLWRQGVLSEDRYIFCNGSKEPMYLDGILALRQAGYERVVAVLDDLDELDYILAHCRVPM
LFGVRERHAPDVVDRNHAGAERFGLTPAEMQLVAQRLAGTQHQLVVYHAMVGSQIEDAAAWEARLARSANAYAALASTTP
SLTMFNFGGGMPTSGYDLAFQFDYVGFLTNLMANTQAICAEHGVAAPMIIAECGRYTVANHNLYLIEVGRVKEAGAIEPW
YLLNGSLMVSAPDTLIVDQEFVVVPLDGWDTAVQAVRLGGRRTCDSDDLYPRSHRPALMLPEFQAGMVLAVCGVGAYQAM
IGGKGGAHHCLNPEMRRIIIEQDGDQLVMREIAPQNLMAQMSALGYSIATIEQPVRKPMPVRTAVVREQLPVRPLRTARR
RQAPSALRTSRFAASA
>Mature_575_residues
SPDTWFFYAQKMDKALWESPSINTRTNTANFDCTLFSQPHVVAEHYRRGHHGLEGHVQLIEQTYAGYLNDSFGFSGAGAL
TDFLTRRNERLLLGDTVDLGALVEQFGAPLEVSFCPQITTQVQNMLDYAMAAQAASSYTGSFLYAYATKANFSEEVVRTA
LNAGAHYETSAAADVVIAHHLWRQGVLSEDRYIFCNGSKEPMYLDGILALRQAGYERVVAVLDDLDELDYILAHCRVPML
FGVRERHAPDVVDRNHAGAERFGLTPAEMQLVAQRLAGTQHQLVVYHAMVGSQIEDAAAWEARLARSANAYAALASTTPS
LTMFNFGGGMPTSGYDLAFQFDYVGFLTNLMANTQAICAEHGVAAPMIIAECGRYTVANHNLYLIEVGRVKEAGAIEPWY
LLNGSLMVSAPDTLIVDQEFVVVPLDGWDTAVQAVRLGGRRTCDSDDLYPRSHRPALMLPEFQAGMVLAVCGVGAYQAMI
GGKGGAHHCLNPEMRRIIIEQDGDQLVMREIAPQNLMAQMSALGYSIATIEQPVRKPMPVRTAVVREQLPVRPLRTARRR
QAPSALRTSRFAASA

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=315, Percent_Identity=26.984126984127, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 63335; Mature: 63204

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDTWFFYAQKMDKALWESPSINTRTNTANFDCTLFSQPHVVAEHYRRGHHGLEGHVQL
CCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHH
IEQTYAGYLNDSFGFSGAGALTDFLTRRNERLLLGDTVDLGALVEQFGAPLEVSFCPQIT
HHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEECHHHH
TQVQNMLDYAMAAQAASSYTGSFLYAYATKANFSEEVVRTALNAGAHYETSAAADVVIAH
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
HLWRQGVLSEDRYIFCNGSKEPMYLDGILALRQAGYERVVAVLDDLDELDYILAHCRVPM
HHHHHCCCCCCCEEEECCCCCCEEHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHCCCHH
LFGVRERHAPDVVDRNHAGAERFGLTPAEMQLVAQRLAGTQHQLVVYHAMVGSQIEDAAA
HHCCHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEHHCCCHHHHHH
WEARLARSANAYAALASTTPSLTMFNFGGGMPTSGYDLAFQFDYVGFLTNLMANTQAICA
HHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHCHHHHHH
EHGVAAPMIIAECGRYTVANHNLYLIEVGRVKEAGAIEPWYLLNGSLMVSAPDTLIVDQE
HCCCCCHHHHHHCCCEEEECCCEEEEEECCCCCCCCCCCEEEECCEEEEECCCEEEECCC
FVVVPLDGWDTAVQAVRLGGRRTCDSDDLYPRSHRPALMLPEFQAGMVLAVCGVGAYQAM
EEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEECCCHHHHHH
IGGKGGAHHCLNPEMRRIIIEQDGDQLVMREIAPQNLMAQMSALGYSIATIEQPVRKPMP
HCCCCCCCCCCCHHHHEEEEECCCCHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHCCCC
VRTAVVREQLPVRPLRTARRRQAPSALRTSRFAASA
HHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SPDTWFFYAQKMDKALWESPSINTRTNTANFDCTLFSQPHVVAEHYRRGHHGLEGHVQL
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHH
IEQTYAGYLNDSFGFSGAGALTDFLTRRNERLLLGDTVDLGALVEQFGAPLEVSFCPQIT
HHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEECHHHH
TQVQNMLDYAMAAQAASSYTGSFLYAYATKANFSEEVVRTALNAGAHYETSAAADVVIAH
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
HLWRQGVLSEDRYIFCNGSKEPMYLDGILALRQAGYERVVAVLDDLDELDYILAHCRVPM
HHHHHCCCCCCCEEEECCCCCCEEHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHCCCHH
LFGVRERHAPDVVDRNHAGAERFGLTPAEMQLVAQRLAGTQHQLVVYHAMVGSQIEDAAA
HHCCHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEHHCCCHHHHHH
WEARLARSANAYAALASTTPSLTMFNFGGGMPTSGYDLAFQFDYVGFLTNLMANTQAICA
HHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHCHHHHHH
EHGVAAPMIIAECGRYTVANHNLYLIEVGRVKEAGAIEPWYLLNGSLMVSAPDTLIVDQE
HCCCCCHHHHHHCCCEEEECCCEEEEEECCCCCCCCCCCEEEECCEEEEECCCEEEECCC
FVVVPLDGWDTAVQAVRLGGRRTCDSDDLYPRSHRPALMLPEFQAGMVLAVCGVGAYQAM
EEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEECCCHHHHHH
IGGKGGAHHCLNPEMRRIIIEQDGDQLVMREIAPQNLMAQMSALGYSIATIEQPVRKPMP
HCCCCCCCCCCCHHHHEEEEECCCCHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHCCCC
VRTAVVREQLPVRPLRTARRRQAPSALRTSRFAASA
HHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]