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The map label for this gene is pheA [H]

Identifier: 159900958

GI number: 159900958

Start: 5686415

End: 5687239

Strand: Reverse

Name: pheA [H]

Synonym: Haur_4445

Alternate gene names: 159900958

Gene position: 5687239-5686415 (Counterclockwise)

Preceding gene: 159900959

Following gene: 159900957

Centisome position: 89.61

GC content: 52.61

Gene sequence:

>825_bases
ATGAAAATTGCTTATCTTGGCCCGGCTGGTACATTCAGCGAAAAAGCAGCGTTGGAAACGGGCGACCAACAATCCACCTA
TTTGCCAATGGCAAGTATGCCCGCTGTGATTACGGCTGTTGAAACTCGTGCGGTTGATTTAGGCATTTTGCCAATTGAAA
ACTCGCTCGAAGGGGCGGTCAGCGTTACGCTTGATGTGCTGATTCACGAAACGCGTCTGCGGATTTGCCGCGAAATCGTG
ATTCCGATTCGGCATATGGTGGTGGCCAAGCCCGATGTGCAACTCGATACGGTCGAAGTGCTCTACACCCATCAACAACC
GCTAGCTCAATCGCGCCGTTTTATCGAACGTTGCTTGCCGAATGTGCCAACCGTGGCCGCGTTAAGCACTGCTGCTGCAT
TGGTCGAAGCGCTCGCCGATGAGCGCCGCGCCGCCGCATTGACCACCTTGCATGCTGCCGAACGCGCCCAAGCCAATATC
TTGGCCTACGATGTTCAGGATAACAACAATAATCGCACGCGCTTTGTGGTGTTGGCTCCTGAGGATGCCGCACCAACGGG
TGACGACAAGACTTCGCTGATGTTCACTGCCAAAGTTAATCGCGCAGGAGCGTTATACGAAGCCTTGGCAATTTTCGCCC
AAGCTGGGATCAATTTGAGCAAAATTGAATCGCGGCCAGCCAAAGCCGAGCTTGGCGATTATGTCTTTCTGGTTGATATC
GATGGCCATCGCCATGAACCAGTTGTTGCCGAAGCCCTACAAAAGCTGGCACAGATCGCTGGCACAGTCAAGATTTTTGG
TAGCTATCCAAAGTTTCGCGGATAA

Upstream 100 bases:

>100_bases
GCGCTGCGCCAGGCGTGGATTTGTTCGGTGGCTCGACCCTTGGACGGTATGAATAATTGCTGAGGTTGGGTCAAATCAAC
CTCGCTAGCCCAAAGAACTT

Downstream 100 bases:

>100_bases
ACCGCAAAAACGCGAAGGCCGATCCACGAAGAACACGAAGGACACTAAGCTTCAACGTACTAACCTTCGTGCTCTTTGTG
CCCTTCGTGGATCAATCGAA

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKIAYLGPAGTFSEKAALETGDQQSTYLPMASMPAVITAVETRAVDLGILPIENSLEGAVSVTLDVLIHETRLRICREIV
IPIRHMVVAKPDVQLDTVEVLYTHQQPLAQSRRFIERCLPNVPTVAALSTAAALVEALADERRAAALTTLHAAERAQANI
LAYDVQDNNNNRTRFVVLAPEDAAPTGDDKTSLMFTAKVNRAGALYEALAIFAQAGINLSKIESRPAKAELGDYVFLVDI
DGHRHEPVVAEALQKLAQIAGTVKIFGSYPKFRG

Sequences:

>Translated_274_residues
MKIAYLGPAGTFSEKAALETGDQQSTYLPMASMPAVITAVETRAVDLGILPIENSLEGAVSVTLDVLIHETRLRICREIV
IPIRHMVVAKPDVQLDTVEVLYTHQQPLAQSRRFIERCLPNVPTVAALSTAAALVEALADERRAAALTTLHAAERAQANI
LAYDVQDNNNNRTRFVVLAPEDAAPTGDDKTSLMFTAKVNRAGALYEALAIFAQAGINLSKIESRPAKAELGDYVFLVDI
DGHRHEPVVAEALQKLAQIAGTVKIFGSYPKFRG
>Mature_274_residues
MKIAYLGPAGTFSEKAALETGDQQSTYLPMASMPAVITAVETRAVDLGILPIENSLEGAVSVTLDVLIHETRLRICREIV
IPIRHMVVAKPDVQLDTVEVLYTHQQPLAQSRRFIERCLPNVPTVAALSTAAALVEALADERRAAALTTLHAAERAQANI
LAYDVQDNNNNRTRFVVLAPEDAAPTGDDKTSLMFTAKVNRAGALYEALAIFAQAGINLSKIESRPAKAELGDYVFLVDI
DGHRHEPVVAEALQKLAQIAGTVKIFGSYPKFRG

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=287, Percent_Identity=31.3588850174216, Blast_Score=119, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324013, Length=324, Percent_Identity=23.1481481481481, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 29667; Mature: 29667

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAYLGPAGTFSEKAALETGDQQSTYLPMASMPAVITAVETRAVDLGILPIENSLEGAV
CEEEEECCCCCCCCHHHHCCCCCCCEECCCHHCCHHEEEHHHEEEEEEEEECCCCCCCHH
SVTLDVLIHETRLRICREIVIPIRHMVVAKPDVQLDTVEVLYTHQQPLAQSRRFIERCLP
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHCC
NVPTVAALSTAAALVEALADERRAAALTTLHAAERAQANILAYDVQDNNNNRTRFVVLAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEEEEC
EDAAPTGDDKTSLMFTAKVNRAGALYEALAIFAQAGINLSKIESRPAKAELGDYVFLVDI
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEEE
DGHRHEPVVAEALQKLAQIAGTVKIFGSYPKFRG
CCCCCCCHHHHHHHHHHHHHCEEEEEECCCCCCC
>Mature Secondary Structure
MKIAYLGPAGTFSEKAALETGDQQSTYLPMASMPAVITAVETRAVDLGILPIENSLEGAV
CEEEEECCCCCCCCHHHHCCCCCCCEECCCHHCCHHEEEHHHEEEEEEEEECCCCCCCHH
SVTLDVLIHETRLRICREIVIPIRHMVVAKPDVQLDTVEVLYTHQQPLAQSRRFIERCLP
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHCC
NVPTVAALSTAAALVEALADERRAAALTTLHAAERAQANILAYDVQDNNNNRTRFVVLAP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEEEEC
EDAAPTGDDKTSLMFTAKVNRAGALYEALAIFAQAGINLSKIESRPAKAELGDYVFLVDI
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEEE
DGHRHEPVVAEALQKLAQIAGTVKIFGSYPKFRG
CCCCCCCHHHHHHHHHHHHHCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]