Click here to switch to the map view.

The map label for this gene is pimA [H]

Identifier: 159900841

GI number: 159900841

Start: 5527629

End: 5528774

Strand: Direct

Name: pimA [H]

Synonym: Haur_4328

Alternate gene names: 159900841

Gene position: 5527629-5528774 (Clockwise)

Preceding gene: 159900837

Following gene: 159900842

Centisome position: 87.1

GC content: 49.3

Gene sequence:

>1146_bases
ATGAAAATTGGCTTTTTGATTGATGATCATATGCACCGCGCTGGGGGCATTCAGGTATATGTTCGTGGTTTGTATCATTA
TTTTCAAAGCAAAGGTCATGAGGTGGTGATTTTTGCTGGTGGTAGTCAGTTTGATAATAGCAAATTGGCTGAGCGCGTTA
TCTCGTTGGGCGTTTCAATTCCGACGTATGGCAGCGGTTCGAGTACATCACTGCCAATCTGCATCGAATCGAATCGCCGC
TTGCGCGAGATTTTAGCCGAAGAAGCTTGTGATGTTTTGCATGTTCAATCGTTGCACTCGCCTACCTTGAGCGGGCGACT
TTTGGCGAATTCCAAGGCTTGCCATGTTTCAACCTTTCATATTCGGGTTGATGAGGCGTGGAAATTGCAGGCCTTGCGTT
TGGCAACCGCACTTGGCCCCGATTTATATCGCCATATCCATGGGCGAATTGCTGGATCACAGGCGGCACTCGAAACAGCG
CAGGCAATTTTTGGCACCAAAGACGAGTATACAATTATTGCCAGTGGCATAACGATTGATCGCTTTGATGCAGCGGTGAA
TTTGCCACGCTTGCATCAATATAACGATGATAAAATTACGCTCTTTACGCTTGGGCGCTTGGAGCAACGCAAGGGCGTGG
AGTATCTGCTGCGAGCTTATGCCTTGCTCCAAAAGGATTATCCCAACCAATTGCGCTTGGTGATTGCTGGCGATGGGCCA
TTACGCGAAGAATTACAAGCCTTGGCAGCCCAATTGCGCTTGACCGATGTCGAATGGCTGGGCTATGTGACCGATTTGGC
CTTGCCGCATTTGATGGCGAGTGCTGATATTTTTTGTGCACCAGCGATTGGCCAAGAGAGCTTTGGTTATGTATTGATTG
AGGCCATGGCGGTTGGTTTGCCAGTTGTGGCGGCAGCTAATGCAGGCTATGCGGGAGTTTTGGCCAATCATCCAGGTAAT
TTAGCAGTGCCACCACGCGATCCACGGGCAATGGCTGGGGCGATTGCCAGTTTTGTTGCCAGCCCTGCCGCCCGCAAACG
TCTGCGCCAACTAAATCTACAAGCGGCCAAAGGCTATAGTTGGCAGGTGATTGGCGACCAAATTATGGAATTCTACAAAA
AAACAATGGCGCAAACTGTGCAATAG

Upstream 100 bases:

>100_bases
ATCTCTAACTCCTGATCCCTGACTCCTAGCCCTCTACTGCTTGACATTTTCGCCATGGTAGCGCAGATTGATCCAGGATT
ATTTTGATTTAGGTTGATCT

Downstream 100 bases:

>100_bases
TACCAAGTGCTTAGGCGGTTTTTTGTGTAGTTTGCATAACAGGTGCTTAATAATCTTGTGCTATAGTATGGCTATGCCAA
CGGTGGCAACGAACCCCAAT

Product: phosphatidylinositol alpha-mannosyltransferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKIGFLIDDHMHRAGGIQVYVRGLYHYFQSKGHEVVIFAGGSQFDNSKLAERVISLGVSIPTYGSGSSTSLPICIESNRR
LREILAEEACDVLHVQSLHSPTLSGRLLANSKACHVSTFHIRVDEAWKLQALRLATALGPDLYRHIHGRIAGSQAALETA
QAIFGTKDEYTIIASGITIDRFDAAVNLPRLHQYNDDKITLFTLGRLEQRKGVEYLLRAYALLQKDYPNQLRLVIAGDGP
LREELQALAAQLRLTDVEWLGYVTDLALPHLMASADIFCAPAIGQESFGYVLIEAMAVGLPVVAAANAGYAGVLANHPGN
LAVPPRDPRAMAGAIASFVASPAARKRLRQLNLQAAKGYSWQVIGDQIMEFYKKTMAQTVQ

Sequences:

>Translated_381_residues
MKIGFLIDDHMHRAGGIQVYVRGLYHYFQSKGHEVVIFAGGSQFDNSKLAERVISLGVSIPTYGSGSSTSLPICIESNRR
LREILAEEACDVLHVQSLHSPTLSGRLLANSKACHVSTFHIRVDEAWKLQALRLATALGPDLYRHIHGRIAGSQAALETA
QAIFGTKDEYTIIASGITIDRFDAAVNLPRLHQYNDDKITLFTLGRLEQRKGVEYLLRAYALLQKDYPNQLRLVIAGDGP
LREELQALAAQLRLTDVEWLGYVTDLALPHLMASADIFCAPAIGQESFGYVLIEAMAVGLPVVAAANAGYAGVLANHPGN
LAVPPRDPRAMAGAIASFVASPAARKRLRQLNLQAAKGYSWQVIGDQIMEFYKKTMAQTVQ
>Mature_381_residues
MKIGFLIDDHMHRAGGIQVYVRGLYHYFQSKGHEVVIFAGGSQFDNSKLAERVISLGVSIPTYGSGSSTSLPICIESNRR
LREILAEEACDVLHVQSLHSPTLSGRLLANSKACHVSTFHIRVDEAWKLQALRLATALGPDLYRHIHGRIAGSQAALETA
QAIFGTKDEYTIIASGITIDRFDAAVNLPRLHQYNDDKITLFTLGRLEQRKGVEYLLRAYALLQKDYPNQLRLVIAGDGP
LREELQALAAQLRLTDVEWLGYVTDLALPHLMASADIFCAPAIGQESFGYVLIEAMAVGLPVVAAANAGYAGVLANHPGN
LAVPPRDPRAMAGAIASFVASPAARKRLRQLNLQAAKGYSWQVIGDQIMEFYKKTMAQTVQ

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Contrary to pimB, the mannosyltransferase pim

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 41673; Mature: 41673

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGFLIDDHMHRAGGIQVYVRGLYHYFQSKGHEVVIFAGGSQFDNSKLAERVISLGVSI
CEEEEEECCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCC
PTYGSGSSTSLPICIESNRRLREILAEEACDVLHVQSLHSPTLSGRLLANSKACHVSTFH
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEE
IRVDEAWKLQALRLATALGPDLYRHIHGRIAGSQAALETAQAIFGTKDEYTIIASGITID
EEECCCHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCEEE
RFDAAVNLPRLHQYNDDKITLFTLGRLEQRKGVEYLLRAYALLQKDYPNQLRLVIAGDGP
HHHHHCCCCHHCCCCCCEEEEEEECCHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCCC
LREELQALAAQLRLTDVEWLGYVTDLALPHLMASADIFCAPAIGQESFGYVLIEAMAVGL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCC
PVVAAANAGYAGVLANHPGNLAVPPRDPRAMAGAIASFVASPAARKRLRQLNLQAAKGYS
CEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHCCCCE
WQVIGDQIMEFYKKTMAQTVQ
EEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIGFLIDDHMHRAGGIQVYVRGLYHYFQSKGHEVVIFAGGSQFDNSKLAERVISLGVSI
CEEEEEECCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCC
PTYGSGSSTSLPICIESNRRLREILAEEACDVLHVQSLHSPTLSGRLLANSKACHVSTFH
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEE
IRVDEAWKLQALRLATALGPDLYRHIHGRIAGSQAALETAQAIFGTKDEYTIIASGITID
EEECCCHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCEEE
RFDAAVNLPRLHQYNDDKITLFTLGRLEQRKGVEYLLRAYALLQKDYPNQLRLVIAGDGP
HHHHHCCCCHHCCCCCCEEEEEEECCHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCCC
LREELQALAAQLRLTDVEWLGYVTDLALPHLMASADIFCAPAIGQESFGYVLIEAMAVGL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCC
PVVAAANAGYAGVLANHPGNLAVPPRDPRAMAGAIASFVASPAARKRLRQLNLQAAKGYS
CEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHCCCCE
WQVIGDQIMEFYKKTMAQTVQ
EEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12068013 [H]