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The map label for this gene is mshA [H]

Identifier: 159900784

GI number: 159900784

Start: 5452131

End: 5453240

Strand: Direct

Name: mshA [H]

Synonym: Haur_4271

Alternate gene names: 159900784

Gene position: 5452131-5453240 (Clockwise)

Preceding gene: 159900783

Following gene: 159900785

Centisome position: 85.91

GC content: 53.42

Gene sequence:

>1110_bases
ATGCATATTATTCACTACAATCTGACGACTACTAGCAAAGTCGGCGGGGTTGAGAGTTTTGTTTGGGAATTGGCGCAGCA
GCAAGTTCGGCTCGGCCATCGGGTGACGATTGTTGGTGGTCAAGGCCCAATTCAACGGCCAAATCAGGGCTTGCGGGTGC
TAAAATTCCCATTTATTGATCGGGCACGTTTGGCTTGGGGGCCGTTACGTCGCGCTTATGCTTGGCGCAAATTGGCCGAA
CGCTTGTCGCTGCTGCCACGGGCTTGGCCTATTTTGAAAACTGCCGATTTGGTGCATATTCACAAGCCTTATGATTTGGT
CGTGGCTCCATTGCTCAAACGCCATGGCATTCCCACGGCTTATCACGGCCATGGCGAAGATTTTTTTCGCGGCGATGTTC
AGCTGATGCAGTCAGCCGCCGTGCTGCTTTCGTGCTCTAGCTACAATGCCCAAACCTTGCAGCAACATTATGGGCGCACG
GCGAGCGTGGTCTATAACGGCGTTGATGTCGAGCATTTTCGACCTTTGGCGCTAGATCCAGCATTACGCCAAGCAATTGC
TGGCGATGCTCAATGGTTATTGATGCATCCTGGGCGCATGATGCCTTGGAAAGGTCAGCGCGATGCAATTAGTGCCTTGA
GTTTGCTCGATCACACCTATCATTTGGCCTTTTTAGGCGATGGCGAAACCCGCCAAGCCTTGGCTGACTATGCCCAACAA
TTAGGCATTGCCGAACGCGTGCACTTTCTTGGCACAATTGCCCACAGCGAATTGCCGCGCTATTTGGCCTGCGCCGATTT
GGTGCTTGGTACGAGTTATACATCAGAGACGTTTGGCATGGCCTTAGCCGAAGCCCAAGCCTGTGGCCGGCCCGTTATCG
CCTCGTCGTGGCGTGGTTATGATGATGTGGTGCAAGCTGGCAGCACTGGCGAACGCTTTATCGCCCAAAATTCAGCCGAT
TTAGCTCGCGTTATCAGCCAACTTTGCCACGATTCAGCCTATCGTGAGCAACTAGCGCGTGCTGGTCGCCAACGGGTGCA
ACAATTGTTCCCGTGGTCGGCTGTCGCCGAGCGAGTTGAAGTGGTGTATGAGGGGTTAGTTAGTTGCTAG

Upstream 100 bases:

>100_bases
GCAAACTGCGCGATTTGGCTTATCGGCTTGGTTTAGGCTTGCCTGCTTATTATTTTTACCGTGATTGGGTCAAGGGAACC
TACGAATTGGTGCTGTGGTA

Downstream 100 bases:

>100_bases
GGGTCAGGGGCCAGAGAATAGCGACGAGATTTAACGCAGAGACACAGAAAGCCAAAGGATGAATTATGAGGGATAAGGGA
TGAAATTATAACAGGATTGG

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MHIIHYNLTTTSKVGGVESFVWELAQQQVRLGHRVTIVGGQGPIQRPNQGLRVLKFPFIDRARLAWGPLRRAYAWRKLAE
RLSLLPRAWPILKTADLVHIHKPYDLVVAPLLKRHGIPTAYHGHGEDFFRGDVQLMQSAAVLLSCSSYNAQTLQQHYGRT
ASVVYNGVDVEHFRPLALDPALRQAIAGDAQWLLMHPGRMMPWKGQRDAISALSLLDHTYHLAFLGDGETRQALADYAQQ
LGIAERVHFLGTIAHSELPRYLACADLVLGTSYTSETFGMALAEAQACGRPVIASSWRGYDDVVQAGSTGERFIAQNSAD
LARVISQLCHDSAYREQLARAGRQRVQQLFPWSAVAERVEVVYEGLVSC

Sequences:

>Translated_369_residues
MHIIHYNLTTTSKVGGVESFVWELAQQQVRLGHRVTIVGGQGPIQRPNQGLRVLKFPFIDRARLAWGPLRRAYAWRKLAE
RLSLLPRAWPILKTADLVHIHKPYDLVVAPLLKRHGIPTAYHGHGEDFFRGDVQLMQSAAVLLSCSSYNAQTLQQHYGRT
ASVVYNGVDVEHFRPLALDPALRQAIAGDAQWLLMHPGRMMPWKGQRDAISALSLLDHTYHLAFLGDGETRQALADYAQQ
LGIAERVHFLGTIAHSELPRYLACADLVLGTSYTSETFGMALAEAQACGRPVIASSWRGYDDVVQAGSTGERFIAQNSAD
LARVISQLCHDSAYREQLARAGRQRVQQLFPWSAVAERVEVVYEGLVSC
>Mature_369_residues
MHIIHYNLTTTSKVGGVESFVWELAQQQVRLGHRVTIVGGQGPIQRPNQGLRVLKFPFIDRARLAWGPLRRAYAWRKLAE
RLSLLPRAWPILKTADLVHIHKPYDLVVAPLLKRHGIPTAYHGHGEDFFRGDVQLMQSAAVLLSCSSYNAQTLQQHYGRT
ASVVYNGVDVEHFRPLALDPALRQAIAGDAQWLLMHPGRMMPWKGQRDAISALSLLDHTYHLAFLGDGETRQALADYAQQ
LGIAERVHFLGTIAHSELPRYLACADLVLGTSYTSETFGMALAEAQACGRPVIASSWRGYDDVVQAGSTGERFIAQNSAD
LARVISQLCHDSAYREQLARAGRQRVQQLFPWSAVAERVEVVYEGLVSC

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=382, Percent_Identity=25.3926701570681, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17532709, Length=388, Percent_Identity=23.7113402061856, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654571, Length=315, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814
- InterPro:   IPR013534 [H]

Pfam domain/function: PF08323 Glyco_transf_5; PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 41108; Mature: 41108

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIIHYNLTTTSKVGGVESFVWELAQQQVRLGHRVTIVGGQGPIQRPNQGLRVLKFPFID
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEECCCCC
RARLAWGPLRRAYAWRKLAERLSLLPRAWPILKTADLVHIHKPYDLVVAPLLKRHGIPTA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEECCCHHHHHHHHHHHCCCCCE
YHGHGEDFFRGDVQLMQSAAVLLSCSSYNAQTLQQHYGRTASVVYNGVDVEHFRPLALDP
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEECCCCHHHCCCCCCCH
ALRQAIAGDAQWLLMHPGRMMPWKGQRDAISALSLLDHTYHLAFLGDGETRQALADYAQQ
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHH
LGIAERVHFLGTIAHSELPRYLACADLVLGTSYTSETFGMALAEAQACGRPVIASSWRGY
HCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCH
DDVVQAGSTGERFIAQNSADLARVISQLCHDSAYREQLARAGRQRVQQLFPWSAVAERVE
HHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VVYEGLVSC
HHHHHHHCC
>Mature Secondary Structure
MHIIHYNLTTTSKVGGVESFVWELAQQQVRLGHRVTIVGGQGPIQRPNQGLRVLKFPFID
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEECCCCC
RARLAWGPLRRAYAWRKLAERLSLLPRAWPILKTADLVHIHKPYDLVVAPLLKRHGIPTA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEECCCHHHHHHHHHHHCCCCCE
YHGHGEDFFRGDVQLMQSAAVLLSCSSYNAQTLQQHYGRTASVVYNGVDVEHFRPLALDP
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEECCCCHHHCCCCCCCH
ALRQAIAGDAQWLLMHPGRMMPWKGQRDAISALSLLDHTYHLAFLGDGETRQALADYAQQ
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHH
LGIAERVHFLGTIAHSELPRYLACADLVLGTSYTSETFGMALAEAQACGRPVIASSWRGY
HCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCH
DDVVQAGSTGERFIAQNSADLARVISQLCHDSAYREQLARAGRQRVQQLFPWSAVAERVE
HHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VVYEGLVSC
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA