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The map label for this gene is yrpG [H]

Identifier: 159900732

GI number: 159900732

Start: 5376302

End: 5377279

Strand: Direct

Name: yrpG [H]

Synonym: Haur_4219

Alternate gene names: 159900732

Gene position: 5376302-5377279 (Clockwise)

Preceding gene: 159900730

Following gene: 159900733

Centisome position: 84.71

GC content: 51.74

Gene sequence:

>978_bases
ATGCGCTATCGCAAATTAGGCCGAACTGGACTCAAAGTTTCGGAATTATGTTTGGGAACAATGACCTTTGGCTGGAGTGT
TGAAGAGCCAGAATCGTTCGCGATTATGAGCCAAGCGCTGGATGCAGGCATTAATTTCTTCGATACTGCCGATGTTTATT
CGCGTTGGGACCCCCGTTCATATGCTGGCAAAACCGAGGAAATTATCGGGCGTTGGTTGGCCGAGGAGCCAAGTCGTCGC
GATAAAGTGGTGTTAGCAACCAAAGTTCGTGGCCAAATGGGCGATCAGCCGAACGATCAAGGGCTGTCGCGCAAACATAT
TATTGCAGCGGTTGATGCCAGCTTGCGGCGCTTGCAAACAGATTATATCGACCTCTATCAAACCCACTTTCCCGATAGCG
AAGTGCCAATCGAAGAAACCTTGCGGGCGCTTGATGATTTGGTACGAGCTGGTAAAGTGCGCTATATCGGCTGCTCGAAT
TACCGCGCATGGCAATTGATCGAAGCCCTGTGGACAAGCGATAAACTGAATCTCGCCCGTTACGATTCGCTGCAACCACA
TTATCATTTGCTCAATCGAGCCGAGTTTGAGCGCGAATTACAACCAGTTTGCGCCAAGTATGGCGTGGGCGTGATTGTCT
ATAGCCCGTTGGCGGGTGGCTTATTGACTGGCAAGTTTCGGCGTGGCCAGCCTATCCCCGAGGGCACACGGGTTGCTGAA
CGTGGCCGTGACGACAAACGCCTGAGCGAACCATTGTGGAAATTAATCGATCAGCTGGAAGTGTTAGCTGAGAAGCACCA
AAAAACCATTCCCCAACTGGCAGTGGCATGGGTCACGGGTGCACCAGCGATCACCTCGGCGATTATTGGGGCAACCAGCA
GTGGGCAACTCCACGATACCTTGGGTGCAGCCGATTTTGAGTTGAGTAGCGAAGATCGGGCCATTTTAGACAACCTAAGT
GCTTGGGAGAACGTCTAA

Upstream 100 bases:

>100_bases
GTAGGATACTGTATGAATGACGAATTATGAGGGAGGAAGGTCAAGCCAAACGCCAATAGCCTTACTTCGTGGTTCATATC
ATTAACAAGGAGCAATCACC

Downstream 100 bases:

>100_bases
ACATCATTCGGATGGCCGACGAAGCTCCATCGTAAGATTGGTTTTTGCTGAGAAACGTTGCCAAGGCGTAGGGGCAATGA
TACAATACCACGGGCAACTA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRYRKLGRTGLKVSELCLGTMTFGWSVEEPESFAIMSQALDAGINFFDTADVYSRWDPRSYAGKTEEIIGRWLAEEPSRR
DKVVLATKVRGQMGDQPNDQGLSRKHIIAAVDASLRRLQTDYIDLYQTHFPDSEVPIEETLRALDDLVRAGKVRYIGCSN
YRAWQLIEALWTSDKLNLARYDSLQPHYHLLNRAEFERELQPVCAKYGVGVIVYSPLAGGLLTGKFRRGQPIPEGTRVAE
RGRDDKRLSEPLWKLIDQLEVLAEKHQKTIPQLAVAWVTGAPAITSAIIGATSSGQLHDTLGAADFELSSEDRAILDNLS
AWENV

Sequences:

>Translated_325_residues
MRYRKLGRTGLKVSELCLGTMTFGWSVEEPESFAIMSQALDAGINFFDTADVYSRWDPRSYAGKTEEIIGRWLAEEPSRR
DKVVLATKVRGQMGDQPNDQGLSRKHIIAAVDASLRRLQTDYIDLYQTHFPDSEVPIEETLRALDDLVRAGKVRYIGCSN
YRAWQLIEALWTSDKLNLARYDSLQPHYHLLNRAEFERELQPVCAKYGVGVIVYSPLAGGLLTGKFRRGQPIPEGTRVAE
RGRDDKRLSEPLWKLIDQLEVLAEKHQKTIPQLAVAWVTGAPAITSAIIGATSSGQLHDTLGAADFELSSEDRAILDNLS
AWENV
>Mature_325_residues
MRYRKLGRTGLKVSELCLGTMTFGWSVEEPESFAIMSQALDAGINFFDTADVYSRWDPRSYAGKTEEIIGRWLAEEPSRR
DKVVLATKVRGQMGDQPNDQGLSRKHIIAAVDASLRRLQTDYIDLYQTHFPDSEVPIEETLRALDDLVRAGKVRYIGCSN
YRAWQLIEALWTSDKLNLARYDSLQPHYHLLNRAEFERELQPVCAKYGVGVIVYSPLAGGLLTGKFRRGQPIPEGTRVAE
RGRDDKRLSEPLWKLIDQLEVLAEKHQKTIPQLAVAWVTGAPAITSAIIGATSSGQLHDTLGAADFELSSEDRAILDNLS
AWENV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=310, Percent_Identity=37.0967741935484, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI4504825, Length=308, Percent_Identity=37.012987012987, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI27436964, Length=335, Percent_Identity=35.5223880597015, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI27436962, Length=335, Percent_Identity=35.5223880597015, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI27436966, Length=335, Percent_Identity=35.2238805970149, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI27436971, Length=311, Percent_Identity=35.3697749196142, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI223718702, Length=318, Percent_Identity=30.8176100628931, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI41152114, Length=339, Percent_Identity=28.6135693215339, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI41327764, Length=283, Percent_Identity=30.7420494699647, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI223718708, Length=151, Percent_Identity=34.4370860927152, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI87081735, Length=332, Percent_Identity=42.1686746987952, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1789199, Length=333, Percent_Identity=37.5375375375375, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789375, Length=342, Percent_Identity=33.9181286549708, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1788070, Length=342, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=29.5774647887324, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786400, Length=278, Percent_Identity=24.4604316546763, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564128, Length=337, Percent_Identity=27.299703264095, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=323, Percent_Identity=23.8390092879257, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=356, Percent_Identity=25.8426966292135, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=345, Percent_Identity=32.7536231884058, Blast_Score=166, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6323998, Length=337, Percent_Identity=28.7833827893175, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319958, Length=306, Percent_Identity=26.4705882352941, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=299, Percent_Identity=28.0936454849498, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=253, Percent_Identity=25.6916996047431, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=172, Percent_Identity=31.3953488372093, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640980, Length=326, Percent_Identity=30.0613496932515, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI45549126, Length=330, Percent_Identity=30.3030303030303, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24646155, Length=334, Percent_Identity=28.4431137724551, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646159, Length=340, Percent_Identity=28.5294117647059, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24663317, Length=339, Percent_Identity=25.0737463126844, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644950, Length=335, Percent_Identity=27.1641791044776, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36490; Mature: 36490

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYRKLGRTGLKVSELCLGTMTFGWSVEEPESFAIMSQALDAGINFFDTADVYSRWDPRS
CCCHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCHH
YAGKTEEIIGRWLAEEPSRRDKVVLATKVRGQMGDQPNDQGLSRKHIIAAVDASLRRLQT
HCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DYIDLYQTHFPDSEVPIEETLRALDDLVRAGKVRYIGCSNYRAWQLIEALWTSDKLNLAR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCHHH
YDSLQPHYHLLNRAEFERELQPVCAKYGVGVIVYSPLAGGLLTGKFRRGQPIPEGTRVAE
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCCCCCCCCCHHHHH
RGRDDKRLSEPLWKLIDQLEVLAEKHQKTIPQLAVAWVTGAPAITSAIIGATSSGQLHDT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHH
LGAADFELSSEDRAILDNLSAWENV
HCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRYRKLGRTGLKVSELCLGTMTFGWSVEEPESFAIMSQALDAGINFFDTADVYSRWDPRS
CCCHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCHH
YAGKTEEIIGRWLAEEPSRRDKVVLATKVRGQMGDQPNDQGLSRKHIIAAVDASLRRLQT
HCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DYIDLYQTHFPDSEVPIEETLRALDDLVRAGKVRYIGCSNYRAWQLIEALWTSDKLNLAR
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCHHH
YDSLQPHYHLLNRAEFERELQPVCAKYGVGVIVYSPLAGGLLTGKFRRGQPIPEGTRVAE
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCCCCCCCCCHHHHH
RGRDDKRLSEPLWKLIDQLEVLAEKHQKTIPQLAVAWVTGAPAITSAIIGATSSGQLHDT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHH
LGAADFELSSEDRAILDNLSAWENV
HCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]