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The map label for this gene is rsmA [H]

Identifier: 159900605

GI number: 159900605

Start: 5224498

End: 5225364

Strand: Reverse

Name: rsmA [H]

Synonym: Haur_4092

Alternate gene names: 159900605

Gene position: 5225364-5224498 (Counterclockwise)

Preceding gene: 159900606

Following gene: 159900601

Centisome position: 82.33

GC content: 53.29

Gene sequence:

>867_bases
ATGAATCCATATACCGATCCGTCGCGGGTGCGCGGAGCTTTAAATAGCATCGGGGTGCGCCCGAGCAAAAGCATGGGCCA
GAATTTTTTGATCGATCCTACGCCGCTCAAGTTGGCCTTGGAACATGCTGAAGTCAATCCTAATGATGTGGTGGTTGAGG
TCGGGCCTGGTTTGGGCGTGCTGACTTGGGAATTATTGAATGCCGCTGGTCACGTGATTAGCATTGAGCTTGATCCGCGA
TTGGCTGGACGCTTGCGCACCGAATTTGCCGAGCGCCCTTTGACGATTGTTGAAAGCGATGTGCTGGAAATTGCTCCTAG
CGCGATGTTGGCGGCGGCTGGTTTGCCCGCCGATACATCTTATAAATTGGTGGCAAATATTCCCTATGCGATTACGTCGC
CCTTGTTGCGCCATTTTCTTGAAGGCGATAGCCCGCCTAGCTTGATGATGGTGTTGATGCAGTGGGAAGTTGCCGATCGC
ATTACGGCTAAACCAGGCGATCTGAGTATTTTGGCGCATAGTGTGCAACTCTATGCTACTGCTGAAATTATTGCGCGGGT
GCCAGCCGCTTCGTTCTTGCCCGCGCCGGCTGTCGATTCGGCGTTAGTGCTGATGCGCCGCCGTGCTACCAACGCTGTGC
CGACTGCACCCAAAGCTTTGTTTAAGGTGATTCGCGCAGGGTTTAGCCAAGCCCGTAAAAAGCTGATCAATTCGTTGGCT
GGTGGTTTGGCTGGTCAAGGCTTTGGCAAGGAGCAAGTGCTGGCGGCAATTGTTCAGGCCGAAATTGACCCTAATTTGCG
AGCCGAGGTGCTGACCTTGGAGCAATGGGCCAGATTAACTGAAACGCTGGGCCTTGCTACCAAATAA

Upstream 100 bases:

>100_bases
GGAATGCCCCTCGCCCGCCGCAGTGGGAGAGGGGTGGGGGTGAGGGCATGTTACATCCAACAAGAAACAGGTATACTACT
ACTCTAATTAAGGAGTAATA

Downstream 100 bases:

>100_bases
TTAAGCCGCGTTGAGCGCCAACCCGAATCGCTTCAGTCCGCGAGCTAACATCCAACTTGCCGAGCAACGCTGAAACATGA
AATTTCACGGTATGCTCGCT

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNPYTDPSRVRGALNSIGVRPSKSMGQNFLIDPTPLKLALEHAEVNPNDVVVEVGPGLGVLTWELLNAAGHVISIELDPR
LAGRLRTEFAERPLTIVESDVLEIAPSAMLAAAGLPADTSYKLVANIPYAITSPLLRHFLEGDSPPSLMMVLMQWEVADR
ITAKPGDLSILAHSVQLYATAEIIARVPAASFLPAPAVDSALVLMRRRATNAVPTAPKALFKVIRAGFSQARKKLINSLA
GGLAGQGFGKEQVLAAIVQAEIDPNLRAEVLTLEQWARLTETLGLATK

Sequences:

>Translated_288_residues
MNPYTDPSRVRGALNSIGVRPSKSMGQNFLIDPTPLKLALEHAEVNPNDVVVEVGPGLGVLTWELLNAAGHVISIELDPR
LAGRLRTEFAERPLTIVESDVLEIAPSAMLAAAGLPADTSYKLVANIPYAITSPLLRHFLEGDSPPSLMMVLMQWEVADR
ITAKPGDLSILAHSVQLYATAEIIARVPAASFLPAPAVDSALVLMRRRATNAVPTAPKALFKVIRAGFSQARKKLINSLA
GGLAGQGFGKEQVLAAIVQAEIDPNLRAEVLTLEQWARLTETLGLATK
>Mature_288_residues
MNPYTDPSRVRGALNSIGVRPSKSMGQNFLIDPTPLKLALEHAEVNPNDVVVEVGPGLGVLTWELLNAAGHVISIELDPR
LAGRLRTEFAERPLTIVESDVLEIAPSAMLAAAGLPADTSYKLVANIPYAITSPLLRHFLEGDSPPSLMMVLMQWEVADR
ITAKPGDLSILAHSVQLYATAEIIARVPAASFLPAPAVDSALVLMRRRATNAVPTAPKALFKVIRAGFSQARKKLINSLA
GGLAGQGFGKEQVLAAIVQAEIDPNLRAEVLTLEQWARLTETLGLATK

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

Organism=Homo sapiens, GI7657198, Length=193, Percent_Identity=34.1968911917098, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI156415992, Length=292, Percent_Identity=27.3972602739726, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786236, Length=268, Percent_Identity=31.7164179104478, Blast_Score=107, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI25146882, Length=180, Percent_Identity=34.4444444444444, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324989, Length=186, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21358017, Length=198, Percent_Identity=32.8282828282828, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21357273, Length=298, Percent_Identity=28.1879194630872, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 30798; Mature: 30798

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS01131 RRNA_A_DIMETH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPYTDPSRVRGALNSIGVRPSKSMGQNFLIDPTPLKLALEHAEVNPNDVVVEVGPGLGV
CCCCCCHHHHHHHHHHCCCCCCHHHCCCEEECCCCHHEEEECCCCCCCCEEEEECCCCCH
LTWELLNAAGHVISIELDPRLAGRLRTEFAERPLTIVESDVLEIAPSAMLAAAGLPADTS
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHCCCCCCCC
YKLVANIPYAITSPLLRHFLEGDSPPSLMMVLMQWEVADRITAKPGDLSILAHSVQLYAT
CEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AEIIARVPAASFLPAPAVDSALVLMRRRATNAVPTAPKALFKVIRAGFSQARKKLINSLA
HHHHHHCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GGLAGQGFGKEQVLAAIVQAEIDPNLRAEVLTLEQWARLTETLGLATK
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNPYTDPSRVRGALNSIGVRPSKSMGQNFLIDPTPLKLALEHAEVNPNDVVVEVGPGLGV
CCCCCCHHHHHHHHHHCCCCCCHHHCCCEEECCCCHHEEEECCCCCCCCEEEEECCCCCH
LTWELLNAAGHVISIELDPRLAGRLRTEFAERPLTIVESDVLEIAPSAMLAAAGLPADTS
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHCCCCCCCC
YKLVANIPYAITSPLLRHFLEGDSPPSLMMVLMQWEVADRITAKPGDLSILAHSVQLYAT
CEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AEIIARVPAASFLPAPAVDSALVLMRRRATNAVPTAPKALFKVIRAGFSQARKKLINSLA
HHHHHHCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GGLAGQGFGKEQVLAAIVQAEIDPNLRAEVLTLEQWARLTETLGLATK
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA