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The map label for this gene is polX [H]

Identifier: 159900526

GI number: 159900526

Start: 5119846

End: 5121582

Strand: Direct

Name: polX [H]

Synonym: Haur_4013

Alternate gene names: 159900526

Gene position: 5119846-5121582 (Clockwise)

Preceding gene: 159900516

Following gene: 159900527

Centisome position: 80.67

GC content: 54.06

Gene sequence:

>1737_bases
ATGCTTAGCAACCAAGCAATTGCCCAAGTGTTTGCCGATATTGCCGATGCCTTGGAAGTGATCGGCGAAAATCGTTTTCG
ATTGGCGGCCTATCGTCGTGCCAGCGATACCCTCGCCGCCCAAACGACCAGCCTTGCCAGCCTGCGTGAGCAAGGGCTAT
TAACCAGTTTGCCCAATATTGGCGAGGCCAGCGCGGCAATTATTGGCGAATTGCTTGATCATGGCCATTCGGCCTTGGCC
GACCAGCTTTTGGAAAAAGTTCCGCCTGGGTTGTTGCAGATTTTGCGTGTGCCCGAAATCGGCCCCAAAACCGCAGCTCG
GCTTTTTCGCGATGAAGGCATTCAGGATCTTGAGGCCTTGTTTGCGGCGGCTCAGGATGGGCGTTTGGCCAAAATTAAAG
GCTTTGGCGCGAAAAGTGCAGCCAAAGTGTTGAGCGCTCTCGAAGCCATGCAAAATCAGGTGCTGCGCTTGCGGTTGGTC
GATGCCTTGCCCGTGGCCCAAGCATTAAGCGCCACGTTAGCTGAAATTGCCAGCATTAGCGCGGTGCAAGTGGTTGGTTC
AACCCGTCGTTATCAAGCCAGTGTTGGCGATTTGAATTTTGTGGTAGCTAGCTTAGATCAAGCTGCCGCCTATGCCGCGA
TCGCTGAATTACCTCAAGTTGCCCAAGCTACCCCCAGCGACAACGGCTTGCGCTTGTTGTTGCACAACGGCATGAATGCT
TGGATTGTAGCGGTTGCGCCCGAACATTGGGGCAGCGCTTTGGTCTATTGGACTGGCTCGACTAGCCATGTAGCTGGCTT
AAATCAATTGGCTCAGGCCCAGAATTGGCAGCTTGATCCGCTTAATTTTCCTGATTTTGCCGATGAAGCAGCGGTGTATG
CAGCTTTAGGCTTGGAATGGATCGCGCCTGAATTGCGCGAAGGCTGGGGCGAAATTGCGCTAGCTCAAGCCCAGCAATTG
CCCAAATTGCTCGAACAATCGGCGATTATCAGCGATGTACATTGGCACACGACGTGGAGTGATGGCAGTGCCAGCCTACG
CGAGATGGCGCTAGCCGGCATTGCCAAGGGTTATCGCTATATGGCGGTGGCTGATCATAGTGCCTATTTAGGCGTAACGG
GTGGGCTAGATGGCGAACGTTTGCTGGCTCAACGCGCCGAAATCAACGCACTCAATCAGCAATTAGCCGCCGAAGGCCAT
GAATTTCGCTTATTGCAAAGCTGCGAAGTCGATATTTTGCCCGATGGCAGCTTGGCCTTGCCCGATGAGGTGCTAGCCAC
ATTAGATTTAGTGGTGGCTTCGCCGCATGTGGCCTTACGCCAGCCCCGCGCTGAATCGACCGCCCGCATGCTGCGAGCGA
TTAACCATCCCTTGGTGACGATCATCGGACACCCAACTGGGCGGATTTTGAATGGCCGTGCTGGAGCCGATTATGATATG
GCGCAGATTATTGCGGCAGCAGCGGCAACGGGCACAGTTTTGGAAGTTAATGCTGGGCCTGAACGGCTTGATTTGGATGC
GCCAAATGTGCGGGCAGCGCTGGCGGCTGGGTGTAATATCAGCATCAACACCGATGCCCATGCCACGGCAGGTTTCGATA
ATCTGTTTTATGGAGTTGTAACGGCTCGCCGTGGTGGCGCTAGCAACCAGCAAGTAATCAACACATGGGATGCTGAGGCA
GTATTGGCGCTGCGTCAGCAAAAATTACAAAAACTTGGGCTTAGTAGCGAATCGTAG

Upstream 100 bases:

>100_bases
TTCGGCGAGAATATCCTCAGGCCAAGGTGAGCATGCTATAATCAAACCACGATCTACTCTACTACTCCTGCTCTTTTTTC
AGCGTGAGCACAGTCGAAGT

Downstream 100 bases:

>100_bases
TTTGGAGGCTGATCGCATGAATGATATATTCAGCAAGATTGTGCGTGGCGAATTGCCTTGCCATAAAGTGGCCGAAAATG
ACCAAACCCTAGCCTTTTTA

Product: phosphotransferase domain-containing protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MLSNQAIAQVFADIADALEVIGENRFRLAAYRRASDTLAAQTTSLASLREQGLLTSLPNIGEASAAIIGELLDHGHSALA
DQLLEKVPPGLLQILRVPEIGPKTAARLFRDEGIQDLEALFAAAQDGRLAKIKGFGAKSAAKVLSALEAMQNQVLRLRLV
DALPVAQALSATLAEIASISAVQVVGSTRRYQASVGDLNFVVASLDQAAAYAAIAELPQVAQATPSDNGLRLLLHNGMNA
WIVAVAPEHWGSALVYWTGSTSHVAGLNQLAQAQNWQLDPLNFPDFADEAAVYAALGLEWIAPELREGWGEIALAQAQQL
PKLLEQSAIISDVHWHTTWSDGSASLREMALAGIAKGYRYMAVADHSAYLGVTGGLDGERLLAQRAEINALNQQLAAEGH
EFRLLQSCEVDILPDGSLALPDEVLATLDLVVASPHVALRQPRAESTARMLRAINHPLVTIIGHPTGRILNGRAGADYDM
AQIIAAAAATGTVLEVNAGPERLDLDAPNVRAALAAGCNISINTDAHATAGFDNLFYGVVTARRGGASNQQVINTWDAEA
VLALRQQKLQKLGLSSES

Sequences:

>Translated_578_residues
MLSNQAIAQVFADIADALEVIGENRFRLAAYRRASDTLAAQTTSLASLREQGLLTSLPNIGEASAAIIGELLDHGHSALA
DQLLEKVPPGLLQILRVPEIGPKTAARLFRDEGIQDLEALFAAAQDGRLAKIKGFGAKSAAKVLSALEAMQNQVLRLRLV
DALPVAQALSATLAEIASISAVQVVGSTRRYQASVGDLNFVVASLDQAAAYAAIAELPQVAQATPSDNGLRLLLHNGMNA
WIVAVAPEHWGSALVYWTGSTSHVAGLNQLAQAQNWQLDPLNFPDFADEAAVYAALGLEWIAPELREGWGEIALAQAQQL
PKLLEQSAIISDVHWHTTWSDGSASLREMALAGIAKGYRYMAVADHSAYLGVTGGLDGERLLAQRAEINALNQQLAAEGH
EFRLLQSCEVDILPDGSLALPDEVLATLDLVVASPHVALRQPRAESTARMLRAINHPLVTIIGHPTGRILNGRAGADYDM
AQIIAAAAATGTVLEVNAGPERLDLDAPNVRAALAAGCNISINTDAHATAGFDNLFYGVVTARRGGASNQQVINTWDAEA
VLALRQQKLQKLGLSSES
>Mature_578_residues
MLSNQAIAQVFADIADALEVIGENRFRLAAYRRASDTLAAQTTSLASLREQGLLTSLPNIGEASAAIIGELLDHGHSALA
DQLLEKVPPGLLQILRVPEIGPKTAARLFRDEGIQDLEALFAAAQDGRLAKIKGFGAKSAAKVLSALEAMQNQVLRLRLV
DALPVAQALSATLAEIASISAVQVVGSTRRYQASVGDLNFVVASLDQAAAYAAIAELPQVAQATPSDNGLRLLLHNGMNA
WIVAVAPEHWGSALVYWTGSTSHVAGLNQLAQAQNWQLDPLNFPDFADEAAVYAALGLEWIAPELREGWGEIALAQAQQL
PKLLEQSAIISDVHWHTTWSDGSASLREMALAGIAKGYRYMAVADHSAYLGVTGGLDGERLLAQRAEINALNQQLAAEGH
EFRLLQSCEVDILPDGSLALPDEVLATLDLVVASPHVALRQPRAESTARMLRAINHPLVTIIGHPTGRILNGRAGADYDM
AQIIAAAAATGTVLEVNAGPERLDLDAPNVRAALAAGCNISINTDAHATAGFDNLFYGVVTARRGGASNQQVINTWDAEA
VLALRQQKLQKLGLSSES

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 61259; Mature: 61259

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNQAIAQVFADIADALEVIGENRFRLAAYRRASDTLAAQTTSLASLREQGLLTSLPNI
CCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCC
GEASAAIIGELLDHGHSALADQLLEKVPPGLLQILRVPEIGPKTAARLFRDEGIQDLEAL
CCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHH
FAAAQDGRLAKIKGFGAKSAAKVLSALEAMQNQVLRLRLVDALPVAQALSATLAEIASIS
HHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVQVVGSTRRYQASVGDLNFVVASLDQAAAYAAIAELPQVAQATPSDNGLRLLLHNGMNA
HHHHHCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
WIVAVAPEHWGSALVYWTGSTSHVAGLNQLAQAQNWQLDPLNFPDFADEAAVYAALGLEW
EEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
IAPELREGWGEIALAQAQQLPKLLEQSAIISDVHWHTTWSDGSASLREMALAGIAKGYRY
HCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCEE
MAVADHSAYLGVTGGLDGERLLAQRAEINALNQQLAAEGHEFRLLQSCEVDILPDGSLAL
EEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCCEEECCCCCCCC
PDEVLATLDLVVASPHVALRQPRAESTARMLRAINHPLVTIIGHPTGRILNGRAGADYDM
CHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCHHH
AQIIAAAAATGTVLEVNAGPERLDLDAPNVRAALAAGCNISINTDAHATAGFDNLFYGVV
HHHHHHHHCCCCEEEECCCCCEECCCCCCHHHHHHCCCEEEECCCCCCCCCHHHHHHHHH
TARRGGASNQQVINTWDAEAVLALRQQKLQKLGLSSES
HCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLSNQAIAQVFADIADALEVIGENRFRLAAYRRASDTLAAQTTSLASLREQGLLTSLPNI
CCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCC
GEASAAIIGELLDHGHSALADQLLEKVPPGLLQILRVPEIGPKTAARLFRDEGIQDLEAL
CCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHH
FAAAQDGRLAKIKGFGAKSAAKVLSALEAMQNQVLRLRLVDALPVAQALSATLAEIASIS
HHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVQVVGSTRRYQASVGDLNFVVASLDQAAAYAAIAELPQVAQATPSDNGLRLLLHNGMNA
HHHHHCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
WIVAVAPEHWGSALVYWTGSTSHVAGLNQLAQAQNWQLDPLNFPDFADEAAVYAALGLEW
EEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
IAPELREGWGEIALAQAQQLPKLLEQSAIISDVHWHTTWSDGSASLREMALAGIAKGYRY
HCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCEE
MAVADHSAYLGVTGGLDGERLLAQRAEINALNQQLAAEGHEFRLLQSCEVDILPDGSLAL
EEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCCEEECCCCCCCC
PDEVLATLDLVVASPHVALRQPRAESTARMLRAINHPLVTIIGHPTGRILNGRAGADYDM
CHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCHHH
AQIIAAAAATGTVLEVNAGPERLDLDAPNVRAALAAGCNISINTDAHATAGFDNLFYGVV
HHHHHHHHCCCCEEEECCCCCEECCCCCCHHHHHHCCCEEEECCCCCCCCCHHHHHHHHH
TARRGGASNQQVINTWDAEAVLALRQQKLQKLGLSSES
HCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]