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The map label for this gene is pyrR

Identifier: 159900503

GI number: 159900503

Start: 5089084

End: 5089620

Strand: Direct

Name: pyrR

Synonym: Haur_3990

Alternate gene names: 159900503

Gene position: 5089084-5089620 (Clockwise)

Preceding gene: 159900502

Following gene: 159900504

Centisome position: 80.19

GC content: 54.19

Gene sequence:

>537_bases
ATGACACCCAAACAGTTGATGAATGACGAGGAAATTCGCCGCGCCCTCAAACGTATCGCCCATGAGATCGTTGAGCGCAA
CGCTGGAGCTAATTTGGTTTCGCTGGTGGGGATTCATCGGCGGGGTGTGCCCTTGGCTCGCCGCTTAGCCGCGATGATCG
CCGAAACCGAGCATGTGCAGGTGCCAGTTGGCGAGCTTGATATCGGCCTCTATCGCGACGATTTACATTCGCGTGGGCCA
GCCCCAATCTTGGGCCGCACAATTTTGCCCGAATTAGGCAAACGGGTGGTAGTGTTGGTCGATGATGTGCTCTACACTGG
CCGCACCATTCGCGCAGCATTAAATGAGTTGAGCGATTGGGGTCGCCCAAGTGCCATCCAATTGGCCGTACTGGTCGATC
GCGGTCATCGCGAGTTGCCAATTCGCGCCGATTTTGTCGGCAAAAATATTCCAACCGCCAAAAATGAGCGGGTTGATGTC
CAACTCAGTGAAATTGATGCAGCCCAAGATAGTGTTGTAATTGTGCAGGAGGACTGA

Upstream 100 bases:

>100_bases
GCTAAATCATTCATTAGCCCTAGGTCGCTGTGTGGTAGCGCCGCCAGCCAATCGGGGCTACAATAGACAATACGCTATTG
CTGGCAGGAGCAAAGATCCT

Downstream 100 bases:

>100_bases
TGGGGCGAAGCGGGCAAGCACGACGACGGCGACGGACATCACGCTTTTTGGAGCAAGTTGGGTCACGGCGCAAACGAGCA
GCGGTGGCACCATTGCAACT

Product: Uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MTPKQLMNDEEIRRALKRIAHEIVERNAGANLVSLVGIHRRGVPLARRLAAMIAETEHVQVPVGELDIGLYRDDLHSRGP
APILGRTILPELGKRVVVLVDDVLYTGRTIRAALNELSDWGRPSAIQLAVLVDRGHRELPIRADFVGKNIPTAKNERVDV
QLSEIDAAQDSVVIVQED

Sequences:

>Translated_178_residues
MTPKQLMNDEEIRRALKRIAHEIVERNAGANLVSLVGIHRRGVPLARRLAAMIAETEHVQVPVGELDIGLYRDDLHSRGP
APILGRTILPELGKRVVVLVDDVLYTGRTIRAALNELSDWGRPSAIQLAVLVDRGHRELPIRADFVGKNIPTAKNERVDV
QLSEIDAAQDSVVIVQED
>Mature_177_residues
TPKQLMNDEEIRRALKRIAHEIVERNAGANLVSLVGIHRRGVPLARRLAAMIAETEHVQVPVGELDIGLYRDDLHSRGPA
PILGRTILPELGKRVVVLVDDVLYTGRTIRAALNELSDWGRPSAIQLAVLVDRGHRELPIRADFVGKNIPTAKNERVDVQ
LSEIDAAQDSVVIVQED

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_HERA2 (A9AVM2)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001546750.1
- ProteinModelPortal:   A9AVM2
- SMR:   A9AVM2
- GeneID:   5735851
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3990
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- BioCyc:   HAUR316274:HAUR_3990-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 19720; Mature: 19589

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPKQLMNDEEIRRALKRIAHEIVERNAGANLVSLVGIHRRGVPLARRLAAMIAETEHVQ
CCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEE
VPVGELDIGLYRDDLHSRGPAPILGRTILPELGKRVVVLVDDVLYTGRTIRAALNELSDW
CCCCCCCCCEEHHHHHCCCCCCHHHHHHHHHCCCEEEEEEHHHHHCCHHHHHHHHHHHHC
GRPSAIQLAVLVDRGHRELPIRADFVGKNIPTAKNERVDVQLSEIDAAQDSVVIVQED
CCCCCEEEEEEEECCCCCCCEEHHCCCCCCCCCCCCEEEEEHHHCCCCCCCEEEEECC
>Mature Secondary Structure 
TPKQLMNDEEIRRALKRIAHEIVERNAGANLVSLVGIHRRGVPLARRLAAMIAETEHVQ
CCHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEE
VPVGELDIGLYRDDLHSRGPAPILGRTILPELGKRVVVLVDDVLYTGRTIRAALNELSDW
CCCCCCCCCEEHHHHHCCCCCCHHHHHHHHHCCCEEEEEEHHHHHCCHHHHHHHHHHHHC
GRPSAIQLAVLVDRGHRELPIRADFVGKNIPTAKNERVDVQLSEIDAAQDSVVIVQED
CCCCCEEEEEEEECCCCCCCEEHHCCCCCCCCCCCCEEEEEHHHCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA