Click here to switch to the map view.

The map label for this gene is lgrD [H]

Identifier: 159900485

GI number: 159900485

Start: 5050094

End: 5053474

Strand: Direct

Name: lgrD [H]

Synonym: Haur_3972

Alternate gene names: 159900485

Gene position: 5050094-5053474 (Clockwise)

Preceding gene: 159900484

Following gene: 159900486

Centisome position: 79.57

GC content: 65.28

Gene sequence:

>3381_bases
ATGTACACAAAAGAAGAACTCTTGAAGCGGCGCGCCCAGCTTTCGGCCAATCAGCGCACGATGCTGGACAAGCAACTCCG
TGGGGAAGCGATGCTCCAGGCCGATCCAGGCTACGCCGCGATCGGCAAACGGCCGGCCGATGCGCCGACGCCGCTGTCTT
TTTCCCAGGAGCGCCTCTGGTTTTTGCAGCAGCTTGACCCCGCCAACGCCGCGTTCAATGGCCTGCGGCCCATGATGATC
GCCGGTCCGCTGGACATCGATCTGATCAACCGTGTCGCCAGGGAGATGTACCGGCGCCACGAGATCCTGCGCACCAGCTT
CCGCTTGATCGATGGTGCTCCATGCCAGATCGTGGACCAGGATCTGCCCCGCACCTACGCCGTGCCGGTCATCGATCTGG
GCCACCTGCCGCCCGGCGACGCCGAGGCCGAGGCACGCCGGCTGATGGCCGAGGAGGCGCGCACGCCGTTTGACATGGGC
CAGGCACCGATGATGCGTCTCACTCTGATCAGCCTGGACGCCGCCGAGCATGCGCTGCTGCTGAGCCTTCACCATATCGC
CTATGATGAATGGTCTAATCAGGTGCTGGTCGATGAGTTCTCCGTGTTGTATCGGGCCTTCGCCCAGGGCCAACCCTCGC
CCTTGCCCGAGCTGCCGATCCAGTACGGCGATTACGCCTACTGGCAGCGCGAGTGGTTGCAGGGATCGGTGCTGGAAGCC
CAGCTCGCCTACTGGGCCGAGCAGCTCGGCGGCGCGCTGCCGACCCTGGATCTGCCGACCGACCATCCCCGGCCTGCGGT
CCAGAACTTCCGCCTCCGTACCGAGCAGACCCTTCTGCCCGCCGAGCTGGCCGCCGCCCTGCGGGCGATGAGCCAGAAGG
AAGGCGTGACCCTGTTTATGGCCCTGCTAAGTGCCTTCAAAACCCTGCTTTTTTACTATACAAATCAACCTGAGAGCATT
GTCGGCACCTTTATCGCCGGGCGGAGCCGGCCGGAACTTGAGCGACTGATCGGCTTTTTTGTTAATTCGCTGCCGCTGCG
CAGCGACCTTACCGGCGATCCCACCTTCTCCGAGGTGCTCAAGCAGGTGCGCGCGGTGACCCTGGGCGCCTACAACCACC
AGGATGTGCCTATCGAGAAGCTGATCGAGACCTTCACGCCCAAGCGTGACCTCAGCCGAACGGCTATCTACCAGGCGATG
TTTGTCTTGCAGAACGTTCCCAAGCCCGGTGATGCCGCCGAGCCGTCGGCCCTAGTGATCCGCGAGTGGCAGGATGCCGA
CGCTTCGGCCGGCGCCGACCTCCAATGCGACATTACCCTGATGGTCTACGAGTTGCCGGATGGCGGCCTGCGCTGCCAGT
TCGAGTACGACTCGTCACTGTTCGAGGCGGCGACGATCCAACGCATGCTCGCTCAATTCGAGACTCTGCTCGCGGCGGTC
TCCAGCAACCCCGGCCAGCGCCTCTCGCGTTTGTCCTTGCTGACCGACCAAGAGCGCCAGCAGGTGCTCTATGACTGGAA
TGCCACTGCGGTGCCGTTCGCCGTGGACAGCTGCATCCATACGCTGTTCGAGTCCCAGGCGGCCAGAGCACCCCAGGCCA
TCGCCCTAGTGCATGGCAAGGAGCGTCTGACCTACGGCGAGCTTAACCGGCGGGCCAACCAGCTGTCCCACTACCTGCGC
ACGAGCGGAGTGGGCTCCGGGGGTTTTGTCGGGCTGGCCCTGGAGCGATCGGTGGAAATGGTGGTCGCGGTGTTGGGGGT
GCTCAAGGCCGGCGCCGCCTATGTCCCACTCGACCCGACCTATCCGGCGGCGCGCCTCCAGTTTATGCTCGCGGACGCCG
ACGTCGGCTTCGTGCTGACCACGGGGCGCCTGCGTGATCGTCTGGCCGGCACGGACCGCACGCTCCTGGAGTGGGAAGCG
CTCGGAAACCTGGACGCGTATCCGCCCGACGATCCGCCGGCTCGCGCAACTGCCGCAAGCCCGGCCTATGTGATCTACAC
CTCGGGATCAACTGGCCAGCCCAAAGGAGTGGTCGTGCCCCACGGCGCGCTCGTCCAGACCTACCACACCTGGGAGTCAG
CCTACGGCTTGGATGGCGCCGTGCGCTGTCATTTGCAGATGGCAGCGTTCTCCTTCGATGTCTGCGCCGGCGATCTTATC
CGCGCGCTCGGCTCCGGGGGCACTCTCGTGATCTGCCCGCGCGACACGCTGCTCGCCCCCGCCGACCTGCACGCGCTGAT
CGTCGCCGAGGGCGTGGACTGCGCCGAATTCGTGCCGGCGGTGTTGCGCGAGCTCGTCGCCTACCTGGAAGGCTCCGGCG
GCGACCTGGGCTCTATGCGCCTGCTGATCGCCGGTTCGGATACCTGGTACGGCGAAGAGTATGCCCGGGTCGCCCGCCTC
TGCGGCCCTGACACCCGCCTGGTCAATTCCTACGGCGTCACCGAGGCCGTGATCGACAGCACCTACTTCGAGGCCGGCGC
GGCTGCCGAACTGCCCGCCAGACGCCAGGTGCCGATCGGCCGGCCATTCGCGGCGACCCGGGCGTATGTGCTCAATCGGC
TCGGTCAGCCGCAGCCGATCGGCGTGCCCGGCGAACTCTATCTCGGCGGCTCGCGGCTGGCGCTGGGCTACTGGCGGCGC
CCCGGATTAACCGCCGAGCGTTTTGTTCCCGATCCCTTCGCCGGGGAACCAGGCGCACGGATGTACCGCACCGGCGATGC
CGCCCGCTTCCGCGCCGACGGCACGATCGAGTTTCTCGGTCGGATCGACCAGCAGGTCAAGTTGCACGGTGTCCGCATCG
AACTGGGCGAGATCGAGGCCATCCTGCTCCAGCAGCCCGGCGTCATCCAGGCCGCCGCCGCCATCCGCGAAAATCAACTC
GGCCACCCCATCCTGGTAGCCTACCTTGTGACCGACGCGCTAGGCGATGAAGCGGCCTTGCGGGCGGCTCTGCGCGAACG
GCTGCCCGAGCATATGGTCCCTGCGGCGACTATCATCCTCCCGTCCCTGCCGCTAACTCCCAACGGCAAGATCGACCGCC
AAGCCCTGCCAGAGCCTGACCTTGGCAGATCGGAGATGAGCGCCGCCTACGAGGCGCCTGGGAGCCTGATCGAGGAAACG
CTGGCCGAGATCTGGGGCGAAGTCCTCAAGCGCGAACAGGTCGGCATTCGCGATAACTTCTTCGAGCTTGGCGGCCACTC
GTTGCTGATCACCCAGGTGATCTACCGGGCCAATGAGGCGTTTGAGCTTAATCTACCCCTACGCAGCCTTTTTGAGGAGC
CGACGATCGCGGATTTCGCCCTGAGGGTCGAGGAAGCGCTCCTCGACAAACTTGAGCAACTCGACGATGAGGAAGCCCAG
CAGCTGATCGAGGGGTTGTAG

Upstream 100 bases:

>100_bases
CCGGGGCGTGGTTATTTGTCGGACGCATGTTTCTCAATCTGGCTGACGGGCAGGCGCTTGGCTTCGCGGGCGCGTCTGCC
CCGCCCATCGAAGGATTACC

Downstream 100 bases:

>100_bases
CAGCAATCGGGTGTCACTAGGAGCCAGTTAGTTCTCTCAGTAGGAGTGTTAAATGTTGGGACTCAATTCTTCCTTGCCAT
TGCCCGAAGGGCAACCGGAC

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1126; Mature: 1126

Protein sequence:

>1126_residues
MYTKEELLKRRAQLSANQRTMLDKQLRGEAMLQADPGYAAIGKRPADAPTPLSFSQERLWFLQQLDPANAAFNGLRPMMI
AGPLDIDLINRVAREMYRRHEILRTSFRLIDGAPCQIVDQDLPRTYAVPVIDLGHLPPGDAEAEARRLMAEEARTPFDMG
QAPMMRLTLISLDAAEHALLLSLHHIAYDEWSNQVLVDEFSVLYRAFAQGQPSPLPELPIQYGDYAYWQREWLQGSVLEA
QLAYWAEQLGGALPTLDLPTDHPRPAVQNFRLRTEQTLLPAELAAALRAMSQKEGVTLFMALLSAFKTLLFYYTNQPESI
VGTFIAGRSRPELERLIGFFVNSLPLRSDLTGDPTFSEVLKQVRAVTLGAYNHQDVPIEKLIETFTPKRDLSRTAIYQAM
FVLQNVPKPGDAAEPSALVIREWQDADASAGADLQCDITLMVYELPDGGLRCQFEYDSSLFEAATIQRMLAQFETLLAAV
SSNPGQRLSRLSLLTDQERQQVLYDWNATAVPFAVDSCIHTLFESQAARAPQAIALVHGKERLTYGELNRRANQLSHYLR
TSGVGSGGFVGLALERSVEMVVAVLGVLKAGAAYVPLDPTYPAARLQFMLADADVGFVLTTGRLRDRLAGTDRTLLEWEA
LGNLDAYPPDDPPARATAASPAYVIYTSGSTGQPKGVVVPHGALVQTYHTWESAYGLDGAVRCHLQMAAFSFDVCAGDLI
RALGSGGTLVICPRDTLLAPADLHALIVAEGVDCAEFVPAVLRELVAYLEGSGGDLGSMRLLIAGSDTWYGEEYARVARL
CGPDTRLVNSYGVTEAVIDSTYFEAGAAAELPARRQVPIGRPFAATRAYVLNRLGQPQPIGVPGELYLGGSRLALGYWRR
PGLTAERFVPDPFAGEPGARMYRTGDAARFRADGTIEFLGRIDQQVKLHGVRIELGEIEAILLQQPGVIQAAAAIRENQL
GHPILVAYLVTDALGDEAALRAALRERLPEHMVPAATIILPSLPLTPNGKIDRQALPEPDLGRSEMSAAYEAPGSLIEET
LAEIWGEVLKREQVGIRDNFFELGGHSLLITQVIYRANEAFELNLPLRSLFEEPTIADFALRVEEALLDKLEQLDDEEAQ
QLIEGL

Sequences:

>Translated_1126_residues
MYTKEELLKRRAQLSANQRTMLDKQLRGEAMLQADPGYAAIGKRPADAPTPLSFSQERLWFLQQLDPANAAFNGLRPMMI
AGPLDIDLINRVAREMYRRHEILRTSFRLIDGAPCQIVDQDLPRTYAVPVIDLGHLPPGDAEAEARRLMAEEARTPFDMG
QAPMMRLTLISLDAAEHALLLSLHHIAYDEWSNQVLVDEFSVLYRAFAQGQPSPLPELPIQYGDYAYWQREWLQGSVLEA
QLAYWAEQLGGALPTLDLPTDHPRPAVQNFRLRTEQTLLPAELAAALRAMSQKEGVTLFMALLSAFKTLLFYYTNQPESI
VGTFIAGRSRPELERLIGFFVNSLPLRSDLTGDPTFSEVLKQVRAVTLGAYNHQDVPIEKLIETFTPKRDLSRTAIYQAM
FVLQNVPKPGDAAEPSALVIREWQDADASAGADLQCDITLMVYELPDGGLRCQFEYDSSLFEAATIQRMLAQFETLLAAV
SSNPGQRLSRLSLLTDQERQQVLYDWNATAVPFAVDSCIHTLFESQAARAPQAIALVHGKERLTYGELNRRANQLSHYLR
TSGVGSGGFVGLALERSVEMVVAVLGVLKAGAAYVPLDPTYPAARLQFMLADADVGFVLTTGRLRDRLAGTDRTLLEWEA
LGNLDAYPPDDPPARATAASPAYVIYTSGSTGQPKGVVVPHGALVQTYHTWESAYGLDGAVRCHLQMAAFSFDVCAGDLI
RALGSGGTLVICPRDTLLAPADLHALIVAEGVDCAEFVPAVLRELVAYLEGSGGDLGSMRLLIAGSDTWYGEEYARVARL
CGPDTRLVNSYGVTEAVIDSTYFEAGAAAELPARRQVPIGRPFAATRAYVLNRLGQPQPIGVPGELYLGGSRLALGYWRR
PGLTAERFVPDPFAGEPGARMYRTGDAARFRADGTIEFLGRIDQQVKLHGVRIELGEIEAILLQQPGVIQAAAAIRENQL
GHPILVAYLVTDALGDEAALRAALRERLPEHMVPAATIILPSLPLTPNGKIDRQALPEPDLGRSEMSAAYEAPGSLIEET
LAEIWGEVLKREQVGIRDNFFELGGHSLLITQVIYRANEAFELNLPLRSLFEEPTIADFALRVEEALLDKLEQLDDEEAQ
QLIEGL
>Mature_1126_residues
MYTKEELLKRRAQLSANQRTMLDKQLRGEAMLQADPGYAAIGKRPADAPTPLSFSQERLWFLQQLDPANAAFNGLRPMMI
AGPLDIDLINRVAREMYRRHEILRTSFRLIDGAPCQIVDQDLPRTYAVPVIDLGHLPPGDAEAEARRLMAEEARTPFDMG
QAPMMRLTLISLDAAEHALLLSLHHIAYDEWSNQVLVDEFSVLYRAFAQGQPSPLPELPIQYGDYAYWQREWLQGSVLEA
QLAYWAEQLGGALPTLDLPTDHPRPAVQNFRLRTEQTLLPAELAAALRAMSQKEGVTLFMALLSAFKTLLFYYTNQPESI
VGTFIAGRSRPELERLIGFFVNSLPLRSDLTGDPTFSEVLKQVRAVTLGAYNHQDVPIEKLIETFTPKRDLSRTAIYQAM
FVLQNVPKPGDAAEPSALVIREWQDADASAGADLQCDITLMVYELPDGGLRCQFEYDSSLFEAATIQRMLAQFETLLAAV
SSNPGQRLSRLSLLTDQERQQVLYDWNATAVPFAVDSCIHTLFESQAARAPQAIALVHGKERLTYGELNRRANQLSHYLR
TSGVGSGGFVGLALERSVEMVVAVLGVLKAGAAYVPLDPTYPAARLQFMLADADVGFVLTTGRLRDRLAGTDRTLLEWEA
LGNLDAYPPDDPPARATAASPAYVIYTSGSTGQPKGVVVPHGALVQTYHTWESAYGLDGAVRCHLQMAAFSFDVCAGDLI
RALGSGGTLVICPRDTLLAPADLHALIVAEGVDCAEFVPAVLRELVAYLEGSGGDLGSMRLLIAGSDTWYGEEYARVARL
CGPDTRLVNSYGVTEAVIDSTYFEAGAAAELPARRQVPIGRPFAATRAYVLNRLGQPQPIGVPGELYLGGSRLALGYWRR
PGLTAERFVPDPFAGEPGARMYRTGDAARFRADGTIEFLGRIDQQVKLHGVRIELGEIEAILLQQPGVIQAAAAIRENQL
GHPILVAYLVTDALGDEAALRAALRERLPEHMVPAATIILPSLPLTPNGKIDRQALPEPDLGRSEMSAAYEAPGSLIEET
LAEIWGEVLKREQVGIRDNFFELGGHSLLITQVIYRANEAFELNLPLRSLFEEPTIADFALRVEEALLDKLEQLDDEEAQ
QLIEGL

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=579, Percent_Identity=25.3886010362694, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI156151445, Length=557, Percent_Identity=22.0825852782765, Blast_Score=87, Evalue=6e-17,
Organism=Escherichia coli, GI1786801, Length=1054, Percent_Identity=29.8861480075901, Blast_Score=296, Evalue=7e-81,
Organism=Escherichia coli, GI1786810, Length=515, Percent_Identity=27.7669902912621, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI145693145, Length=530, Percent_Identity=26.0377358490566, Blast_Score=101, Evalue=3e-22,
Organism=Escherichia coli, GI1788107, Length=564, Percent_Identity=23.0496453900709, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI221142682, Length=506, Percent_Identity=23.3201581027668, Blast_Score=93, Evalue=9e-20,
Organism=Escherichia coli, GI1790505, Length=550, Percent_Identity=23.0909090909091, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=1080, Percent_Identity=21.4814814814815, Blast_Score=128, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17556356, Length=583, Percent_Identity=24.8713550600343, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI32563687, Length=520, Percent_Identity=22.8846153846154, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32564422, Length=581, Percent_Identity=22.7194492254733, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32564420, Length=581, Percent_Identity=22.7194492254733, Blast_Score=82, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=747, Percent_Identity=27.041499330656, Blast_Score=238, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24648676, Length=608, Percent_Identity=30.4276315789474, Blast_Score=202, Evalue=8e-52,
Organism=Drosophila melanogaster, GI24581924, Length=541, Percent_Identity=24.0295748613678, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667955, Length=386, Percent_Identity=26.1658031088083, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667959, Length=386, Percent_Identity=26.1658031088083, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62472339, Length=386, Percent_Identity=26.1658031088083, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648260, Length=541, Percent_Identity=21.2569316081331, Blast_Score=72, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 123726; Mature: 123726

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTKEELLKRRAQLSANQRTMLDKQLRGEAMLQADPGYAAIGKRPADAPTPLSFSQERLW
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHH
FLQQLDPANAAFNGLRPMMIAGPLDIDLINRVAREMYRRHEILRTSFRLIDGAPCQIVDQ
HHHHCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
DLPRTYAVPVIDLGHLPPGDAEAEARRLMAEEARTPFDMGQAPMMRLTLISLDAAEHALL
CCCCEEECCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHH
LSLHHIAYDEWSNQVLVDEFSVLYRAFAQGQPSPLPELPIQYGDYAYWQREWLQGSVLEA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHH
QLAYWAEQLGGALPTLDLPTDHPRPAVQNFRLRTEQTLLPAELAAALRAMSQKEGVTLFM
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHH
ALLSAFKTLLFYYTNQPESIVGTFIAGRSRPELERLIGFFVNSLPLRSDLTGDPTFSEVL
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
KQVRAVTLGAYNHQDVPIEKLIETFTPKRDLSRTAIYQAMFVLQNVPKPGDAAEPSALVI
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
REWQDADASAGADLQCDITLMVYELPDGGLRCQFEYDSSLFEAATIQRMLAQFETLLAAV
EECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
SSNPGQRLSRLSLLTDQERQQVLYDWNATAVPFAVDSCIHTLFESQAARAPQAIALVHGK
CCCHHHHHHHHHHHCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
ERLTYGELNRRANQLSHYLRTSGVGSGGFVGLALERSVEMVVAVLGVLKAGAAYVPLDPT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEECCCCC
YPAARLQFMLADADVGFVLTTGRLRDRLAGTDRTLLEWEALGNLDAYPPDDPPARATAAS
CCHHHEEEEEECCCCCEEEECHHHHHHHCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCCC
PAYVIYTSGSTGQPKGVVVPHGALVQTYHTWESAYGLDGAVRCHLQMAAFSFDVCAGDLI
CEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHH
RALGSGGTLVICPRDTLLAPADLHALIVAEGVDCAEFVPAVLRELVAYLEGSGGDLGSMR
HHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEE
LLIAGSDTWYGEEYARVARLCGPDTRLVNSYGVTEAVIDSTYFEAGAAAELPARRQVPIG
EEEECCCCCCCHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
RPFAATRAYVLNRLGQPQPIGVPGELYLGGSRLALGYWRRPGLTAERFVPDPFAGEPGAR
CCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECCCCCCCHHHCCCCCCCCCCCCC
MYRTGDAARFRADGTIEFLGRIDQQVKLHGVRIELGEIEAILLQQPGVIQAAAAIRENQL
EEECCCCCEEECCCHHHHHHHHCHHEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCC
GHPILVAYLVTDALGDEAALRAALRERLPEHMVPAATIILPSLPLTPNGKIDRQALPEPD
CCHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHCCHHHHEECCCCCCCCCCCCCCCCCCCC
LGRSEMSAAYEAPGSLIEETLAEIWGEVLKREQVGIRDNFFELGGHSLLITQVIYRANEA
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHCCCC
FELNLPLRSLFEEPTIADFALRVEEALLDKLEQLDDEEAQQLIEGL
EEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MYTKEELLKRRAQLSANQRTMLDKQLRGEAMLQADPGYAAIGKRPADAPTPLSFSQERLW
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHH
FLQQLDPANAAFNGLRPMMIAGPLDIDLINRVAREMYRRHEILRTSFRLIDGAPCQIVDQ
HHHHCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
DLPRTYAVPVIDLGHLPPGDAEAEARRLMAEEARTPFDMGQAPMMRLTLISLDAAEHALL
CCCCEEECCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHH
LSLHHIAYDEWSNQVLVDEFSVLYRAFAQGQPSPLPELPIQYGDYAYWQREWLQGSVLEA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHH
QLAYWAEQLGGALPTLDLPTDHPRPAVQNFRLRTEQTLLPAELAAALRAMSQKEGVTLFM
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHH
ALLSAFKTLLFYYTNQPESIVGTFIAGRSRPELERLIGFFVNSLPLRSDLTGDPTFSEVL
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
KQVRAVTLGAYNHQDVPIEKLIETFTPKRDLSRTAIYQAMFVLQNVPKPGDAAEPSALVI
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
REWQDADASAGADLQCDITLMVYELPDGGLRCQFEYDSSLFEAATIQRMLAQFETLLAAV
EECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
SSNPGQRLSRLSLLTDQERQQVLYDWNATAVPFAVDSCIHTLFESQAARAPQAIALVHGK
CCCHHHHHHHHHHHCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
ERLTYGELNRRANQLSHYLRTSGVGSGGFVGLALERSVEMVVAVLGVLKAGAAYVPLDPT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEECCCCC
YPAARLQFMLADADVGFVLTTGRLRDRLAGTDRTLLEWEALGNLDAYPPDDPPARATAAS
CCHHHEEEEEECCCCCEEEECHHHHHHHCCCCCCEEEHHHCCCCCCCCCCCCCCCCCCCC
PAYVIYTSGSTGQPKGVVVPHGALVQTYHTWESAYGLDGAVRCHLQMAAFSFDVCAGDLI
CEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHH
RALGSGGTLVICPRDTLLAPADLHALIVAEGVDCAEFVPAVLRELVAYLEGSGGDLGSMR
HHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEE
LLIAGSDTWYGEEYARVARLCGPDTRLVNSYGVTEAVIDSTYFEAGAAAELPARRQVPIG
EEEECCCCCCCHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
RPFAATRAYVLNRLGQPQPIGVPGELYLGGSRLALGYWRRPGLTAERFVPDPFAGEPGAR
CCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECCCCCCCHHHCCCCCCCCCCCCC
MYRTGDAARFRADGTIEFLGRIDQQVKLHGVRIELGEIEAILLQQPGVIQAAAAIRENQL
EEECCCCCEEECCCHHHHHHHHCHHEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHCCC
GHPILVAYLVTDALGDEAALRAALRERLPEHMVPAATIILPSLPLTPNGKIDRQALPEPD
CCHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHCCHHHHEECCCCCCCCCCCCCCCCCCCC
LGRSEMSAAYEAPGSLIEETLAEIWGEVLKREQVGIRDNFFELGGHSLLITQVIYRANEA
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHCCCC
FELNLPLRSLFEEPTIADFALRVEEALLDKLEQLDDEEAQQLIEGL
EEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA