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The map label for this gene is glmS [H]

Identifier: 159900463

GI number: 159900463

Start: 4951524

End: 4953368

Strand: Direct

Name: glmS [H]

Synonym: Haur_3948

Alternate gene names: 159900463

Gene position: 4951524-4953368 (Clockwise)

Preceding gene: 159900455

Following gene: 159900464

Centisome position: 78.02

GC content: 50.62

Gene sequence:

>1845_bases
ATGTGCGGAATTGTTGGATATGTTGGCCCACGCGAAGCAACCGATGTGATTGTGCGGGGCTTAGAGTTATTAGAATATCG
CGGCTACGATTCAGCGGGCATCGCCATTTTAGAGGATGCCGAATTTCAAATGCGCCGCTCGGTTGGCAAGCTGGTTAATT
TGCGCCGCCGTTTGCATGCCGAGCCAACCGCTGGTCATCAAGGCATCGGCCACACCCGTTGGGCCACGCACGGCGCAGTC
ACCGAAGCCAATGCCCACCCCCATCGCGATAATAGTGGCCGCATCGTGGTGATTCAAAATGGGATTGTTGAGAATTATCT
CGAAATTAAAGGTCGGTTGATTGAACAAGGTGTTCGCTTTCATTCGCAAACCGATACCGAAGTCATTGCCCAAATGCTTG
GGTTATATACCGCCGAATATGGCGATTTTCAACGCGCTTTCGGCCAAGTGATGAGTGAATTACGTGGTGGTAATGCAGTT
GTAGCTATGGATCAAACCCAGCCTGATTTGATTTTAGCGGCCCGAATTGGCAATGCTGGGGCAGTGGTAATTGGCCATGG
TGATACTGAAAATTTCGTCGCCTCCGATTTGCCAGCAATTGTCGATTACACCCAACATATGGTCTTCCTCGAAGATGGCG
AGATGGCGATCGTGCGATCAACCGGCGTGGAATATGTCAAGCTCGATGGCACGCCAATCAGCAAAACGCCTACCACCGTT
GCATGGGACCCCGTATCGGCGGCCAAAGGTGGTTACAAACACTTTATGCATAAAGAGATTTTCGAGCAACCACGCACAAC
AACCGACACATTGCGCGGACGAGTCGATCTCGAAGCCGGACGAATCGAGCTTGATGGACTGACGTTGAGCGATGCCGAAA
TGCAAAAGCTCGATTGCATCTATGCAGTAGCCTGTGGTACTGCTTGGCATGCCTGTTTGATCAATAAATATTTTATCGAA
ACCTTGGCCCGTGTACGAGTTGAAGTCGATTATGGCTCCGAATTCCGCTATCGTAATCCTGTGATGAACGAACGCAGTTT
ATTGCTGGCCTTGACCCAATCGGGTGAAACCGTCGATACCTTGGCAGCAATGGCTGAAGCCCGCGAACAAGGCGTAAAAA
GTGTGGCAATTTTGAATGCGATTGGTTCGCAAGCAGGCCGCTTGGCTGATGGTGGCGCAATCTACATTCACTCAGGCCCA
GAAATTTCAGTGGCTTCAACCAAAGTCTTCACTGGTATGTTGATGGCAGGCTATCTGTTTGCGCTGCGCTTGGCACAAGC
TCGTGGCACGCTCACCAGCGCCGAAATTCGCGAACACATCCAAGCGTTAATCGAAATTCCCGCCAAAATCGACACTATGC
TCAAAGATACCGCCATTTATGATCAACTGGCGGATCTGTATCATCACTCAACCGATATGCTCTACCTTGGGCGCTGGGTC
AATGCCCCGATTGCGCTCGAAGGTGCGCTCAAGATGAAGGAAATTAGCTATATTCACGCCGAGGGCTACCCCGCAGGCGA
AATGAAGCATGGCCCGATTGCCTTGATCGATGAACGAATGCCAGTGATTTGTATTGCGACCAAAGATCATGTCTATGAAA
AGATGCTCTCGAATGTTGAGCAAGTCATCGCACGAGGTGGTAAAGTGATTGCCTTGGTCAATCCCAGCGATGAACTTGTG
CGCTCCAAGGCTGATCATGTGATCGAAGTGCCTGAAACTACACCGTTATTGGCAGCAGTGTTGAATGTTGTGCCGATGCA
ACTCTTCTCGTATGCCATGGCCGTGCGGCGTGGTGCTGATGTTGATCAGCCGCGTAACTTGGCCAAATCAGTCACTGTCG
AATAG

Upstream 100 bases:

>100_bases
AGCAGCATGCCCCGCCCCCGTTCAGCGACGATACGGGTTGGTGCGGTGTGGTGCTATGTTGTGTTTTAGCGAGCTTTTAT
CAACGTGGAGTATAGATTTT

Downstream 100 bases:

>100_bases
TGTCCTTCAGCAAACCTCCGCTCTTCTTGTGGAATGGGAATAAAGTTGGGAACTCGAAAATAAAGTTGGATACTACGAAA
ATAAAGTTGGAAACTCGAAA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MCGIVGYVGPREATDVIVRGLELLEYRGYDSAGIAILEDAEFQMRRSVGKLVNLRRRLHAEPTAGHQGIGHTRWATHGAV
TEANAHPHRDNSGRIVVIQNGIVENYLEIKGRLIEQGVRFHSQTDTEVIAQMLGLYTAEYGDFQRAFGQVMSELRGGNAV
VAMDQTQPDLILAARIGNAGAVVIGHGDTENFVASDLPAIVDYTQHMVFLEDGEMAIVRSTGVEYVKLDGTPISKTPTTV
AWDPVSAAKGGYKHFMHKEIFEQPRTTTDTLRGRVDLEAGRIELDGLTLSDAEMQKLDCIYAVACGTAWHACLINKYFIE
TLARVRVEVDYGSEFRYRNPVMNERSLLLALTQSGETVDTLAAMAEAREQGVKSVAILNAIGSQAGRLADGGAIYIHSGP
EISVASTKVFTGMLMAGYLFALRLAQARGTLTSAEIREHIQALIEIPAKIDTMLKDTAIYDQLADLYHHSTDMLYLGRWV
NAPIALEGALKMKEISYIHAEGYPAGEMKHGPIALIDERMPVICIATKDHVYEKMLSNVEQVIARGGKVIALVNPSDELV
RSKADHVIEVPETTPLLAAVLNVVPMQLFSYAMAVRRGADVDQPRNLAKSVTVE

Sequences:

>Translated_614_residues
MCGIVGYVGPREATDVIVRGLELLEYRGYDSAGIAILEDAEFQMRRSVGKLVNLRRRLHAEPTAGHQGIGHTRWATHGAV
TEANAHPHRDNSGRIVVIQNGIVENYLEIKGRLIEQGVRFHSQTDTEVIAQMLGLYTAEYGDFQRAFGQVMSELRGGNAV
VAMDQTQPDLILAARIGNAGAVVIGHGDTENFVASDLPAIVDYTQHMVFLEDGEMAIVRSTGVEYVKLDGTPISKTPTTV
AWDPVSAAKGGYKHFMHKEIFEQPRTTTDTLRGRVDLEAGRIELDGLTLSDAEMQKLDCIYAVACGTAWHACLINKYFIE
TLARVRVEVDYGSEFRYRNPVMNERSLLLALTQSGETVDTLAAMAEAREQGVKSVAILNAIGSQAGRLADGGAIYIHSGP
EISVASTKVFTGMLMAGYLFALRLAQARGTLTSAEIREHIQALIEIPAKIDTMLKDTAIYDQLADLYHHSTDMLYLGRWV
NAPIALEGALKMKEISYIHAEGYPAGEMKHGPIALIDERMPVICIATKDHVYEKMLSNVEQVIARGGKVIALVNPSDELV
RSKADHVIEVPETTPLLAAVLNVVPMQLFSYAMAVRRGADVDQPRNLAKSVTVE
>Mature_614_residues
MCGIVGYVGPREATDVIVRGLELLEYRGYDSAGIAILEDAEFQMRRSVGKLVNLRRRLHAEPTAGHQGIGHTRWATHGAV
TEANAHPHRDNSGRIVVIQNGIVENYLEIKGRLIEQGVRFHSQTDTEVIAQMLGLYTAEYGDFQRAFGQVMSELRGGNAV
VAMDQTQPDLILAARIGNAGAVVIGHGDTENFVASDLPAIVDYTQHMVFLEDGEMAIVRSTGVEYVKLDGTPISKTPTTV
AWDPVSAAKGGYKHFMHKEIFEQPRTTTDTLRGRVDLEAGRIELDGLTLSDAEMQKLDCIYAVACGTAWHACLINKYFIE
TLARVRVEVDYGSEFRYRNPVMNERSLLLALTQSGETVDTLAAMAEAREQGVKSVAILNAIGSQAGRLADGGAIYIHSGP
EISVASTKVFTGMLMAGYLFALRLAQARGTLTSAEIREHIQALIEIPAKIDTMLKDTAIYDQLADLYHHSTDMLYLGRWV
NAPIALEGALKMKEISYIHAEGYPAGEMKHGPIALIDERMPVICIATKDHVYEKMLSNVEQVIARGGKVIALVNPSDELV
RSKADHVIEVPETTPLLAAVLNVVPMQLFSYAMAVRRGADVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=35.4744525547445, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI205277386, Length=684, Percent_Identity=33.9181286549708, Blast_Score=373, Evalue=1e-103,
Organism=Escherichia coli, GI1790167, Length=618, Percent_Identity=41.9093851132686, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1788651, Length=176, Percent_Identity=29.5454545454545, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17539970, Length=718, Percent_Identity=33.983286908078, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17532899, Length=720, Percent_Identity=34.3055555555556, Blast_Score=367, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17532897, Length=495, Percent_Identity=35.1515151515151, Blast_Score=279, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6322745, Length=438, Percent_Identity=39.7260273972603, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6323731, Length=431, Percent_Identity=32.7146171693735, Blast_Score=217, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6323730, Length=221, Percent_Identity=37.10407239819, Blast_Score=116, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21357745, Length=686, Percent_Identity=35.7142857142857, Blast_Score=390, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67220; Mature: 67220

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYVGPREATDVIVRGLELLEYRGYDSAGIAILEDAEFQMRRSVGKLVNLRRRLHA
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCC
EPTAGHQGIGHTRWATHGAVTEANAHPHRDNSGRIVVIQNGIVENYLEIKGRLIEQGVRF
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
HSQTDTEVIAQMLGLYTAEYGDFQRAFGQVMSELRGGNAVVAMDQTQPDLILAARIGNAG
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCC
AVVIGHGDTENFVASDLPAIVDYTQHMVFLEDGEMAIVRSTGVEYVKLDGTPISKTPTTV
EEEEECCCCCCHHHHCCHHHHHHHHEEEEEECCCEEEEEECCCCEEEECCCCCCCCCCEE
AWDPVSAAKGGYKHFMHKEIFEQPRTTTDTLRGRVDLEAGRIELDGLTLSDAEMQKLDCI
EECCHHHCCCHHHHHHHHHHHHCCCCCHHHHCCEEEEECCEEEECCEEECCHHHHHHHHH
YAVACGTAWHACLINKYFIETLARVRVEVDYGSEFRYRNPVMNERSLLLALTQSGETVDT
HEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHH
LAAMAEAREQGVKSVAILNAIGSQAGRLADGGAIYIHSGPEISVASTKVFTGMLMAGYLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHH
ALRLAQARGTLTSAEIREHIQALIEIPAKIDTMLKDTAIYDQLADLYHHSTDMLYLGRWV
HHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHC
NAPIALEGALKMKEISYIHAEGYPAGEMKHGPIALIDERMPVICIATKDHVYEKMLSNVE
CCCEEEECCEEHHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHH
QVIARGGKVIALVNPSDELVRSKADHVIEVPETTPLLAAVLNVVPMQLFSYAMAVRRGAD
HHHHCCCCEEEEECCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VDQPRNLAKSVTVE
CCCHHHHHHHCCCC
>Mature Secondary Structure
MCGIVGYVGPREATDVIVRGLELLEYRGYDSAGIAILEDAEFQMRRSVGKLVNLRRRLHA
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCC
EPTAGHQGIGHTRWATHGAVTEANAHPHRDNSGRIVVIQNGIVENYLEIKGRLIEQGVRF
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
HSQTDTEVIAQMLGLYTAEYGDFQRAFGQVMSELRGGNAVVAMDQTQPDLILAARIGNAG
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCC
AVVIGHGDTENFVASDLPAIVDYTQHMVFLEDGEMAIVRSTGVEYVKLDGTPISKTPTTV
EEEEECCCCCCHHHHCCHHHHHHHHEEEEEECCCEEEEEECCCCEEEECCCCCCCCCCEE
AWDPVSAAKGGYKHFMHKEIFEQPRTTTDTLRGRVDLEAGRIELDGLTLSDAEMQKLDCI
EECCHHHCCCHHHHHHHHHHHHCCCCCHHHHCCEEEEECCEEEECCEEECCHHHHHHHHH
YAVACGTAWHACLINKYFIETLARVRVEVDYGSEFRYRNPVMNERSLLLALTQSGETVDT
HEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHH
LAAMAEAREQGVKSVAILNAIGSQAGRLADGGAIYIHSGPEISVASTKVFTGMLMAGYLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHH
ALRLAQARGTLTSAEIREHIQALIEIPAKIDTMLKDTAIYDQLADLYHHSTDMLYLGRWV
HHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHC
NAPIALEGALKMKEISYIHAEGYPAGEMKHGPIALIDERMPVICIATKDHVYEKMLSNVE
CCCEEEECCEEHHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHH
QVIARGGKVIALVNPSDELVRSKADHVIEVPETTPLLAAVLNVVPMQLFSYAMAVRRGAD
HHHHCCCCEEEEECCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VDQPRNLAKSVTVE
CCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA